-ENZREV
5.3.3.2

-ENZIRREV
1.1.1.34
1.14.13.13
2.5.1.10
4.1.1.33
5.4.99.7

-METINT
(S)-3-Hydroxy-3-methylglutaryl-CoA
(R)-mevalonate
CoA
Calcidiol
O2
calcitriol
H2O
Geranyl_diphosphate
diphosphate
trans,trans-farnesyl_diphosphate
ATP
(R)-5-diphosphomevalonate
ADP
phosphate
CO2
Isopentenyl_diphosphate
dimethylallyl_diphosphate
(S)-2,3-Epoxysqualene
lanosterol

-METEXT
NADPH
NADP+
isopentenyl_diphosphate

-CAT
1.1.1.34 : (S)-3-Hydroxy-3-methylglutaryl-CoA + 2 NADPH = (R)-mevalonate + CoA + 2 NADP+ .
1.14.13.13 : Calcidiol + NADPH + O2 = calcitriol + NADP+ + H2O .
2.5.1.10 : Geranyl_diphosphate + isopentenyl_diphosphate = diphosphate + trans,trans-farnesyl_diphosphate .
4.1.1.33 : ATP + (R)-5-diphosphomevalonate = ADP + phosphate + isopentenyl_diphosphate + CO2 .
5.3.3.2 : Isopentenyl_diphosphate = dimethylallyl_diphosphate .
5.4.99.7 : (S)-2,3-Epoxysqualene = lanosterol .