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RPS-BLAST 2.2.4 [Aug-26-2002]
Query= gi|1786183|gb|AAC73113.1| (AE000111) aspartokinase I,
homoserine dehydrogenase I [Escherichia coli]
(820 letters)
Score E
Sequences producing significant alignments: (bits) Value
gnl|CDD|3919 smart00483, POLXc, DNA polymerase X family; include... 28 0.064
gnl|CDD|7379 smart00533, MUTSd, DNA-binding domain of DNA mismat... 26 0.47
gnl|CDD|178 smart00202, SR, Scavenger receptor Cys-rich; The sea... 22 4.5
gnl|CDD|8977 smart00359, PUA, Putative RNA-binding Domain in Pse... 22 7.0
gnl|CDD|7370 smart00486, POLBc, DNA polymerase type-B family; DN... 22 7.6
gnl|CDD|28 smart00035, CLa, CLUSTERIN alpha chain; 21 7.6
gnl|CDD|8994 smart00450, RHOD, Rhodanese Homology Domain; An alp... 22 8.0
>gnl|CDD|3919 smart00483, POLXc, DNA polymerase X family; includes vertebrate
polymerase beta and terminal
deoxynucleotidyltransferases
Length = 335
Score = 28.3 bits (63), Expect = 0.064
Identities = 11/57 (19%), Positives = 21/57 (36%), Gaps = 3/57 (5%)
Query: 599 SRRKFLYDTNVGAGLPVIENLQNLLNAGDELMKFSGILSGSLSYIFGKLDEGMSFSE 655
++RK Y V+++L +N+ +L GI I ++ G
Sbjct: 23 NKRKCSY---FRKAASVLKSLPFPINSMKDLKGLPGIGDKIKKKIEEIIETGKLSKA 76
>gnl|CDD|7379 smart00533, MUTSd, DNA-binding domain of DNA mismatch repair MUTS
family;
Length = 310
Score = 25.7 bits (56), Expect = 0.47
Identities = 19/107 (17%), Positives = 36/107 (32%), Gaps = 21/107 (19%)
Query: 9 TSVANAERFLR------VADILESNARQGQVATVLSAPAKITNHLVAMIEKTISGQDALP 62
+R LR + D+ E N R L+ E + L
Sbjct: 13 CKTPMGKRLLRRWLLQPLTDLKEINERL-----------DAVEELLENPELRQDLRGLLK 61
Query: 63 NISDAERIFAELLTGLAAAQPGFPLAQLKTFVDQEFAQIKHVLHGIS 109
I D ER+ + + A+ + L +L ++ +I+ +L +
Sbjct: 62 RIPDLERLLSRIKLSRASPR---DLLRLYDSLEG-LKEIRKLLESLE 104
>gnl|CDD|178 smart00202, SR, Scavenger receptor Cys-rich; The sea urchin egg
peptide speract contains 4 repeats of SR domains that
contain 6 conserved cysteines. May bind bacterial
antigens in the protein MARCO
Length = 101
Score = 22.2 bits (47), Expect = 4.5
Identities = 13/53 (24%), Positives = 20/53 (37%), Gaps = 2/53 (3%)
Query: 648 DEGMSFSEATTLAREMGYTEP--DPRDDLSGMDVARKLLILARETGRELELAD 698
D+G +A + R++G+ G L R TG E L+D
Sbjct: 27 DDGWDLRDANVVCRQLGFGGAVSASGSAYFGPGSGPIWLDNVRCTGTEASLSD 79
>gnl|CDD|8977 smart00359, PUA, Putative RNA-binding Domain in PseudoUridine
synthase and Archaeosine transglycosylase;
Length = 78
Score = 21.8 bits (46), Expect = 7.0
Identities = 10/40 (25%), Positives = 17/40 (42%), Gaps = 5/40 (12%)
Query: 135 AGVLEARGH-----NVTVIDPVEKLLAVGHYLESTVDIAE 169
GV+ G V ++D + L +G S+ +IA
Sbjct: 22 PGVVRVDGDIKEGDVVVIVDEKGEPLGIGLANMSSEEIAR 61
>gnl|CDD|7370 smart00486, POLBc, DNA polymerase type-B family; DNA polymerase
alpha, delta, epsilon and zeta chain (eukaryota), DNA
polymerases in archaea, DNA polymerase II in e. coli,
mitochondrial DNA polymerases and and virus DNA
polymerases
Length = 475
Score = 21.7 bits (45), Expect = 7.6
Identities = 8/33 (24%), Positives = 14/33 (42%), Gaps = 3/33 (9%)
Query: 247 KSMSYQEAMELSYFGAKVLHPRTI---TPIAQF 276
K + + ++ Y G KVL P+ P+
Sbjct: 275 KGLEPELKKKVKYEGGKVLEPKKGFYENPVLVL 307
>gnl|CDD|28 smart00035, CLa, CLUSTERIN alpha chain;
Length = 215
Score = 21.5 bits (45), Expect = 7.6
Identities = 7/13 (53%), Positives = 9/13 (68%)
Query: 479 ALLEQLKRQQSWL 491
+LLEQL Q W+
Sbjct: 129 SLLEQLNEQFGWV 141
>gnl|CDD|8994 smart00450, RHOD, Rhodanese Homology Domain; An alpha beta fold
found duplicated in the Rhodanese protein. The the
Cysteine containing enzymatically active version of the
domain is also found in the CDC25 class of protein
phosphatases and a variety of proteins such as sulfide
dehydrogenases and stress proteins such as Senesence
specific protein 1 in plants, PspE and GlpE in bacteria
and cyanide and arsenate resistance proteins. Inactive
versions with a loss of the cysteine are also seen in
Dual specificity phosphatases, ubiquitin hydrolases from
yeast and in sulfuryltransferases. These are likely to
play a role in protein interactions
Length = 109
Score = 21.7 bits (45), Expect = 8.0
Identities = 14/56 (25%), Positives = 17/56 (30%)
Query: 520 NWQEELAQAKEPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYADFLREGFHVV 575
E L + E +L + PVIV C S A GF V
Sbjct: 38 PLSELLDRRGETDSLFEELLGSLGLDKDKPVIVYCRSGNRSAKAAWLLRELGFKNV 93
Lambda K H
0.319 0.136 0.384
Gapped
Lambda K H
0.267 0.0574 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 1100, Extension: 100
Number of Hits to DB: 194,372
Number of Sequences: 0
Number of extensions: 14001
Number of successful extensions: 17
Number of sequences better than 10.0: 1
Number of HSP's better than 10.0 without gapping: 1
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 17
length of query: 438
length of database: 75,508
effective HSP length: 68
effective length of query: 438
effective length of database: 31,988
effective search space: 14010744
effective search space used: 24054976
T: 11
A: 40
X1: 1600 (737.2 bits)
X2: 3800 (1463.8 bits)
X3: 6400 (2465.3 bits)
S1: 4100 (1892.0 bits)
S2: 43 (20.7 bits)
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