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Very brief installation instructions are provided in README.
For details, see the Installation and Configuration tutorial
http://www.circos.ca/documentation/tutorials/configuration/
For a guide for Mac OS X, see
http://zientzilaria.heroku.com/blog/2012/06/03/installing-circos-on-os-x/
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WINDOWS USERS
Please be attentive to the differences between UNIX and Windows, as
described in the above tutorial.
Be aware that UNIX commands will not work on Windows.
If you are unfamiliar with the DOS command-line, refer to this tutorial
http://www.bleepingcomputer.com/tutorials/tutorial76.html
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