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/**
* BioJava development code
*
* This code may be freely distributed and modified under the
* terms of the GNU Lesser General Public Licence. This should
* be distributed with the code. If you do not have a copy,
* see:
*
* http://www.gnu.org/copyleft/lesser.html
*
* Copyright for this code is held jointly by the individual
* authors. These should be listed in @author doc comments.
*
* For more information on the BioJava project and its aims,
* or to join the biojava-l mailing list, visit the home page
* at:
*
* http://www.biojava.org/
*
*/
package org.biojava.bio.symbol;
import java.util.HashSet;
import java.util.Random;
import java.util.Set;
import junit.framework.Test;
import junit.framework.TestCase;
import junit.framework.TestSuite;
import org.biojava.bio.seq.DNATools;
import org.biojava.bio.seq.RNATools;
import org.biojava.bio.seq.io.ChunkedSymbolListFactory;
import org.biojava.utils.ChangeVetoException;
/**
* JUnit test for SymbolList objects
* @author David Huen
* @since 1.3
*/
public class SymbolListTest extends TestCase
{
// SymbolList lengths to run tests at.
int testLengths[] = {100, 16384, 32000, 100000};
// number of times to repeat each test to deal with chance
// matches in last symbol.
int noRepeats = 8;
/**
* an interface for internal classes
*/
private interface SymListFactory {
public SymbolList createSymbolList(Symbol [] array, FiniteAlphabet alpha, int length);
}
public SymbolListTest(String string)
{
super(string);
}
/**
* creates a random SymbolList
*
* @param the Alphabet from which Symbols are to be drawn. Can include ambiguity symbols.
*/
protected Symbol [] createRandomSymbolArray(FiniteAlphabet alpha, int length)
throws Exception
{
int alfaSize = alpha.size();
AlphabetIndex indx = AlphabetManager.getAlphabetIndex(alpha);
Random rand = new Random();
Symbol [] array = new Symbol [length];
for (int i=0; i < length; i++) {
array[i] = indx.symbolForIndex(rand.nextInt(alfaSize));
}
return array;
}
/**
* compares a SymbolList against a Symbol array
*/
protected boolean compareSymbolLists(SymbolList list, Symbol [] array)
{
// array must be at least as long as SymbolList
int length = list.length();
if (length > array.length) return false;
// compare symbol lists across length
for (int i =1; i <= length; i++) {
if (list.symbolAt(i) != array[i-1]) return false;
}
return true;
}
/**
* Note that arrayAlpha <b>MUST NOT</b> have Symbols that are incompatible with symListAlpha!!!
* e.g. arrayAlpha may have ambiguity symbols in it that are only implicitly defined by symListAlpha.
* @param arrayAlpha the Alphabet from which the Symbols in the Symbol[] are to be drawn.
* @param symListAlpha the Alphabet on which the symbolList is to be defined.
*/
protected boolean runSymbolListTest(FiniteAlphabet arrayAlpha, FiniteAlphabet symListAlpha, int length, SymListFactory factory)
throws Exception
{
// create a Symbol array of the kind required
Symbol [] array = createRandomSymbolArray(arrayAlpha, length);
assertNotNull(array);
// create the required SymbolList
SymbolList symList = factory.createSymbolList(array, symListAlpha, length);
// if (symList == null) return false;
assertNotNull(symList);
// verify and return result.
return compareSymbolLists(symList, array);
}
/**
* runs repeated tests for the constructor
* that takes a SymbolList argument
*/
private boolean runRepeatedSymbolListTests(FiniteAlphabet arrayAlpha, FiniteAlphabet symListAlpha, SymListFactory factory)
throws Exception
{
for (int i=0; i < testLengths.length; i++) {
// setup test for specified length
int length = testLengths[i];
for (int j=0; j < noRepeats; j++ ) {
assertTrue(runSymbolListTest(arrayAlpha, symListAlpha, length, factory));
}
}
return true;
}
/**
* set that generates a DNA alphabet including ambiguity symbols.
*/
private FiniteAlphabet generateAmbiguousDNA()
{
FiniteAlphabet dna = DNATools.getDNA();
FiniteAlphabet ambiguous = new SimpleAlphabet();
try {
ambiguous.addSymbol(DNATools.a());
ambiguous.addSymbol(DNATools.c());
ambiguous.addSymbol(DNATools.g());
ambiguous.addSymbol(DNATools.t());
Set chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.c());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.g());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.c());
chars.add(DNATools.g());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.c());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.g());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.c());
chars.add(DNATools.g());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.c());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.a());
chars.add(DNATools.g());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars = new HashSet();
chars.add(DNATools.c());
chars.add(DNATools.g());
chars.add(DNATools.t());
ambiguous.addSymbol(dna.getAmbiguity(chars));
chars.add(DNATools.n());
return ambiguous;
}
catch (IllegalSymbolException ise) {
return null;
}
catch (ChangeVetoException cve) {
return null;
}
}
/**
* test for PackedSymbolList that implements ambiguity symbols.
