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package assemble;
import java.util.ArrayList;
import java.util.concurrent.atomic.AtomicInteger;
import kmer.AbstractKmerTableSet;
import kmer.KmerTableSet;
import shared.Timer;
import ukmer.KmerTableSetU;
/**
* Designed for removal of dead ends (aka hairs).
* @author Brian Bushnell
* @date Jun 26, 2015
*
*/
public abstract class Shaver extends ShaveObject {
/*--------------------------------------------------------------*/
/*---------------- Factory ----------------*/
/*--------------------------------------------------------------*/
public static final Shaver makeShaver(AbstractKmerTableSet tables, int threads){
return makeShaver(tables, threads, 1, 1, 1, 1, 3, 100, 100, true, true);
}
public static final Shaver makeShaver(AbstractKmerTableSet tables, int threads,
int minCount, int maxCount, int minSeed, int minCountExtend, float branchMult2, int maxLengthToDiscard, int maxDistanceToExplore,
boolean removeHair, boolean removeBubbles){
final Class<?> c=tables.getClass();
if(c==KmerTableSet.class){
return new Shaver1((KmerTableSet)tables, threads, minCount, maxCount, minSeed, minCountExtend, branchMult2,
maxLengthToDiscard, maxDistanceToExplore, removeHair, removeBubbles);
}else if(c==KmerTableSetU.class){
return new Shaver2((KmerTableSetU)tables, threads, minCount, maxCount, minSeed, minCountExtend, branchMult2,
maxLengthToDiscard, maxDistanceToExplore, removeHair, removeBubbles);
}
throw new RuntimeException("Unhandled class "+c);
}
/*--------------------------------------------------------------*/
/*---------------- Constructor ----------------*/
/*--------------------------------------------------------------*/
public Shaver(AbstractKmerTableSet tables_, int threads_,
int minCount_, int maxCount_, int minSeed_, int minCountExtend_, float branchMult2_, int maxLengthToDiscard_, int maxDistanceToExplore_,
boolean removeHair_, boolean removeBubbles_){
threads=threads_;
minCount=minCount_;
maxCount=maxCount_;
minSeed=minSeed_;
minCountExtend=minCountExtend_;
branchMult2=branchMult2_;
maxLengthToDiscard=maxLengthToDiscard_;
maxDistanceToExplore=maxDistanceToExplore_;
removeHair=removeHair_;
removeBubbles=removeBubbles_;
kbig=tables_.kbig();
}
/*--------------------------------------------------------------*/
/*---------------- Outer Methods ----------------*/
/*--------------------------------------------------------------*/
abstract AbstractExploreThread makeExploreThread(int id_);
abstract AbstractShaveThread makeShaveThread(int id_);
public final long shave(int minCount_, int maxCount_){
minCount=minCount_;
maxCount=maxCount_;
return shave();
}
public final long shave(){
assert(minSeed>=minCount) : "Required: mincount >= minSeed >= maxCount. "+minCount+", "+minSeed+", "+maxCount;
assert(minSeed<=maxCount) : "Required: mincount >= minSeed >= maxCount. "+minCount+", "+minSeed+", "+maxCount;
assert(removeHair || removeBubbles);
Timer t=new Timer();
long kmersTestedTemp=0;
long deadEndsFoundTemp=0;
long kmersRemovedTemp=0;
long bubblesFoundTemp=0;
tables().initializeOwnership();
countMatrix=new long[8][8];
removeMatrix=new long[8][8];
{
nextTable.set(0);
nextVictims.set(0);
/* Create Explorethreads */
ArrayList<AbstractExploreThread> alpt=new ArrayList<AbstractExploreThread>(threads);
for(int i=0; i<threads; i++){alpt.add(makeExploreThread(i));}
for(AbstractExploreThread pt : alpt){pt.start();}
/* Wait for threads to die, and gather statistics */
for(AbstractExploreThread pt : alpt){
while(pt.getState()!=Thread.State.TERMINATED){
try {
pt.join();
} catch (InterruptedException e) {
// TODO Auto-generated catch block
e.printStackTrace();
}
}
kmersTestedTemp+=pt.kmersTestedT;
deadEndsFoundTemp+=pt.deadEndsFoundT;
bubblesFoundTemp+=pt.bubblesFoundT;
for(int i=0; i<countMatrix.length; i++){
for(int j=0; j<countMatrix[i].length; j++){
countMatrix[i][j]+=pt.countMatrixT[i][j];
removeMatrix[i][j]+=pt.removeMatrixT[i][j];
}
}
}
kmersTested+=kmersTestedTemp;
deadEndsFound+=deadEndsFoundTemp;
bubblesFound+=bubblesFoundTemp;
t.stop();
outstream.println("Tested "+kmersTestedTemp+" kmers.");
outstream.println("Found "+deadEndsFoundTemp+" dead ends.");
outstream.println("Found "+bubblesFoundTemp+" bubbles.");
outstream.println("Search time: "+t);
}
{
t.start();
nextTable.set(0);
nextVictims.set(0);
/* Create Shavethreads */
ArrayList<AbstractShaveThread> alpt=new ArrayList<AbstractShaveThread>(threads);
for(int i=0; i<threads; i++){alpt.add(makeShaveThread(i));}
for(AbstractShaveThread pt : alpt){pt.start();}
for(AbstractShaveThread pt : alpt){
while(pt.getState()!=Thread.State.TERMINATED){
try {
pt.join();
} catch (InterruptedException e) {
// TODO Auto-generated catch block
e.printStackTrace();
}
}
kmersRemovedTemp+=pt.kmersRemovedT;
}
kmersRemoved+=kmersRemovedTemp;
outstream.println("Removed "+kmersRemovedTemp+" kmers.");
t.stop();
outstream.println("Shave time: "+t);
}
if(printEventCounts){
outstream.println("\nEvent counts:");
for(int i=0; i<countMatrix.length; i++){
for(int j=0; j<countMatrix[i].length; j++){
outstream.print(countMatrix[i][j]+" ");
}
outstream.println();
}
outstream.println("\nRemoval counts:");
for(int i=0; i<removeMatrix.length; i++){
for(int j=0; j<removeMatrix[i].length; j++){
outstream.print(removeMatrix[i][j]+" ");
}
outstream.println();
}
}
return kmersRemovedTemp;
}
/*--------------------------------------------------------------*/
/*---------------- Fields ----------------*/
/*--------------------------------------------------------------*/
public long kmersTested=0;
public long deadEndsFound=0;
public long bubblesFound=0;
public long kmersRemoved=0;
/*--------------------------------------------------------------*/
/*---------------- Final Fields ----------------*/
/*--------------------------------------------------------------*/
abstract AbstractKmerTableSet tables();
final int kbig;
final int threads;
int minCount;
int maxCount;
final int minSeed;
final int minCountExtend;
final float branchMult2;
final int maxLengthToDiscard;
final int maxDistanceToExplore;
final boolean removeHair;
final boolean removeBubbles;
static boolean startFromHighCounts=true; //True is much faster, but decreases contiguity.
static boolean shaveFast=true;
static final boolean shaveVFast=false; //True is faster, but slightly decreases contiguity.
private long[][] countMatrix;
private long[][] removeMatrix;
/** For controlling access to tables */
final AtomicInteger nextTable=new AtomicInteger(0);
/** For controlling access to victim buffers */
final AtomicInteger nextVictims=new AtomicInteger(0);
}
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