File: cph.s

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cph <- function(formula=formula(data),
                data=if(.R.)parent.frame() else sys.parent(),
                weights,
                subset,
                na.action=na.delete, 
                method=c("efron","breslow","exact",
                  "model.frame", "model.matrix"),
                singular.ok=FALSE,
                robust=FALSE,
                model=FALSE,
                x=FALSE,
                y=FALSE,
                se.fit=FALSE,
                eps=1e-4,
                init,
                iter.max=10,
                tol=1e-9,
                surv=FALSE,
                time.inc,
                type,
                vartype,
                conf.type,
                ...) {

  if(.R.)
    {
      require('survival')
      getN <- function(obj)
        {
          if(existsFunction(obj)) get(obj)
          else getFromNamespace(obj, 'survival')
        }
    }
  else getN <- function(obj) get(obj)
  
  method <- match.arg(method)
  call <- match.call()
  m <- match.call(expand=FALSE)
  m$na.action <- na.action
  m$method <- m$model <- m$x <- m$y <- m$... <- m$se.fit <-
    m$type <- m$vartype <-
      m$surv <- m$time.inc <- m$eps <- m$init <- m$iter.max <- m$tol <-
        m$weights <- m$singular.ok <- m$robust <- NULL

  m$na.action <- na.action

  if(.R.)
    m$drop.unused.levels <- TRUE
  
  m[[1]] <- as.name("model.frame")

  if (!inherits(formula,"formula")) {
    ## I allow a formula with no right hand side
    ## The dummy function stops an annoying warning message "Looking for
    ##  'formula' of mode function, ignored one of mode ..."
    if (inherits(formula,"Surv")) {
      xx <- function(x) formula(x)

      formula <- xx(paste(deparse(substitute(formula)), 1, sep="~"))
    }
    else
      stop("Invalid formula")
  }

  m$formula <- formula

  nstrata <- 0
  Strata <- NULL

  if(!missing(data) || (length(z <- attr(terms(formula, allowDotAsName=TRUE),"term.labels"))>0 &&
                        any(z!=".")))
    { #X's present
      if(.R.) {
        dul <- .Options$drop.unused.levels
        if(!length(dul) || dul) {
          on.exit(options(drop.unused.levels=dul))
          options(drop.unused.levels=FALSE)
        }
      }
      X <- Design(eval(m, if(.R.) parent.frame() else sys.parent()))
      atrx <- attributes(X)
      atr  <- atrx$Design
      nact <- atrx$na.action
      if(method=="model.frame")
        return(X)

      Terms <- if(missing(data))
        terms(formula, specials=c("strat","cluster"))
      else
        terms(formula, specials=c("strat","cluster"), data=data)

      asm   <- atr$assume.code
      name  <- atr$name

      cluster <- attr(Terms, "specials")$cluster
      stra    <- attr(Terms, "specials")$strat

      if(length(cluster))
        {
          if(missing(robust)) robust <- TRUE
          Terms <- Terms[-(cluster - 1)]
          cluster <- attr(X, 'cluster')
          attr(X, 'cluster') <- NULL
        }

      Terms.ns <- Terms
      if(length(stra))
        {
          temp <- untangle.specials(Terms.ns, "strat", 1)
          Terms.ns <- Terms.ns[-temp$terms]	#uses [.terms function
          ##  Set all factors=2
          ## (-> interaction effect not appearing in main effect
          ##  that was deleted strata effect)
          if(!.R.)
            {
              tfac <- attr(Terms,'factors')
              ## For some reason attr(...) <- pmin(attr(...)) changed a detail
              ## in factors attribute in R but doesn't seem to be needed in
              ## R or SV4 anyway
              if(length(tfac) && any(tfac > 1))
                attr(Terms,'factors') <- pmin(tfac, 1)
              
              tfac <- attr(Terms.ns,'factors')
              
              if(length(tfac) && any(tfac > 1))
                attr(Terms.ns,'factors') <-  pmin(tfac, 1)
            }
          
