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|
# STOCKHOLM 1.0
#=GF ID fn3
#=GF AC PF00041.13
#=GF DE Fibronectin type III domain
#=GF AU Sonnhammer ELL
#=GF GA 8.0 7.2
#=GF NC 7.9 7.9
#=GF TC 8.0 7.2
#=GF SE Swissprot_feature_table
#=GF TP Domain
#=GF BM hmmbuild -FHMM_ls.ann SEED.ann
#=GF BM hmmcalibrate --seed 0 HMM_ls
#=GF BM hmmbuild -f -FHMM_fs.ann SEED.ann
#=GF BM hmmcalibrate --seed 0 HMM_fs
#=GF AM byscore
#=GF RN [1]
#=GF RM 2169613
#=GF RT Structural design and molecular evolution of a cytokine receptor
#=GF RT superfamily.
#=GF RA Bazan JF;
#=GF RL PNAS USA 1990;87:6934-6938.
#=GF RN [2]
#=GF RM 7528812
#=GF RT Tracing the spread of fibronectin type III domains in bacterial
#=GF RT glycohydrolases.
#=GF RA Little E, Bork P, Doolittle R;
#=GF RL J Mol Evol 1994;39:631-643.
#=GF RC Definition of fibronectin domains
#=GF RN [3]
#=GF RM 2992939
#=GF RT Primary structure of human fibronectin: differential splicing
#=GF RT may generate at least 10 polypeptides from a single gene.
#=GF RA Kornblihtt AR, Umezawa K, Vibe-Pedersen K, Baralle FE;
#=GF RL EMBO J 1985;4:1755-1759.
#=GF DR INTERPRO; IPR003961;
#=GF DR HOMSTRAD; fn3;
#=GF DR SMART; FN3;
#=GF DR SCOP; 1ttf; sf;
#=GF DR PRINTS; PR00014;
#=GF DR PROSITE; PDOC00214;
#=GF SQ 106
#=GS TIE1_HUMAN/644-729 AC P35590.1
#=GS NCAM1_BOVIN/509-597 AC P31836.1
#=GS LAR_DROME/417-503 AC P16621.2
#=GS NGCA_CHICK/700-794 AC Q03696.2
#=GS MPSF_CHICK/499-585 AC Q02173.1
#=GS MPSF_CHICK/371-457 AC Q02173.1
#=GS MPSF_CHICK/600-684 AC Q02173.1
#=GS NRCAM_CHICK/623-709 AC P35331.1
#=GS MYPC2_CHICK/631-717 AC P16419.3
#=GS MYLK_CHICK/1318-1403 AC P11799.2
#=GS CNTN2_CHICK/602-692 AC P28685.1
#=GS MPSF_CHICK/699-785 AC Q02173.1
#=GS MPSF_CHICK/801-887 AC Q02173.1
#=GS MYPC2_CHICK/924-1006 AC P16419.3
#=GS LAR_DROME/322-404 AC P16621.2
#=GS FAS2_SCHAM/530-616 AC P22648.2
#=GS PTP69_DROME/332-425 AC P16620.2
#=GS TENA_CHICK/1227-1306 AC P10039.2
#=GS TENA_CHICK/1136-1215 AC P10039.2
#=GS TENA_HUMAN/1529-1608 AC P24821.2
#=GS TENA_CHICK/1045-1124 AC P10039.2
#=GS TENA_HUMAN/1255-1335 AC P24821.2
#=GS PTPRB_HUMAN/22-103 AC P23467.1
#=GS TIE2_HUMAN/639-724 AC Q02763.1
#=GS LAR_DROME/515-598 AC P16621.2
#=GS FINC_BOVIN/577-660 AC P07589.3
#=GS TIE1_HUMAN/446-533 AC P35590.1
#=GS PTPRK_MOUSE/290-376 AC P35822.1
#=GS TIE2_HUMAN/444-529 AC Q02763.1
#=GS TIE2_HUMAN/543-626 AC Q02763.1
#=GS 7LESS_DROVI/1917-1997 AC P20806.1
#=GS PTPRZ_HUMAN/312-401 AC P23471.3
#=GS FAS2_SCHAM/642-735 AC P22648.2
#=GS NCAM1_BOVIN/610-691 AC P31836.1
#=GS ITB4_HUMAN/1127-1208 AC P16144.4
#=GS UFO_HUMAN/327-411 AC P30530.2
#=GS KALM_CHICK/543-641 AC P33005.2
#=GS PTP10_DROME/958-1044 AC P35992.3
#=GS PTP69_DROME/236-321 AC P16620.2
#=GS NRG_DROME/917-1007 AC P20241.2
#=GS FINC_BOVIN/689-768 AC P07589.3
#=GS FINC_BOVIN/780-858 AC P07589.3
#=GS IL7RA_HUMAN/129-221 AC P16871.1
#=GS PTP10_DROME/405-485 AC P35992.3
#=GS FINC_BOVIN/1417-1499 AC P07589.3
#=GS FINC_RAT/1266-1346 AC P04937.2
#=GS FINC_BOVIN/1327-1406 AC P07589.3
#=GS TENA_CHICK/1317-1395 AC P10039.2
#=GS FINC_BOVIN/875-955 AC P07589.3
