1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
|
ID HSHNCPA1 standard; RNA; HUM; 1198 BP.
XX
AC X79536;
XX
SV X79536.1
XX
DT 03-JUN-1994 (Rel. 39, Created)
DT 03-JUN-1994 (Rel. 39, Last updated, Version 1)
XX
DE H.sapiens mRNA for hnRNPcore protein A1
XX
KW core protein.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria;
OC Primates; Catarrhini; Hominidae; Homo.
XX
RN [2]
RP 1-1198
RA Leffers H.;
RT ;
RL Submitted (01-JUN-1994) to the EMBL/GenBank/DDBJ databases.
RL H. Leffers, Inst. of Medical Research Biochemistry & Danish Centre for
RL Human Genome Research, Ole Worms Alle 170, Aarhus Univ., 8000 Aarhus C,
RL DENMARK
XX
RN [3]
RA Knudsen S.M., Leffers H.;
RT "Cloning and sequencing of a splice variant of human hnRNP core protein
RT A1";
RL Unpublished.
XX
DR SWISS-PROT; P09651; ROA1_HUMAN.
XX
FH Key Location/Qualifiers
FH
FT source 1..1198
FT /db_xref="taxon:9606"
FT /organism="Homo sapiens"
FT /tissue_type="lung"
FT /cell_type="fibroblast"
FT /cell_line="MRC5"
FT /clone_lib="lambda ZapII"
FT /clone="HDP1"
FT CDS 27..989
FT /db_xref="SWISS-PROT:P09651"
FT /product="hnRNPcore protein A1"
FT /protein_id="CAA56072.1"
FT /translation="MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVV
FT MRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTV
FT KKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV
FT IQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNF
FT SGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNF
FT GGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF"
FT misc_feature 995
FT /note="alternative splice site"
FT polyA_signal 1180..1185
XX
SQ Sequence 1198 BP; 334 A; 216 C; 336 G; 312 T; 0 other;
ttaaagtctc tcttcaccct gccgtcatgt ctaagtcaga gtctcctaaa gagcccgaac 60
agctgaggaa gctcttcatt ggagggttga gctttgaaac aactgatgag agcctgagga 120
gccattttga gcaatgggga acgctcacgg actgtgtggt aatgagagat ccaaacacca 180
agcgctctag gggctttggg tttgtcacat atgccactgt ggaggaggtg gatgcagcta 240
tgaatgcaag gccacacaag gtggatggaa gagttgtgga accaaagaga gctgtctcca 300
gagaagattc tcaaagacca ggtgcccact taactgtgaa aaagatattt gttggtggca 360
ttaaagaaga cactgaagaa catcacctaa gagattattt tgaacagtat ggaaaaattg 420
aagtgattga aatcatgact gaccgaggca gtggcaagaa aaggggcttt gcctttgtaa 480
cctttgacga ccatgactcc gtggataaga ttgtcattca gaaataccat actgtgaatg 540
gccacaactg tgaagttaga aaagccctgt caaagcaaga gatggctagt gcttcatcca 600
gccaaagagg tcgaagtggt tctggaaact ttggtggtgg tcgtggaggt ggtttcggtg 660
ggaatgacaa cttcggtcgt ggaggaaact tcagtggtcg tggtggcttt ggtggcagcc 720
gtggtggtgg tggatatggt ggcagtgggg atggctataa tggatttggc aatgatggaa 780
gcaattttgg aggtggtgga agctacaatg attttgggaa ttacaacaat cagtcttcaa 840
attttggacc catgaaggga ggaaattttg gaggcagaag ctctggcccc tatggcggtg 900
gaggccaata ctttgcaaaa ccacgaaacc aaggtggcta tggcggttcc agcagcagca 960
gtagctatgg cagtggcaga agattttaat tagggaggag tctgctacta gtcttatcag 1020
ctcttaaaaa cagaaactca tctgtccaag ttcgtggcag aaaggaacgt ccttgtgaag 1080
acctttatct gagccactgt acttcgttat cacgccatgc agtttacatg agctgttctg 1140
cagctcgaaa ttccattttg tgaatgggtt ttttttttta ataaactgta tttaactt 1198
//
ID HSHNRNPA standard; DNA; HUM; 5368 BP.
