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Metadata-Version: 2.1
Name: changeo
Version: 1.3.0
Summary: A bioinformatics toolkit for processing high-throughput lymphocyte receptor sequencing data.
Home-page: http://changeo.readthedocs.io
Download-URL: https://bitbucket.org/kleinstein/changeo/downloads
Author: Namita Gupta, Jason Anthony Vander Heiden
Author-email: immcantation@googlegroups.com
License: GNU Affero General Public License 3 (AGPL-3)
Keywords: bioinformatics,sequencing,immunology,adaptive immunity,immunoglobulin,AIRR-seq,Rep-Seq,B cell repertoire analysis,adaptive immune receptor repertoires
Classifier: Development Status :: 4 - Beta
Classifier: Environment :: Console
Classifier: Intended Audience :: Science/Research
Classifier: Natural Language :: English
Classifier: Operating System :: OS Independent
Classifier: Programming Language :: Python :: 3.4
Classifier: Topic :: Scientific/Engineering :: Bio-Informatics
License-File: LICENSE
.. image:: https://img.shields.io/pypi/dm/changeo
:target: https://pypi.org/project/changeo
.. image:: https://img.shields.io/static/v1?label=AIRR-C%20sw-tools%20v1&message=compliant&color=008AFF&labelColor=000000&style=plastic
:target: https://docs.airr-community.org/en/stable/swtools/airr_swtools_standard.html
Change-O - Repertoire clonal assignment toolkit
================================================================================
Change-O is a collection of tools for processing the output of V(D)J alignment
tools, assigning clonal clusters to immunoglobulin (Ig) sequences, and
reconstructing germline sequences.
Dramatic improvements in high-throughput sequencing technologies now enable
large-scale characterization of Ig repertoires, defined as the collection of
trans-membrane antigen-receptor proteins located on the surface of B cells and
T cells. Change-O is a suite of utilities to facilitate advanced analysis of
Ig and TCR sequences following germline segment assignment. Change-O
handles output from IMGT/HighV-QUEST and IgBLAST, and provides a wide variety of
clustering methods for assigning clonal groups to Ig sequences. Record sorting,
grouping, and various database manipulation operations are also included.
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