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|
# STOCKHOLM 1.0
#=GF ID Pkinase
#=GF AC PF00069.24
#=GF DE Protein kinase domain
#=GF PI pkinase;
#=GF AU Sonnhammer ELL
#=GF SE Unknown
#=GF GA 27.00 27.00;
#=GF TC 27.00 27.00;
#=GF NC 26.90 26.90;
#=GF BM hmmbuild HMM.ann SEED.ann
#=GF SM hmmsearch -Z 26740544 -E 1000 --cpu 4 HMM pfamseq
#=GF TP Domain
#=GF WK Protein_kinase_domain
#=GF RN [1]
#=GF RM 1956325
#=GF RT Protein kinase catalytic domain sequence database:
#=GF RT identification of conserved features of primary structure and
#=GF RT classification of family members.
#=GF RA Hanks SK, Quinn AM;
#=GF RL Methods Enzymol 1991;200:38-62.
#=GF RN [2]
#=GF RM 7768349
#=GF RT Protein kinases 6. The eukaryotic protein kinase superfamily:
#=GF RT kinase (catalytic) domain structure and classification.
#=GF RA Hanks SK, Hunter T;
#=GF RL FASEB J 1995;9:576-596.
#=GF RN [3]
#=GF RM 9020587
#=GF RT The protein kinases of budding yeast: six score and more.
#=GF RA Hunter T, Plowman GD;
#=GF RL Trends Biochem Sci 1997;22:18-22.
#=GF DR INTERPRO; IPR000719;
#=GF DR PROSITE; PDOC00100;
#=GF DR PROSITE; PDOC00212;
#=GF DR PROSITE; PDOC00213;
#=GF DR PROSITE; PDOC00629;
#=GF DR PROSITE_PROFILE; PS50011;
#=GF DR PRINTS; PR00109;
#=GF DR SMART; STYKc;
#=GF DC Protein kinase; unclassified specificity.
#=GF DR SMART; S_TKc;
#=GF DC Serine/Threonine protein kinases, catalytic domain
#=GF DR SMART; TyrKc;
#=GF DC Tyrosine kinase, catalytic domain
#=GF DR SCOP; 1apm; sf;
#=GF DR HOMSTRAD; kinase;
#=GF DR HOMSTRAD; TyrKc;
#=GF SQ 38
#=GS CDC15_YEAST/25-272 AC P27636.3
#=GS BYR2_SCHPO/394-658 AC P28829.1
#=GS STE20_YEAST/620-871 AC Q03497.1
#=GS MKK1_YEAST/221-488 AC P32490.1
#=GS STE7_YEAST/191-466 AC P06784.1
#=GS BYR1_SCHPO/66-320 AC P10506.1
#=GS M3K9_HUMAN/144-403 AC P80192.3
#=GS M3K9_HUMAN/144-403 DR PDB; 3DTC A; 144-403;
#=GS M3K9_HUMAN/144-403 DR PDB; 4UY9 A; 144-403;
#=GS M3K9_HUMAN/144-403 DR PDB; 4UY9 B; 144-403;
#=GS F7CJC0_CALJA/134-393 AC F7CJC0.1
#=GS KPRO_MAIZE/534-810 AC P17801.2
#=GS TTK_HUMAN/525-791 AC P33981.2
#=GS TTK_HUMAN/525-791 DR PDB; 5EH0 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4BI2 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4JT3 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 2X9E A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4O6L A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4D2S A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EI6 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3H9F A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3WYY A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 2ZMC A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4J A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4CV8 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3WZJ A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP6 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3WZK A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3WYX A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP5 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4BHZ A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3HMO A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP3 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3HMP A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4JS8 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4BI0 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3DBQ A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3W1F A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4I A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3CEK A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3VQU A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4O6L B; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EI8 A; 525-753;
#=GS TTK_HUMAN/525-791 DR PDB; 4CVA A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4BI1 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 2ZMD A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP4 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP7 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EHY A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EHL A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4E A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4H A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4G A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP1 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4CV9 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3GFW A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 3HMN A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP0 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4C4F A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5AP2 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5LJJ A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EI2 A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 4ZEG A; 525-791;
#=GS TTK_HUMAN/525-791 DR PDB; 5EHO A; 525-791;
#=GS WEE1_HUMAN/299-569 AC P30291.2
#=GS WEE1_HUMAN/299-569 DR PDB; 2IN6 A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 3BI6 A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 1X8B A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 3CR0 A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 2IO6 A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 3CQE A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 2Z2W A; 299-569;
#=GS WEE1_HUMAN/299-569 DR PDB; 3BIZ A; 299-569;
#=GS CSK21_CHICK/39-324 AC P21868.1
#=GS BUR1_YEAST/60-366 AC P23293.1
#=GS CTK1_YEAST/183-469 AC Q03957.1
#=GS KIN28_YEAST/7-290 AC P06242.1
#=GS I1MG96_SOYBN/4-287 AC I1MG96.1
#=GS CDKL1_HUMAN/4-287 AC Q00532.5
#=GS CDKL1_HUMAN/4-287 DR PDB; 4AGU B; 4-287;
#=GS CDKL1_HUMAN/4-287 DR PDB; 4AGU C; 4-287;
#=GS CDKL1_HUMAN/4-287 DR PDB; 4AGU A; 4-287;
#=GS MAK_RAT/4-284 AC P20793.2
#=GS GSK3A_RAT/119-403 AC P18265.1
#=GS MK04_HUMAN/20-312 AC P31152.2
#=GS PIM1_HUMAN/129-381 AC P11309.3
#=GS PIM1_HUMAN/129-381 DR PDB; 3JXW A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXU A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5IPJ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4MED A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4ALW A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3BWF A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4LMU A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3UMW A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3CXW A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5KZI A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4JX3 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3MA3 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5DGZ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3R01 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XJ2 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4K18 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2J2I B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4IAA A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4RC2 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBQ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4N6Z