          Strata <- list()
          
          for(i in (1:length(asm))[asm==8])
            {
              nstrata <- nstrata+1
              xi <- X[[i+1]]
              levels(xi) <- paste(name[i],"=",levels(xi),sep="")
              Strata[[nstrata]] <- xi
            }

          names(Strata) <- paste("S",1:nstrata,sep="")
          Strata <- interaction(as.data.frame(Strata),drop=TRUE)
        }

      offs <- offset<- attr(Terms, "offset")
      
      xpres <- length(asm) && any(asm!=8)
      Y <- model.extract(X, 'response')
      if(!inherits(Y,"Surv"))
        stop("response variable should be a Surv object")
    
      weights <- model.extract(X, 'weights')
      tt <- length(offset)
      offset <- if(tt == 0) rep(0, nrow(Y))
      else if(tt == 1) X[[offset]]
      else {
        ff <- X[[offset[1]]]
        for(i in 2:tt)   # for case with multiple offset terms
          ff <- ff + X[[offset[i]]]
        ff
      }
    
      if(model)
        m <- X

      ##No mf if only strata factors
      if(!xpres)
        {
          X <- if(.R.) matrix(nrow=0,ncol=0)
          else NULL
          assign <- NULL
        }
      else
        {
          X <- model.matrix(Terms.ns, X)[,-1,drop=FALSE]
          assign <- attr(X, "assign")
          assign[[1]] <- NULL  # remove intercept position, renumber
        }
      
      nullmod <- FALSE
    }
  else {	# model with no right-hand side
    X <- NULL
    Terms <- terms(formula)
    yy <- attr(terms(formula),"variables")[1]
    Y <- eval(yy,data=data)
    if(!inherits(Y,"Surv"))
      stop("response variable should be a Surv object")
    
    Y <- Y[!is.na(Y)]
    assign <- NULL
    xpres <- FALSE
    nullmod <- TRUE
    nact <- NULL
  }

  ny <- ncol(Y)
  time.units <- attr(Y, "units")
  maxtime <- max(Y[,ny-1])

  rnam <- dimnames(Y)[[1]]
  if(xpres)
    dimnames(X) <- list(rnam, atr$colnames)

  if(method=="model.matrix")
    return(X)

  if(!length(time.units))
    time.units <- "Day"
  
  if(missing(time.inc)) {
    time.inc <- switch(time.units,
                       Day=30,
                       Month=1,
                       Year=1,
                       maxtime/10)
    
    if(time.inc>=maxtime | maxtime/time.inc>25)
      time.inc <- max(pretty(c(0,maxtime)))/10
  }

  if(nullmod)
    f <- NULL
  else {
    ytype <- attr(Y, "type")
    if( method=="breslow" || method =="efron") {
      if (ytype== 'right')
        fitter <- getN("coxph.fit")
      else if (ytype=='counting')
        fitter <- getN("agreg.fit")
      else
        stop(paste("Cox model doesn't support \"", ytype,
                   "\" survival data", sep=''))
    }
    else if (method=='exact')
      fitter <- getN("agexact.fit")
    else
      stop(paste ("Unknown method", method))