#=GS FINC_BOVIN/1511-1590 AC P07589.3
#=GS TENA_CHICK/864-945 AC P10039.2
#=GS TENA_CHICK/593-671 AC P10039.2
#=GS FINC_BOVIN/1142-1225 AC P07589.3
#=GS FINC_BOVIN/1693-1771 AC P07589.3
#=GS FINC_BOVIN/1236-1316 AC P07589.3
#=GS FINC_BOVIN/1601-1680 AC P07589.3
#=GS TENA_CHICK/1494-1571 AC P10039.2
#=GS TENA_CHICK/956-1033 AC P10039.2
#=GS TENA_CHICK/682-767 AC P10039.2
#=GS TENA_CHICK/774-853 AC P10039.2
#=GS TENA_CHICK/1406-1483 AC P10039.2
#=GS FINC_BOVIN/1782-1861 AC P07589.3
#=GS PTPRB_HUMAN/1085-1162 AC P23467.1
#=GS PTPRB_HUMAN/1173-1250 AC P23467.1
#=GS PTPRB_HUMAN/554-632 AC P23467.1
#=GS PTPRB_HUMAN/643-725 AC P23467.1
#=GS PTPRB_HUMAN/731-808 AC P23467.1
#=GS PTPRB_HUMAN/995-1074 AC P23467.1
#=GS PTPRB_HUMAN/467-543 AC P23467.1
#=GS PTPRB_HUMAN/907-984 AC P23467.1
#=GS PTPRB_HUMAN/112-192 AC P23467.1
#=GS PTPRB_HUMAN/1355-1434 AC P23467.1
#=GS PTP10_DROME/583-661 AC P35992.3
#=GS PTP10_DROME/312-394 AC P35992.3
#=GS PTP10_DROME/217-301 AC P35992.3
#=GS PTP10_DROME/123-205 AC P35992.3
#=GS EPHA2_HUMAN/329-420 AC P29317.1
#=GS EPHA1_HUMAN/333-431 AC P21709.3
#=GS EPHB2_CHICK/326-422 AC P28693.3
#=GS EPHA3_CHICK/325-421 AC P29318.1
#=GS PTP10_DROME/864-944 AC P35992.3
#=GS PTPRB_HUMAN/1261-1344 AC P23467.1
#=GS TIE1_HUMAN/545-632 AC P35590.1
#=GS 7LESS_DROME/1799-1891 AC P13368.2
#=GS PHB_ALCFA/344-418 AC P12625.1
#=GS APU_THETY/928-1009 AC P16950.1
#=GS CHIT_STRLI/142-219 AC P36909.1
#=GS CHIA1_BACCI/465-542 AC P20533.1
#=GS GUNB_CELFI/651-733 AC P26225.1
#=GS CHIX_STROI/169-240 AC Q05638.1
#=GS APU_THETY/1165-1248 AC P16950.1
#=GS KALM_CHICK/177-269 AC P33005.2
#=GS CNTN1_CHICK/799-884 AC P14781.1
#=GS CNTN2_CHICK/807-896 AC P28685.1
#=GS NRG_DROME/815-905 AC P20241.2
#=GS L1CAM_HUMAN/812-907 AC P32004.2
#=GS LAR_DROME/709-800 AC P16621.2
#=GS PTP99_DROME/171-259 AC P35832.2
#=GS EPHA2_HUMAN/436-519 AC P29317.1
#=GS LAR_DROME/909-995 AC P16621.2
#=GS NRCAM_CHICK/928-1014 AC P35331.1
#=GS EPHB2_CHICK/437-521 AC P28693.3
#=GS EPHA4_MOUSE/441-525 AC Q03137.1
#=GS ITB4_HUMAN/1220-1310 AC P16144.4
#=GS ITB4_HUMAN/1641-1728 AC P16144.4
#=GS ITB4_HUMAN/1528-1612 AC P16144.4
#=GS TENA_CHICK/1227-1306 DR PDB; 1qr4 B; 18-77;
#=GS TENA_CHICK/1227-1306 DR PDB; 1qr4 A; 18-77;
#=GS ITB4_HUMAN/1127-1208 DR PDB; 1qg3 B; 1127-1208;
#=GS ITB4_HUMAN/1127-1208 DR PDB; 1qg3 A; 1127-1208;
#=GS TENA_CHICK/1317-1395 DR PDB; 1qr4 B; 88-166;
#=GS TENA_CHICK/1317-1395 DR PDB; 1qr4 A; 88-166;
#=GS ITB4_HUMAN/1220-1310 DR PDB; 1qg3 B; 1220-1310;
#=GS ITB4_HUMAN/1220-1310 DR PDB; 1qg3 A; 1220-1310;
TIE1_HUMAN/644-729 P.PAP.RHLHAQAL...SDSEIQLTWKHPE..ALPGPISKYVVEV...QV
NCAM1_BOVIN/509-597 P.SSP.SIDQVEP....YSSTAQVQFDEPEA.TGGVPILKYKAEWR...A
LAR_DROME/417-503 E.SAP.RNVQVRTL...SSSTMVITWEPPE..TPNGQVTGYKV.Y...YT
NGCA_CHICK/700-794 PERNP.GGVHGEGN...ETGNLVITWEPLPPQAWNAPWARYRVQWR...P
MPSF_CHICK/499-585 P.GPP.TNVHASEI...SKTYVVLSWDPPV..PRGREPLTYFIEK...SM
MPSF_CHICK/371-457 P.GAP.MDVKCHDA...NRDYVIVTWKPPNT.TSQNPVIGYFVDK...CE
MPSF_CHICK/600-684 P.SAP.GRVVATRN...TKTSVVVQWDKPK...HEENLYGYYIDY...SV