A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YWV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BZI B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4ENY A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4GW8 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3DCV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2O3P A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4AS0 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4MTA A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5DHJ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3C4E B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXU D; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3JYA A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3UMX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4ENX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4MBL A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4BZN A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XJ0 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BIL B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBW A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2OI4 X; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3CY3 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2OBJ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YI4 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3C4E D; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2C3I B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XJ1 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3R02 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BIK B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5DWR A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YHS A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3WE8 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5C1Q B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4XHK B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXS A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BZK B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4RPV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3C4E A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3JY0 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4N70 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3R00 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BZJ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1XR1 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5EOL A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4DTK A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4XH6 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1XQZ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XIX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3QF9 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XIY A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXU B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4RC3 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4N6Y A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXT A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2XIZ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4MBI A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3CY2 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4ALV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4A7C A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBT A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3BGP A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4WRS A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2BZH B; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3BGZ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3BGQ A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3R04 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2O64 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YI3 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3JPV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBV A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4WT6 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4TY1 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5IIS A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3UIX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4I41 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1XWS A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4WSY A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4BZO A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBX A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4JX7 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 5DIA A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4LM5 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4LL5 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4RC4 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VBY A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3T9I A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4RBL A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 1YXU C; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4ALU A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3VC4 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2O65 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4K1B A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3F2A A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 4K0Y A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3C4E C; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 2O63 A; 38-290;
#=GS PIM1_HUMAN/129-381 DR PDB; 3A99 A; 38-290;
#=GS PSK1_YEAST/1096-1354 AC P31374.2
#=GS CDC5_YEAST/82-337 AC P32562.1
#=GS AKT1_HUMAN/150-408 AC P31749.2
#=GS AKT1_HUMAN/150-408 DR PDB; 4EKK A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 4EKK B; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3OCB B; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 4EJN A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3QKM A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3OCB A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3MV5 A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3MVH A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 4GV1 A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3O96 A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3OW4 B; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 4EKL A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 5KCV A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3CQW A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3CQU A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3QKK A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3OW4 A; 150-408;
#=GS AKT1_HUMAN/150-408 DR PDB; 3QKL A; 150-408;
#=GS ARBK1_BOVIN/191-453 AC P21146.1