XX
AC X12671;
XX
SV X12671.1
XX
DT 23-NOV-1989 (Rel. 21, Created)
DT 24-APR-1993 (Rel. 35, Last updated, Version 3)
XX
DE Human gene for heterogeneous nuclear ribonucleoprotein (hnRNP) core
DE protein A1
XX
KW hnRNP A1 proten; ribonucleoprotein; RNA binding protein.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria;
OC Primates; Catarrhini; Hominidae; Homo.
XX
RN [1]
RP 1-5368
RA Riva S.;
RT ;
RL Submitted (23-AUG-1988) to the EMBL/GenBank/DDBJ databases.
RL Riva S., Consiglio Nazionale Delle Ricerche, Istituto Di Genetica
RL Biochimica Ed Evoluzionistica CNR, Via Abbiategrasso 2D7, 27100 Pavia,
RL Italy.
XX
RN [2]
RP 1-5368
RA Biamonti G., Buvoli M., Bassi M.T., Morandi C., Cobianchi F., Riva S.;
RT "Isolation of an active gene encoding human hnRNP protein A1";
RL J. Mol. Biol. 207:491-503(1988).
XX
DR SWISS-PROT; P09651; ROA1_HUMAN.
XX
FH Key Location/Qualifiers
FH
FT source 1..5368
FT /db_xref="taxon:9606"
FT /organism="Homo sapiens"
FT /clone="pES5"
FT /tissue_type="liver"
FT /clone_lib="lambdaCh4A."
FT mRNA join(695..813,1377..1493,1789..1935,2084..2294,2388..2480,
FT 2567..2659,2794..2868,3806..3961,4252..4311,4543..5240)
FT CDS join(799..813,1377..1493,1789..1935,2084..2294,2388..2480,
FT 2567..2659,2794..2868,3806..3961,4252..4307)
FT /db_xref="SWISS-PROT:P09651"
FT /product="hnrnp a1 protein"
FT /protein_id="CAA31191.1"
FT /translation="MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVV
FT MRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTV
FT KKIFVGGIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIV
FT IQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNF
FT SGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNF
FT GGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF"
FT exon 695..813
FT /number=1
FT misc_feature 695..695
FT /note="mRNA initiation site"
FT misc_feature 715..715
FT /note="mRNA initiation site"
FT misc_feature 735..735
FT /note="mRNA initiation site"
FT intron 814..1376
FT /number=1
FT exon 1377..1493
FT /number=2
FT intron 1494..1788
FT /number=2
FT exon 1789..1935
FT /number=3
FT intron 1936..2083
FT /number=3
FT exon 2084..2294
FT /number=4
FT intron 2295..2387
FT /number=4
FT exon 2388..2480
FT /number=5
FT intron 2481..2566
FT /number=5
FT exon 2567..2659
FT /number=6
FT intron 2660..2793
FT /number=6
FT exon 2794..2868
FT /number=7
FT intron 2869..3805
FT /number=7
FT exon 3806..3961
FT /number=8
FT intron 3962..4251
FT /number=8
FT exon 4252..4311
FT /number=9
FT intron 4312..4542
FT /number=9
FT exon 4543..5240
FT /number=10
XX
SQ Sequence 5368 BP; 1476 A; 1052 C; 1270 G; 1570 T; 0 other;
gggattgaga gtgatcactc acgctaacgt ctgccctgtt cctgtatggt gaggccgcac 60