NRCAM_CHICK/623-709 P.NPP.LDLELTGQ...LERSIELSWVPGE..ENNSPITNFVIEY...ED
MYPC2_CHICK/631-717 P.DPP.QSVRVTSV...GEDWAVLSWEAPPF.DGGMPITGYLMER...KK
MYLK_CHICK/1318-1403 P.DPPAGTPCASDI...RSSSLTLSWYGSSY.DGGSAVQSYTVEI...WN
CNTN2_CHICK/602-692 PPGPP.GGVVVRDI...GDTTVQLSWSRGF..DNHSPIARYSIEAR...T
MPSF_CHICK/699-785 P.SYP.HGITLLNC...DGHSMTLGWKAPKY.SGGSPILGYYIDKR...E
MPSF_CHICK/801-887 P.GPA.YDLTVCEV...RNTSLVLLWKAPVY.EGKSPITGYLVDY...KE
MYPC2_CHICK/924-1006 P.GPP.QAVRVMEV...WGSNALLQWEPPKD.DGNAEISGYTVQK...AD
LAR_DROME/322-404 P.TAP.TDVQISEV...TATSVRLEWSYK....GPEDLQYYVIQY...KP
FAS2_SCHAM/530-616 P.SAV.LQVKMDVM...TATTVTFKFFGPGN.DGGLPTKNYAVQY...KQ
PTP69_DROME/332-425 Y.DPI.FIPKVETTG.STASTITIGWNPPPP.DLIDYIQYYELIV...SE
TENA_CHICK/1227-1306 E.PEV.DNLLVSDA...TPDGFRLSWTAD.....DGVFDSFVLKIR..DT
#=GR TENA_CHICK/1227-1306 SS X.XXX.XXXXXXXX...XXXXXXEEEE--.....SS--SEEEEEEE..-T
TENA_CHICK/1136-1215 H.PEV.GELTVSDI...TPESFNLSWTTT.....NGDFDAFTIEI...ID
TENA_HUMAN/1529-1608 L.PLL.ENLTISDI...NPYGFTVSWMAS.....ENAFDSFLVTV...VD
TENA_CHICK/1045-1124 E.PEL.GNLSVSET...GWDGFQLTWTAA.....DGAYENFVIQV...QQ
TENA_HUMAN/1255-1335 E.VPDMGNLTVTEV...SWDALRLNWTTP.....DGTYDQFTIQV...QE
PTPRB_HUMAN/22-103 AEPER.CNFTLAESK.ASSHSVSIQWRIL......GSPCNFSLIY...SS
TIE2_HUMAN/639-724 P.PQP.ENIKISNI...THSSAVISWTILD....GYSISSITIRY...KV
LAR_DROME/515-598 P.SQP.SNFRATDI...GETAVTLQWTKPT..HSSENIVHYELYW...ND
FINC_BOVIN/577-660 T.SGP.VQVIITETP.SQPNSHPIQWSAPE....SSHISKYILRW...KP
TIE1_HUMAN/446-533 P.PVPLAAPRLLTK...QSRQLVVSPLVSF..SGDGPISTVRLHYR..PQ
PTPRK_MOUSE/290-376 P.PRPIAPPQLLGV...GPTYLLIQLNANSI.IGDGPIILKEVEYR...M
TIE2_HUMAN/444-529 L.PKPLNAPNVIDT...GHNFAVINISSEPY.FGDGPIKSKKLLY...KP
TIE2_HUMAN/543-626 L.PPP.RGLNLLPK...SQTTLNLTWQPIF..PSSEDDFYVEVERR...S
7LESS_DROVI/1917-1997 S.YAPLPPLQLIEL...NAYGMTLAWPGT.....PDALSSLTLEC...QS
PTPRZ_HUMAN/312-401 S.SEP.ENVQADPE...NYTSLLVTWERPRV.VYDTMIEKFAVLY...QQ
FAS2_SCHAM/642-735 T.SGT.ENEVVVSP...YPNRYELRWQVPA..DNGEPITHYSVKS...CP
NCAM1_BOVIN/610-691 P.SAP.KLEGQMGE...DGNSIKVKLIKQD..DGGSPIRHYLVKYR...A
ITB4_HUMAN/1127-1208 L.GAP.QNPNAKAA...GSRKIHFNWLPP.....SGKPMGYRVKY...WI
#=GR ITB4_HUMAN/1127-1208 SS -.---.EEEEEEE-...STT-EEEEEE--.....SS---EEEEEE...EE
UFO_HUMAN/327-411 L.GPP.ENISATR....NGSQAFVHWQEPRA.PLQGTLLGYRLAY...QG
KALM_CHICK/543-641 L.AKP.ENLSASFIVQEGNITGHFSWKISKA.VLHQPMTGFQVTW...AE
PTP10_DROME/958-1044 P.GRV.ERFHPTDV...QPSEINFEWSLPSS.EANGVIRQFSIAY...TN
PTP69_DROME/236-321 V.PQV.SIDFAKAV...GANKIYLNWTVND...GNDPIQKFFITL...QE
NRG_DROME/917-1007 P.SPV.QGLDAYPL...GSSAFMLHWKKPL..YPNGKLTGYKIYY...EE
FINC_BOVIN/689-768 P.VVA.TSESVTEI...TASSFVVSWVSA.....SDTVSGFRVEY...EL
FINC_BOVIN/780-858 P.DAP.PDPTVDQV...DDTSIVVRWSRP.....RAPITGYRIVY...SP
IL7RA_HUMAN/129-221 P.EAP.FDLSVIYR..EGANDFVVTFNTSHLQKKYVKVLMHDVAYR..QE
PTP10_DROME/405-485 P.LPV.RNLRSIND..DKTNTMIITWEADP....ASTQDEYRIVYH.ELE
FINC_BOVIN/1417-1499 S.DVP.RDLEVIAA...TPTSLLISWDAP.....AVTVRYYRITY...GE
FINC_RAT/1266-1346 V.PQL.TDLSFVDI...TDSSIGLRWTPLN....SSTIIGYRITV...VA
FINC_BOVIN/1327-1406 L.DSP.SGIDFSDI...TANSFTVHWIAP.....RATITGYRIRHH...P
TENA_CHICK/1317-1395 V.GSP.KGISFSDI...TENSATVSWTPP.....RSRVDSYRVSY...VP
