File: itkMultiMetricMultiResolutionImageRegistrationMethod.hxx

package info (click to toggle)
elastix 5.2.0-2
  • links: PTS, VCS
  • area: main
  • in suites: forky, sid, trixie
  • size: 42,480 kB
  • sloc: cpp: 68,403; lisp: 4,118; python: 1,013; xml: 182; sh: 177; makefile: 33
file content (610 lines) | stat: -rw-r--r-- 23,042 bytes parent folder | download
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
/*=========================================================================
 *
 *  Copyright UMC Utrecht and contributors
 *
 *  Licensed under the Apache License, Version 2.0 (the "License");
 *  you may not use this file except in compliance with the License.
 *  You may obtain a copy of the License at
 *
 *        http://www.apache.org/licenses/LICENSE-2.0.txt
 *
 *  Unless required by applicable law or agreed to in writing, software
 *  distributed under the License is distributed on an "AS IS" BASIS,
 *  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 *  See the License for the specific language governing permissions and
 *  limitations under the License.
 *
 *=========================================================================*/
#ifndef _itkMultiMetricMultiResolutionImageRegistrationMethod_hxx
#define _itkMultiMetricMultiResolutionImageRegistrationMethod_hxx

#include "itkMultiMetricMultiResolutionImageRegistrationMethod.h"

#include "itkContinuousIndex.h"
#include <vnl/vnl_math.h>

/** Macro that implements the set methods. */
#define itkImplementationSetMacro(_name, _type)                                                                        \
  template <typename TFixedImage, typename TMovingImage>                                                               \
  void MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::Set##_name(_type        _arg,     \
                                                                                                unsigned int pos)      \
  {                                                                                                                    \
    if (pos == 0)                                                                                                      \
    {                                                                                                                  \
      this->Superclass::Set##_name(_arg);                                                                              \
    }                                                                                                                  \
    if (pos >= this->GetNumberOf##_name##s())                                                                          \
    {                                                                                                                  \
      this->SetNumberOf##_name##s(pos + 1);                                                                            \
    }                                                                                                                  \
    if (this->m_##_name##s[pos] != _arg)                                                                               \
    {                                                                                                                  \
      this->m_##_name##s[pos] = _arg;                                                                                  \
      this->Modified();                                                                                                \
    }                                                                                                                  \
  } // comment to allow ; after calling macro

/** Macro that implements the get methods. */
#define itkImplementationGetMacro(_name, _type1, _type2)                                                               \
  template <typename TFixedImage, typename TMovingImage>                                                               \
  auto MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::Get##_name(unsigned int pos)      \
    const->_type1 _type2                                                                                               \
  {                                                                                                                    \
    if (pos >= this->GetNumberOf##_name##s())                                                                          \
    {                                                                                                                  \
      return 0;                                                                                                        \
    }                                                                                                                  \
    else                                                                                                               \
    {                                                                                                                  \
      return this->m_##_name##s[pos].GetPointer();                                                                     \
    }                                                                                                                  \
  } // comment to allow ; after calling macro

namespace itk
{

itkImplementationSetMacro(FixedImage, const FixedImageType *);
itkImplementationSetMacro(MovingImage, const MovingImageType *);
itkImplementationSetMacro(FixedImageRegion, const FixedImageRegionType);
itkImplementationSetMacro(Interpolator, InterpolatorType *);
itkImplementationSetMacro(FixedImagePyramid, FixedImagePyramidType *);
itkImplementationSetMacro(MovingImagePyramid, MovingImagePyramidType *);

itkImplementationGetMacro(FixedImage, const, FixedImageType *);
itkImplementationGetMacro(MovingImage, const, MovingImageType *);
itkImplementationGetMacro(Interpolator, , InterpolatorType *);
itkImplementationGetMacro(FixedImagePyramid, , FixedImagePyramidType *);
itkImplementationGetMacro(MovingImagePyramid, , MovingImagePyramidType *);


/**
 * ****************** Constructor ******************
 */

template <typename TFixedImage, typename TMovingImage>
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage,
                                                  TMovingImage>::MultiMetricMultiResolutionImageRegistrationMethod()
{
  this->SetMetric(CombinationMetricType::New());
  this->m_Stop = false;
  this->m_LastTransformParameters = ParametersType(1);
  this->m_LastTransformParameters.Fill(0.0f);