cacaagccac caccgccgcc gccttctgcg caacgccaac cgcccgccaa aacggatcct 120
tccctgcgcc tgcgcaacca atcttgggac cggacctttt ttctccgccc actacgcatg 180
cgcaaagcta ggacaaactc ccgccaacac gcaggcgccg taggttcact gcctactcct 240
gcccgccatt tcacgtgttc tcagaggcag gtggaacttc ttaatgcgcc tgcgcaaaac 300
tcgccatttt actacacgtg cggtcaacaa gagttcattg caaaaaaatt gttacctcct 360
agctgcttgt ctaatacata gtgttaatca tgctttgcca agcgacttga ctgtaatatt 420
tgcgcgtgga agattaaaaa gatgttaaac acccaaggta gattcaaatg tgaatgattg 480
gtcggttggc caatcagact ggttaacaat aacattactc gggaaccaat ggactccaag 540
gggtggagac ggcgtagaac gaccgaagga atgacgttac acagcaatgt ggcaccacag 600
gccaatagca gggggaagcg atttcaagta tccaatcaga gctgttctag ggcggagtct 660
accaatgccg aaagcgagga ggcggggtaa aaaagagagg gcgaaggtag gctggcagat 720
acgttcgtca gcttgctcct ttctgcccgt ggacgccgcc gaagaagcat cgttaaagtc 780
tctcttcacc ctgccgtcat gtctaagtca gaggtgagtt aggcgcgctt tcccacttga 840
attttttcct ctccctttcc tgaatcggta agatgctgct gggtttcgtt ccttgcacca 900
gcccattcta cagttccttc ggtcgctgcc acggcctacc cctcccaaag ttcaagtcgc 960
cattttgtcc tcttgatcgc catgaggccg ctctccgcca accatgtgtt atcatgcggg 1020
actcgttact cgtagcaaaa ttcttaggca cacaggatct ttgtcttttt ttaaaccttg 1080
ccttggtgag cgagttttct aaagagcgat tagtcccatt gtggagatgc acccctaccg 1140
cccaagcctt tgttgcgcgt gcgtcggaag gcgactaggg acgcatgcgc ttgcgatttc 1200
ctagcactcc caactccagc atacggcctc ccttgatagg cagaagcacg tgtcttgttg 1260
cgacctgaac gaacaataag tgctaggtac acagttggtg tctagttttt cttttcctcg 1320
atggaaattg tttcgtgttg tagcccattt aacacttccc cctcccccca ctctagtctc 1380
ctaaagagcc cgaacagctg aggaagctct tcattggagg gttgagcttt gaaacaactg 1440
atgagagcct gaggagccat tttgagcaat ggggaacgct cacggactgt gtggtaagat 1500
ttggaaggga caaagcagta aaacagccga tttccttggc ttatcttggt gcagtcttct 1560
ccgaatgctt atgaaagtag ttaatagcat tatagttaga gctttgttgg caaaggaacg 1620
tcctgctttg attttaaaag ctaacctctt aaatctaagg gtagtgggaa actggacgaa 1680
ctttttataa aaggctggtg taaagtttcc tattgcccta ttcaaagtta aaataacaaa 1740
agcttttgcg gtcagacttt gtgttacata aattaacact gttctcaggt aatgagagat 1800
ccaaacacca agcgctctag gggctttggg tttgtcacat atgccactgt ggaggaggtg 1860
gatgcagcta tgaatgcaag gccacacaag gtggatggaa gagttgtgga accaaagaga 1920
gctgtctcca gagaagtgag tgggtttttt ttcttcttct tcttaaactt acttggatat 1980
gtgctgctat gaacttaaga ttcgggagtt ttctaaactt accaaaattt tttattcgag 2040
tataggcttt gctaatctaa acctatggtt tttctcctat taggattctc aaagaccagg 2100
tgcccactta actgtgaaaa agatatttgt tggtggcatt aaagaagaca ctgaagaaca 2160
tcacctaaga gattattttg aacagtatgg aaaaattgaa gtgattgaaa tcatgactga 2220
ccgaggcagt ggcaagaaaa ggggctttgc ctttgtaacc tttgacgacc atgactccgt 2280
ggataagatt gtcagtaagt atcagatagt ggcatttagt aagggttcca caatctgtat 2340
