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Guide to sequence and alignment files:
.fasta file is the unaligned sequences
.reference.{mfa,stock} is the reference alignment
.{mfa,stock} is the alignment produced by FSA run with the options
--noindel2 (for only 1 set of indel states)
--refinement 0 (for no iterative refinement)
Origins of sequence and alignment files in example/:
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BRalibaseII:
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tRNA.aln1
U5.aln1
References:
1. Gardner PP, Wilm A & Washietl S (2005) A benchmark of multiple sequence alignment programs upon structural RNAs. Nucleic Acids Research. 33(8):2433-2439.Supp. Mat.
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Balibase:
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RV12.BBS12030
References:
1. Thompson JD, Plewniak F, Poch O. BAliBASE: a benchmark alignment database for the evaluation of multiple alignment programs.
Bioinformatics. 1999 Jan;15(1):87-8.
2. Thompson JD, Plewniak F, Poch O. A comprehensive comparison of multiple sequence alignment programs.
Nucleic Acids Res. 1999 Jul 1;27(13):2682-90
3. Bahr A, Thompson JD, Thierry JC, Poch O. BAliBASE (Benchmark Alignment dataBASE): enhancements for repeats, transmembrane sequences and circular permutations.
Nucleic Acids Res. 2001 Jan 1;29(1):323-6.
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