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<title>The Nucleosome</title>
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<a href="index.html?action=clearAll&module=common_functions">Main page</a> > <a href=nucleo1_de.html?action=loadProject&module=common_functions&filename=projects/NCP_start.bvp">The Nucleosome I</a> > The Nucleosome II
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<h1>The Nucleosome</h1>
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On the previous page, you have seen the complete structure of the nucleosome - but what are its constituent parts? Have a look at the next structure, you will notice that the core of the nucleosome consists of several similar porteins.
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How many proteins make up the histone core of the nucleosome? </br>
<a href="javascript:showAnswer('numberone')">The correct answer is:</a>
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The correct answer is: The core consists of 8 histones.<br>
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The histones are organised in a pairwise manner, i.e. each two histones build a so-called dimer. Their orientation in this dimer structure reminds of two people shaking hands (hence, this structural motif is called a "handshake motif"). The two histones build a firm, interleaved unit that is the basis of the nucleosome. The histone core is constructed like a puzzle; in the first step, a tetramer is deposited onto the DNA.
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The correct answer: A tetramer consists of 4 histones. <br>
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The tetramer is flanked by 2 dimers in the subsequent step and thus complete the histone core and the nucleosome, respectively.
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Can you identify the constituent parts (DNA and 8 histones) of the complete nucleosome in the following structure?
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