#=GS ARBK1_BOVIN/191-453 DR PDB; 3UZT A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 3UZS A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 1YM7 B; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 3PVU A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 1OMW A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 1YM7 A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 3PSC A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 1YM7 D; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 3PVW A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 5HE3 A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 5HE2 A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 1YM7 C; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 5HE0 A; 191-453;
#=GS ARBK1_BOVIN/191-453 DR PDB; 2BCJ A; 191-453;
#=GS KIN82_YEAST/324-602 AC P25341.3
#=GS PKD1_DICDI/334-589 AC P34100.2
#=GS KGP1_DROME/457-717 AC Q03042.2
#=GS RAD53_YEAST/198-466 AC P22216.1
#=GS RAD53_YEAST/198-466 DR PDB; 4PDS B; 199-466;
#=GS RAD53_YEAST/198-466 DR PDB; 4PDP A; 199-466;
#=GS RAD53_YEAST/198-466 DR PDB; 4PDS A; 199-466;
#=GS RAD53_YEAST/198-466 DR PDB; 4PDP B; 199-466;
#=GS CDR1_SCHPO/12-258 AC P07334.3
#=GS KS6A1_MOUSE/407-664 AC P18653.1
#=GS PHKG2_RAT/24-291 AC P31325.1
#=GS KCC4_MOUSE/42-296 AC P08414.2
#=GS MYLK_CHICK/1453-1708 AC P11799.2
#=GS CDPK_SOYBN/34-292 AC P28583.1
#=GS Q8I534_PLAF7/111-364 AC Q8I534.1
#=GS CHK1_SCHPO/10-272 AC P34208.2
#=GS FUSED_DROME/4-254 AC P23647.2
CDC15_YEAST/25-272 YHLKQVIGRGSYGVV..YKAINKHTDQVVAIKEVVYENDEELND........IMAEISLLKNLN...HNNIVKYHGFIRK.............SYELY..ILLEYCANGS....LRRLIS.......RSSTGLSEN.......ESK.TYVTQTLLGLKYLH.GEG...VIHRDIKAANILLS............ADN.......TVKLADFGVSTIVNSS.....................ALTLAGTLNWMAPEIL..........GN...RGA.STLSDIWSLGATVVEMLTKNPPYHNLTDANIYYAVEND.........................TYYPPSSF....................................SEPLKDFLSKCFVKNMYKRPT.....ADQLLKHVWI
#=GR CDC15_YEAST/25-272 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CDC15_YEAST/25-272 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
BYR2_SCHPO/394-658 WIRGALIGSGSFGQV..YLGMNASSGELMAVKQVILDSVSESKDRHAKLLDALAGEIALLQELS...HEHIVQYLGSNLN.............SDHLN..IFLEYVPGGS....VAGLLTM....YG...S.FEET.......LVK.NFIKQTLKGLEYLH.SRG...IVHRDIKGANILVD.N..........KGK........IKISDFGISKKLELNSTSTK............TGGARPSFQGSSFWMAPEVV..........KQ...TMH.TEKTDIWSLGCLVIEMLTSKHPYP..........NCDQ..MQAIFRI............GENILPEFPSNI....................................SSSAIDFLEKTFAIDCNLRPT.....ASELLSHPFV
#=GR BYR2_SCHPO/394-658 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR BYR2_SCHPO/394-658 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
STE20_YEAST/620-871 YANLVKIGQGASGGV..YTAYEIGTNVSVAIKQMNLEKQPKKEL........IINEILVMKGSK...HPNIVNFIDSYVL.............KGDLW..VIMEYMEGGS....LTDVV........THCI.LTEG.......QIG.AVCRETLSGLEFLH.SKG...VLHRDIKSDNILLS.M..........EGD........IKLTDFGFCAQINELNL..................KRTTMVGTPYWMAPEVV..........SR...KEY.GPKVDIWSLGIMIIEMIEGEPPYL............NETPLRALYLIAT..........NGTPKLKEPENL....................................SSSLKKFLDWCLCVEPEDRAS.....ATELLHDEYI
#=GR STE20_YEAST/620-871 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR STE20_YEAST/620-871 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
MKK1_YEAST/221-488 IETLGILGEGAGGSV..SKCKLKNGSKIFALKVINTLNTDPEYQ......KQIFRELQFNRSFQ...SEYIVRYYGMFTDD...........ENSSIY..IAMEYMGGRSLDAIYKNLLE.......RGGR.ISEK.......VLG.KIAEAVLRGLSYLH.EKK...VIHRDIKPQNILLN.E..........NGQ........VKLCDFGVSGEAVNSL....................ATTFTGTSFYMAPERI..........QG...QPY.SVTSDVWSLGLTILEVANGKFPCS....SEKMAANIAP..FELLMWILT.........FTPELKDEPESNII..................................WSPSFKSFIDYCLKKDSRERPS.....PRQMINHPWI
#=GR MKK1_YEAST/221-488 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR MKK1_YEAST/221-488 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
STE7_YEAST/191-466 LVQLGKIGAGNSGTV..VKALHVPDSKIVAKKTIPVEQNNSTII......NQLVRELSIVKNVK..PHENIITFYGAYYNQ..........HINNEII..ILMEYSDCGS....LDKILSVYK.RFVQRGT.VSSKKTWFNELTIS.KIAYGVLNGLDHLYRQYK...IIHRDIKPSNVLIN.S..........KGQ........IKLCDFGVSKKLINSI....................ADTFVGTSTYMSPERI..........QG...NVY.SIKGDVWSLGLMIIELVTGEFPLGGHNDTPDGILDLLQ..........R..........IVNEPSPRLPKDR.................................IYSKEMTDFVNRCCIKNERERSS.....IHELLHHDLI
#=GR STE7_YEAST/191-466 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR STE7_YEAST/191-466 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
BYR1_SCHPO/66-320 LEVVRHLGEGNGGAV..SLVK..HRNIFMARKTVYVGSDSKLQ.......KQILRELGVLHHCR...SPYIVGFYGAFQY.............KNNIS..LCMEYMDCGS....LDAILR.......EGGP.IPLD.......ILG.KIINSMVKGLIYLYNVLH...IIHRDLKPSNVVVN.S..........RGE........IKLCDFGVSGELVNSV....................AQTFVGTSTYMSPERI..........RG...GKY.TVKSDIWSLGISIIELATQELPWS........FSNIDD..SIGILDLLH.........CIVQEEPPRLPSS...................................FPEDLRLFVDACLHKDPTLRAS.....PQQLCAMPYF
#=GR BYR1_SCHPO/66-320 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR BYR1_SCHPO/66-320 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
M3K9_HUMAN/144-403 LTLEEIIGIGGFGKV..YRAF..WIGDEVAVKAARHDPDEDISQT....IENVRQEAKLFAMLK...HPNIIALRGVCLK.............EPNLC..LVMEFARGGP....LNRVLSG....KR.....IPPD.......ILV.NWAVQIARGMNYLH.DEAIVPIIHRDLKSSNILILQ...........KVENGDLSNKILKITDFGLAREWHRTT....................KMSAAGTYAWMAPEVI..........RA...SMF.SKGSDVWSYGVLLWELLTGEVPFRGIDGLAVAYGVAMN.......................KLALPIPSTC....................................PEPFAKLMEDCWNPDPHSRPS.....FTNILDQ..L
#=GR M3K9_HUMAN/144-403 SS EEEEEEEEECSSEEE..EEEE..ETTEEEEEEEE---TTS-HHHH....HHHHHHHHHHHTT--...-TTB--EEEEE-S.............TT--E..EEEE--TTEE....HHHHHHH....S-.....--HH.......HHH.HHHHHHHHHHHHHH.HTSSS----S--SGGGEEESS...........--GGG--SS--EEE-----SGGG---C....................CC--SSGGGGS-HHHH..........HH...---.SHHHHHHHHHHHHHHHHH---TTTTS-HHHHHHHHHTT.......................-------TTS....................................-TTHHHHHHHHT-SSGGGS--.....HHHHHHH..H
#=GR M3K9_HUMAN/144-403 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR M3K9_HUMAN/144-403 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
F7CJC0_CALJA/134-393 VMLSTRIGSGSFGTV..YKGK...WHGDVAVKILKVVDPTPEQF......QAFRNEVAVLRKTR...HVNILLFMGYMT..............KDNLA..IVTQWCEGSS....LYKHLH......VQETK.FQMF.......QLI.DIARQTAQGMDYLH.AKN...IIHRDMKSNNIFLH............EGL.......TVKIGDFGLATVKSRWSGS................QQVEQPTGSVLWMAPEVI..........RMQDNNPF.SFQSDVYSYGIVLYELMTGELPYSHINNRDQIIFMVGR.......................GYASPDLSKLYK................................NCPKAMKRLVADCVKKVKEERPL.....FPQILSSIEL
#=GR F7CJC0_CALJA/134-393 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
KPRO_MAIZE/534-810 RKFKVELGRGESGTV..YKGV.LEDDRHVAVKKLENVRQGK.........EVFQAELSVIGRIN...HMNLVRIWGFCSE.............GSHRL..LVSEYVENGS....LANIL.............FSEGGNILLDWEGRFNIALGVAKGLAYLH.HECLEWVIHCDVKPENILLD............QAF.......EPKITDFGLVKLLNRGGST................QNVSHVRGTLGYIAPEWV..........SS...LPI.TAKVDVYSYGVVLLELLTGTRVSELVGGTDEVHSMLRKLVRMLSAKLEGEEQSWIDGYLDSKLNRPVNYVQ....................................ARTLIKLAVSCLEEDRSKRPT.....MEHAVQ....
#=GR KPRO_MAIZE/534-810 pAS ............................................................................................................................................................................*....................................*.................................................................................................................................................................................................................