ggcattctaa accctgatac catgttgtat ctatgttttt tttttagttc agaaatacca 2400
tactgtgaat ggccacaact gtgaagttag aaaagccctg tcaaagcaag agatggctag 2460
tgcttcatcc agccaaagag gtatgcttgt tgcttaatta aaccttaaag gtaactttga 2520
gttactccag tatgaatgat ttaatgctta aacttcatgt cttaaggtcg aagtggttct 2580
ggaaactttg gtggtggtcg tggaggtggt ttcggtggga atgacaactt cggtcgtgga 2640
ggaaacttca gtggtcgtgg tatgtatggt ttatctacat gtagttctga cttctcacca 2700
tctttgctat gaagatttta cagtacggga actgcattca gaatgtcact ttaagtccaa 2760
gtcatactta aaacttgaaa ctttttctta caggtggctt tggtggcagc cgtggtggtg 2820
gtggatatgg tggcagtggg gatggctata atggatttgg caatgatggt aagtttttta 2880
ggaataagta gagaaaaatt cctggcaacc tggatcttta gaataggtta gtagagacta 2940
aaattctggt gcatgtcaaa ctcaactttg cccataacac gcatgctgtg agcaggcctt 3000
cagccgttac acttgcacaa gttttcattg tcaaatactt ttgtcttatt gagaagaatt 3060
gtattcttgt aggtggttat ggaggaggcg gccctggtta ctctggagga agcagaggct 3120
atggaagtgg tggacagggt tatggaaacc agggcagtgg ctatggcggg agtggcagct 3180
atgacagcta taacaacgga ggcggaggcg gctttggcgg tggtagtggt aggtatccag 3240
tgatccaagt acttggtgtg acagctagat tagcctttta gagcttgggt tctggtgctg 3300
ttgaagcatt gtgtggtaca ctgcatggta tattaaaaac aaatgggctt gctatgctac 3360
ctcctcctag ctttaagctg gggccgcctc actcccaaat agtagagata agtggatagt 3420
gttgtctttg agttagatta gtatcataga aggatttagt attttaactc ctttgggacc 3480
ttaggcgctt agttgatgta tccaagatac ttctgcttgc tgtggccctg gatccgtgaa 3540
ggccttcaag gctgaagggt atgcttgtgc cactctgaaa atctctttat tttatgtcat 3600
ggtgagttag gccagttttc tttgtattac tggattattc aactgaatgc ctttcccaga 3660
gaatgaaatg caaagattgg agtcaccata gtttgggaga aaggaaggct gataactcaa 3720
ccttatttta ttctgactgc taaacagaat tggaaactaa catcatcctc aggtaacaga 3780
taaaggccct ctttcccatt cataggaagc aattttggag gtggtggaag ctacaatgat 3840
tttgggaatt acaacaatca gtcttcaaat tttggaccca tgaagggagg aaattttgga 3900
ggcagaagct ctggccccta tggcggtgga ggccaatact ttgcaaaacc acgaaaccaa 3960
ggtatggtat ctatgtaatt ttggataatg tcaaaagagt gtctgtagct actgctggga 4020
agaaagccct ttaactgcta tgtctgggca gcaaaacgtt tatagtttag aaccttcaga 4080
aagtgataat ttgatcacaa attagaaaaa tcatgggacc tctttaccac ctcccttgta 4140
gtagggccat ttttaaatgg ccagacactt gaatttaact tttattatcc caaatatgaa 4200
aacattactg ttggcacttt gaaactttaa aagaaaaatt gtacttttca ggtggctatg 4260
gcggttccag cagcagcagt agctatggca gtggcagaag attttaatta ggtaagtaag 4320
cacctttttg tgtgttgaca taatttttta aattgctgat gaacccaata accctaatgt 4380
agctgagcag tgcaacatag ttaacattat aattgcagta attgtggata taaagttaat 4440
attcagatca gcaaaatttg tgggaaacaa acttgatatt ggattgtagc cttgagtctt 4500
aatatgttta gattaacaac tctattccat attgttcaac aggaaacaaa gcttagcagg 4560
agaggagagc cagagaagtg acagggaagc tacaggttac aacagatttg tgaactcagc 4620
