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#include "antsUtilities.h"
#include <algorithm>
#include "antsCommandLineParser.h"
#include "itkDiReCTImageFilter.h"
#include "itkDiscreteGaussianImageFilter.h"
#include "itkImage.h"
#include "ReadWriteData.h"
#include "itkTimeProbe.h"
#include <string>
#include <algorithm>
#include <vector>
namespace ants
{
template <typename TFilter>
class CommandIterationUpdate final : public itk::Command
{
public:
using Self = CommandIterationUpdate<TFilter>;
using Superclass = itk::Command;
using Pointer = itk::SmartPointer<Self>;
itkNewMacro(Self);
protected:
CommandIterationUpdate() = default;
public:
void
Execute(itk::Object * caller, const itk::EventObject & event) override
{
Execute((const itk::Object *)caller, event);
}
void
Execute(const itk::Object * object, const itk::EventObject & event) override
{
const auto * filter = dynamic_cast<const TFilter *>(object);
if (typeid(event) != typeid(itk::IterationEvent))
{
return;
}
std::cout << " Iteration " << filter->GetElapsedIterations() << " (of " << filter->GetMaximumNumberOfIterations()
<< "). ";
std::cout << "Current energy = " << filter->GetCurrentEnergy() << ". ";
if (filter->GetElapsedIterations() >= filter->GetConvergenceWindowSize())
{
std::cout << "(convergence value = " << filter->GetCurrentConvergenceMeasurement()
<< ", threshold = " << filter->GetConvergenceThreshold() << ")";
}
std::cout << std::endl;
}
};
template <unsigned int ImageDimension>
int
DiReCT(itk::ants::CommandLineParser * parser)
{
using RealType = float;
using LabelType = unsigned int;
using LabelImageType = itk::Image<LabelType, ImageDimension>;
typename LabelImageType::Pointer segmentationImage;
using ImageType = itk::Image<RealType, ImageDimension>;
typename ImageType::Pointer grayMatterProbabilityImage;
typename ImageType::Pointer whiteMatterProbabilityImage;
typename ImageType::Pointer thicknessPriorImage;
using DiReCTFilterType = itk::DiReCTImageFilter<LabelImageType, ImageType>;
typename DiReCTFilterType::Pointer direct = DiReCTFilterType::New();
using DirectLabelType = typename DiReCTFilterType::LabelType;
bool verbose = false;
typename itk::ants::CommandLineParser::OptionType::Pointer verboseOption = parser->GetOption("verbose");
if (verboseOption && verboseOption->GetNumberOfFunctions())
{
verbose = parser->Convert<bool>(verboseOption->GetFunction(0)->GetName());
}
if (verbose)
{
std::cout << "Running DiReCT for " << ImageDimension << "-dimensional images." << std::endl << std::endl;
}
//
// debugging information
//
typename itk::ants::CommandLineParser::OptionType::Pointer debugOption = parser->GetOption("print-debug-information");
if (debugOption && debugOption->GetNumberOfFunctions())
{
std::string value = debugOption->GetFunction()->GetName();
ConvertToLowerCase(value);
if (std::strcmp(value.c_str(), "true") || parser->Convert<int>(value) != 0)
{
direct->DebugOn();
}
}
//
// segmentation image
//
typename itk::ants::CommandLineParser::OptionType::Pointer segmentationImageOption =
parser->GetOption("segmentation-image");
if (segmentationImageOption && segmentationImageOption->GetNumberOfFunctions())
{
if (segmentationImageOption->GetFunction(0)->GetNumberOfParameters() == 0)
{
std::string inputFile = segmentationImageOption->GetFunction(0)->GetName();
ReadImage<LabelImageType>(segmentationImage, inputFile.c_str());
}
else if (segmentationImageOption->GetFunction(0)->GetNumberOfParameters() > 0)
{
std::string inputFile = segmentationImageOption->GetFunction(0)->GetParameter(0);
ReadImage<LabelImageType>(segmentationImage, inputFile.c_str());
if (segmentationImageOption->GetFunction(0)->GetNumberOfParameters() > 1)
{
auto grayMatterValue =
parser->Convert<DirectLabelType>(segmentationImageOption->GetFunction(0)->GetParameter(1));
direct->SetGrayMatterLabel(grayMatterValue);
}
if (segmentationImageOption->GetFunction(0)->GetNumberOfParameters() > 2)
{
auto whiteMatterValue =
parser->Convert<DirectLabelType>(segmentationImageOption->GetFunction(0)->GetParameter(2));
direct->SetWhiteMatterLabel(whiteMatterValue);
}
}
}
else
{
if (verbose)
{
std::cerr << "Segmentation image not specified." << std::endl;
}
return EXIT_FAILURE;
}
direct->SetSegmentationImage(segmentationImage);
//
// gray matter probability image
//
typename itk::ants::CommandLineParser::OptionType::Pointer grayMatterOption =
parser->GetOption("gray-matter-probability-image");
