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: Reference: Adams et al. 1982 - M-currents and other potassium currents in bullfrog sympathetic neurones
: Comment: corrected rates using q10 = 2.3, target temperature 34, orginal 21
NEURON {
SUFFIX Im
USEION k READ ek WRITE ik
RANGE gbar, g, ik
}
UNITS {
(S) = (siemens)
(mV) = (millivolt)
(mA) = (milliamp)
}
PARAMETER {
gbar = 0.00001 (S/cm2)
}
ASSIGNED {
v (mV)
ek (mV)
ik (mA/cm2)
g (S/cm2)
celsius (degC)
mInf
mTau
mAlpha
mBeta
}
STATE {
m
}
BREAKPOINT {
SOLVE states METHOD cnexp
g = gbar*m
ik = g*(v-ek)
}
DERIVATIVE states {
rates()
m' = (mInf-m)/mTau
}
INITIAL{
rates()
m = mInf
}
PROCEDURE rates(){
LOCAL qt
qt = 2.3^((celsius-21)/10)
UNITSOFF
mAlpha = 3.3e-3*exp(2.5*0.04*(v - -35))
mBeta = 3.3e-3*exp(-2.5*0.04*(v - -35))
mInf = mAlpha/(mAlpha + mBeta)
mTau = (1/(mAlpha + mBeta))/qt
UNITSON
}
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