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/*
* Copyright 2018, Chanhee Park <parkchanhee@gmail.com> and Daehwan Kim <infphilo@gmail.com>
*
* This file is part of HISAT 2.
*
* HISAT 2 is free software: you can redistribute it and/or modify
* it under the terms of the GNU General Public License as published by
* the Free Software Foundation, either version 3 of the License, or
* (at your option) any later version.
*
* HISAT 2 is distributed in the hope that it will be useful,
* but WITHOUT ANY WARRANTY; without even the implied warranty of
* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
* GNU General Public License for more details.
*
* You should have received a copy of the GNU General Public License
* along with HISAT 2. If not, see <http://www.gnu.org/licenses/>.
*/
#include <stdarg.h>
#include <Python.h>
#include "ht2.h"
#define HT2_HANDLE_ID "handle"
#ifdef DEBUG
#define DEBUGLOG(fmt, ...) do { fprintf(stderr, "%s:%d:%s(): " fmt, __FILE__, __LINE__, __func__, ##__VA_ARGS__); } while(0)
#else
#define DEBUGLOG(fmt, ...)
#endif
static ht2_handle_t get_handle(PyObject *cap)
{
return PyCapsule_GetPointer(cap, HT2_HANDLE_ID);
}
static PyObject *conv_refnames_result(struct ht2_index_getrefnames_result *result)
{
PyObject *refnames = NULL;
size_t i = 0;
if(result == NULL) {
return NULL;
}
refnames = PyList_New(result->count);
for(i = 0; i < result->count; i++) {
PyObject *str = PyString_FromString(result->names[i]);
PyList_SetItem(refnames, i, str);
}
return refnames;
}
static PyObject *conv_repeat_expand_result(struct ht2_repeat_expand_result *result)
{
PyObject *positions = NULL;
size_t i = 0;
if(result == NULL) {
return NULL;
}
positions = PyList_New(result->count);
for(i = 0; i < result->count; i++) {
struct ht2_position *htpos = &result->positions[i];
PyList_SetItem(positions, i,
Py_BuildValue("(III)", htpos->chr_id, htpos->direction, htpos->pos)
);
}
return positions;
}
static PyObject *conv_ht2opt(ht2_option_t *opts)
{
PyObject *py_opt = NULL;
py_opt = PyDict_New();
if(py_opt == NULL) {
return NULL;
}
#define HT2_OPT_BUILD(_pobj, _popt, _name, _type) \
do {\
if(PyDict_SetItemString((_pobj), #_name, Py_BuildValue((_type), (_popt)->_name)) < 0) {\
DEBUGLOG("Can't set item %s\n", #_name);\
} \
} while(0)
HT2_OPT_BUILD(py_opt, opts, offRate, "i");
HT2_OPT_BUILD(py_opt, opts, useMm, "i");
HT2_OPT_BUILD(py_opt, opts, useShmem, "i");
HT2_OPT_BUILD(py_opt, opts, mmSweep, "i");
HT2_OPT_BUILD(py_opt, opts, noRefNames, "i");
HT2_OPT_BUILD(py_opt, opts, noSplicedAlignment, "i");
HT2_OPT_BUILD(py_opt, opts, gVerbose, "i");
HT2_OPT_BUILD(py_opt, opts, startVerbose, "i");
HT2_OPT_BUILD(py_opt, opts, sanityCheck, "i");
HT2_OPT_BUILD(py_opt, opts, useHaplotype, "i");
return py_opt;
}
static void update_ht2_options(ht2_option_t *ht2opt, PyObject *py_opt)
{
#define HT2_OPT_UPDATE(_pobj, _ht2opt, _name) \
do {\
PyObject *p;\
if((p = PyDict_GetItemString((_pobj), #_name)) != NULL) { \
(_ht2opt)->_name = PyInt_AsLong(p); \
DEBUGLOG(#_name " %d\n", (ht2opt)->_name); \
if(PyErr_Occurred() != NULL) { \
DEBUGLOG("Error Occurred"); \
}\
}\
} while (0)
HT2_OPT_UPDATE(py_opt, ht2opt, offRate);
HT2_OPT_UPDATE(py_opt, ht2opt, useMm);
HT2_OPT_UPDATE(py_opt, ht2opt, mmSweep);
HT2_OPT_UPDATE(py_opt, ht2opt, noRefNames);
HT2_OPT_UPDATE(py_opt, ht2opt, noSplicedAlignment);
HT2_OPT_UPDATE(py_opt, ht2opt, gVerbose);
HT2_OPT_UPDATE(py_opt, ht2opt, startVerbose);
HT2_OPT_UPDATE(py_opt, ht2opt, sanityCheck);
HT2_OPT_UPDATE(py_opt, ht2opt, useHaplotype);
}
static PyObject *ht2py_get_options(PyObject *self, PyObject *args)
{
ht2_option_t ht2opt;
ht2_init_options(&ht2opt);
/* convert ht2_option_t to PyObject(map) */
PyObject *pobj = conv_ht2opt(&ht2opt);
return pobj;
}