if (grayMatterOption && grayMatterOption->GetNumberOfFunctions())
{
std::string gmFile = grayMatterOption->GetFunction()->GetName();
ReadImage<ImageType>(grayMatterProbabilityImage, gmFile.c_str());
}
else
{
if (verbose)
{
std::cout << " Grey matter probability image not specified. "
<< "Creating one from the segmentation image using label value "
<< direct->GetGrayMatterLabel() << std::endl;
}
using ThresholderType = itk::BinaryThresholdImageFilter<LabelImageType, LabelImageType>;
typename ThresholderType::Pointer thresholder = ThresholderType::New();
thresholder->SetInput(segmentationImage);
thresholder->SetLowerThreshold(direct->GetGrayMatterLabel());
thresholder->SetUpperThreshold(direct->GetGrayMatterLabel());
thresholder->SetInsideValue(1);
thresholder->SetOutsideValue(0);
using SmootherType = itk::DiscreteGaussianImageFilter<LabelImageType, ImageType>;
typename SmootherType::Pointer smoother = SmootherType::New();
smoother->SetVariance(1.0);
smoother->SetUseImageSpacing(true);
smoother->SetMaximumError(0.01);
smoother->SetInput(thresholder->GetOutput());
smoother->Update();
grayMatterProbabilityImage = smoother->GetOutput();
}
direct->SetGrayMatterProbabilityImage(grayMatterProbabilityImage);
//
// white matter probability image
//
typename itk::ants::CommandLineParser::OptionType::Pointer whiteMatterOption =
parser->GetOption("white-matter-probability-image");
if (whiteMatterOption && whiteMatterOption->GetNumberOfFunctions())
{
std::string wmFile = whiteMatterOption->GetFunction(0)->GetName();
ReadImage<ImageType>(whiteMatterProbabilityImage, wmFile.c_str());
}
else
{
if (verbose)
{
std::cout << " White matter probability image not specified. "
<< "Creating one from the segmentation image using label value "
<< direct->GetWhiteMatterLabel() << std::endl;
}
using ThresholderType = itk::BinaryThresholdImageFilter<LabelImageType, ImageType>;
typename ThresholderType::Pointer thresholder = ThresholderType::New();
thresholder->SetInput(segmentationImage);
thresholder->SetLowerThreshold(direct->GetWhiteMatterLabel());
thresholder->SetUpperThreshold(direct->GetWhiteMatterLabel());
thresholder->SetInsideValue(1);
thresholder->SetOutsideValue(0);
using SmootherType = itk::DiscreteGaussianImageFilter<ImageType, ImageType>;
typename SmootherType::Pointer smoother = SmootherType::New();
smoother->SetVariance(1.0);
smoother->SetUseImageSpacing(true);
smoother->SetMaximumError(0.01);
smoother->SetInput(thresholder->GetOutput());
smoother->Update();
whiteMatterProbabilityImage = smoother->GetOutput();
}
direct->SetWhiteMatterProbabilityImage(whiteMatterProbabilityImage);
//
// label priors
//
typename itk::ants::CommandLineParser::OptionType::Pointer tpOption = parser->GetOption("thickness-prior-image");
if (tpOption && tpOption->GetNumberOfFunctions())
{
std::string labFile = tpOption->GetFunction(0)->GetName();
ReadImage<ImageType>(thicknessPriorImage, labFile.c_str());
direct->SetThicknessPriorImage(thicknessPriorImage);
}
//
// convergence options
//
typename itk::ants::CommandLineParser::OptionType::Pointer convergenceOption = parser->GetOption("convergence");
if (convergenceOption && convergenceOption->GetNumberOfFunctions())
{
if (convergenceOption->GetFunction(0)->GetNumberOfParameters() > 0)
{
direct->SetMaximumNumberOfIterations(
parser->Convert<unsigned int>(convergenceOption->GetFunction(0)->GetParameter(0)));
}
if (convergenceOption->GetFunction(0)->GetNumberOfParameters() > 1)
{
direct->SetConvergenceThreshold(parser->Convert<float>(convergenceOption->GetFunction(0)->GetParameter(1)));
}
if (convergenceOption->GetFunction(0)->GetNumberOfParameters() > 2)
{
direct->SetConvergenceWindowSize(
parser->Convert<unsigned int>(convergenceOption->GetFunction(0)->GetParameter(2)));
}
}
//
// thickness prior estimate
//
typename itk::ants::CommandLineParser::OptionType::Pointer thicknessPriorOption =
parser->GetOption("thickness-prior-estimate");
if (thicknessPriorOption && thicknessPriorOption->GetNumberOfFunctions())
{
direct->SetThicknessPriorEstimate(parser->Convert<RealType>(thicknessPriorOption->GetFunction(0)->GetName()));
}
//
// gradient step
//
typename itk::ants::CommandLineParser::OptionType::Pointer gradientStepOption = parser->GetOption("gradient-step");
if (gradientStepOption && gradientStepOption->GetNumberOfFunctions())
{
direct->SetInitialGradientStep(parser->Convert<RealType>(gradientStepOption->GetFunction(0)->GetName()));
}
//
// do B-spline smoothing?
