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/* RAxML-VI-HPC (version 2.2) a program for sequential and parallel estimation of phylogenetic trees
* Copyright August 2006 by Alexandros Stamatakis
*
* Partially derived from
* fastDNAml, a program for estimation of phylogenetic trees from sequences by Gary J. Olsen
*
* and
*
* Programs of the PHYLIP package by Joe Felsenstein.
*
* This program is free software; you may redistribute it and/or modify its
* under the terms of the GNU General Public License as published by the Free
* Software Foundation; either version 2 of the License, or (at your option)
* any later version.
*
* This program is distributed in the hope that it will be useful, but
* WITHOUT ANY WARRANTY; without even the implied warranty of MERCHANTABILITY
* or FITNESS FOR A PARTICULAR PURPOSE. See the GNU General Public License
* for more details.
*
*
* For any other enquiries send an Email to Alexandros Stamatakis
* Alexandros.Stamatakis@epfl.ch
*
* When publishing work that is based on the results from RAxML-VI-HPC please cite:
*
* Alexandros Stamatakis:"RAxML-VI-HPC: maximum likelihood-based phylogenetic analyses with thousands of taxa and mixed models".
* Bioinformatics 2006; doi: 10.1093/bioinformatics/btl446
*/
#ifdef _USE_ZLIB
#include <zlib.h>
#endif
#ifdef _FINE_GRAIN_MPI
int processes;
double *globalResult;
#endif
int processID;
infoList iList;
FILE *INFILE;
#ifdef _USE_ZLIB
gzFile byteFile;
#else
FILE *byteFile;
#endif
char run_id[128] = "",
seq_file[1024] = "",
weightFileName[1024] = "",
modelFileName[1024] = "",
byteFileName[1024] = "",
infoFileName[1024] = "",
secondaryStructureFileName[1024] = "",
excludeFileName[1024],
proteinModelFileName[1024];
char *protModels[NUM_PROT_MODELS] = {"DAYHOFF", "DCMUT", "JTT", "MTREV", "WAG", "RTREV", "CPREV", "VT", "BLOSUM62", "MTMAM", "LG", "MTART", "MTZOA", "PMB",
"HIVB", "HIVW", "JTTDCMUT", "FLU", "STMTREV", "AUTO", "LG4M", "LG4X", "GTR"};
const char inverseMeaningBINARY[4] = {'_', '0', '1', '-'};
const char inverseMeaningDNA[16] = {'_', 'A', 'C', 'M', 'G', 'R', 'S', 'V', 'T', 'W', 'Y', 'H', 'K', 'D', 'B', '-'};
const char inverseMeaningPROT[23] = {'A','R', 'N', 'D', 'C', 'Q', 'E', 'G', 'H', 'I', 'L', 'K', 'M', 'F', 'P', 'S',
'T', 'W', 'Y', 'V', 'B', 'Z', '-'};
const char inverseMeaningGeneric32[33] = {'0', '1', '2', '3', '4', '5', '6', '7',
'8', '9', 'A', 'B', 'C', 'D', 'E', 'F',
'G', 'H', 'I', 'J', 'K', 'L', 'M', 'N',
'O', 'P', 'Q', 'R', 'S', 'T', 'U', 'V',
'-'};
const char inverseMeaningGeneric64[33] = {'0', '1', '2', '3', '4', '5', '6', '7',
'8', '9', 'A', 'B', 'C', 'D', 'E', 'F',
'G', 'H', 'I', 'J', 'K', 'L', 'M', 'N',
'O', 'P', 'Q', 'R', 'S', 'T', 'U', 'V',