#=GR TENA_CHICK/1317-1395 SS -.---.SEEEEES-...-SS-EEEEEE--.....SS--SEEEEEE...EE
FINC_BOVIN/875-955 KVPPP.RDLQFVEV...TDVKITIMWTPP.....ESPVTGYRVDV...IP
FINC_BOVIN/1511-1590 I.DKP.SQMQVTDV...QDNSISVRWLPS.....SSPVTGYRVTT...AP
TENA_CHICK/864-945 L.DAP.RNLKRVSQ...TDNSITLEWKNS.....HANIDNYRIKF...AP
TENA_CHICK/593-671 V.SPP.TELTVTNV...TDKTVNLEWKHE......NLVNEYLVTY...VP
FINC_BOVIN/1142-1225 PLSPP.TNLHLEAN..PDTGVLTVSWERST....TPDITGYRITT...TP
FINC_BOVIN/1693-1771 V.SPP.RRARVTDA...TETTITISWRTK.....TETITGFQVDA...IP
FINC_BOVIN/1236-1316 V.PPP.TDLRFTNV...GPDTMRVTWAPPS....SIELTNLLVRY...SP
FINC_BOVIN/1601-1680 I.PAP.TNLKFTQV...TPTSLTAQWTAP.....NVQLTGYRVRV...TP
TENA_CHICK/1494-1571 L.DAP.KDLSATEV...QSETAVITWRPP.....RAPVTDYLLTY...ES
TENA_CHICK/956-1033 L.DNP.KDLEVSDP...TETTLSLRWRRP.....VAKFDRYRLTY...VS
TENA_CHICK/682-767 L.PAP.EGLKFKSV...RETSVQVEWDPL.....SISFDGWELVFRNMQK
TENA_CHICK/774-853 L.DAP.SQIEAKDV...TDTTALITWSKP.....LAEIEGIELTY...GP
TENA_CHICK/1406-1483 L.DSP.SGLVVMNI...TDSEALATWQPA.....IAAVDNYIVSY...SS
FINC_BOVIN/1782-1861 I.DAP.SNLRFLAT...TPNSLLVSWQPP.....RARITGYIIKY...EK
PTPRB_HUMAN/1085-1162 P.AAV.TDLRITEN...STRHLSFRWTAS.....EGELSWYNIFL...YN
PTPRB_HUMAN/1173-1250 P.ASV.SHLRGSNR..NTTDSLWFNWSPA.....SGDFDFYELIL...YN
PTPRB_HUMAN/554-632 P.AQV.TDLHVANQ..GMTSSLFTNWTQA.....QGDVEFYQVLL...IH
PTPRB_HUMAN/643-725 P.SSV.SGVTVNNS..GRNDYLSVSWLVA.....PGDVDNYEVTL...SH
PTPRB_HUMAN/731-808 P.DKV.QGVSVSNS..ARSDYLRVSWVHA.....TGDFDHYEVTI...KN
PTPRB_HUMAN/995-1074 P.ASV.QGVIADNA..YSSYSLIVSWQKA.....AGVAERYDILL...LT
PTPRB_HUMAN/467-543 P.LAV.LQLRVKHA...NETSLSIMWQTP.....VAEWEKYIISL...AD
PTPRB_HUMAN/907-984 P.SAV.KNIHISPN..GATDSLTVNWTPG.....GGDVDSYTVSA...FR
PTPRB_HUMAN/112-192 P.PAR.FGVSKEKT...TSTGLHVWWTPS.....SGKVTSYEVQL...FD
PTPRB_HUMAN/1355-1434 P.DKI.QNLHCRPQ...NSTAIACSWIPP.....DSDFDGYSIECR...K
PTP10_DROME/583-661 P.NPP.RNMTIETV...RSNSVLVHWSPPE....SGEFTEYSIRYR...T
PTP10_DROME/312-394 P.LRP.LNVTFDRDF.ITSNSFRVLWEAPK...GISEFDKYQVSV...AT
PTP10_DROME/217-301 P.NTP.GKFIVWFR...NETTLLVLWQPPY...PAGIYTHYKVSI...EP
PTP10_DROME/123-205 P.DPP.SNLSVQVR...SGKNAIILWSPPT....QGSYTAFKIKV...LG
EPHA2_HUMAN/329-420 P.SAP.HYLTAVGM...GA.KVELRWTPPQD.SGGREDIVYSVTCEQCWP
EPHA1_HUMAN/333-431 P.SAP.RNLSFSA....SGTQLSLRWEPPAD.TGGRQDVRYSVRC...SQ
EPHB2_CHICK/326-422 P.SAP.QAV.ISSV...NETSLMLEWTPPRD.SGGREDLVYNIIC...KS
EPHA3_CHICK/325-421 P.SAP.RNV.ISNI...NETSVILDWSWPLD.TGGRKDVTFNIIC...KK
PTP10_DROME/864-944 P.EPI.TQLHATNI...TDTEISLRWDLP.....KGEYNDFDIAY...LT
PTPRB_HUMAN/1261-1344 P.SPP.SLMSFADI...ANTSLAITWKGPP...DWTDYNDFELQW...LP
TIE1_HUMAN/545-632 PLLQP.WLEGWHVE...GTDRLRVSWSLPLV.PGPLVGDGFLLRL...WD
7LESS_DROME/1799-1891 P.SPP.RNFSVRVL...SPRELEVSWLPPE..QLRSESVYYTLHW...QQ
PHB_ALCFA/344-418 G.SAP.TGLAVTAT...TSTSVSLSWNAV......ANASSYGV.YR....
APU_THETY/928-1009 A.PQPITDLKAVS....GNGKVDLSWSVV......DKAVSYNI.YR...S
CHIT_STRLI/142-219 P.SAP.GTPTASNI...TDTSVKLSWSAAT...DDKGVKNYDV.LR....
CHIA1_BACCI/465-542 P.SVP.GNARSTGV...TANSVTLAWNAST...DNVGVTGYNV.YN....
GUNB_CELFI/651-733 P.TTP.GTPVATGV...TTVGASLSWAAST..DAGSGVAGYEL.YR...V
CHIX_STROI/169-240 P.PAPPTGLRTGSV...TATSVALSWSPV......TGATGYAV.YR....