//
typename itk::ants::CommandLineParser::OptionType::Pointer bsplineSmoothingOption =
parser->GetOption("use-bspline-smoothing");
if (bsplineSmoothingOption && bsplineSmoothingOption->GetNumberOfFunctions())
{
direct->SetUseBSplineSmoothing(parser->Convert<bool>(bsplineSmoothingOption->GetFunction(0)->GetName()));
}
//
// do matrix-based smoothing?
//
typename itk::ants::CommandLineParser::OptionType::Pointer maskedSmoothingOption =
parser->GetOption("use-masked-smoothing");
if (maskedSmoothingOption && maskedSmoothingOption->GetNumberOfFunctions())
{
direct->SetUseMaskedSmoothing(parser->Convert<bool>(maskedSmoothingOption->GetFunction(0)->GetName()));
}
//
// time points
//
typename itk::ants::CommandLineParser::OptionType::Pointer timePointsOption = parser->GetOption("time-points");
if (timePointsOption && timePointsOption->GetNumberOfFunctions())
{
direct->SetTimePoints(parser->ConvertVector<RealType>(timePointsOption->GetFunction(0)->GetParameter(0)));
if (timePointsOption->GetFunction(0)->GetNumberOfParameters() > 1)
{
direct->SetTimeSmoothingVariance(parser->Convert<float>(timePointsOption->GetFunction(0)->GetParameter(1)));
}
}
typename itk::ants::CommandLineParser::OptionType::Pointer restrictOption = parser->GetOption("restrict-deformation");
if (restrictOption && restrictOption->GetNumberOfFunctions())
{
direct->SetRestrictDeformation(parser->Convert<bool>(restrictOption->GetFunction(0)->GetName()));
}
//
// smoothing parameter for the velocity field
//
typename itk::ants::CommandLineParser::OptionType::Pointer smoothingVelocityFieldParameterOption =
parser->GetOption("smoothing-velocity-field-parameter");
if (smoothingVelocityFieldParameterOption && smoothingVelocityFieldParameterOption->GetNumberOfFunctions())
{
if (direct->GetUseBSplineSmoothing())
{
direct->SetBSplineSmoothingIsotropicMeshSpacing(
parser->Convert<RealType>(smoothingVelocityFieldParameterOption->GetFunction(0)->GetName()));
}
else
{
direct->SetSmoothingVelocityFieldVariance(
parser->Convert<RealType>(smoothingVelocityFieldParameterOption->GetFunction(0)->GetName()));
}
}
//
// smoothing variance for the hit and total images
//
typename itk::ants::CommandLineParser::OptionType::Pointer smoothingVarianceOption =
parser->GetOption("smoothing-variance");
if (smoothingVarianceOption && smoothingVarianceOption->GetNumberOfFunctions())
{
direct->SetSmoothingVariance(parser->Convert<RealType>(smoothingVarianceOption->GetFunction(0)->GetName()));
}
//
// number of integration points
//
typename itk::ants::CommandLineParser::OptionType::Pointer numberOfIntegrationPointsOption =
parser->GetOption("number-of-integration-points");
if (numberOfIntegrationPointsOption && numberOfIntegrationPointsOption->GetNumberOfFunctions())
{
direct->SetNumberOfIntegrationPoints(
parser->Convert<unsigned int>(numberOfIntegrationPointsOption->GetFunction(0)->GetName()));
}
//
// number of invert displacement field iterations
//
typename itk::ants::CommandLineParser::OptionType::Pointer numberOfInvertDisplacementFieldIterationsOption =
parser->GetOption("maximum-number-of-invert-displacement-field-iterations");
if (numberOfInvertDisplacementFieldIterationsOption &&
numberOfInvertDisplacementFieldIterationsOption->GetNumberOfFunctions())
{
direct->SetMaximumNumberOfInvertDisplacementFieldIterations(
parser->Convert<unsigned int>(numberOfInvertDisplacementFieldIterationsOption->GetFunction(0)->GetName()));
}
if (verbose)
{
using CommandType = CommandIterationUpdate<DiReCTFilterType>;
typename CommandType::Pointer observer = CommandType::New();
direct->AddObserver(itk::IterationEvent(), observer);
}
/**
* output
*/
typename itk::ants::CommandLineParser::OptionType::Pointer outputOption = parser->GetOption("output");
if (outputOption)
{
if (outputOption->GetFunction(0)->GetNumberOfParameters() > 1)
{
direct->SetIncludeCumulativeVelocityFields(true);
}
}
itk::TimeProbe timer;
timer.Start();
try
{
direct->Update(); // causes problems with ANTsR , unknown reason
}
catch (const itk::ExceptionObject & e)
{
if (verbose)
{
std::cerr << "Exception caught: " << e << std::endl;
}
return EXIT_FAILURE;
}
timer.Stop();
if (verbose)
{
direct->Print(std::cout, 3);