} // end Constructor


/**
 * **************** GetFixedImageRegion **********************************
 */

template <typename TFixedImage, typename TMovingImage>
auto
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::GetFixedImageRegion(
  unsigned int pos) const -> const FixedImageRegionType &
{
  if (pos >= this->GetNumberOfFixedImageRegions())
  {
    /** Return a dummy fixed image region. */
    return this->m_NullFixedImageRegion;
  }
  else
  {
    return this->m_FixedImageRegions[pos];
  }

} // end GetFixedImageRegion()


/**
 * ********************** SetMetric *******************************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::SetMetric(MetricType * _arg)
{
  CombinationMetricType * testPtr = dynamic_cast<CombinationMetricType *>(_arg);
  if (testPtr)
  {
    if (this->m_CombinationMetric != testPtr)
    {
      this->m_CombinationMetric = testPtr;
      this->Superclass::SetMetric(this->m_CombinationMetric);
      this->Modified();
    }
  }
  else
  {
    itkExceptionMacro("The metric must of type CombinationImageToImageMetric!");
  }

} // end SetMetric()


/**
 * ****************** Initialize *******************************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::Initialize()
{
  this->CheckOnInitialize();

  /** Setup the metric. */
  this->GetCombinationMetric()->SetTransform(this->GetModifiableTransform());

  this->GetCombinationMetric()->SetFixedImage(this->GetFixedImagePyramid()->GetOutput(this->GetCurrentLevel()));
  for (unsigned int i = 0; i < this->GetNumberOfFixedImagePyramids(); ++i)
  {
    this->GetCombinationMetric()->SetFixedImage(this->GetFixedImagePyramid(i)->GetOutput(this->GetCurrentLevel()), i);
  }

  this->GetCombinationMetric()->SetMovingImage(this->GetMovingImagePyramid()->GetOutput(this->GetCurrentLevel()));
  for (unsigned int i = 0; i < this->GetNumberOfMovingImagePyramids(); ++i)
  {
    this->GetCombinationMetric()->SetMovingImage(this->GetMovingImagePyramid(i)->GetOutput(this->GetCurrentLevel()), i);
  }

  this->GetCombinationMetric()->SetInterpolator(this->GetInterpolator());
  for (unsigned int i = 0; i < this->GetNumberOfInterpolators(); ++i)
  {
    this->GetCombinationMetric()->SetInterpolator(this->GetInterpolator(i), i);
  }

  this->GetCombinationMetric()->SetFixedImageRegion(this->m_FixedImageRegionPyramids[0][this->GetCurrentLevel()]);
  for (unsigned int i = 0; i < this->m_FixedImageRegionPyramids.size(); ++i)
  {
    this->GetCombinationMetric()->SetFixedImageRegion(this->m_FixedImageRegionPyramids[i][this->GetCurrentLevel()], i);
  }

  // this->GetMetric()->Initialize();
  this->GetCombinationMetric()->Initialize();

  /** Setup the optimizer. */
  this->GetModifiableOptimizer()->SetCostFunction(this->GetModifiableMetric());
  this->GetModifiableOptimizer()->SetInitialPosition(this->GetInitialTransformParametersOfNextLevel());

  /** Connect the transform to the Decorator. */
  TransformOutputType * transformOutput = static_cast<TransformOutputType *>(this->ProcessObject::GetOutput(0));

  transformOutput->Set(this->GetTransform());

} // end Initialize()


/**
 * ****************** PrepareAllPyramids ******************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::PrepareAllPyramids()
{
  this->CheckPyramids();

  /** Set up the fixed image pyramids and the fixed image region pyramids. */
  using SizeType = typename FixedImageRegionType::SizeType;
  using IndexType = typename FixedImageRegionType::IndexType;
  using ScheduleType = typename FixedImagePyramidType::ScheduleType;

  this->m_FixedImageRegionPyramids.resize(this->GetNumberOfFixedImagePyramids());
  for (unsigned int i = 0; i < this->GetNumberOfFixedImagePyramids(); ++i)
  {
    // Setup the fixed image pyramid
    FixedImagePyramidPointer fixpyr = this->GetFixedImagePyramid(i);
    if (fixpyr.IsNotNull())
    {
      fixpyr->SetNumberOfLevels(this->GetNumberOfLevels());
      if (this->GetNumberOfFixedImages() > 1)
      {
        fixpyr->SetInput(this->GetFixedImage(i));
      }
      else
      {
        fixpyr->SetInput(this->GetFixedImage());
      }
      fixpyr->UpdateLargestPossibleRegion();