caagcacagt ggtggcaggg cctagctgct acaaagaaga catgttttag acaaatactc 4680
atgtgtatgg gcaaaaaact cgaggactgt atttgtgact aattgtataa caggttattt 4740
tagtttctgt tctgtggaaa gtgtaaagca ttccaacaaa gggttttaat gtagattttt 4800
ttttttgcac cccatgctgt tgattgctaa atgtaacagt ctgatcgtga cgctgaataa 4860
atgtcttttt tttaatgtgc tgtgtaaagt tagtctactc ttaagccatc ttggtaaatt 4920
tccccaacag tgtgaagtta gaattccttc agggtgatgc caggttctat ttggaattta 4980
tatacaacct gcttgggtgg agaagccatt gtcttcggaa accttggtgt agttgaactg 5040
atagttactg ttgtgacctg aagttcacca ttaaaaggga ttacccaagc aaaatcatgg 5100
aatggttata aaagtgattg ttggcacatc ctatgcaata tatctaaatt gaataatggt 5160
accagataaa attatagatg ggaatgaagc ttgtgtatcc attatcatgt gtaatcaata 5220
aacgatttaa ttctcttgaa tgaaatgaca actgtatgga tttgggactg gcagagattt 5280
ggactttccc tacccactcc ccctgataat aatgttgaat gcttctatca caattcaagt 5340
tcaaagctct gctagggaat agaaacta 5368
//
ID HSRNPA1 standard; RNA; HUM; 1747 BP.
XX
AC X06747;
XX
SV X06747.1
XX
DT 08-JUN-1988 (Rel. 16, Created)
DT 12-SEP-1993 (Rel. 36, Last updated, Version 2)
XX
DE Human hnRNP core protein A1
XX
KW hnRNP A1 protein; ribonucleoprotein.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria;
OC Primates; Catarrhini; Hominidae; Homo.
XX
RN [1]
RP 1-1747
RA Riva S.;
RT ;
RL Submitted (26-JAN-1988) to the EMBL/GenBank/DDBJ databases.
RL Riva S., Istituto Di Genetica Biochimica, Ed Evoluzionistica - CNR, Via
RL Abbiategrasso 207, 27100 Pavia, Italy.
XX
RN [2]
RP 1-1747
RX MEDLINE; 88233978.
RA Buvoli M., Biamonti G., Ghetti A., Riva S., Bassi M.T., Horandi C.;
RT "cDNA cloning of human hnRNP protein A1 reveals the existence of multiple
RT mRNA isoforms.";
RL Nucleic Acids Res. 16:3751-3770(1988).
XX
DR SWISS-PROT; P09651; ROA1_HUMAN.
XX
CC pRP15 sequence encodes the protein A1 type alpha isoform,
CC pRP12 (truncated at the 5' end, respectively) the beta isoform
XX
FH Key Location/Qualifiers
FH
FT source 1..1747
FT /db_xref="taxon:9606"
FT /organism="Homo sapiens"
FT /tissue_type="fibroblast"
FT /clone_lib="lambdagt11"
FT /clone="pRP15"
FT CDS 86..1048
FT /db_xref="SWISS-PROT:P09651"
FT /note="protein A1-alpha (AA 1-320)"
FT /protein_id="CAA29922.1"
FT /translation="MSKSESPKEPEQLRKLFIGGLSFETTDESLRSHFEQWGTLTDCVV
FT MRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKVDGRVVEPKRAVSREDSQRPGAHLTV
FT KKIFVGGIKEDTEEHHLRDYFEQFGKIEVIEIMTDRGSGKKKGFAFVTFDDHDSVDKIV
FT IQKYHTVNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNF
FT SGRGGFGGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNF
FT GGRSSGPYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF"
FT misc_feature 209..209
FT /note="5' end of clone pRP12"
FT variation 467..469