std::cout << "DiReCT elapsed time: " << timer.GetMean() << std::endl;
}
/**
* output
*/
if (outputOption && outputOption->GetNumberOfFunctions() > 0)
{
if (outputOption->GetFunction(0)->GetNumberOfParameters() == 0)
{
ANTs::WriteImage<ImageType>(direct->GetThicknessImage(), (outputOption->GetFunction(0)->GetName()).c_str());
}
else if (outputOption->GetFunction(0)->GetNumberOfParameters() > 0)
{
ANTs::WriteImage<ImageType>(direct->GetThicknessImage(), (outputOption->GetFunction(0)->GetParameter(0)).c_str());
if (outputOption->GetFunction(0)->GetNumberOfParameters() > 1)
{
direct->GetForwardCumulativeVelocityField()->Print(std::cout, 3);
ANTs::WriteImage<typename DiReCTFilterType::CumulativeVelocityFieldType>(direct->GetForwardCumulativeVelocityField(),
(outputOption->GetFunction(0)->GetParameter(1) + "ForwardVelocityField.nii.gz").c_str());
ANTs::WriteImage<typename DiReCTFilterType::CumulativeVelocityFieldType>(direct->GetInverseCumulativeVelocityField(),
(outputOption->GetFunction(0)->GetParameter(1) + "InverseVelocityField.nii.gz").c_str());
}
}
}
return EXIT_SUCCESS;
}
void
KellyKapowskiInitializeCommandLineOptions(itk::ants::CommandLineParser * parser)
{
using OptionType = itk::ants::CommandLineParser::OptionType;
{
std::string description = std::string("This option forces the image to be treated as a specified-") +
std::string("dimensional image. If not specified, DiReCT tries to ") +
std::string("infer the dimensionality from the input image.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("image-dimensionality");
option->SetShortName('d');
option->SetUsageOption(0, "2/3");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("A segmentation image must be supplied labeling the gray") +
std::string("and white matters. Default values = 2 and 3, respectively.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("segmentation-image");
option->SetShortName('s');
option->SetUsageOption(0, "imageFilename");
option->SetUsageOption(1, "[imageFilename,<grayMatterLabel=2>,<whiteMatterLabel=3>]");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("In addition to the segmentation image, a gray matter ") +
std::string("probability image can be used. If no such image is ") +
std::string("supplied, one is created using the segmentation image ") +
std::string("and a variance of 1.0 mm.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("gray-matter-probability-image");
option->SetShortName('g');
option->SetUsageOption(0, "imageFilename");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("In addition to the segmentation image, a white matter ") +
std::string("probability image can be used. If no such image is ") +
std::string("supplied, one is created using the segmentation image ") +
std::string("and a variance of 1.0 mm.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("white-matter-probability-image");
option->SetShortName('w');
option->SetUsageOption(0, "imageFilename");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Convergence is determined by fitting a line to the normalized energy ") +
std::string("profile of the last N iterations (where N is specified by ") +
std::string("the window size) and determining the slope which is then ") +
std::string("compared with the convergence threshold.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("convergence");
option->SetShortName('c');
option->SetUsageOption(0, "[<numberOfIterations=45>,<convergenceThreshold=0.0>,<convergenceWindowSize=10>]");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("Provides a prior constraint on the final thickness measurement. Default = 10 mm.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("thickness-prior-estimate");
option->SetShortName('t');
option->SetUsageOption(0, "thicknessPriorEstimate");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("An image containing spatially varying prior thickness values.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("thickness-prior-image");
option->SetShortName('a');
option->SetUsageOption(0, "thicknessPriorFileName");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Gradient step size for the optimization. Default = 0.025.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("gradient-step");