APU_THETY/1165-1248 P.TAP.V.LQQPGI...ESSRVTLNWSPSA...DDVAIFGYEIYK...SS
KALM_CHICK/177-269 P.LKPRKELKFIEL...QSGDLEVKWSSKF..NISIEPVIYVVQRR..WN
CNTN1_CHICK/799-884 PTEVP.TDVSVKVL...SSSEISVSWHHVT....EKSVEGYQIRY...WA
CNTN2_CHICK/807-896 PKVAP.FRVTAKAV...LSSEMDVSWEPVEQGDMTGVLLGYEIRY...WK
NRG_DROME/815-905 PLDAP.TNFTMRQI..TSSTSGYMAWTPVSEESVRGHFKGYKIQT...WT
L1CAM_HUMAN/812-907 P.QAI.PELEGIEI..LNSSAVLVKWRPVDLAQVKGHLRGYNVTY...WR
LAR_DROME/709-800 P.GDP.QDVKATPL...NSTSIHVSWKPPLEKDRNGIIRGYHIHA...QE
PTP99_DROME/171-259 P.SKP.QNLTILDV...SANSITMSWHPPK..NQNGAIAGYHVFH...IH
EPHA2_HUMAN/436-519 Q.TEP.PKVRLEGR...STTSLSVSWSIPP..PQQSRVWKYEVTYR...K
LAR_DROME/909-995 PGGPP.SNITIRFQ...TPDVLCVTWDPPTREHRNGIITRYDVQFH..KK
NRCAM_CHICK/928-1014 P.SPP.SFLKITNP...TLDSLTLEWGSPT..HPNGVLTSYILKF...QP
EPHB2_CHICK/437-521 P.SAV.SIMHQVSR...TVDSITLSWSQPD..QPNGVILDYELQY...YE
EPHA4_MOUSE/441-525 P.SSI.ALVQAKEV...TRYSVALAWLEPD..RPNGVILEYEVKY...YE
ITB4_HUMAN/1220-1310 P.SEP.GRLAFNVV...SSTVTQLSWAEPA..ETNGEITAYEVCY...GL
#=GR ITB4_HUMAN/1220-1310 SS -.---.---EEEEE...CTTEEEEE----S..--SS---EEEEEE...EE
ITB4_HUMAN/1641-1728 P.SAP.GPLVFTAL...SPDSLQLSWERPR..RPNGDIVGYLVTC...EM
ITB4_HUMAN/1528-1612 P.DTP.TRLVFSAL...GPTSLRVSWQEPR...CERPLQGYSVEY...QL
#=GC SS_cons -.---.CEEEEEEE...CTTEEEEEEE--S..--SS--SEEEEEEE..EE
#=GC seq_cons P.ssP.pslphpsh...sssslplsWpss.....suslssYplph....p
TIE1_HUMAN/644-729 AGGAG..........DPLWID...VDRP....EE.TSTIIRGL.NASTRY
NCAM1_BOVIN/509-597 MGEEVW.........HSKWYD...AKEA....SMEGIVTIVGL.KPETTY
LAR_DROME/417-503 TNSNQPE.......ASWNSQM...VDNS....E...LTTVSEL.TPHAIY
NGCA_CHICK/700-794 LEEPGGGGP..SGGFPWAEST...VDAP....P....VVVGGL.PPFSPF
MPSF_CHICK/499-585 VGSGS...........WQRVNAQVAVKS....P...RYAVFDL.AEGKPY
MPSF_CHICK/371-457 VGLEN...........WVQCN...DAPV....KI.CKYPVTGL.YEGRSY
MPSF_CHICK/600-684 VGSNQW........EPANHKP...INYN....R....FVVHGL.ETGEQY
NRCAM_CHICK/623-709 GLHEPG.........VWHYQT...EVPG....SH..TTVQLKL.SPYVNY
MYPC2_CHICK/631-717 KGSMRW.........MKLNFE...VFPD....T...TYESTKM.IEGVFY
MYLK_CHICK/1318-1403 SVDNK...........WTDLT...TCRS....T...SFNVQDL.QADREY
CNTN2_CHICK/602-692 LLSNKWK......QMRTNPVN...IEGN....AE..TAQVVNL.IPWMDY
MPSF_CHICK/699-785 ANHKN...........WHEVNSSVISRT....I....YTVEDL.TEDAFY
MPSF_CHICK/801-887 VDTED...........WITAN...EKPT....SH.RYFKVTDL.HQGHTY
MYPC2_CHICK/924-1006 TRTME...........WFTVL...EHSR....PT..RCTVSEL.VMGNEY
LAR_DROME/322-404 KNANQ...........AFSEI...SGII....TM..YYVVRAL.SPYTEY
FAS2_SCHAM/530-616 DSQGW...........EDALN...RTWP....VD.SPYILENL.KPQTRY
PTP69_DROME/332-425 SGEVPKV......IEEAIYQQ...NSRN....L...PYMFDKL.KTATDY
TENA_CHICK/1227-1306 KRKSD...........PLELI...VPGH....ER..THDITGL.KEGTEY
#=GR TENA_CHICK/1227-1306 SS T--EE...........EEEXX...E-TT....-S..EEEEES-.-TT-EE
TENA_CHICK/1136-1215 SNRLL..........EPMEFN...ISGN....SR..TAHISGL.SPSTDF
TENA_HUMAN/1529-1608 SGKLL..........DPQEFT...LSGT....QR..KLELRGL.ITGIGY
TENA_CHICK/1045-1124 SDNPE..........ETWNIT...VPGG....QH..SVNVTGL.KANTPY
TENA_HUMAN/1255-1335 ADQVE..........EAHNLT...VPGS....LR..SMEIPGL.RAGTPY
PTPRB_HUMAN/22-103 DTLGAA.........LCPTFR...IDNT....TY..GCNLQDL.QAGTIY
TIE2_HUMAN/639-724 QGKNE...........DQHVDV.KIKNA....TI.IQYQLKGL.EPETAY
LAR_DROME/515-598 TYANQ...........AHHKR...ISNS....E...AYTLDGL.YPDTLY
FINC_BOVIN/577-660 KNSPD..........RWKEAT...IPGH....LN..SYTIKGL.RPGVVY
TIE1_HUMAN/446-533 DSTMD...........WSTIV...VDPS....E...NVTLMNL.RPKTGY
PTPRK_MOUSE/290-376 T.SGS...........WTETH...AVNA....P...TYKLWHL.DPDTEY
TIE2_HUMAN/444-529 VNHYE..........AWQHIQ...VTNE....I....VTLNYL.EPRTEY
TIE2_HUMAN/543-626 VQKSD...........QQNIK...VPGN....LT..SVLLNNL.HPREQY