    if (missing(init))
      init <- NULL

    ## S-Plus 6 has control parameter.  S-Plus 5 has toler.chol.
    ## Previous to 5 has neither.  R has names(fitter)=NULL
    nf <- names(fitter)
    if(any(nf=='toler.chol'))
      f <- fitter(X, Y, strata=Strata, offset=offset, iter.max=iter.max,
                  eps=eps, weights=weights, init=init,
                  method=method, rownames=rnam, toler.chol=tol)
    else
      if(.R. || any(nf=='control'))
        f <- fitter(X, Y, strata=Strata, offset=offset,
                    weights=weights, init=init,
                    method=method, rownames=rnam,
                    control=getN('coxph.control')(eps=eps, toler.chol=tol,
                      toler.inf=1, iter.max=iter.max))
      else
        f <- fitter(X, Y, strata=Strata, offset=offset, iter.max=iter.max,
                    eps=eps, weights=weights, init=init,
                    method=method, rownames=rnam)
  }
  if (is.character(f)) {
    cat("Failure in cph:\n",f,"\n")
    if(.SV4.)
      return(structure(list(fail=TRUE,fitFunction='cph'),
                       class='Design'))
    else 
      return(structure(list(fail=TRUE),class="cph"))
  }
  else {
    if(length(f$coefficients) && any(is.na(f$coefficients))) {
      vars <- names(f$coefficients)[is.na(f$coefficients)]
      msg <- paste("X matrix deemed to be singular; variable",
                   paste(vars, collapse=" "))
      if(singular.ok)
        warning(msg)
      else {
        cat(msg,"\n")
        if(.SV4.)
          return(structure(list(fail=TRUE,fitFunction='cph'),
                           class='Design'))
        else
          return(structure(list(fail=TRUE),class="cph"))
      }
    }
  }
  f$terms <- Terms

  if(robust) {
    f$naive.var <- f$var
    ## Terry gets a little tricky here, calling resid before adding
    ## na.action method to avoid re-inserting NAs.  Also makes sure
    ## X and Y are there
    if(!length(cluster))
      cluster <- FALSE
    
    fit2 <- c(f, list(x=X, y=Y, method=method))
    if(length(stra))
      fit2$strata <- Strata
    
    temp <- getN('residuals.coxph')(fit2, type='dfbeta', collapse=cluster)
    f$var <- t(temp) %*% temp
  }
  
  if(length(weights) && any(weights!=1))
    f$weights <- weights

  nvar <- length(f$coefficients)

  temp <- factor(Y[,ny], levels=0:1, labels=c("No Event","Event"))
  n.table <- if(.R.) {
    if(!length(Strata))
      table(temp,dnn='Status')
    else
      table(Strata, temp, dnn=c('Stratum','Status'))
  }
  else {
    if(!length(Strata))
      table(temp)
    else
      table(Strata, temp)
  }

  f$n <- n.table
  nnn <- nrow(Y)
  nevent <- sum(Y[,ny])
  if(xpres)	{
    logtest <- -2 * (f$loglik[1] - f$loglik[2])
    R2.max <- 1 - exp(2*f$loglik[1]/nnn)
    R2 <- (1 - exp(-logtest/nnn))/R2.max
    P <- 1-pchisq(logtest,nvar)
    stats <- c(nnn, nevent, logtest, nvar, P, f$score, 
               1-pchisq(f$score,nvar), R2)
    names(stats) <- c("Obs", "Events", "Model L.R.", "d.f.", "P", 
                      "Score", "Score P","R2")
  }
  else {
    stats <- c(nnn, nevent)
    names(stats) <- c("Obs","Events")
  }

  f$method <- NULL
  if(xpres)
    dimnames(f$var) <- list(atr$colnames, atr$colnames)

  f <- c(f, list(call=call, Design=atr,
                 assign=DesignAssign(atr, 0, atrx$terms),
                 na.action=nact,
                 fail = FALSE, non.slopes = 0, stats = stats, method=method,
                 maxtime = maxtime, time.inc = time.inc,
                 units = time.units, fitFunction=c('cph','coxph')))

  if(xpres) {
    f$center <- sum(f$means*f$coefficients)
    f$scale.pred <- c("log Relative Hazard","Hazard Ratio")
    attr(f$linear.predictors,"strata") <- Strata
    names(f$linear.predictors) <- rnam
    if(se.fit) {
      XX <- X - rep(f$means,rep.int(nnn,nvar))   # see scale() function
      ##  XX <- sweep(X, 2, f$means)	# center   (slower)
      se.fit <- drop(((XX %*% f$var) * XX) %*% rep(1,ncol(XX)))^.5
      if(!.R.)
        storage.mode(se.fit) <- "single"
      
      names(se.fit) <- rnam
      f$se.fit <- se.fit  	
    }
  }
  if(model)
    f$model <- m
  
