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package bin;
import java.util.ArrayList;
import java.util.Iterator;
import shared.Tools;
import sketch.Sketch;
import sketch.SketchMakerMini;
import stream.Read;
import structures.IntHashMap;
import structures.IntHashSet;
import tracker.EntropyTracker;
public class Cluster extends Bin {
public Cluster(int id_) {id=id_;}
public Cluster(Contig c) {
id=c.id();
add(c);
}
@Override
public String name() {return contigs.get(0).name;}
@Override
public boolean isCluster() {return true;}
@Override
public Cluster toCluster() {return this;}
@Override
public Cluster cluster() {return this;}
@Override
public final int id() {return id;}
public boolean pure(float fraction) {return nonDominantSize<=size*fraction;}
public float minContigDepth() {
float d=contigs.size()==0 ? 0 : contigs.get(0).depth();
for(Contig c : contigs) {d=Math.min(c.depth(), d);}
return d;
}
public float maxContigDepth() {
float d=0;
for(Contig c : contigs) {d=Math.max(c.depth(), d);}
return d;
}
@Override
@Deprecated
public void setID(int id_) {
throw new RuntimeException("Not supported.");
}
public Cluster add(Bin b) {
if(b.getClass()==Cluster.class) {return add((Cluster)b);}
else {return add((Contig)b);}
}
public Cluster add(Cluster clust) {
assert(clust!=this) : id();
for(Contig c : clust.contigs) {add(c);}
clust.contigs=null;
// assert(isValid());
return this;
}
boolean sameCluster(Bin b) {
if(contigSet.contains(b.id())) {return true;}
return b.isCluster() && ((Cluster)b).contigSet.contains(id());
}
public synchronized Cluster add(Contig c) {
timestamp=globalTime;
// verbose=(id()==52 || id()==3 || id()==3 || c.id()==52 || c.id()==3 || c.id()==3);
// if(verbose) {
// System.err.println("Adding "+c.id()+" to "+this.id()+(c.cluster==null ? "" : " from "+c.cluster.id));
// assert(c.cluster==null || c.cluster.id()!=3);
// }
// assert(c.isValid());
assert(c.cluster!=this);
assert(!contigSet.contains(c.id()));
c.cluster=this;
final long size2=size()+c.size();
final float invSize2=1f/size2;
if(contigs.size()==0) {
topHit=c.topHit;
secondHit=c.secondHit;
taxid=c.taxid;
genusTaxid=c.genusTaxid;
labelTaxid=c.labelTaxid;
sketchedSize=c.sketchedSize;
entropy=c.entropy;
// acRatio=c.acRatio;
}else {
if(labelTaxid<1 || (c.labelTaxid!=labelTaxid && c.size()>=0.05f*size())) {nonDominantSize+=c.size();}
// assert(isValid());
entropy=(entropy*size()+c.entropy*c.size())*invSize2;
// acRatio=(acRatio*size()+c.acRatio*c.size())*invSize2;
}
contigs.add(c);
contigSet.add(c.id());
numTetramers+=c.numTetramers;
numPentamers+=c.numPentamers;
// invKmers=1f/numTetramers;
if(tetramers==null) {tetramers=c.tetramers.clone();}
else {Tools.add(tetramers, c.tetramers);}
if(c.dimers!=null) {
if(dimers==null) {dimers=c.dimers.clone();}
else {Tools.add(dimers, c.dimers);}
strandedness=EntropyTracker.strandedness(dimers, 2);
}
if(c.trimers!=null) {
if(trimers==null) {trimers=c.trimers.clone();}
else {Tools.add(trimers, c.trimers);}
}
if(c.pentamers!=null) {
if(pentamers==null) {pentamers=c.pentamers.clone();}
else {Tools.add(pentamers, c.pentamers);}
}
if(c.pairMap!=null) {
if(pairMap==null) {pairMap=new IntHashMap(5);}
// pairMap.incrementAll(c.pairMap);//Remember, the targets are contig IDs.
pairMap.setToMax(c.pairMap);
}
if(numDepths()==0) {//Empty cluster
assert(size==0 || grading);
for(int i=0, max=c.numDepths(); i<max; i++) {appendDepth(c.depth(i));}
}else {//Nonempty cluster
assert(c.numDepths()==numDepths()) : c.numDepths()+", "+numDepths();
float cmult=invSize2*c.size();
float bmult=invSize2*size;
for(int i=0, max=c.numDepths(); i<max; i++) {
float cdepth=c.depth(i)*cmult;
float bdepth=depth(i)*bmult;
setDepth(cdepth+bdepth, i);
}
}
if(numDepths()>1) {
fillNormDepth();
}
avgDepthValid=false;
size=size2;
gcSum+=c.gcSum;
// assert(gcSum>0 || grading) : gcSum+", "+c.gcSum+", "+c.size()+", "+c.numContigs();
// assert(isValid());
// assert(c.isValid());
return this;
}
@Override
public long size() {return size;}
@Override
public Sketch toSketch(SketchMakerMini smm, Read r) {
String name=Long.toString(id());
if(r==null) {r=new Read(null, null, name, id());}
r.id=name;
r.numericID=id();
for(Contig c : contigs) {
r.bases=c.bases;
smm.processReadNucleotide(r);
}
return smm.toSketch(0);
}
@Override
public boolean isValid() {
if(id()<0) {
assert(false) : id()+", "+contigSet;
return false;
}
if(numDepths()<1) {
assert(false) : id()+", "+contigSet;
return false;
}
if(tetramers==null) {
assert(false) : id()+", "+contigSet;
return false;
}
if(contigs.isEmpty()) {
assert(false) : id()+", "+contigSet;
return false;
}
for(Contig c : contigs) {
if(c.cluster!=this) {
assert(c.cluster!=null);
assert(false) : "Cluster "+id()+" contains a contig "+c.id()+" that points to "+c.cluster().id()+"\n"
+ " set="+contigSet+", c.set="+c.cluster.contigSet+"\n"+contigs+"\n"+c.cluster.contigs+"\n";
return false;
}
if(!contigSet.contains(c.id())) {
assert(false) : id()+", "+contigSet;
return false;
}
// if(c.pairMap!=null && !c.pairMap.isEmpty()) {
// for(KeyValue kv : KeyValue.toList(c.pairMap)) {
// int value2=pairMap.get(kv.key);
// assert(value2>=kv.value) : c.pairMap+"\n"+pairMap;
// }
// }
}
return true;
}
public void clear() {
size=0;
contigs.clear();
contigSet.clear();
pairMap=null;
numTetramers=0;
numPentamers=0;
// invKmers=0;
dimers=null;
trimers=null;
tetramers=null;
pentamers=null;
gcSum=0;
sketchedSize=0;
clearDepth();
completeness=contam=entropy=strandedness=score=0;
dest=0;
taxid=genusTaxid=labelTaxid=0;
topHit=secondHit=null;
nonDominantSize=0;
}
@Override
public int numContigs() {return contigs==null ? 0 : contigs.size();}
@Override
public Iterator<Contig> iterator() {
return contigs.iterator();
}
final int id;
public long size;
public ArrayList<Contig> contigs=new ArrayList<Contig>(8);
public IntHashSet contigSet=new IntHashSet(5);
private int timestamp=-1;
long nonDominantSize=0;
}
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