7LESS_DROVI/1917-1997 LREQ.............LQFN...VAGN....HT..QMRLAPL.QPKTRY
PTPRZ_HUMAN/312-401 LDGEDQ.........TKHEFL...TDGY....QD.LGAILNNL.LPNMSY
FAS2_SCHAM/642-735 VEKYDTEWR..LLPYPCQEHK...LEGQ....AT..TFQLESL.QPDTHY
NCAM1_BOVIN/610-691 LSSEW...........KPEIR...LPSG....SD..HVMLKSL.DWNAEY
ITB4_HUMAN/1127-1208 QGDSE..........SEAHLL...DSKV....P...SVELTNL.YPYCDY
#=GR ITB4_HUMAN/1127-1208 SS TTS-G..........GG-EEE...EESS....S...EEEE-S-.-TT-EE
UFO_HUMAN/327-411 QDTPE...........VLMDI...GLRQ....EV..TLELQGD.GSVSNL
KALM_CHICK/543-641 VTTESRQNSL.PNSIISQSQI...LPAD....HY..VLTVPNL.RPSMLY
PTP10_DROME/958-1044 INNLT...........DAGMQ...DFES....EE.AFGVIKNL.KPGETY
PTP69_DROME/236-321 AGTPTF........TYHKDFI...NGSH....T...SYILDHF.KPNTTY
NRG_DROME/917-1007 V.KESYVGE...RREYDPHIT...DPRV....T...RMKMAGL.KPNSKY
FINC_BOVIN/689-768 SEEGD..........EPQYLD...LPST....AT..SVNIPDL.LPGRKY
FINC_BOVIN/780-858 SVEGS...........STELN...LPET....AN..SVTLSDL.QPGVQY
IL7RA_HUMAN/129-221 KDENK...........WTHVN...LSST....KL..TLLQRKL.QPAAMY
PTP10_DROME/405-485 TFNGD...........TSTLT...TDRT....R....FTLESL.LPGRNY
FINC_BOVIN/1417-1499 TGGSS..........PVQEFT...VPGS....KS..TATISGL.KPGVDY
FINC_RAT/1266-1346 AGEGI..........PIFEDF...VDSS....VG..YYTVTGL.EPGIDY
FINC_BOVIN/1327-1406 ENMGG..........RPREDR...VPPS....RN..SITLTNL.NPGTEY
TENA_CHICK/1317-1395 ITGGT...........PNVVT...VDGS....KT..RTKLVKL.VPGVDY
#=GR TENA_CHICK/1317-1395 SS TT-B-...........-EEEE...EETT....-S..EEEE-S-.-SS-EE
FINC_BOVIN/875-955 VNLPGE.........HGQRLP...VSRN....T...FAEVTGL.SPGVTY
FINC_BOVIN/1511-1590 KNGPG..........PSKTKT...VGPD....QT..EMTIEGL.QPTVEY
TENA_CHICK/864-945 ISGGD...........HTELT...VPKGN.QATT..RATLTGL.RPGTEY
TENA_CHICK/593-671 TSSGG..........LDLQFT...VPGN....QT..SATIHEL.EPGVEY
FINC_BOVIN/1142-1225 TNGQQG.........YSLEEV...VHAD....QS..SCTFENL.SPGLEY
FINC_BOVIN/1693-1771 ANGQT...........PIQRT...IRPD....VR..SYTITGL.QPGTDY
FINC_BOVIN/1236-1316 VKNEE..........DVAELS...ISPS....DN..AVVLTNL.LPGTEY
FINC_BOVIN/1601-1680 KEKTG..........PMKEIN...LAPD....SS..SVVVSGL.MVATKY
TENA_CHICK/1494-1571 I.DGR...........VKEVI...LDPE....TT..SYTLTEL.SPSTQY
TENA_CHICK/956-1033 P.SGK...........KNEME...IPVD....ST..SFILRGL.DAGTEY
TENA_CHICK/682-767 KDDNG...........DITSS...LKRP....ET..SYMQPGL.APGQQY
TENA_CHICK/774-853 KDVPG..........DRTTID...LSED....EN..QYSIGNL.RPHTEY
TENA_CHICK/1406-1483 EDEP............EVTQM...VSGN....TV..EYDLNGL.RPATEY
FINC_BOVIN/1782-1861 PGSPPR.........EVVPRP...RPGV....T...EATITGL.EPGTEY
PTPRB_HUMAN/1085-1162 PDGNL..........QERAQV...DPLV....Q...SFSFQNL.LQGRMY
PTPRB_HUMAN/1173-1250 PNGTK..........KENWKD...KDLT....E....WRFQGL.VPGRKY
PTPRB_HUMAN/554-632 ENVV............IKNES...ISSE....TS..RYSFHSL.KSGSLY
PTPRB_HUMAN/643-725 DGKV............VQSLV...IAKS....VR..ECSFSSL.TPGRLY
PTPRB_HUMAN/731-808 KNNF............IQTKS...IPKS....EN..ECVFVQL.VPGRLY
PTPRB_HUMAN/995-1074 ENGIL...........LRNTS...EPAT....TK..QHKFEDL.TPGKKY
PTPRB_HUMAN/467-543 R.DLL...........LIHKS...LSKD....AK..EFTFTDL.VPGRKY
PTPRB_HUMAN/907-984 H.SQK...........VDSQT...IPKH....VF..EHTFHRL.EAGEQY
PTPRB_HUMAN/112-192 ENNQKIQ.......GVQIQES...TSWN....E....YTFFNL.TAGSKY
PTPRB_HUMAN/1355-1434 MDTQE..........VEFSRK...LEKE....KS..LLNIMML.VPHKRY
PTP10_DROME/583-661 DSEQQ...........WVRLP...SVRS....T...EADITDM.TKGEKY
PTP10_DROME/312-394 TRRQS...........TVPRS...NEPV....A...FFDFRDIAEPGKTF
PTP10_DROME/217-301 PDANDSV......LYVEKEGE...PPGP....A...QAAFKGL.VPGRAY
PTP10_DROME/123-205 LSEASS........SYNRTFQ...VNDN....TF..QHSVKEL.TPGATY
EPHA2_HUMAN/329-420 E.SGECGP.....CEASVRYS...EPPHG.LTRT..SVTVSDL.EPHMNY
