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Source: dindel
Maintainer: Debian Med Packaging Team <debian-med-packaging@lists.alioth.debian.org>
Uploaders: Animesh Sharma <sharma.animesh@gmail.com>,
Steffen Moeller <moeller@debian.org>,
Andreas Tille <tille@debian.org>
Section: science
Priority: optional
Build-Depends: debhelper (>= 9),
seqan-dev,
libbam-dev,
libboost-program-options-dev,
libboost-math-dev,
zlib1g-dev
Standards-Version: 3.9.8
Vcs-Browser: https://anonscm.debian.org/cgit/debian-med/dindel.git
Vcs-Git: https://anonscm.debian.org/git/debian-med/dindel.git
Homepage: https://sites.google.com/site/keesalbers/soft/dindel
Package: dindel
Architecture: any
Depends: ${shlibs:Depends},
${misc:Depends}
Description: determines indel calls from short-read data
Dindel is a program for calling small indels from short-read sequence
data ('next generation sequence data'). It currently is designed to
handle only Illumina data.
.
Dindel requires a BAM file containing the read-alignments as input. It
then extracts candidate indels from the BAM file, and realigns the reads
to candidate haplotypes consisting of these candidate indels. If there
is sufficient evidence for an alternative haplotype to the reference,
it will call an indel.
.
It is possible to test indels discovered with other methods using Dindel,
for instance longer indels obtained through assembly methods. Dindel
will then realign both mapped and unmapped reads to see if the candidate
indel is supported by the reads.
.
Dindel outputs both genotype likelihoods and includes a script to
convert these to a VCF file with indel and SNP calls.
.
There is basic support for outputting realigned BAM files for each
realignment-window. These realigned BAM files can be used to call SNPs
near (candidate) indels.
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