TTK_HUMAN/525-791 YSILKQIGSGGSSKV..FQVLN.EKKQIYAIKYVNLEEADNQTL......DSYRNEIAYLNKLQQ.HSDKIIRLYDYEIT.............DQYIY..MVMECGNID.....LNSWLK.......KKKS.IDPW.......ERK.SYWKNMLEAVHTIH.QHG...IVHSDLKPANFLIV............DGM........LKLIDFGIANQMQPDTTS................VVKDSQVGTVNYMPPEAIKDMSSSRENGKS...KSKISPKSDVWSLGCILYYMTYGKTPFQQIINQISKLHAIID.................................PNHEI.........................EFPDIPEKDLQDVLKCCLKRDPKQRIS.....IPELLAHPYV
#=GR TTK_HUMAN/525-791 SS EEEEEEEEEESSEEE..EEEEE.TTSBEEEEEEEECTT--HHHH......HHHHHHHHHHHHHTT.T-TTB--EEEEEE-.............SSEEE..EEEE--SEE.....HHHHHH.......HCSS.--HH.......HHH.HHHHHHHHHHHHHH.HTT...---SS--GGGEEEE............TTE........EEE-S-SSSTT-EE--SS................----TTTSTSTT--HHHHHTTT--------...----SHHHHHHHHHHHHHHHHHSS-TTTT--SHHHHHHHHHS.................................TTS--.........................-----S-HHHHHHHHHHT-SSTTTS--.....HHHHTTSHHH
#=GR TTK_HUMAN/525-791 pAS ............................................................................................................................................................................*....................................*.................................................................................................................................................................................................................
WEE1_HUMAN/299-569 FHELEKIGSGEFGSV..FKCVKRLDGCIYAIKRSKKPLAGSVDE......QNALREVYAHAVLG..QHSHVVRYFSAWAE.............DDHML..IQNEYCNGGS....LADAISE....NYRIMSYFKEA.......ELK.DLLLQVGRGLRYIH.SMS...LVHMDIKPSNIFISRTSIPNAASEEGDEDDWASNKVMFKIGDLGHVTRISS......................PQVEEGDSRFLANEVL..........QE...NYTHLPKADIFALALTVVCA.AGAEPLP...RNGDQWHEIRQGRLPRIPQVL...........................................................SQEFTELLKVMIHPDPERRPS.....AMALVKHSVL
#=GR WEE1_HUMAN/299-569 SS EEEEEEEEEESSEEE..EEEEETTTTEEEEEEEEE---TTSHHH......HHHHHHHHHHHHS-..S-TTB--EEEEEEE.............TTEEE..EEEE--TT-B....HHHHHHH....HHHHT----HH.......HHH.HHHHHHHHHHHHHH.HTT...EE-S--SGGGEEEE----------------------EEEE--GTT-EETT-......................SS-----GGG--HHHH..........TT...--TTTHHHHHHHHHHHHHHH.TT-----...SSCHHHHHHHTT-----SS--...........................................................-HHHHHHHHHHT-SSGGGS--.....HHHHHT-TTH
#=GR WEE1_HUMAN/299-569 pAS ............................................................................................................................................................................*....................................*.................................................................................................................................................................................................................
CSK21_CHICK/39-324 YQLVRKLGRGKYSEV..FEAINITNNEKVVVKILKPVKKKKIKR...........EIKILENLR..GGPNIITLADIVKD.............PVSRTPALVFEHVNNTD....FKQLYQ..........T.LTDY.......DIR.FYMYEILKALDYCH.SMG...IMHRDVKPHNVMIDHE..........HRK........LRLIDWGLAEFYHPGQE...................YNVRVASRYFKGPELL.........VDY...QMY.DYSLDMWSLGCMLASMIFRKEPFFHGHD......NYDQ..LVRIAKVLGTEDLYDYIDKYNIELDPRFNDILGRHSRKRWE...............RFVHSENQHLVSPEALDFLDKLLRYDHQSRLT.....AREAMEHPYF
#=GR CSK21_CHICK/39-324 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CSK21_CHICK/39-324 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
BUR1_YEAST/60-366 YREDEKLGQGTFGEV..YKGIHLETQRQVAMKKIIVSVEKDLFP......ITAQREITILKRLN...HKNIIKLIEMVYDHSPDITNAASSNLHKSFY..MILPYMVADLSGVLHNPRIN............LEMC.......DIK.NMMLQILEGLNYIH.CAK...FMHRDIKTANILID.H..........NGV........LKLADFGLARLYYGCPPNLKYPG......GAGSGAKYTSVVVTRWYRAPELV.........LGD...KQY.TTAVDIWGVGCVFAEFFEKKPILQ...GKT....DIDQ..GHVIFKLLG.........TPTEEDWAVARYLPGAELTTTNYK..............PTLRERFGKYLSETGLDFLGQLLALDPYKRLT.....AMSAKHHPWF
#=GR BUR1_YEAST/60-366 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR BUR1_YEAST/60-366 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
CTK1_YEAST/183-469 YLRIMQVGEGTYGKV..YKAKNTNTEKLVALKKLRLQGEREGFP......ITSIREIKLLQSFD...HPNVSTIKEIMVE............SQKTVY..MIFEYADNDLSGLLLNKEVQ............ISHS.......QCK.HLFKQLLLGMEYLH.DNK...ILHRDVKGSNILID.N..........QGN........LKITDFGLARKMNSRAD...................YTNRVITLWYRPPELL.........LGT...TNY.GTEVDMWGCGCLLVELFNKTAIFQ...GSN....ELEQ..IESIFKIMG.........TPTINSWPTLYDMPWFFMIMPQQTTK.........YVNNFSEKFKSVLPSSKCLQLAINLLCYDQTKRFS.....ATEALQSDYF
#=GR CTK1_YEAST/183-469 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CTK1_YEAST/183-469 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
KIN28_YEAST/7-290 YTKEKKVGEGTYAVV..YLGCQHSTGRKIAIKEIKTSEFKDGLD......MSAIREVKYLQEMQ...HPNVIELIDIFMA.............YDNLN..LVLEFLP........TDLEVVI...KDKSIL.FTPA.......DIK.AWMLMTLRGVYHCH.RNF...ILHRDLKPNNLLFS.P..........DGQ........IKVADFGLARAIPAPHE..................ILTSNVVTRWYRAPELL.........FGA...KHY.TSAIDIWSVGVIFAELMLRIPYLP...GQN....DVDQ..MEVTFRALG.........TPTDRDWPEVSSFMTYNKLQIYPPP............SRDELRKRFIAASEYALDFMCGMLTMNPQKRWT.....AVQCLESDYF