*/
public void testPackedSymbolListWithAmbiguitySymbols()
throws Exception
{
// create an alphabet with ambiguity symbols
FiniteAlphabet symListAlpha = (FiniteAlphabet) DNATools.getDNA();
FiniteAlphabet arrayAlpha = generateAmbiguousDNA();
assertNotNull(arrayAlpha);
assertNotNull(symListAlpha);
// create a PackedSymbolList that supports ambiguity symbols
SymListFactory factory = new SymListFactory () {
public SymbolList createSymbolList(Symbol [] array, FiniteAlphabet alpha, int length)
{
try {
// get a packing
Packing pack = PackingFactory.getPacking(DNATools.getDNA(), true);
assertNotNull(pack);
assertNotNull(array);
assertNotNull(alpha);
assertTrue(length > 0);
return new PackedSymbolList(pack, array, length, alpha);
}
catch (IllegalAlphabetException iae) {
iae.printStackTrace();
return null;
}
}
};
// exercise the PackedSymbolList implementation
assertTrue(runRepeatedSymbolListTests(arrayAlpha, symListAlpha, factory));
}
/**
* test for SimpleSymbolList that implements ambiguity symbols.
*/
public void testSimpleSymbolListWithAmbiguitySymbols()
throws Exception
{
// create an alphabet with ambiguity symbols
FiniteAlphabet symListAlpha = (FiniteAlphabet) DNATools.getDNA();
FiniteAlphabet arrayAlpha = generateAmbiguousDNA();
assertNotNull(arrayAlpha);
assertNotNull(symListAlpha);
// create a SimpleSymbolList that supports ambiguity symbols
SymListFactory factory = new SymListFactory () {
public SymbolList createSymbolList(Symbol [] array, FiniteAlphabet alpha, int length)
{
assertNotNull(array);
assertNotNull(alpha);
assertTrue(length > 0);
return new SimpleSymbolList(array, length, alpha);
}
};
// exercise the PackedSymbolList implementation
assertTrue(runRepeatedSymbolListTests(arrayAlpha, symListAlpha, factory));
}
/**
* test for PackedSymbolList that does not implement ambiguity symbols.
*/
public void testPackedSymbolListWithoutAmbiguitySymbols()
throws Exception
{
// create an alphabet without ambiguity symbols
FiniteAlphabet symListAlpha = (FiniteAlphabet) DNATools.getDNA();
assertNotNull(symListAlpha);
// create a PackedSymbolList that supports ambiguity symbols
SymListFactory factory = new SymListFactory () {
public SymbolList createSymbolList(Symbol [] array, FiniteAlphabet alpha, int length)
{
try {
// get a packing
Packing pack = PackingFactory.getPacking(DNATools.getDNA(), false);
assertNotNull(pack);
assertNotNull(array);
assertNotNull(alpha);
assertTrue(length > 0);
return new PackedSymbolList(pack, array, length, alpha);
}
catch (IllegalAlphabetException iae) {
iae.printStackTrace();
return null;
}
}
};
// exercise the PackedSymbolList implementation
assertTrue(runRepeatedSymbolListTests(symListAlpha, symListAlpha, factory));
}
public void testSymbolListsEqual() throws Exception {
SymbolList dna = DNATools.createDNA("");
SymbolList rna = RNATools.createRNA("");
assertFalse(dna.equals(rna));
}
/**
* test for SimpleSymbolList that implements ambiguity symbols.
*/
public void testChunkedPackedSymbolListWithAmbiguitySymbols()
throws Exception
{
// create an alphabet with ambiguity symbols
FiniteAlphabet symListAlpha = (FiniteAlphabet) DNATools.getDNA();
FiniteAlphabet arrayAlpha = generateAmbiguousDNA();
assertNotNull(arrayAlpha);
assertNotNull(symListAlpha);
// create a SimpleSymbolList that supports ambiguity symbols
SymListFactory factory = new SymListFactory () {
public SymbolList createSymbolList(Symbol [] array, FiniteAlphabet alpha, int length)
{
assertNotNull(array);
assertNotNull(alpha);
assertTrue(length > 0);
try {
// create the factory that will make our sequence
ChunkedSymbolListFactory chunker = new ChunkedSymbolListFactory(new PackedSymbolListFactory(true));
// add symbols to it.
chunker.addSymbols(alpha, array, 0, length);
return chunker.makeSymbolList();
}
catch (IllegalAlphabetException iae) {
return null;
}
}
};
// exercise the PackedSymbolList implementation
assertTrue(runRepeatedSymbolListTests(arrayAlpha, symListAlpha, factory));
}
// creates a suite
public static Test suite()
{
TestSuite suite = new TestSuite(SymbolListTest.class);
// TestSuite suite = new TestSuite();
// suite.add(new SymbolListTest("PackedSymbolListWithAmbiguitySymbols"));
return suite;
}
// harness for tests
public static void main(String [] args)
{
junit.textui.TestRunner.run(suite());
}
}
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