index 0e8f983545..b85ef9958a 100644
--- spack/var/spack/repos/builtin/packages/charliecloud/package.py
+++ spack/var/spack/repos/builtin/packages/charliecloud/package.py
@@ -152,5 +152,7 @@ def configure_args(self):
         if "+squashfuse" in self.spec:
             squashfuse_prefix = "{0}".format(self.spec["squashfuse"].prefix)
             args.append("--with-libsquashfuse={0}".format(squashfuse_prefix))
+            fuse_include = self.spec["fuse"].prefix.include.fuse3
+            args.append("CFLAGS=-I{0}".format(fuse_include))