      ScheduleType schedule = fixpyr->GetSchedule();

      FixedImageRegionType fixedImageRegion;
      if (this->GetNumberOfFixedImageRegions() > 1)
      {
        fixedImageRegion = this->GetFixedImageRegion(i);
      }
      else
      {
        fixedImageRegion = this->GetFixedImageRegion();
      }
      SizeType  inputSize = fixedImageRegion.GetSize();
      IndexType inputStart = fixedImageRegion.GetIndex();
      IndexType inputEnd = inputStart;
      for (unsigned int dim = 0; dim < TFixedImage::ImageDimension; ++dim)
      {
        inputEnd[dim] += (inputSize[dim] - 1);
      }

      this->m_FixedImageRegionPyramids[i].reserve(this->GetNumberOfLevels());
      this->m_FixedImageRegionPyramids[i].resize(this->GetNumberOfLevels());

      // Compute the FixedImageRegion corresponding to each level of the
      // pyramid.
      //
      // In the ITK implementation this uses the same algorithm of the ShrinkImageFilter
      // since the regions should be compatible. However, we inherited another
      // Multiresolution pyramid, which does not use the same shrinking pattern.
      // Instead of copying the shrinking code, we compute image regions from
      // the result of the fixed image pyramid.
      using PointType = typename FixedImageType::PointType;
      using CoordRepType = typename PointType::CoordRepType;

      PointType inputStartPoint;
      PointType inputEndPoint;
      fixpyr->GetInput()->TransformIndexToPhysicalPoint(inputStart, inputStartPoint);
      fixpyr->GetInput()->TransformIndexToPhysicalPoint(inputEnd, inputEndPoint);

      for (unsigned int level = 0; level < this->GetNumberOfLevels(); ++level)
      {
        SizeType         size;
        IndexType        start;
        FixedImageType * fixedImageAtLevel = fixpyr->GetOutput(level);
        /** map the original fixed image region to the image resulting from the
         * FixedImagePyramid at level l.
         * To be on the safe side, the start point is ceiled, and the end point
         * is floored. To see why, consider an image of 4 by 4, and its
         * downsampled version of 2 by 2.
         */
        const auto startcindex =
          fixedImageAtLevel->template TransformPhysicalPointToContinuousIndex<CoordRepType>(inputStartPoint);
        const auto endcindex =
          fixedImageAtLevel->template TransformPhysicalPointToContinuousIndex<CoordRepType>(inputEndPoint);
        for (unsigned int dim = 0; dim < TFixedImage::ImageDimension; ++dim)
        {
          start[dim] = static_cast<IndexValueType>(std::ceil(startcindex[dim]));
          size[dim] = std::max(
            NumericTraits<SizeValueType>::One,
            static_cast<SizeValueType>(static_cast<SizeValueType>(std::floor(endcindex[dim])) - start[dim] + 1));
        }

        this->m_FixedImageRegionPyramids[i][level].SetSize(size);
        this->m_FixedImageRegionPyramids[i][level].SetIndex(start);

      } // end for loop over res levels

    } // end if fixpyr!=0

  } // end for loop over fixed pyramids

  /** Setup the moving image pyramids. */
  for (unsigned int i = 0; i < this->GetNumberOfMovingImagePyramids(); ++i)
  {
    MovingImagePyramidPointer movpyr = this->GetMovingImagePyramid(i);
    if (movpyr.IsNotNull())
    {
      movpyr->SetNumberOfLevels(this->GetNumberOfLevels());
      if (this->GetNumberOfMovingImages() > 1)
      {
        movpyr->SetInput(this->GetMovingImage(i));
      }
      else
      {
        movpyr->SetInput(this->GetMovingImage());
      }
      movpyr->UpdateLargestPossibleRegion();
    }
  }

} // end PrepareAllPyramids()


/**
 * ****************** PrintSelf ******************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::PrintSelf(std::ostream & os,
                                                                                        Indent         indent) const
{
  Superclass::PrintSelf(os, indent);

} // end PrintSelf()


/**
 * ********************* GenerateData ***********************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::GenerateData()
{
  this->m_Stop = false;

