File: coils-wrap.pod

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coils 2002-10
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=head1 NAME

coils-wrap - runs ncoils three times to give you a three-window output

=head1 SYNOPSIS

coils-wrap [OPTION]

=head1 DESCRIPTION

coils-wrap runs ncoils three times to give you a three-window output.

ncoils is a program that compares a sequence to a database of known parallel two-stranded coiled-coils and derives a similarity score. By comparing this score to the distribution of scores in globular and coiled-coil proteins, the program then calculates the probability that the sequence will adopt a coiled-coil conformation. 

=head1 OPTIONS

=over

=item -i

input file in FASTA format

=item -o

output file

=item -r

raw output file, default: `<output file>_raw'

=item -m

matrix type; set matrix (MTK or MTIDK)

=item -w

weight a&d = b,c,e,f&g (boolean)

=back

=head1 EXAMPLES

C<coils-wrap -m MTIDK -i /usr/share/doc/ncoils/1srya.fa -o /tmp/coils.out -r /tmp/coils_raw.txt && less /tmp/coils.out /tmp/coils_raw.txt>

C<ncoils -win 14 < /usr/share/doc/ncoils/1srya.fa>

=head1 FILES

=over

=item F</usr/share/coiledcoils/*.mat>

matrix data files

=back

=head1 AUTHOR

R.B. Russell, A.N. Lupas, 1999

=head1 COPYRIGHT AND LICENSE

GPL

Based on Lupas, Van Dyck & Stock (1991) Science 252,1162-1164

=head1 SEE ALSO

L<ncoils(1)>, L</usr/share/doc/coils/README>, L<http://www.russelllab.org/cgi-bin/coils/coils-svr.pl>

=over

=item A Lupas: Prediction and Analysis of Coiled-Coil Structures. Methods in Enzymology, 266, 513-525, 1996

=item A. Lupas, M. Van Dyke, and J. Stock: Predicting coiled coils from protein sequences. Science, 252, 1162-1164, 1991

=back