  if(nstrata > 0) {
    attr(X, "strata") <- attr(Y, "strata") <- Strata
    f$strata <- levels(Strata)
  }
  
  if(x) f$x <- X
  if(y) f$y <- Y

  if(is.character(surv) || surv) {
    if(!length(Strata))
      Strata <- rep(1, nnn)
    else
      Strata <- oldUnclass(Strata)
    
    nstr <- max(Strata, na.rm=TRUE)
    srv <- NULL
    tim <- NULL
    s.e. <- NULL
    timepts <- seq(0, maxtime, by=time.inc)
    s.sum <- array(if(.R.)
                     double(1)
                   else
                     single(1),
                   c(length(timepts),nstr,3),
                   list(format(timepts),paste("Stratum",1:nstr),
                        c("Survival","n.risk","std.err")))
    
    if(xpres) {
      g <- f; if(!x) g$x <- X; if(!y) g$y <- Y
      fname <- 'survfit.cph'
    } else {
      g <- f
      if(!y)
        g$y <- Y
      
      fname <- 'survfit.cph.null'
    }

    g <- list(g)

    if(!missing(type))
      g$type      <- type
    
    if(!missing(vartype))
      g$vartype   <- vartype
    
    if(!missing(conf.type))
      g$conf.type <- conf.type
    
    g <- do.call(fname, g)

    if(nstr==1)
      stemp <- rep(1, length(g$time))
    else
      stemp <- rep(1:nstr,g$strata)

    i <- 0
    for(k in 1:nstr) {
      j <- stemp==k; i <- i+1
      yy <- Y[Strata==i,ny-1]
      maxt <- max(yy)
      ##n.risk from surv.fit does not have usual meaning if not Kaplan-Meier
      
      tt <- c(0,g$time[j])
      su <- c(1,g$surv[j])
      se <- c(NA,-g$std.err[j]/logb(g$surv[j]))
      if(!.R.) {
        storage.mode(tt) <- 'single'
        storage.mode(su) <- 'single'
        storage.mode(se) <- 'single'
      }

      if(maxt>tt[length(tt)]) {
        tt <- c(tt, maxt)
        su <- c(su, su[length(su)])
        se <- c(se, NA)
      }

      kk <- 0
      for(tp in timepts) {
        kk <- kk + 1
        ##	  t.choice <- max((1:length(tt))[max(tt[tt<=tp])==tt])
        t.choice <- max((1:length(tt))[tt<=tp+1e-6])
        if(tp > max(tt)+1e-6 & su[length(su)]>0) {
          Su <- NA
          Se <- NA
        }
        else {
          Su <- su[t.choice]
          Se <- se[t.choice]
        }

        n.risk <- sum(yy>=tp)
        s.sum[kk,i,1:3] <- c(Su, n.risk, Se)
      }

      if(!is.character(surv)) {
        if(nstr==1)	{
          tim <- tt
          srv <- su
          s.e. <- se
        }
        else {
          tim <- c(tim, list(tt))
          srv <- c(srv, list(su))
          s.e. <- c(s.e., list(se))
        }
      }
    }

    if(is.character(surv))
      f$surv.summary <- s.sum
    else {
      attr(srv, "type") <- if(missing(type)) method
                           else type

      if(nstr>1) {
        names(srv) <- names(tim) <- names(s.e.) <- f$strata
      }

      f <- c(f, list(time=tim, surv=srv,
                     std.err=s.e., surv.summary=s.sum))		
    }
  }

  oldClass(f) <- if(.SV4.) 'Design'
                 else c("cph", "Design", "coxph")

  f
}

## Define a version of coxph.fit that works in S-Plus post version
## 4.5 as well as in earlier versions, as toler.chol argument was
## added in survival5 for S-Plus 2000 and Unix S-Plus 5.0
## coxphFit also handles the case where toler.chol and 4 other
## arguments were forgotten.  In S-Plus 6 control= is used.