'-'};
const unsigned int bitVectorIdentity[256] = {0 ,1 ,2 ,3 ,4 ,5 ,6 ,7 ,8 ,9 ,10 ,11 ,12 ,13 ,14 ,15 ,16 ,17 ,18 ,19 ,20 ,21 ,22 ,23 ,24 ,25 ,26 ,
27 ,28 ,29 ,30 ,31 ,32 ,33 ,34 ,35 ,36 ,37 ,38 ,39 ,40 ,41 ,42 ,43 ,44 ,45 ,46 ,47 ,48 ,49 ,50 ,51 ,
52 ,53 ,54 ,55 ,56 ,57 ,58 ,59 ,60 ,61 ,62 ,63 ,64 ,65 ,66 ,67 ,68 ,69 ,70 ,71 ,72 ,73 ,74 ,75 ,76 ,
77 ,78 ,79 ,80 ,81 ,82 ,83 ,84 ,85 ,86 ,87 ,88 ,89 ,90 ,91 ,92 ,93 ,94 ,95 ,96 ,97 ,98 ,99 ,100 ,101 ,
102 ,103 ,104 ,105 ,106 ,107 ,108 ,109 ,110 ,111 ,112 ,113 ,114 ,115 ,116 ,117 ,118 ,119 ,120 ,121 ,122 ,
123 ,124 ,125 ,126 ,127 ,128 ,129 ,130 ,131 ,132 ,133 ,134 ,135 ,136 ,137 ,138 ,139 ,140 ,141 ,142 ,143 ,
144 ,145 ,146 ,147 ,148 ,149 ,150 ,151 ,152 ,153 ,154 ,155 ,156 ,157 ,158 ,159 ,160 ,161 ,162 ,163 ,164 ,
165 ,166 ,167 ,168 ,169 ,170 ,171 ,172 ,173 ,174 ,175 ,176 ,177 ,178 ,179 ,180 ,181 ,182 ,183 ,184 ,185 ,
186 ,187 ,188 ,189 ,190 ,191 ,192 ,193 ,194 ,195 ,196 ,197 ,198 ,199 ,200 ,201 ,202 ,203 ,204 ,205 ,206 ,
207 ,208 ,209 ,210 ,211 ,212 ,213 ,214 ,215 ,216 ,217 ,218 ,219 ,220 ,221 ,222 ,223 ,224 ,225 ,226 ,227 ,
228 ,229 ,230 ,231 ,232 ,233 ,234 ,235 ,236 ,237 ,238 ,239 ,240 ,241 ,242 ,243 ,244 ,245 ,246 ,247 ,248 ,
249 ,250 ,251 ,252 ,253 ,254 ,255};
const unsigned int bitVectorAA[23] = {1, 2, 4, 8, 16, 32, 64, 128,
256, 512, 1024, 2048, 4096,
8192, 16384, 32768, 65536, 131072, 262144,
524288, 12 /* N | D */, 96 /*Q | E*/, 1048575 /* - */};
const unsigned int bitVectorSecondary[256] = {0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 0, 1, 2, 3, 4, 5, 6, 7, 8, 9,
10, 11, 12, 13, 14, 15, 0, 16, 32, 48, 64, 80, 96, 112, 128, 144, 160, 176, 192,
208, 224, 240, 0, 17, 34, 51, 68, 85, 102, 119, 136, 153, 170, 187, 204, 221, 238,
255, 0, 256, 512, 768, 1024, 1280, 1536, 1792, 2048, 2304, 2560, 2816, 3072, 3328,
3584, 3840, 0, 257, 514, 771, 1028, 1285, 1542, 1799, 2056, 2313, 2570, 2827, 3084,
3341, 3598, 3855, 0, 272, 544, 816, 1088, 1360, 1632, 1904, 2176, 2448, 2720, 2992,
3264, 3536, 3808, 4080, 0, 273, 546, 819, 1092, 1365, 1638, 1911, 2184, 2457, 2730,
3003, 3276, 3549, 3822, 4095, 0, 4096, 8192, 12288, 16384, 20480, 24576, 28672, 32768,
36864, 40960, 45056, 49152, 53248, 57344, 61440, 0, 4097, 8194, 12291, 16388, 20485, 24582,
28679, 32776, 36873, 40970, 45067, 49164, 53261, 57358, 61455, 0, 4112, 8224, 12336, 16448,
20560, 24672, 28784, 32896, 37008, 41120, 45232, 49344, 53456, 57568, 61680, 0, 4113, 8226,
12339, 16452, 20565, 24678, 28791, 32904, 37017, 41130, 45243, 49356, 53469, 57582, 61695,
0, 4352, 8704, 13056, 17408, 21760, 26112, 30464, 34816, 39168, 43520, 47872, 52224, 56576,
60928, 65280, 0, 4353, 8706, 13059, 17412, 21765, 26118, 30471, 34824, 39177, 43530, 47883,