  /** Check the transform and set the initial parameters. */
  if (this->GetTransform() == nullptr)
  {
    itkExceptionMacro("Transform is not present");
  }

  this->SetInitialTransformParametersOfNextLevel(this->GetInitialTransformParameters());

  if (this->GetInitialTransformParametersOfNextLevel().Size() != this->GetTransform()->GetNumberOfParameters())
  {
    itkExceptionMacro("Size mismatch between initial parameter and transform");
  }

  /** Prepare the fixed and moving pyramids. */
  this->PrepareAllPyramids();

  /** Loop over the resolution levels. */
  for (unsigned int currentLevel = 0; currentLevel < this->GetNumberOfLevels(); ++currentLevel)
  {
    this->SetCurrentLevel(currentLevel);

    // Invoke an iteration event.
    // This allows a UI to reset any of the components between
    // resolution level.
    this->InvokeEvent(IterationEvent());

    // Check if there has been a stop request
    if (this->m_Stop)
    {
      break;
    }

    try
    {
      // initialize the interconnects between components
      this->Initialize();
    }
    catch (const ExceptionObject &)
    {
      this->m_LastTransformParameters = ParametersType(1);
      this->m_LastTransformParameters.Fill(0.0f);

      // pass exception to caller
      throw;
    }

    try
    {
      // do the optimization
      this->GetModifiableOptimizer()->StartOptimization();
    }
    catch (const ExceptionObject &)
    {
      // An error has occurred in the optimization.
      // Update the parameters
      this->m_LastTransformParameters = this->GetOptimizer()->GetCurrentPosition();

      // Pass exception to caller
      throw;
    }

    // get the results
    this->m_LastTransformParameters = this->GetOptimizer()->GetCurrentPosition();
    this->GetModifiableTransform()->SetParameters(this->m_LastTransformParameters);

    // setup the initial parameters for next level
    if (this->GetCurrentLevel() < this->GetNumberOfLevels() - 1)
    {
      this->SetInitialTransformParametersOfNextLevel(this->m_LastTransformParameters);
    }

  } // end for loop over res levels

} // end GenerateData()


/**
 * ***************** GetMTime ******************
 */

template <typename TFixedImage, typename TMovingImage>
ModifiedTimeType
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::GetMTime() const
{
  ModifiedTimeType mtime = Superclass::GetMTime();
  ModifiedTimeType m;

  // Some of the following should be removed once ivars are put in the
  // input and output lists

  for (unsigned int i = 0; i < this->GetNumberOfInterpolators(); ++i)
  {
    InterpolatorPointer interpolator = this->GetInterpolator(i);
    if (interpolator)
    {
      m = interpolator->GetMTime();
      mtime = (m > mtime ? m : mtime);
    }
  }

  for (unsigned int i = 0; i < this->GetNumberOfFixedImages(); ++i)
  {
    FixedImageConstPointer fixedImage = this->GetFixedImage(i);
    if (fixedImage)
    {
      m = fixedImage->GetMTime();
      mtime = (m > mtime ? m : mtime);
    }
  }

  for (unsigned int i = 0; i < this->GetNumberOfMovingImages(); ++i)
  {
    MovingImageConstPointer movingImage = this->GetMovingImage(i);
    if (movingImage)
    {
      m = movingImage->GetMTime();
      mtime = (m > mtime ? m : mtime);
    }
  }

  for (unsigned int i = 0; i < this->GetNumberOfFixedImagePyramids(); ++i)
  {
    FixedImagePyramidPointer fixedImagePyramid = this->GetFixedImagePyramid(i);
    if (fixedImagePyramid)
    {
      m = fixedImagePyramid->GetMTime();
      mtime = (m > mtime ? m : mtime);
    }
  }

  for (unsigned int i = 0; i < this->GetNumberOfMovingImagePyramids(); ++i)
  {
    MovingImagePyramidPointer movingImagePyramid = this->GetMovingImagePyramid(i);
    if (movingImagePyramid)
    {
      m = movingImagePyramid->GetMTime();
      mtime = (m > mtime ? m : mtime);
    }
  }

  return mtime;

} // end GetMTime()


/**
 * ****************** CheckPyramids ******************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::CheckPyramids()
{
  /** Check if at least one of the following are provided. */
  if (this->GetFixedImage() == nullptr)
  {
    itkExceptionMacro("FixedImage is not present");
  }
  if (this->GetMovingImage() == nullptr)
  {
    itkExceptionMacro("MovingImage is not present");
  }
  if (this->GetFixedImagePyramid() == nullptr)
  {
    itkExceptionMacro("Fixed image pyramid is not present");
  }
  if (this->GetMovingImagePyramid() == nullptr)
  {
    itkExceptionMacro("Moving image pyramid is not present");
  }