option->SetShortName('r');
option->SetUsageOption(0, "stepSize");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("Defines the Gaussian smoothing of the hit and total images. Default = 1.0 mm.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("smoothing-variance");
option->SetShortName('l');
option->SetUsageOption(0, "variance");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("Defines the Gaussian smoothing of the velocity field (default = 1.5 voxels).") +
std::string("If the b-spline smoothing option is chosen, then this ") +
std::string("defines the isotropic mesh spacing for the smoothing spline (default = 15 mm).");
OptionType::Pointer option = OptionType::New();
option->SetLongName("smoothing-velocity-field-parameter");
option->SetShortName('m');
option->SetUsageOption(0, "variance");
option->SetUsageOption(1, "isotropicMeshSpacing");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("Sets the option for B-spline smoothing of the velocity field.") + std::string("Default = false.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("use-bspline-smoothing");
option->SetShortName('b');
option->SetUsageOption(0, "1/(0)");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Sets the option for masked-based smoothing of the velocity field.") +
std::string("Default = false.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("use-masked-smoothing");
option->SetShortName('x');
option->SetUsageOption(0, "1/(0)");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Time points for irregularly spaced time samples and ") +
std::string("time-variance with which to compute distance metric. ") +
std::string("The user specifies [0.0x1.2x4.5,3] for input with 3 time ") +
std::string("slices where the vector of numeric value defines the time ") +
std::string("of sampling e.g. in years and the scalar value (here \'3\')") +
std::string("defines the variance.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("time-points");
option->SetShortName('q');
option->SetUsageOption(0, "1");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Restrict the last dimension's deformation. Meant for use ") +
std::string("with multiple time points. Default = false.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("restrict-deformation");
option->SetShortName('e');
option->SetUsageOption(0, "1/(0)");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Number of compositions of the diffeomorphism per iteration. Default = 10.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("number-of-integration-points");
option->SetShortName('n');
option->SetUsageOption(0, "numberOfPoints");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("Maximum number of iterations for estimating the invert displacement field. Default = 20.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("maximum-number-of-invert-displacement-field-iterations");
option->SetShortName('p');
option->SetUsageOption(0, "numberOfIterations");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description =
std::string("The output consists of a thickness map defined in the ") + std::string("segmented gray matter. ");
OptionType::Pointer option = OptionType::New();
option->SetLongName("output");
option->SetShortName('o');
option->SetUsageOption(0, "imageFileName");
option->SetUsageOption(1, "[imageFileName,cumulativeVelocityFieldFileNamePrefix]");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Verbose output.");
OptionType::Pointer option = OptionType::New();
option->SetShortName('v');
option->SetLongName("verbose");
option->SetUsageOption(0, "(0)/1");
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Print the help menu (short version).");
OptionType::Pointer option = OptionType::New();
option->SetShortName('h');
option->SetDescription(description);
parser->AddOption(option);
}
{
std::string description = std::string("Print the help menu.");
OptionType::Pointer option = OptionType::New();
option->SetLongName("help");
option->SetDescription(description);
parser->AddOption(option);
}
}
// entry point for the library; parameter 'args' is equivalent to 'argv' in (argc,argv) of commandline parameters to