#=GR KIN28_YEAST/7-290 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR KIN28_YEAST/7-290 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
I1MG96_SOYBN/4-287 YEKVEKIGEGTYGVV..YKARDRVTNETIALKKIRLEQEDEGVP......STAIREISLLKEMQ...HRNIVRLQDVVHS.............EKRLY..LVFEYLD........LDLKKHM..DSSPEFV.KDPR.......QVK.MFLYQILCGIAYCH.SHR...VLHRDLKPQNLLIDRR..........TNS........LKLADFGLARAFGIPVR..................TFTHEVVTLWYRAPEIL.........LGS...RHY.STPVDVWSVGCIFAEMVNRRPLFP...GDS....EIDE..LFKIFRILG.........TPNEDTWPGVTSLPDFKSTFPKWP..............SKDLANVVPNLDAAGLNLLSSMLCLDPSKRIT.....ARSAVEHEYF
#=GR I1MG96_SOYBN/4-287 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
CDKL1_HUMAN/4-287 YEKIGKIGEGSYGVV..FKCRNRDTGQIVAIKKFLESEDDPVIK......KIALREIRMLKQLK...HPNLVNLLEVFRR.............KRRLH..LVFEYCDHTV....LHELDRYQ...RG.....VPEH.......LVK.SITWQTLQAVNFCH.KHN...CIHRDVKPENILIT.K..........HSV........IKLCDFGFARLLAGPSD..................YYTDYVATRWYRSPELL.........VGD...TQY.GPPVDVWAIGCVFAELLSGVPLWP...GKS....DVDQ..LYLIRKTLG..........D..........LIPRHQQVFSTNQYFSGV.KIPDPEDMEPLELKFPNISYPALGLLKGCLHMDPTQRLT.....CEQLLHHPYF
#=GR CDKL1_HUMAN/4-287 SS EEEEEEEEE-SSEEE..EEEEETTT--EEEEEEE---SS-HHHH......HHHHHHHHHHHH--...-TTB--EEEEEEE.............TTEEE..EEEE--SEEH....HHHHHHTS...S-.....--HH.......HHH.HHHHHHHHHHHHHH.HTT...EE----SGGGEEE-.T..........TS-........EEE---TT-EE------..................--------GGG--HHHH.........TT-...S--.-THHHHHHHHHHHHHHHHSS-S--...-SS....HHHH..HHHHHHHH-..........S..........--HHHHHHHHT-GGGTT-.-----SS---HHHH-TTS-HHHHHHHHHH--SSTTTS--.....HHHHTTSGGG
#=GR CDKL1_HUMAN/4-287 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CDKL1_HUMAN/4-287 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
MAK_RAT/4-284 YTTMRQLGDGTYGSV..LMGKSNESGELVAIKRMKRKFYSWDECMN..LR.....EVKSLKKLN...HANVIKLKEVIRE.............NDHLY..FIFEYMK........ENLYQLM...KDRNKL.FPES.......VIR.NIMYQILQGLAFIH.KHG...FFHRDMKPENLLCM.G..........PEL........VKIADFGLARELRSQPP...................YTDYVSTRWYRAPEVL.........LRS...SVY.SSPIDVWAVGSIMAELYTFRPLFP...GTS....EVDE..IFKICQVLG.........TPKKSDWPEGYQLASSMNFRFPQC.............IPINLKTLIPNASSEAIQLMTEMLNWDPKKRPT.....ASQALKHPYF
#=GR MAK_RAT/4-284 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR MAK_RAT/4-284 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
GSK3A_RAT/119-403 YTDIKVIGNGSFGVV..YQARLAETRELVAIKKVLQDKRFKNR............ELQIMRKLD...HCNIVRLRYFFYSSG.........EKKDELYLNLVLEYVP........ETVYRVARHFTKAKLI.IPII.......YVK.VYMYQLFRSLAYIH.SQG...VCHRDIKPQNLLVDPD..........TAV........LKLCDFGSAKQLVRGEP...................NVSYICSRYYRAPELI.........FGA...TDY.TSSIDVWSAGCVLAELLLGQPIFP...GDS....GVDQ..LVEIIKVLG..........T.....PTREQIREMNPNYTEFKFPQ........IKAHPWTKVFKSRTPPEAIALCSSLLEYTPSSRLS.....PLEACAHSFF
#=GR GSK3A_RAT/119-403 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR GSK3A_RAT/119-403 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
MK04_HUMAN/20-312 FVDFQPLGFGVNGLV..LSAVDSRACRKVAVKKIALSDARSMKH........ALREIKIIRRLD...HDNIVKVYEVLGPKGTDL..QGELFKFSVAY..IVQEYMETD.....LARLLEQ....GT.....LAEE.......HAK.LFMYQLLRGLKYIH.SAN...VLHRDLKPANIFISTE..........DLV........LKIGDFGLARIVDQHYSHK...............GYLSEGLVTKWYRSPRLL.........LSP...NNY.TKAIDMWAAGCILAEMLTGRMLFA..........GAHE..LEQMQLILE..........T..........IPVIREEDKDELLRVMPSFVSSTWEVKRPLRKLLPEVNSEAIDFLEKILTFNPMDRLT.....AEMGLQHPYM
#=GR MK04_HUMAN/20-312 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR MK04_HUMAN/20-312 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
PIM1_HUMAN/129-381 YQVGPLLGSGGFGSV..YSGIRVSDNLPVAIKHVEKDRISDWGELP..NGTRVPMEVVLLKKVSS.GFSGVIRLLDWFER.............PDSFV..LILERPEPVQ...DLFDFIT.......ERGA.LQEE.......LAR.SFFWQVLEAVRHCH.NCG...VLHRDIKDENILIDLN..........RGE........LKLIDFGSGALLKDTV....................YTDFDGTRVYSPPEWI..........RY...HRYHGRSAAVWSLGILLYDMVCGDIPFEHDEEIIRGQVFFRQRV...................................................................SSECQHLIRWCLALRPSDRPT.....FEEIQNHPWM
#=GR PIM1_HUMAN/129-381 SS EEEEEEEEEETTEEE..EEEEETTTTEEEEEEEEEGGG-SSEEEET..TSEEEEHHHHHHHHHHS.SSTTB--EEEEEEE.............SSEEE..EEEE--SSEE...EHHHHHH.......HHSS.--HH.......HHH.HHHHHHHHHHHHHH.HTT...EE-S--SGGGEEEETT..........TTE........EEE--GTT-EE--SS-....................B----S-GGGS-HHHH..........HH...S-B-HHHHHHHHHHHHHHHHHHSS-S-SSHHHHHHT----SS--...................................................................-HHHHHHHHHHT-SSGGGS--.....HHHHHTSGGG
#=GR PIM1_HUMAN/129-381 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR PIM1_HUMAN/129-381 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