EPHA1_HUMAN/333-431 CQGTAQDGGPCQPCGVGVHFSPGARGLT....TP..AVHVNGL.EPYANY
EPHB2_CHICK/326-422 CGSGRGAC....TRCGDNVQF...APRQLGLTEP..RIYISDL.LAHTQY
EPHA3_CHICK/325-421 CGGSSKIC....EPCSDNVRF...LPRQT.GLTN.TTVTVVDL.LAHTNY
PTP10_DROME/864-944 A.DNL...........LAQNM...TTRN....E....ITISDL.RPHRNY
PTPRB_HUMAN/1261-1344 RDALT..........VFNPYN...NRKS....E...GRIVYGL.RPGRSY
TIE1_HUMAN/545-632 GTRGQ...........ERREN...VSSP....QA.RTALLTGL.TPGTHY
7LESS_DROME/1799-1891 ELDGENVQD...RREWEAHER...RLET....AG..THRLTGI.KPGSGY
PHB_ALCFA/344-418 .NGS.............KVGS...ATAT....A....YTDSGL.IAGTTY
APU_THETY/928-1009 TVKGG...........LYEKI...ASNV....TQ.ITYTDTEV.TNGLKY
CHIT_STRLI/142-219 .DGA.............KVAT...VTGT....T....YTDNGL.TKGTAY
CHIA1_BACCI/465-542 .GAN.............LATS...VTGT....T....ATISGL.TAGTSY
GUNB_CELFI/651-733 QGTTQ...........TLVGT...TTAA....A....YILRDL.TPGTAY
CHIX_STROI/169-240 .DGV.............KVAT...ASGT....S....ATVTGL.TPDTAY
APU_THETY/1165-1248 SETGP..........FIKIAT...VSDS....VY..NYVDTDV.VNGNVY
KALM_CHICK/177-269 Q.GIHPSE.....DDATNWQT...VAQT....TD.ERVQLSDI.RASRWY
CNTN1_CHICK/799-884 AHDKEA.........AAQRVQ...VSNQ....EY..STKLENL.KPNTRY
CNTN2_CHICK/807-896 DGDKEE........AADRVRT...AGLV....T...SAHVTGL.NPNTKY
NRG_DROME/815-905 ENEGEE.........GLREIH...VKGD....TH..NALVTQF.KPDSKN
L1CAM_HUMAN/812-907 EGSQRKHSK...RHIHKDHVV...VPAN....TT..SVILSGL.RPYSSY
LAR_DROME/709-800 LRDEGKGF.....LNEPFKFD...VVDT....L...EFNVTGL.QPDTKY
PTP99_DROME/171-259 DNQTGVE.......IVKNSRN...SVET....LI..HFELQNL.RPYTDY
EPHA2_HUMAN/436-519 KGDS.............NSYN...VRRT....EG.FSVTLDDL.APDTTY
LAR_DROME/909-995 IDHGL...........GSERN...MTLR....K....AVFTNL.EENTEY
NRCAM_CHICK/928-1014 INNTHEL.......GPLVEIR...IPAN....ES..SLILKNL.NYSTRY
EPHB2_CHICK/437-521 KNLSE...........LNSTA...VKSP....TN..TVTVQNL.KAGTIY
EPHA4_MOUSE/441-525 KDQN............ERSYR...IVRT....AA.RNTDIKGL.NPLTSY
ITB4_HUMAN/1220-1310 VNDDNRP......IGPMKKVL...VDNP....KN.RMLLIENL.RESQPY
#=GR ITB4_HUMAN/1220-1310 SS B-TTS-B......-S--EEEE...E--T....T-.-EEEE---.-TT--E
ITB4_HUMAN/1641-1728 AQGGGP........ATAFRVD...GDSP....ES..RLTVPGL.SENVPY
ITB4_HUMAN/1528-1612 LNGGE...........LHRLN...IPNP....AQ.TSVVVEDL.LPNHSY
#=GC SS_cons TTTCC-B......-SGCEEEE...EETT....TS.-EEEEES-.-TT-EE
#=GC seq_cons tsssp...........hpphs...lsss....p...phslpsL.pPsspY
TIE1_HUMAN/644-729 LFRMR.ASI.QG....LGDWS
NCAM1_BOVIN/509-597 AVRLA.ALNGKG....LGEIS
LAR_DROME/417-503 TVRVQ.AYTSMG....AGPMS
NGCA_CHICK/700-794 QIRVQ.AVNGAG....KGPEA
MPSF_CHICK/499-585 VFRVL.SANKHG....ISDPS
MPSF_CHICK/371-457 IFRVR.AVNSAG....ISRPS
MPSF_CHICK/600-684 IFRVK.AVNAVG....FSENS
NRCAM_CHICK/623-709 SFRVI.AVNEIG....RSQPS
MYPC2_CHICK/631-717 EMRVF.AVNAIG....VSQPS
MYLK_CHICK/1318-1403 KFRVR.AANVYG....ISEPS
CNTN2_CHICK/602-692 EFRVL.ASNILG....VGEPS
MPSF_CHICK/699-785 EFKIA.AANVVG....IGHPS
MPSF_CHICK/801-887 VFKVR.AVNDAG....VGKSS
MYPC2_CHICK/924-1006 RFRVY.SENVC.......GTS
LAR_DROME/322-404 EFYVI.AVNNIG....RGPPS
FAS2_SCHAM/530-616 NFRFA.AQNEVG....FGPWS
PTP69_DROME/332-425 EFRVR.ACSDLTK..TCGPWS
TENA_CHICK/1227-1306 EIELY.GVSSG.......RRS
#=GR TENA_CHICK/1227-1306 SS EEEEE.EESSS.......-B-
TENA_CHICK/1136-1215 IVYLY.GISHG.......FRT
TENA_HUMAN/1529-1608 EVMVS.GFTQG.......HQT
TENA_CHICK/1045-1124 NVTLY.GVIRG.......YRT
TENA_HUMAN/1255-1335 TVTLH.GEVRG.......HST
PTPRB_HUMAN/22-103 NFKII.SLDEE........RT
TIE2_HUMAN/639-724 QVDIF.AENNIG....SSNPA
LAR_DROME/515-598 YIWLA.ARSQRG....EGATT
FINC_BOVIN/577-660 EGQLI.SVQHY......GQRE
TIE1_HUMAN/446-533 SVRVQLSRPGEGG...EGAWG
PTPRK_MOUSE/290-376 EIRVLLTRPGEGG...TGLPG
TIE2_HUMAN/444-529 ELCVQ.LVRRGE....GGEGH