if(.R. || .SV4.) {
  coxphFit <- function(..., method, strata=NULL, rownames=NULL, offset=NULL,
                       init=NULL, toler.chol=1e-9, eps=.0001, iter.max=10,
                       type) {

    if( method == "breslow" || method == "efron")
      {
        fitter <- if (type == 'right')
          getFromNamespace('coxph.fit', 'survival')
        else getFromNamespace('agreg.fit', 'survival')
    }
    else if (method == 'exact')
      fitter <- getFromNamespace('agexact.fit', 'survival')
    else stop("Unkown method ", method)

    if(!existsFunction('coxph.control'))
        coxph.control <- getFromNamespace('coxph.control', 'survival')

    res <- fitter(..., strata=strata, rownames=rownames,
                  offset=offset, init=init, method=method,
                  control=coxph.control(toler.chol=toler.chol, toler.inf=1,
                    eps=eps, iter.max=iter.max))

    if(is.character(res)) return(list(fail=TRUE))

    if(iter.max > 1 && res$iter >= iter.max)
      return(list(fail=TRUE))

    res$fail <- FALSE
    res
  }
} else {
  coxphFit <- function(..., strata=NULL, rownames=NULL, offset=NULL,
                     init=NULL, toler.chol=1e-9, eps=.0001, iter.max=10) {

    nf <- names(coxph.fit)
    res <-
      if(any(nf=='control'))
        {
          coxph.fit(..., strata=strata, rownames=rownames,
                    offset=offset, init=init,
                    control=coxph.control(toler.chol=toler.chol, toler.inf=1,
                      eps=eps, iter.max=iter.max))
        }
      else if(all(c('toler.chol', 'eps', 'iter.max') %in% nf))
        {
          coxph.fit(..., strata=strata, rownames=rownames,
                    offset=offset, init=init, toler.chol=toler.chol,
                    eps=eps, iter.max=iter.max)
        }
      else if(all(c('iter.max', 'eps') %in% nf))
        {
          coxph.fit(..., strata=strata, rownames=rownames,
                    offset=offset, init=init, eps=eps, iter.max=iter.max)
        }
      else coxph.fit(..., strata=strata, rownames=rownames,
                     offset=offset, init=init)

    if(is.character(res)) return(list(fail=TRUE))

    if(length(res$iter) && iter.max > 1 && res$iter >= iter.max)
      return(list(fail=TRUE))

    res$fail <- FALSE
    res
  }
}

Survival.cph <- function(object, ...) {
  if(!length(object$time) || !length(object$surv))
    stop("did not specify surv=T with cph")
  f <- function(times, lp=0, stratum=1, type=c("step","polygon"),
                time, surv) {
    type <- match.arg(type)
    if(length(stratum)>1) stop("does not handle vector stratum")
    if(length(times)==0) {
      if(length(lp)>1) stop("lp must be of length 1 if times=NULL")
      return(surv[[stratum]]^exp(lp))
    }
    s <- matrix(NA, nrow=length(lp), ncol=length(times),
                dimnames=list(names(lp), format(times)))
    if(is.list(time)) {time <- time[[stratum]]; surv <- surv[[stratum]]}
  if(type=="polygon")
    {
      if(length(lp)>1 && length(times)>1)
        stop('may not have length(lp)>1 & length(times>1) when type="polygon"')
      su <- approx(time, surv, times)$y
      return(su ^ exp(lp))
    }
  for(i in 1:length(times))
    {
      tm <- max((1:length(time))[time <= times[i]+1e-6])
      su <- surv[tm]
      if(times[i] > max(time)+1e-6) su <- NA
      s[,i] <- su^exp(lp)
    }
    drop(s)
  }
  formals(f) <- list(times=NULL, lp=0, stratum=1,
                     type=c("step","polygon"),
                     time=object$time, surv=object$surv)
  f
}