PSK1_YEAST/1096-1354 FVSLQKMGEGAYGKV..NLCIHKKNRYIVVIKMIFKERILVDTWVRDRKLGTIPSEIQIMATLNKKPHENILRLLDFFED.............DDYYY...IETPVHGETGCIDLFDLIE.......FKTN.MTEF.......EAK.LIFKQVVAGIKHLH.DQG...IVHRDIKDENVIVD.S..........KGF........VKIIDFGSAAYVKSGP....................FDVFVGTIDYAAPEVL..........GG...NPYEGQPQDIWAIGILLYTVVFKENPFY..........NIDE..IL.................EGDLKFNNAEEV....................................SEDCIELIKSILNRCVPKRPT.....IDDINNDKWL
#=GR PSK1_YEAST/1096-1354 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR PSK1_YEAST/1096-1354 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
CDC5_YEAST/82-337 YHRGHFLGEGGFARC..FQIKD.DSGEIFAAKTVAKASIKSEKT.....RKKLLSEIQIHKSMS...HPNIVQFIDCFED.............DSNVY..ILLEICPNGS....LMELLK.......RRKV.LTEP.......EVR.FFTTQICGAIKYMH.SRR...VIHRDLKLGNIFFD............SNY.......NLKIGDFGLAAVLANESE..................RKYTICGTPNYIAPEVLM........GKH...SGH.SFEVDIWSLGVMLYALLIGKPPFQARDVNTIYERIKCR.......................DFSFPRDKPI....................................SDEGKILIRDILSLDPIERPS.....LTEIMDYVWF
#=GR CDC5_YEAST/82-337 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CDC5_YEAST/82-337 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
AKT1_HUMAN/150-408 FEYLKLLGKGTFGKV..ILVKEKATGRYYAMKILKKEVIVAKDE.....VAHTLTENRVLQNSR...HPFLTALKYSFQT.............HDRLC..FVMEYANGGE....LFFHLS.......RERV.FSED.......RAR.FYGAEIVSALDYLHSEKN...VVYRDLKLENLMLD.K..........DGH........IKITDFGLCKEGIKDGA..................TMKTFCGTPEYLAPEVL..........ED...NDY.GRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILME.........................EIRFPRTL....................................GPEAKSLLSGLLKKDPKQRLGGGSEDAKEIMQHRFF
#=GR AKT1_HUMAN/150-408 SS EEEEEEEEEETTEEE..EEEEETTT--EEEEEEEEHHHHHHTT-.....HHHHHHHHHHHHCSS...-TTB--EEEEEEE.............SSEEE..EEEE--TTEB....HHHHHH.......HHSS.--HH.......HHH.HHHHHHHHHHHHHHHTTT...EB----SGGGEEE-.T..........TS-........EEE---TTSBCS--TT-..................-B--CEE-GGGS-HHHH..........TT...S-B.-TTHHHHHHHHHHHHHHHSS-SS--SSHHHHHHHHHHS.........................-----TTS....................................-HHHHHHHHHHT-SSTTTSTT-STTTHHHHHTSGGG
#=GR AKT1_HUMAN/150-408 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR AKT1_HUMAN/150-408 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
ARBK1_BOVIN/191-453 FSVHRIIGRGGFGEV..YGCRKADTGKMYAMKCLDKKRIKMKQG.....ETLALNERIMLSLVSTGDCPFIVCMSYAFHT.............PDKLS..FILDLMNGGD....LHYHLS.......QHGV.FSEA.......DMR.FYAAEIILGLEHMH.NRF...VVYRDLKPANILLD.E..........HGH........VRISDLGLACDFSKKK....................PHASVGTHGYMAPEVL.........QKG...VAY.DSSADWFSLGCMLFKLLRGHSPFRQHKTKDKHEIDRMT......................LTMAVELPDSF....................................SPELRSLLEGLLQRDVNRRLGCLGRGAQEVKESPFF
#=GR ARBK1_BOVIN/191-453 SS EEEEEEEEEESSEEE..EEEEETTT--EEEEEEEEHHHHHHHTT.....HHHHHHHHHHHHHHSSS--TTB--EEEEEEE.............SSEEE..EEEE--TS-B....HHHHHH.......HH-S.--HH.......HHH.HHHHHHHHHHHHHH.HTT...EE----SGGGEEE-.T..........TS-........EEE--GTT-EE-SSS-....................--S--S-TTS--HHHH.........STT...---.STHHHHHHHHHHHHHHHHSS-TT-SSTSS-HHHHHHHH......................HH------TTS....................................-HHHHHHHHHHT-SSSTTSTTTSSSTHHHHHTSGGG
#=GR ARBK1_BOVIN/191-453 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR ARBK1_BOVIN/191-453 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
KIN82_YEAST/324-602 FEKIRLLGQGDVGKV..YLVRERDTNQIFALKVLNKHEMIKRKK.....IKRVLTEQEILATSD...HPFIVTLYHSFQT.............KDYLY..LCMEYCMGGE....FFRALQ......TRKSKCIAEE.......DAK.FYASEVVAALEYLH.LLG...FIYRDLKPENILLH.Q..........SGH........VMLSDFDLSIQATGSKKPTMKDSTYLDTKICSDGFRTNSFVGTEEYLAPEVI..........RG...NGH.TAAVDWWTLGILIYEMLFGCTPFKGDNSNETFSNILTK.......................DVKFPHDKEV....................................SKNCKDLIKKLLNKNEAKRLGSK.SGAADIKRHPFF
#=GR KIN82_YEAST/324-602 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR KIN82_YEAST/324-602 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
PKD1_DICDI/334-589 FNFYGSLGSGSFGTA..KLCRHRGSGLFFCSKTLRRETIVHEKH.....KEHVNNEINIMLNIS...HPYIVKTYSTFNT.............PTKIH..FIMEYAGKKD....LFHHLR.......ANKC.FTEQ.......TTK.LIVAEIVLAIEYLH.AEN...IIYRDLKPENILID.E..........KGH........IKLTDFGFSKKTVGGKN...................TSSVCGTFDYMAPEIL.........NSS...NGH.GKPVDWWALGVVVYELVTGKLPFSNSKESLLNRKADFQLIFQNSYL.............................................................SDEIKDFIFQLLSVDPSKRLGT..FDSCSIRNHKWF
#=GR PKD1_DICDI/334-589 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR PKD1_DICDI/334-589 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
KGP1_DROME/457-717 LEVVSTLGIGGFGRVELVKAHHQDRVDIFALKCLKKRHIVDTKQ.....EEHIFSERHIMLSSR...SPFICRLYRTFRD.............EKYVY..MLLEACMGGE....IWTMLR.......DRGS.FEDN.......AAQ.FIIGCVLQAFEYLH.ARG...IIYRDLKPENLMLD.E..........RGY........VKIVDFGFAKQIGTSSK...................TWTFCGTPEYVAPEII..........LN...KGH.DRAVDYWALGILIHELLNGTPPFSAPDPMQTYNLILKG.......................IDMIAFPKHI....................................SRWAVQLIKRLCRDVPSERLGYQTGGIQDIKKHKWF