FT /note="uau (Tyr) is uuu (Phe) in pRP12 (protein A1-beta)"
FT variation 521..523
FT /note="agg (Arg) is aag (Lys) in pRP12 (protein A1-beta)"
FT misc_feature 1365..1370
FT /note="polyA signal"
FT misc_feature 1726..1731
FT /note="polyA signal"
FT polyA_site 1747..1747
FT /note="polyA site"
XX
SQ Sequence 1747 BP; 512 A; 300 C; 466 G; 469 T; 0 other;
cgaaaggtta caaaggcaaa gccccttttc tgcccgtgga cgccgccgaa gaagcatcgt 60
taaagtctct cttcaccctg ccgtcatgtc taagtcagag tctcctaaag agcccgaaca 120
gctgaggaag ctcttcattg gagggttgag ctttgaaaca actgatgaga gcctgaggag 180
ccattttgag caatggggaa cgctcacgga ctgtgtggta atgagagatc caaacaccaa 240
gcgctctagg ggctttgggt ttgtcacata tgccactgtg gaggaggtgg atgcagctat 300
gaatgcaagg ccacacaagg tggatggaag agttgtggaa ccaaagagag ctgtctccag 360
agaagattct caaagaccag gtgcccactt aactgtgaaa aagatatttg ttggtggcat 420
taaagaagac actgaagaac atcacctaag agattatttt gaacagtttg gaaaaattga 480
agtgattgaa atcatgactg accgaggcag tggcaagaaa aagggctttg cctttgtaac 540
ctttgacgac catgactccg tggataagat tgtcattcag aaataccata ctgtgaatgg 600
ccacaactgt gaagttagaa aagccctgtc aaagcaagag atggctagtg cttcatccag 660
ccaaagaggt cgaagtggtt ctggaaactt tggtggtggt cgtggaggtg gtttcggtgg 720
gaatgacaac ttcggtcgtg gaggaaactt cagtggtcgt ggtggctttg gtggcagccg 780
tggtggtggt ggatatggtg gcagtgggga tggctataat ggatttggca atgatggaag 840
caattttgga ggtggtggaa gctacaatga ttttgggaat tacaacaatc agtcttcaaa 900
ttttggaccc atgaagggag gaaattttgg aggcagaagc tctggcccct atggcggtgg 960
aggccaatac tttgcaaaac cacgaaacca aggtggctat ggcggttcca gcagcagcag 1020
tagctatggc agtggcagaa gattttaatt aggaaacaaa gcttagcagg agaggagagc 1080
cagagaagtg acagggaagc tacaggttac aacagatttg tgaactcagc caagcacagt 1140
ggtggcaggg cctagctgct acaaagaaga catgttttag acaaatactc atgtgtatgg 1200
gcaaaaaact cgaggactgt atttgtgact aattgtataa caggttattt tagtttctgt 1260
tctgtggaaa gtgtaaagca ttccaacaaa gggttttaat gtagattttt tttttgcacc 1320
ccatgctgtt gattgctaaa tgtaacagtc tgatcgtgac gctgaataaa tgtctttttt 1380
ttaatgtgct gtgtaaagtt agtctactct taagccatct tggtaaattt ccccaacagt 1440
gtgaagttag aattccttca gggtgatgcc aggttctatt tggaatttat atacaacctg 1500
cttgggtgga gaagccattg tcttcggaaa ccttggtgta gttgaactga tagttactgt 1560
tgtgacctga agttcaccat taaaagggat tacccaagca aaatcatgga atggttataa 1620
aagtgattgt tggcacatcc tatgcaatat atctaaattg aataatggta ccagataaaa 1680
ttatagatgg gaatgaagct tgtgtatcca ttatcatgtg taatcaataa acgatttaat 1740
tctcttg 1747
//
ID HSUPIR1 standard; RNA; HUM; 924 BP.
XX
AC X04347;
XX
SV X04347.1
XX
DT 18-NOV-1986 (Rel. 10, Created)
DT 12-JUL-1995 (Rel. 44, Last updated, Version 3)
XX
DE Human liver mRNA fragment DNA binding protein UPI homologue
DE (C-terminus)
XX
KW DNA binding protein.
