--- a/src/scripts/ganeshactl/CMakeLists.txt
+++ b/src/scripts/ganeshactl/CMakeLists.txt
@@ -160,7 +160,7 @@ if(Python3_FOUND)
     install(
       CODE
       "execute_process(WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}
-        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --prefix=\$ENV{DESTDIR}${CMAKE_INSTALL_PREFIX})"
+        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --install-layout=deb --root=\$ENV{DESTDIR})"
       )
   else()
     install(
--- a/src/scripts/gpfs-epoch/CMakeLists.txt
+++ b/src/scripts/gpfs-epoch/CMakeLists.txt
@@ -80,7 +80,7 @@ if(USE_FSAL_GPFS)
       install(
         CODE
         "execute_process(WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}
-        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --prefix=\$ENV{DESTDIR}${CMAKE_INSTALL_PREFIX} --install-scripts=\$ENV{DESTDIR}${LIBEXECDIR}/ganesha)"
+        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --install-layout=deb --root=\$ENV{DESTDIR} --install-scripts=./${LIBEXECDIR}/ganesha)"
         )
       else()
       install(
--- a/src/scripts/ganesha-top/CMakeLists.txt
+++ b/src/scripts/ganesha-top/CMakeLists.txt
@@ -78,7 +78,7 @@ if(USE_ADMIN_TOOLS)
       install(
         CODE
         "execute_process(WORKING_DIRECTORY ${CMAKE_CURRENT_BINARY_DIR}
-        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --prefix=\$ENV{DESTDIR}${CMAKE_INSTALL_PREFIX})"
+        COMMAND ${Python3_EXECUTABLE} ${SETUP_PY} install --skip-build --no-compile --install-layout=deb --root=\$ENV{DESTDIR})"
         )
     else()
       install(