#=GR KGP1_DROME/457-717 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR KGP1_DROME/457-717 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
RAD53_YEAST/198-466 SIIDEVVGQGAFATV..KKAIERTTGKTFAVKIISKRKVIGNMD.......GVTRELEVLQKLN...HPRIVRLKGFYED.............TESYY..MVMEFVSGGD....LMDFVA.......AHGA.VGED.......AGR.EISRQILTAIKYIH.SMG...ISHRDLKPDNILIE............QDDP.....VLVKITDFGLAKVQGNGSF...................MKTFCGTLAYVAPEVIRGKDTSVSPDEYEERNEY.SSLVDMWSMGCLVYVILTGHLPFSGSTQDQLYKQIGRGSYHEGPLKDFR..........I...............................................SEEARDFIDSLLQVDPNNRST.....AAKALNHPWI
#=GR RAD53_YEAST/198-466 SS XEES--S------EE..EEEEETTT--EEEEEEE-S--------.......SHCCHHHHHCH--...-TTB--EEEEEE-.............---EE..EEEE--TT-B....HHHHHH.......HH-S.--HH.......HHH.HHHHHHHHHHHHHH.HTT...EE-S--SCCCEEEE............ETTT.....TEEEE---TT-EE------...................-------GGG--GGGC----------------TT.HHHHHHHHHHHHHHHHHHSS-SS--SSCCHHHHHHHTT---HHHHHHTT..........-...............................................-HHHHHHHHHHS-SSGGGS--.....HHHHHTSCCC
#=GR RAD53_YEAST/198-466 AS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
#=GR RAD53_YEAST/198-466 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
CDR1_SCHPO/12-258 WRLGKTLGTGSTSCV..RLAKHAKTGDLAAIKIIPIR............YASIGMEILMMRLLR...HPNILRLYDVWTD.............HQHMY..LALEYVPDGE....LFHYIR.......KHGP.LSER.......EAA.HYLSQILDAVAHCH.RFR...FRHRDLKLENILIKVN..........EQQ........IKIADFGMATVEPNDSC...................LENYCGSLHYLAPEIV..........SH...KPYRGAPADVWSCGVILYSLLSNKLPFGGQNTDVIYNKIRHG.........................AYDLPSSI....................................SSAAQDLLHRMLDVNPSTRIT.....IPEVFSHPFL
#=GR CDR1_SCHPO/12-258 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CDR1_SCHPO/12-258 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
KS6A1_MOUSE/407-664 YVVKETIGVGSYSVC..KRCVHKATNMEYAVKVIDKSKRDPSE............EIEILLRYG..QHPNIITLKDVYDD.............GKHVY..LVTELMRGGE....LLDKIL.......RQKF.FSER.......EAS.FVLHTISKTVEYLH.SQG...VVHRDLKPSNILYVDE..........SGNP.....ECLRICDFGFAKQLRAENG..................LLMTPCYTANFVAPEVL..........KR...QGY.DEGCDIWSLGILLYTMLAGYTPFANGPSDTPEEILTRI..........GS........GKFTLSGGNWNTV....................................SETAKDLVSKMLHVDPHQRLT.....AKQVLQHPWI
#=GR KS6A1_MOUSE/407-664 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR KS6A1_MOUSE/407-664 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
PHKG2_RAT/24-291 YDPKDIIGRGVSSVV..RRCVHRATGDEFAVKIMEVSAERLSLEQLEEVRDATRREMHILRQVA..GHPHIITLIDSYES.............SSFMF..LVFDLMRKGE....LFDYLT.......EKVA.LSEK.......ETR.SIMRSLLEAVNFLH.VNN...IVHRDLKPENILLD............DNM.......QIRLSDFGFSCHLEPGEK...................LRELCGTPGYLAPEILKCS....MDETH...PGY.GKEVDLWACGVILFTLLAGSPPFW..........HRRQ..ILMLRMIME.........GQYQFSSPEWDDR....................................SNTVKDLIAKLLQVDPNARLT.....AEQALQHPFF
#=GR PHKG2_RAT/24-291 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR PHKG2_RAT/24-291 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
KCC4_MOUSE/42-296 FEVESELGRGATSIV..YRCKQKGTQKPYALKVLKKTVDK..........KIVRTEIGVLLRLS...HPNIIKLKEIFET.............PTEIS..LVLELVTGGE....LFDRIV.......EKGY.YSER.......DAR.DAVKQILEAVAYLH.ENG...IVHRDLKPENLLYA............TPAPD....APLKIADFGLSKIVEHQVL...................MKTVCGTPGYCAPEIL..........RG...CAY.GPEVDMWSVGIITYILLCGFEPFYDERGD...........QFMFRRILN.........CEYYFISPWWDEV....................................SLNAKDLVKKLIVLDPKKRLT.....TFQALQHPWV
#=GR KCC4_MOUSE/42-296 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR KCC4_MOUSE/42-296 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
MYLK_CHICK/1453-1708 YNIEERLGSGKFGQV..FRLVEKKTGKVWAGKFFKAYSAKEKEN........IRDEISIMNCLH...HPKLVQCVDAFEE.............KANIV..MVLEMVSGGE....LFERII.......DEDFELTER.......ECI.KYMRQISEGVEYIH.KQG...IVHLDLKPENIMCVNK..........TGT.......SIKLIDFGLARRLESAGS...................LKVLFGTPEFVAPEVI..........NY...EPI.GYETDMWSIGVICYILVSGLSPFMGDNDNETLANVTSA.....................TWDFDDEAFDEI....................................SDDAKDFISNLLKKDMKSRLN.....CTQCLQHPWL
#=GR MYLK_CHICK/1453-1708 AS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
#=GR MYLK_CHICK/1453-1708 pAS .................................................................................................................................................................................................................*.................................................................................................................................................................................................................