52236, 56589, 60942, 65295, 0, 4368, 8736, 13104, 17472, 21840, 26208, 30576, 34944, 39312,
43680, 48048, 52416, 56784, 61152, 65520, 0, 4369, 8738, 13107, 17476, 21845, 26214, 30583,
34952, 39321, 43690, 48059, 52428, 56797, 61166, 65535};
const unsigned int bitVector32[33] = {1, 2, 4, 8, 16, 32, 64, 128,
256, 512, 1024, 2048, 4096, 8192, 16384, 32768,
65536, 131072, 262144, 524288, 1048576, 2097152, 4194304, 8388608,
16777216, 33554432, 67108864, 134217728, 268435456, 536870912, 1073741824, 2147483648u,
4294967295u};
/*const unsigned int bitVector64[65] = {};*/
const unsigned int mask32[32] = {1, 2, 4, 8, 16, 32, 64, 128, 256, 512, 1024, 2048, 4096, 8192, 16384, 32768, 65536, 131072,
262144, 524288, 1048576, 2097152, 4194304, 8388608, 16777216, 33554432, 67108864, 134217728,
268435456, 536870912, 1073741824, 2147483648U};
const char *secondaryModelList[21] = { "S6A (GTR)", "S6B", "S6C", "S6D", "S6E", "S7A (GTR)", "S7B", "S7C", "S7D", "S7E", "S7F", "S16 (GTR)", "S16A", "S16B", "S16C",
"S16D", "S16E", "S16F", "S16I", "S16J", "S16K"};
double masterTime;
double accumulatedTime;
int partCount = 0;
int optimizeRateCategoryInvocations = 1;
partitionLengths pLengths[MAX_MODEL] = {
/* BINARY */
// {4, 4, 2, 4, 2, 1, 2, 8, 2, 2, FALSE, FALSE, 3, inverseMeaningBINARY, 2, FALSE, bitVectorIdentity},
//eiLength changed from 2 -> 4
{4, 4, 2, 4, 4, 1, 2, 8, 2, 2, FALSE, FALSE, 3, inverseMeaningBINARY, 2, FALSE, bitVectorIdentity},
/* DNA */
{16, 16, 4, 16, 16, 6, 4, 64, 6, 4, FALSE, FALSE, 15, inverseMeaningDNA, 4, FALSE, bitVectorIdentity},
/* AA */
{400, 400, 20, 400, 400, 190, 20, 460, 190, 20, FALSE, FALSE, 22, inverseMeaningPROT, 20, TRUE, bitVectorAA},
/* SECONDARY_DATA */
{256, 256, 16, 256, 256, 120, 16, 4096, 120, 16, FALSE, FALSE, 255, (char*)NULL, 16, TRUE, bitVectorSecondary},
/* SECONDARY_DATA_6 */
{36, 36, 6, 36, 36, 15, 6, 384, 15, 6, FALSE, FALSE, 63, (char*)NULL, 6, TRUE, bitVectorIdentity},
/* SECONDARY_DATA_7 */
{49, 49, 7, 49, 49, 21, 7, 896, 21, 7, FALSE, FALSE, 127, (char*)NULL, 7, TRUE, bitVectorIdentity},
/* 32 states */
{1024, 1024, 32, 1024, 1024, 496, 32, 1056, 496, 32, FALSE, FALSE, 32, inverseMeaningGeneric32, 32, TRUE, bitVector32},
/* 64 states */
{4096, 4096, 64, 4096, 4096, 2016, 64, 4160, 64, 2016, FALSE, FALSE, 64, (char*)NULL, 64, TRUE, (unsigned int*)NULL}
};
partitionLengths pLength;
#ifdef _USE_PTHREADS
volatile int NumberOfJobs;
volatile int jobCycle = 0;
volatile int threadJob = 0;
volatile int NumberOfThreads;
volatile double *reductionBuffer;
volatile double *reductionBufferTwo;
volatile char *barrierBuffer;
#endif
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