static PyObject *ht2py_init(PyObject *self, PyObject *args)
{
ht2_handle_t handle;
PyObject *popt = NULL;
char *name = NULL;
if(!PyArg_ParseTuple(args, "sO", &name, &popt)) {
return NULL;
}
DEBUGLOG("name %s\n", name);
DEBUGLOG("popt %p\n", popt);
if(!PyDict_CheckExact(popt)) {
// TODO
// exception
DEBUGLOG("Invalid data type\n");
return NULL;
}
ht2_option_t ht2opt;
ht2_init_options(&ht2opt);
update_ht2_options(&ht2opt, popt);
handle = ht2_init(name, &ht2opt);
DEBUGLOG("handle %p\n", handle);
PyObject *cap = PyCapsule_New(handle, HT2_HANDLE_ID, NULL);
return cap;
}
static PyObject *ht2py_close(PyObject *self, PyObject *args)
{
ht2_handle_t handle;
PyObject *cap;
// Parse Args
// ht2py.close(handle)
//
if(!PyArg_ParseTuple(args, "O", &cap)) {
DEBUGLOG("Can't parse args\n");
return NULL;
}
handle = get_handle(cap);
if(handle == NULL) {
DEBUGLOG("Can't get handle\n");
return NULL;
}
DEBUGLOG("handle %p\n", handle);
ht2_close(handle);
Py_RETURN_NONE;
}
static PyObject *ht2py_index_getrefnamebyid(PyObject *self, PyObject *args)
{
PyObject *cap;
uint32_t chr_id;
// ht2py.index_getrefnamebyid(handle, chr_id)
if(!PyArg_ParseTuple(args, "Oi", &cap, &chr_id)) {
DEBUGLOG("Can't parse args\n");
return NULL;
}
ht2_handle_t handle = get_handle(cap);
if(handle == NULL) {
DEBUGLOG("Can't get handle\n");
return NULL;
}
const char *refname = ht2_index_getrefnamebyid(handle, chr_id);
if(refname == NULL) {
DEBUGLOG("Can't get refname(%u)\n", chr_id);
return Py_BuildValue("s", "");
}
return Py_BuildValue("s", refname);
}
static PyObject *ht2py_index_getrefnames(PyObject *self, PyObject *args)
{
ht2_handle_t handle;
PyObject *cap;
// Parse Args
// ht2py.index_getrefnames(handle)
if(!PyArg_ParseTuple(args, "O", &cap)) {
DEBUGLOG("Can't parse args\n");
return NULL;
}
handle = get_handle(cap);
if(handle == NULL) {
DEBUGLOG("Can't get handle\n");
return NULL;
}
struct ht2_index_getrefnames_result *result = NULL;
ht2_error_t ret = ht2_index_getrefnames(handle, &result);
PyObject *refnames = NULL;
if(ret == HT2_OK) {
/* Build List of names */
refnames = conv_refnames_result(result);
free(result);
} else {
refnames = PyList_New(0);
}
return refnames;
}
static PyObject *ht2py_repeat_expand(PyObject *self, PyObject *args)
{
PyObject *cap;
char *name = NULL;
uint64_t rpos = 0;
uint64_t rlen = 0;
// Parse Args
// ht2py.repeat_expand(handle, 'repeat_name', repeat_pos, repeat_len)
if(!PyArg_ParseTuple(args, "OsLL", &cap, &name, &rpos, &rlen)) {
DEBUGLOG("Can't parse args\n");
return NULL;
}
//fprintf(stderr, "%s, %lu, %lu\n", name, rpos, rlen);
ht2_handle_t handle = get_handle(cap);
if(handle == NULL) {
DEBUGLOG("Can't get handle\n");
return NULL;
}
struct ht2_repeat_expand_result *result = NULL;
ht2_error_t ret = ht2_repeat_expand(handle, name, rpos, rlen, &result);
PyObject *positions = NULL;
if(ret == HT2_OK) {
/* Build list of position */
positions = conv_repeat_expand_result(result);
free(result);
} else {
DEBUGLOG("error %d, %s, %lu, %lu\n", ret,
name, rpos, rlen);
positions = PyList_New(0);
}
return positions;
}
static PyMethodDef myMethods[] = {
/* Initialize APIs */
{"get_options", ht2py_get_options, METH_NOARGS, "Get default options"},
{"init", ht2py_init, METH_VARARGS, "Initialize HT2Lib handle"},
{"close", ht2py_close, METH_VARARGS, "Release HT2Lib handle"},
/* Index APIs */
{"index_getrefnamebyid", ht2py_index_getrefnamebyid, METH_VARARGS, "Get reference name"},
{"index_getrefnames", ht2py_index_getrefnames, METH_VARARGS, "Get all reference names"},
/* Repeat APIs */
{"repeat_expand", ht2py_repeat_expand, METH_VARARGS, "Find reference positions"},
/* */
{NULL, NULL, 0, NULL}
};
PyMODINIT_FUNC
initht2py(void)
{
(void)Py_InitModule("ht2py", myMethods);
}
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