  /** Check if the number if fixed/moving pyramids >= nr of fixed/moving images,
   * and whether the number of fixed image regions == the number of fixed images.
   */
  if (this->GetNumberOfFixedImagePyramids() < this->GetNumberOfFixedImages())
  {
    itkExceptionMacro("The number of fixed image pyramids should be >= the number of fixed images");
  }
  if (this->GetNumberOfMovingImagePyramids() < this->GetNumberOfMovingImages())
  {
    itkExceptionMacro("The number of moving image pyramids should be >= the number of moving images");
  }
  if (this->GetNumberOfFixedImageRegions() != this->GetNumberOfFixedImages())
  {
    itkExceptionMacro("The number of fixed image regions should equal the number of fixed images");
  }

} // end CheckPyramids()


/**
 * ****************** CheckOnInitialize ******************
 */

template <typename TFixedImage, typename TMovingImage>
void
MultiMetricMultiResolutionImageRegistrationMethod<TFixedImage, TMovingImage>::CheckOnInitialize()
{
  /** Check if at least one of the following is present. */
  if (this->GetMetric() == nullptr)
  {
    itkExceptionMacro("Metric is not present");
  }
  if (this->GetOptimizer() == nullptr)
  {
    itkExceptionMacro("Optimizer is not present");
  }
  if (this->GetTransform() == nullptr)
  {
    itkExceptionMacro("Transform is not present");
  }
  if (this->GetInterpolator() == nullptr)
  {
    itkExceptionMacro("Interpolator is not present");
  }

  /** nrofmetrics >= nrofinterpolators >= nrofpyramids >= nofimages */
  unsigned int nrOfMetrics = this->GetCombinationMetric()->GetNumberOfMetrics();
  if (this->GetNumberOfInterpolators() > nrOfMetrics)
  {
    itkExceptionMacro("NumberOfInterpolators can not exceed the NumberOfMetrics in the CombinationMetric!");
  }
  if (this->GetNumberOfFixedImagePyramids() > nrOfMetrics)
  {
    itkExceptionMacro("NumberOfFixedImagePyramids can not exceed the NumberOfMetrics in the CombinationMetric!");
  }
  if (this->GetNumberOfMovingImagePyramids() > nrOfMetrics)
  {
    itkExceptionMacro("NumberOfMovingImagePyramids can not exceed the NumberOfMetrics in the CombinationMetric!");
  }
  if (this->GetNumberOfMovingImagePyramids() > this->GetNumberOfInterpolators())
  {
    itkExceptionMacro("NumberOfMovingImagePyramids can not exceed the NumberOfInterpolators!");
  }

  /** For all components: ==nrofmetrics of ==1. */
  if ((this->GetNumberOfInterpolators() != 1) && (this->GetNumberOfInterpolators() != nrOfMetrics))
  {
    itkExceptionMacro("The NumberOfInterpolators should equal 1 or equal the NumberOfMetrics");
  }
  if ((this->GetNumberOfFixedImagePyramids() != 1) && (this->GetNumberOfFixedImagePyramids() != nrOfMetrics))
  {
    itkExceptionMacro("The NumberOfFixedImagePyramids should equal 1 or equal the NumberOfMetrics");
  }
  if ((this->GetNumberOfMovingImagePyramids() != 1) && (this->GetNumberOfMovingImagePyramids() != nrOfMetrics))
  {
    itkExceptionMacro("The NumberOfMovingImagePyramids should equal 1 or equal the NumberOfMetrics");
  }
  if ((this->GetNumberOfFixedImages() != 1) && (this->GetNumberOfFixedImages() != nrOfMetrics))
  {
    itkExceptionMacro("The NumberOfFixedImages should equal 1 or equal the NumberOfMetrics");
  }
  if ((this->GetNumberOfMovingImages() != 1) && (this->GetNumberOfMovingImages() != nrOfMetrics))
  {
    itkExceptionMacro("The NumberOfMovingImages should equal 1 or equal the NumberOfMetrics");
  }

} // end CheckOnInitialize()


} // end namespace itk

#undef itkImplementationSetMacro
#undef itkImplementationGetMacro

#endif