// 'main()'
int
KellyKapowski(std::vector<std::string> args, std::ostream * /*out_stream = nullptr */)
{
// put the arguments coming in as 'args' into standard (argc,argv) format;
// 'args' doesn't have the command name as first, argument, so add it manually;
// 'args' may have adjacent arguments concatenated into one argument,
// which the parser should handle
args.insert(args.begin(), "KellyKapowski");
int argc = args.size();
char ** argv = new char *[args.size() + 1];
for (unsigned int i = 0; i < args.size(); ++i)
{
// allocate space for the string plus a null character
argv[i] = new char[args[i].length() + 1];
std::strncpy(argv[i], args[i].c_str(), args[i].length());
// place the null character in the end
argv[i][args[i].length()] = '\0';
}
argv[argc] = nullptr;
// class to automatically cleanup argv upon destruction
class Cleanup_argv
{
public:
Cleanup_argv(char ** argv_, int argc_plus_one_)
: argv(argv_)
, argc_plus_one(argc_plus_one_)
{}
~Cleanup_argv()
{
for (unsigned int i = 0; i < argc_plus_one; ++i)
{
delete[] argv[i];
}
delete[] argv;
}
private:
char ** argv;
unsigned int argc_plus_one;
};
Cleanup_argv cleanup_argv(argv, argc + 1);
// antscout->set_stream( out_stream );
itk::ants::CommandLineParser::Pointer parser = itk::ants::CommandLineParser::New();
parser->SetCommand(argv[0]);
std::string commandDescription = std::string("DiReCT is a registration based estimate of cortical ") +
std::string("thickness. It was published in S. R. Das, B. B. ") +
std::string("Avants, M. Grossman, and J. C. Gee, Registration based ") +
std::string("cortical thickness measurement, Neuroimage 2009, ") +
std::string("45:867--879. See also N. J. Tustison, P. A. Cook, ") +
std::string("A. Klein, G. Song, S. R. Das, J. T. Duda, B M. Kandel, ") +
std::string("N. van Strien, J. R. Stone, J. C. Gee, and B. B. Avants. ") +
std::string("Large-Scale Evaluation of ANTs and FreeSurfer Cortical ") +
std::string("Thickness Measurements. NeuroImage, 99:166-179, Oct 2014.");
parser->SetCommandDescription(commandDescription);
KellyKapowskiInitializeCommandLineOptions(parser);
if (parser->Parse(argc, argv) == EXIT_FAILURE)
{
return EXIT_FAILURE;
}
if (argc == 1)
{
parser->PrintMenu(std::cout, 5, false);
return EXIT_FAILURE;
}
else if (parser->GetOption("help")->GetFunction() &&
parser->Convert<bool>(parser->GetOption("help")->GetFunction()->GetName()))
{
parser->PrintMenu(std::cout, 5, false);
return EXIT_SUCCESS;
}
else if (parser->GetOption('h')->GetFunction() &&
parser->Convert<bool>(parser->GetOption('h')->GetFunction()->GetName()))
{
parser->PrintMenu(std::cout, 5, true);
return EXIT_SUCCESS;
}
// Get dimensionality
unsigned int dimension = 3;
itk::ants::CommandLineParser::OptionType::Pointer dimOption = parser->GetOption("image-dimensionality");
if (dimOption && dimOption->GetNumberOfFunctions() > 0)
{
dimension = parser->Convert<unsigned int>(dimOption->GetFunction(0)->GetName());
}
else
{
// Read in the first intensity image to get the image dimension.
std::string filename;
itk::ants::CommandLineParser::OptionType::Pointer imageOption = parser->GetOption("segmentation-image");
if (imageOption && imageOption->GetNumberOfFunctions() > 0)
{
if (imageOption->GetFunction(0)->GetNumberOfParameters() > 0)
{
filename = imageOption->GetFunction(0)->GetParameter(0);
}
else
{
filename = imageOption->GetFunction(0)->GetName();
}
}
else
{
std::cout << "No input images were specified. Specify an input "
<< " segmentation image with the -s option" << std::endl;
return EXIT_FAILURE;
}
itk::ImageIOBase::Pointer imageIO =
itk::ImageIOFactory::CreateImageIO(filename.c_str(), itk::IOFileModeEnum::ReadMode);
if (!imageIO)
{
std::cout << "Could not create ImageIO object for file " << filename.c_str() << std::endl;
return EXIT_FAILURE;
}
dimension = imageIO->GetNumberOfDimensions();
}
switch (dimension)
{
case 2:
{
return DiReCT<2>(parser);
}
break;
case 3:
{
return DiReCT<3>(parser);
}
break;
case 4:
{
return DiReCT<4>(parser);
}
break;
default:
std::cout << "Unsupported dimension" << std::endl;
return EXIT_FAILURE;
}
return EXIT_SUCCESS;
}
} // namespace ants
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