TIE2_HUMAN/543-626 VVRAR..VNTKA....QGEWS
7LESS_DROVI/1917-1997 SCRLA.LAYAAT....PGAPI
PTPRZ_HUMAN/312-401 VLQIV.AICTNGL...YGKYS
FAS2_SCHAM/642-735 KVEVR.ATNAIG....NSVPG
NCAM1_BOVIN/610-691 EVYVV.AENQQ.......GKS
ITB4_HUMAN/1127-1208 EMKVC.AYGAQG....EGPYS
#=GR ITB4_HUMAN/1127-1208 SS EEEEE.EEETTE....E----
UFO_HUMAN/327-411 TVCVA.AYTAAG....DGPWS
KALM_CHICK/543-641 RLEVQ.VLTTGG....EGPAT
PTP10_DROME/958-1044 VFKIQ.AKTAIG....FGPER
PTP69_DROME/236-321 FLRIV.GKNSIG....NGQPT
NRG_DROME/917-1007 RISIT.ATTKMG....EGSEH
FINC_BOVIN/689-768 TVNVY.EISEE.......GEQ
FINC_BOVIN/780-858 NITIY.AVEEN.......QES
IL7RA_HUMAN/129-221 EIKVR.SIPDHYFKGFWSEWS
PTP10_DROME/405-485 SLSVQ.AVSKK.......MES
FINC_BOVIN/1417-1499 TITVY.AVTGRG....DSPAS
FINC_RAT/1266-1346 DISVI.TLING.......GES
FINC_BOVIN/1327-1406 VVSIV.ALNSK.......EES
TENA_CHICK/1317-1395 NVNII.SVKGF.......EES
#=GR TENA_CHICK/1317-1395 SS EEEEE.EEETT.......EE-
FINC_BOVIN/875-955 HFKVF.AVNQG.......RES
FINC_BOVIN/1511-1590 VVSVY.AQNQN.......GES
TENA_CHICK/864-945 GIGVT.AVRQD.......RES
TENA_CHICK/593-671 FIRVF.AILKN.......KKS
FINC_BOVIN/1142-1225 NVSVY.TVKDD.......KES
FINC_BOVIN/1693-1771 KIHLY.TLNDN.......ARS
FINC_BOVIN/1236-1316 LVSVS.SVYEQ.......HES
FINC_BOVIN/1601-1680 EVSVY.ALKDT.......LTS
TENA_CHICK/1494-1571 TVKLQ.ALSRS.......MRS
TENA_CHICK/956-1033 TISLV.AEKGR.......HKS
TENA_CHICK/682-767 NVSLH.IVKNNTR...GPGLS
TENA_CHICK/774-853 EVTLI.SRRGD.......MES
TENA_CHICK/1406-1483 TLRVH.AVKDA.......QKS
FINC_BOVIN/1782-1861 TIQVI.ALKNN.......QKS
PTPRB_HUMAN/1085-1162 KMVIV.THSGE........LS
PTPRB_HUMAN/1173-1250 VLWVV.THSGD........LS
PTPRB_HUMAN/554-632 SVVVT.TVSGG.......ISS
PTPRB_HUMAN/643-725 TVTIT.TRSGKYE...NHSFS
PTPRB_HUMAN/731-808 SVTVT.TKSGQ........YE
PTPRB_HUMAN/995-1074 KIQIL.TVSGG.......LFS
PTPRB_HUMAN/467-543 MATVT.SISGD........LK
PTPRB_HUMAN/907-984 QIMIA.SVSGS........LK
PTPRB_HUMAN/112-192 NIAIT.AVSGG.......KRS
PTPRB_HUMAN/1355-1434 LVSIK.VQSAG.......MTS
PTP10_DROME/583-661 TIQVN.TVSFG.......VES
PTP10_DROME/312-394 NVIVK.TVSGK.......VTS
PTP10_DROME/217-301 NISVQ.TMSED.......EIS
PTP10_DROME/123-205 QVQAY.TIYDG.......KES
EPHA2_HUMAN/329-420 TFTVE.ARNGV........SG
EPHA1_HUMAN/333-431 TFNVE.AQNGVS....GLGSS
EPHB2_CHICK/326-422 TFEIQ.AVNGVTD...QSPFS
EPHA3_CHICK/325-421 TFEID.AVNGVSD...LSTLS
PTP10_DROME/864-944 TFTVV.VRSGTES..SVLRSS
PTPRB_HUMAN/1261-1344 QFNVK.TVSGDS....WKTYS
TIE1_HUMAN/545-632 QLDVQ.LYHCTL....LGPAS
7LESS_DROME/1799-1891 SLWVQ.AHATPT....KSNSS
PHB_ALCFA/344-418 SYTVT.AVDPTAG...ESQPS
APU_THETY/928-1009 VYAVT.AVDNDGN...ESALS
CHIT_STRLI/142-219 SYSVK.ARDTADQ...TGPAS
CHIA1_BACCI/465-542 TFTIK.AKDAAGN...LSAAS
GUNB_CELFI/651-733 SYVVK.AKDVAGN...VSAAS
CHIX_STROI/169-240 AFQVA.AVNGA.......GES
APU_THETY/1165-1248 YYKVV.AVDTSY....NRTAS
KALM_CHICK/177-269 QFRVA.AVNVHG....TRGFT
CNTN1_CHICK/799-884 HIDVS.AFNSAG....YGPPS
CNTN2_CHICK/807-896 HVSVR.AYNRAG....AGPPS
NRG_DROME/815-905 YARIL.AYNGRF....NGPPS
L1CAM_HUMAN/812-907 HLEVQ.AFNGRG....SGPAS
LAR_DROME/709-800 SIQVA.ALTRKG....DGDRS
PTP99_DROME/171-259 RVIVK.AFTTKN....EGEPS
EPHA2_HUMAN/436-519 LVQVQ.ALTQEG....QGAGS
LAR_DROME/909-995 IFRVR.AYTKQG....AGPFS
NRCAM_CHICK/928-1014 KFYFN.AQTSV......GSGS
EPHB2_CHICK/437-521 VFQVR.ARTVAG....YGRYS
EPHA4_MOUSE/441-525 VFHVR.ARTAAG....YGDFS
ITB4_HUMAN/1220-1310 RYTVK.ARNGAG....WGPER
#=GR ITB4_HUMAN/1220-1310 SS EEEEE.EEETTE....E--BE
ITB4_HUMAN/1641-1728 KFKVQ.ARTTEG....FGPER
ITB4_HUMAN/1528-1612 VFRVR.AQSQEG....WGRER
#=GC SS_cons EEEEE.EEETTE....E-EBE
#=GC seq_cons phpVt.Ahsst.......t.S
//
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