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Source: hhsuite
Maintainer: Debian Med Packaging Team <debian-med-packaging@lists.alioth.debian.org>
Uploaders: Laszlo Kajan <lkajan@debian.org>,
Andreas Tille <tille@debian.org>,
Sascha Steinbiss <satta@debian.org>
Section: science
Priority: optional
Build-Depends: debhelper-compat (= 13),
libsimde-dev,
cmake,
imagemagick,
help2man
Standards-Version: 4.6.1
Vcs-Browser: https://salsa.debian.org/med-team/hhsuite
Vcs-Git: https://salsa.debian.org/med-team/hhsuite.git
Homepage: https://toolkit.tuebingen.mpg.de/
Rules-Requires-Root: no
Package: hhsuite
Architecture: any
Depends: ${shlibs:Depends},
${misc:Depends},
${perl:Depends},
hhsuite-data (= ${source:Version}),
python3
Conflicts: ffindex
Built-Using: ${simde:Built-Using}
Description: sensitive protein sequence searching based on HMM-HMM alignment
HH-suite is an open-source software package for sensitive protein sequence
searching based on the pairwise alignment of hidden Markov models (HMMs).
.
This package contains HHsearch and HHblits among other programs and utilities.
.
HHsearch takes as input a multiple sequence alignment (MSA) or profile HMM
and searches a database of HMMs (e.g. PDB, Pfam, or InterPro) for homologous
proteins. HHsearch is often used for protein structure prediction to detect
homologous templates and to build highly accurate query-template pairwise
alignments for homology modeling.
.
HHblits can build high-quality MSAs starting from single sequences or from
MSAs. It transforms these into a query HMM and, using an iterative search
strategy, adds significantly similar sequences from the previous search to
the updated query HMM for the next search iteration. Compared to PSI-BLAST,
HHblits is faster, up to twice as sensitive and produces more accurate
alignments.
Package: hhsuite-data
Architecture: all
Multi-Arch: foreign
Depends: ${misc:Depends}
Description: sensitive protein sequence searching based on HMM-HMM alignment (data)
HH-suite is an open-source software package for sensitive protein sequence
searching based on the pairwise alignment of hidden Markov models (HMMs).
.
This package contains architecture independent scripts and data files.
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