Quantile.cph <- function(object, ...) {
  if(!length(object$time) || !length(object$surv))
    stop("did not specify surv=T with cph")
  f <- function(q=.5, lp=0, stratum=1, type=c("step","polygon"), time, surv) {
    type <- match.arg(type)
    if(length(stratum)>1) stop("does not handle vector stratum")
    if(is.list(time)) {time <- time[[stratum]]; surv <- surv[[stratum]]}
    Q <- matrix(NA, nrow=length(lp), ncol=length(q),
                dimnames=list(names(lp), format(q)))
    for(j in 1:length(lp))
      {
        s <- surv^exp(lp[j])
        if(type=="polygon") Q[j,] <- approx(s, time, q)$y
        else for(i in 1:length(q))
          if(any(s <= q[i])) Q[j,i] <- min(time[s<=q[i]])  #is NA if none
      }
    drop(Q)
  }
  formals(f) <- list(q=.5, lp=0, stratum=1,
                     type=c('step','polygon'),
                     time=object$time, surv=object$surv)
  f
}


Mean.cph <- function(object, method=c("exact","approximate"),
                     type=c("step","polygon"), n=75, tmax, ...) {
  method <- match.arg(method)
  type   <- match.arg(type)

  if(!length(object$time) || !length(object$surv))
    stop("did not specify surv=T with cph")
  
  if(method=="exact")
    {
      f <- function(lp=0, stratum=1, type=c("step","polygon"),
                    tmax=NULL, time, surv)
        {
          type <- match.arg(type)
          if(length(stratum)>1) stop("does not handle vector stratum")
          if(is.list(time)) {time <- time[[stratum]]; surv <- surv[[stratum]]}
          Q <- lp
          if(!length(tmax))
            {
              if(min(surv)>1e-3)
                warning(paste("Computing mean when survival curve only defined down to",
                              format(min(surv)),"\n Mean is only a lower limit"))
              k <- rep(TRUE,length(time))
    }
          else
            {
              if(tmax>max(time)) stop(paste("tmax=",format(tmax),
                                            "> max follow-up time=",
                                            format(max(time))))
              k <- (1:length(time))[time<=tmax]
            }
          for(j in 1:length(lp))
            {
              s <- surv^exp(lp[j])
              Q[j] <- if(type=="step") sum(c(diff(time[k]),0) * s[k]) else 
              trap.rule(time[k], s[k])
            }
          Q
        }
      formals(f) <- alist(lp=0, stratum=1,
                          type=if(!missing(type))type else c("step","polygon"),
                          tmax=tmax,
                          time=object$time, surv=object$surv)
    }
  else
    {
      lp     <- object$linear.predictors
      lp.seq <- if(length(lp)) lp.seq <- seq(min(lp), max(lp), length=n) else 0
  
      time   <- object$time
      surv   <- object$surv
      nstrat <- if(is.list(time)) length(time) else 1
      areas  <- list()

      for(is in 1:nstrat)
        {
          tim <- if(nstrat==1) time else time[[is]]
          srv <- if(nstrat==1) surv else surv[[is]]
          if(!length(tmax))
            {
              if(min(srv)>1e-3)
                warning(paste("Computing mean when survival curve only defined down to",
                              format(min(srv)),
                              "\n Mean is only a lower limit"))
              k <- rep(TRUE,length(tim))
            }
          else
            {
              if(tmax>max(tim)) stop(paste("tmax=",format(tmax),
                                           "> max follow-up time=",
                                           format(max(tim))))
              k <- (1:length(tim))[tim<=tmax]
            }
          ymean <- lp.seq
          for(j in 1:length(lp.seq))
            {
              s <- srv^exp(lp.seq[j])
              ymean[j] <- if(type=="step") sum(c(diff(tim[k]),0) * s[k]) else 
              trap.rule(tim[k], s[k])
            }
          if(!.R.) storage.mode(ymean) <- "single"
          areas[[is]] <- ymean
        }
      if(nstrat>1) names(areas) <- names(time)

      f <- function(lp=0, stratum=1, lp.seq, areas)
        {

          if(length(stratum)>1) stop("does not handle vector stratum")
          area <- areas[[stratum]]
          if(length(lp.seq)==1 && all(lp==lp.seq))
            ymean <- rep(area,length(lp)) else
          ymean <- approx(lp.seq, area, xout=lp)$y
          if(any(is.na(ymean)))
            warning("means requested for linear predictor values outside range of linear\npredictor values in original fit")
          names(ymean) <- names(lp)
          ymean
        }
      if(!.R.) storage.mode(lp.seq) <- "single"
      formals(f) <- list(lp=0, stratum=1, lp.seq=lp.seq, areas=areas)
    }
  eval(f)
}