CDPK_SOYBN/34-292 YEVGRKLGQGQFGTT..FECTRRASGGKFACKSIPKRKLLCKED.....YEDVWREIQIMHHLS..EHANVVRIEGTYED.............STAVH..LVMELCEGGE....LFDRIV.......QKGH.YSER.......QAA.RLIKTIVEVVEACH.SLG...VMHRDLKPENFLFD............TIDED....AKLKATDFGLSVFYKPGES...................FCDVVGSPYYVAPEVL...............RKLYGPESDVWSAGVILYILLSGVPPFWAESEPGIFRQILLG.....................KLDFHSEPWPSI....................................SDSAKDLIRKMLDQNPKTRLT.....AHEVLRHPWI
#=GR CDPK_SOYBN/34-292 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CDPK_SOYBN/34-292 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
Q8I534_PLAF7/111-364 YVLNKKIGKGSFSTA..YIGTNILYGNRVVVKEVDKSKVKE.........SNVYTEIEVLRKVM...HKYIIKLISAYEQ.............EGFVY..LVLEYLKGGE....LFEYLN.......NNGP.YTEQ.......VAK.KAMKRVLIALEALH.SNG...VVHRDLKMENLMLE............NPNDP....SSLKIIDFGLASFLNSPS....................MNMRCGSPGYVAPEIL..........KC...ASY.GTKVDIFSLGVILFNILCGYPPFRGNNVKEIFKKNMRC.....................HISFNTKHWINK....................................SESVKEIILWMCCKNPDDRCT.....ALQALGHQWF
#=GR Q8I534_PLAF7/111-364 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
CHK1_SCHPO/10-272 YHIGREIGTGAFASV..RLCY.DDNAKIYAVKFVNKKHATSCMNAG.VWARRMASEIQLHKLCN..GHKNIIHFYNTAEN.............PQWRW..VVLEFAQGGD....LFDKIE.......PDVG.IDED.......VAQ.FYFAQLMEGISFMH.SKG...VAHRDLKPENILLD.Y..........NGN........LKISDFGFASLFSYKGKS................RLLNSPVGSPPYAAPEIT...............QQYDGSKVDVWSCGIILFALLLGNTPWD....................EAISNTGDYLLYKKQCERPSYHPWNLL....................................SPGAYSIITGMLRSDPFKRYS.....VKHVVQHPWL
#=GR CHK1_SCHPO/10-272 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR CHK1_SCHPO/10-272 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
FUSED_DROME/4-254 YAVSSLVGQGSFGCV..YKATRKDDSKVVAIKVISKRGRATKEL......KNLRRECDIQARLK...HPHVIEMIESFES.............KTDLF..VVTEFALMD.....LHRYLS.......YNGA.MGEE.......PAR.RVTGHLVSALYYLH.SNR...ILHRDLKPQNVLLD............KNM.......HAKLCDFGLARNMTLGTH..................VLTSIKGTPLYMAPELL..........AE...QPY.DHHADMWSLGCIAYESMAGQPPFCASSILHLVKMIKHE.........................DVKWPSTL....................................TSECRSFLQGLLEKDPGLRIS.....WTQLLCHPFV
#=GR FUSED_DROME/4-254 pAS ...........................................................................................................................................................................*.....................................*.................................................................................................................................................................................................................
#=GR FUSED_DROME/4-254 sAS ............................................................................................................................................................................*......................................................................................................................................................................................................................................................
#=GC SS_cons EEEEEEEEEESSEEE..EEEEETTTTEEEEEEEEEHHCCCHHHHCT..THHHHHHHHHHHHHHSSSSSTTB--EEEEEEE.............SSEEE..EEEE--TTEB...EHHHHHHHS...SHHHSS.--HH.......HHH.HHHHHHHHHHHHHHHHTTSS.EE-SS-SGGGEEEETT..........TTECG..SSTEEEE-SGTTSEECCSSCSS..................BCTCCSCGGGS-HHHHHTTT-----TTT---STCTSHHHHHHHHHHHHHHHHHSS-STTTSSCHHHHHHHHHTT-HHHHHHHCT..........SHH......TTSTCCHHHHHHT.GGGTT.......SS...HHHH.TTS-HHHHHHHHHHT-SSGCCSTTTSTTTHHHHHTSGGG
#=GC seq_cons aphhpplGpGsaGsV..apshptssschhAlKtlpppphpptp.......pthhpElpllpplp...HssIlplhssaps.............pspla..llhEaspsup....Lhchlp.......ppth.hsEp.......ps+.phhtpllpulcYlH.sps...llHRDlKPpNILlc.t..........pup........lKlsDFGlAphhssss....................hsshsGT.hYhAPEll..........ps...psY.uttsDlWSlGlllh-llsGpsPFt...spt.....hpp.........................t....ppl....................................SppspcllpphLphDPpcRho.....sppllpHsah
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