XX
OS Homo sapiens (human)
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Mammalia; Eutheria;
OC Primates; Catarrhini; Hominidae; Homo.
XX
RN [1]
RP 1-924
RX MEDLINE; 87053868.
RA Riva S., Morandi C., Tsoulfas P., Pandolfo M., Biamonti G., Merrill B.,
RA Williams K.R., Multhaup G., Beyreuther K., Werr H., Heinrich B.,
RA Schaefer K.P.;
RT "Mammalian single-stranded DNA binding protein UP I is derived from the
RT hnRNP cor protein A1";
RL EMBO J. 5:2267-2273(1986).
XX
DR SWISS-PROT; P09651; ROA1_HUMAN.
XX
CC Pos. 1-216 is homologous to UPI (aa 126-195); pos. 184-273 is
CC homologous to V8 protease peptide AI/II (aa 185-214)
XX
CC Data kindly reviewed (08-NOV-1986) by K. Beyreuther
XX
FH Key Location/Qualifiers
FH
FT source 1..924
FT /db_xref="taxon:9606"
FT /organism="Homo sapiens"
FT CDS <1..591
FT /codon_start=1
FT /db_xref="SWISS-PROT:P09651"
FT /note="ORF protein; C-terminal (aa 125-319; 196aa)"
FT /protein_id="CAA27874.1"
FT /translation="FEQYGKIEVIEIMTDPGSGKKRGFAFVTFDDHDSVDKIVIQKYHT
FT VNGHNCEVRKALSKQEMASASSSQRGRSGSGNFGGGRGGGFGGNDNFGRGGNFSGRGGF
FT GGSRGGGGYGGSGDGYNGFGNDGSNFGGGGSYNDFGNYNNQSSNFGPMKGGNFGGRSSG
FT PYGGGGQYFAKPRNQGGYGGSSSSSSYGSGRRF"
FT misc_feature 208..210
FT /note="dimethylated arginin"
FT polyA_signal 908..913
FT /note="pot. polyA signal"
FT polyA_site 924..924
FT /note="polyA site"
XX
SQ Sequence 924 BP; 262 A; 148 C; 266 G; 248 T; 0 other;
tttgaacagt atggaaaaat tgaagtgatt gaaatcatga ctgacccagg cagtggcaag 60
aaaaggggct ttgcctttgt aacctttgac gaccatgact ccgtggataa gattgtcatt 120
cagaaatacc atactgtgaa tggccacaac tgtgaagtta gaaaagccct gtcaaagcaa 180
gagatggcta gtgcttcatc cagccaaaga ggtcgaagtg gttctggaaa ctttggtggt 240
ggtcgtggag gtggtttcgg tgggaatgac aacttcggtc gtggaggaaa cttcagtggt 300
cgtggtggct ttggtggcag ccgtggtggt ggtggatatg gtggcagtgg ggatggctat 360
aatggatttg gcaatgatgg aagcaatttt ggaggtggtg gaagctacaa tgattttggg 420
aattacaaca atcagtcttc aaattttgga cccatgaagg gaggaaattt tggaggcaga 480
agctctggcc cctatggcgg tggaggccaa tactttgcaa aaccacgaaa ccaaggtggc 540
tatggcggtt ccagcagcag cagtagctat ggcagtggca gaagatttta attaggaaac 600
aagcttggca ggagaggaga gccagagaag tgacagggaa gctacaggtt acaacagatt 660
tgtgaactca gccaagcaca gtggtggcag ggcctagctg ctacaaagaa gacatgtttt 720
agacaaatac tcatgtgtat gggcaaaaaa ctcgaggact gtatttgtga ctaattgtat 780
aacaggttat tttagtttct gttctgtgga aagtgaaagc attccaacaa agggttttaa 840
tgtagatttt ttttttttgc accccatgct gttgattgct aaatgtaaca gtctgatcgt 900
gacgctgaat aaatgtcttt tttt 924
//
|