## cox.zph demands that the fit object inherit 'coxph'
## The following slightly changed cox.zph also explicitly invokes
## residuals.cph
if(.SV4.)
{
  cox.zph <- function(fit, transform = "km", global = TRUE) {
    call <- match.call()
    clas <- c(oldClass(fit), fit$fitFunction)  ##FEH
    if(!any(c('coxph','cph') %in% clas))       ##FEH
      stop("Argument must be the result of coxph or cph")
    if('coxph.null' %in% clas)               ##FEH + next 5
      stop("The are no score residuals for a Null model")
    sresid <- resid(fit, "schoenfeld")
    
    varnames <- names(fit$coef)
    nvar <- length(varnames)
    ndead <- length(sresid)/nvar
    if(nvar == 1)
      times <- as.numeric(names(sresid))
    else
      times <- as.numeric(dimnames(sresid)[[1]])

    if(is.character(transform))
      {
        tname <- transform
        ttimes <- switch(transform,
                         identity = times,
                         rank = rank(times),
                         log = log(times),
                         km = {
                           temp <- survfitKM(factor(rep(1, nrow(fit$y))),
                                              fit$y, se.fit = FALSE)
                           ## A nuisance to do left cont KM
                           t1 <- temp$surv[temp$n.event > 0]
                           t2 <- temp$n.event[temp$n.event > 0]
                           km <- rep(c(1, t1), c(t2, 0))
                           if(!length(attr(sresid, "strata")))
                             1 - km
                           else
                             (1 - km[sort.list(sort.list(times))])
                         },
                         stop("Unrecognized transform"))
      }
    else {
      tname <- deparse(substitute(transform))
      if(length(tname) > 1)
        tname <- "user"
      ttimes <- transform(times)
    }

    xx <- ttimes - mean(ttimes)
    r2 <- sresid %*% fit$var * ndead
    test <- xx %*% r2
    
    ## time weighted col sums
    corel <- c(cor(xx, r2))
    z <- c(test^2/(diag(fit$var) * ndead * sum(xx^2)))
    Z.ph <- cbind(corel, z, 1 - pchisq(z, 1))

    if(global && nvar > 1)
      {
        test <- c(xx %*% sresid)
        z <- (c(test %*% fit$var %*% test) * ndead)/sum(xx^2)
        Z.ph <- rbind(Z.ph, c(NA, z, 1 - pchisq(z, ncol(sresid))))
        dimnames(Z.ph) <- list(c(varnames, "GLOBAL"),
                               c("rho", "chisq", "p"))
      }
    else
      dimnames(Z.ph) <- list(varnames, c("rho", "chisq", "p"))

    dimnames(r2) <- list(times, names(fit$coef))
    temp <- list(table = Z.ph, x = ttimes,
                 y = r2 + outer(rep(1,ndead),fit$coef),
                 var = fit$var, call = call, transform = tname)

    oldClass(temp) <- "cox.zph"
    temp
  }
}

predict.cph <- function(object, newdata=NULL,
                        type=c("lp", "x", "data.frame", "terms", "adjto",
                          "adjto.data.frame", "model.frame"),
                        se.fit=FALSE, conf.int=FALSE,
                        conf.type=c('mean','individual'),
                        incl.non.slopes=NULL, non.slopes=NULL, kint=1,
                        na.action=na.keep, expand.na=TRUE,
                        center.terms=TRUE, ...) {
  predictDesign(object, newdata, type, se.fit, conf.int, conf.type,
                incl.non.slopes, non.slopes, kint,
                na.action, expand.na, center.terms, ...)
}