File: itkMultiScaleHessianBasedMeasureImageFilter.h

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/*=========================================================================

  Program:   Insight Segmentation & Registration Toolkit
  Module:    itkMultiScaleHessianBasedMeasureImageFilter.h
  Language:  C++
  Date:      $Date$
  Version:   $Revision$

  Copyright (c) Insight Software Consortium. All rights reserved.
  See ITKCopyright.txt or http://www.itk.org/HTML/Copyright.htm for details.

     This software is distributed WITHOUT ANY WARRANTY; without even 
     the implied warranty of MERCHANTABILITY or FITNESS FOR A PARTICULAR 
     PURPOSE.  See the above copyright notices for more information.

=========================================================================*/
#ifndef __itkMultiScaleHessianBasedMeasureImageFilter_h
#define __itkMultiScaleHessianBasedMeasureImageFilter_h

#include "itkImageToImageFilter.h"
#include "itkImage.h"
#include "itkHessianRecursiveGaussianImageFilter.h"

namespace itk
{
/**\class MultiScaleHessianBasedMeasureImageFilter
 * \brief A filter to enhance structures using Hessian eigensystem-based 
 * measures in a multiscale framework
 * 
 * The filter evaluates a Hessian-based enhancement measure, such as vesselness 
 * or objectness, at different scale levels. The Hessian-based measure is computed 
 * from the Hessian image at each scale level and the best response is selected. 
 *
 * Minimum and maximum sigma value can be set using SetMinSigma and SetMaxSigma
 * methods respectively. The number of scale levels is set using 
 * SetNumberOfSigmaSteps method. Exponentially distributed scale levels are 
 * computed within the bound set by the minimum and maximum sigma values 
 * 
 * The filter computes a second output image (accessed by the GetScalesOutput method)
 * containing the scales at which each pixel gave the best reponse. 
 *
 * \author Luca Antiga Ph.D.  Medical Imaging Unit,
 *                            Bioengineering Deparment, Mario Negri Institute, Italy.
 *
 * \sa HessianToObjectnessMeasureImageFilter 
 * \sa Hessian3DToVesselnessMeasureImageFilter 
 * \sa HessianSmoothed3DToVesselnessMeasureImageFilter 
 * \sa HessianRecursiveGaussianImageFilter 
 * \sa SymmetricEigenAnalysisImageFilter
 * \sa SymmetricSecondRankTensor
 * 
 * \ingroup IntensityImageFilters TensorObjects
 *
 */
template <typename TInputImage,
          typename THessianImage, 
          typename TOutputImage=TInputImage >
class ITK_EXPORT MultiScaleHessianBasedMeasureImageFilter 
: public
ImageToImageFilter< TInputImage,TOutputImage > 
{
public:
  /** Standard class typedefs. */
  typedef MultiScaleHessianBasedMeasureImageFilter          Self;
  typedef ImageToImageFilter<TInputImage,TOutputImage>      Superclass;

  typedef SmartPointer<Self>                                      Pointer;
  typedef SmartPointer<const Self>                                ConstPointer;

  typedef TInputImage                                    InputImageType;
  typedef TOutputImage                                   OutputImageType;
  typedef THessianImage                                  HessianImageType;

  typedef ImageToImageFilter< HessianImageType, OutputImageType  >  HessianToMeasureFilterType;

  typedef typename TInputImage::PixelType                InputPixelType;
  typedef typename TOutputImage::PixelType               OutputPixelType;
  typedef typename TOutputImage::RegionType              OutputRegionType;
 
  /** Image dimension. */
  itkStaticConstMacro(ImageDimension, unsigned int, ::itk::GetImageDimension<InputImageType>::ImageDimension);

  /** Types for Scales image */
  typedef float                                          ScalesPixelType;
  typedef Image<ScalesPixelType, itkGetStaticConstMacro(ImageDimension)>  ScalesImageType;

  /** Hessian computation filter. */
  typedef HessianRecursiveGaussianImageFilter< InputImageType, HessianImageType> HessianFilterType;
 
  /** Update image buffer that holds the best objectness response. This is not redundant from
   the output image because the latter may not be of float type, which is required for the comparisons 
   between responses at different scales. */ 
  typedef Image< double, itkGetStaticConstMacro(ImageDimension) > UpdateBufferType;
  typedef typename UpdateBufferType::ValueType                    BufferValueType;
    
  typedef typename Superclass::DataObjectPointer          DataObjectPointer;
  
  /** Method for creation through the object factory. */
  itkNewMacro(Self);
  
  /** Runtime information support. */
  itkTypeMacro(MultiScaleHessianBasedMeasureImageFilter, 
                 ImageToImageFilter);
  
  /** Set/Get macros for SigmaMin */
  itkSetMacro(SigmaMinimum, double);
  itkGetConstMacro(SigmaMinimum, double);
  
  /** Set/Get macros for SigmaMax */
  itkSetMacro(SigmaMaximum, double);
  itkGetConstMacro(SigmaMaximum, double);

  /** Set/Get macros for Number of Scales */
  itkSetMacro(NumberOfSigmaSteps, unsigned int);
  itkGetConstMacro(NumberOfSigmaSteps, unsigned int);

  /** Set/Get HessianToMeasureFilter. This will be a filter that takes 
   Hessian input image and produces enhanced output scalar image. The filter must derive from 
   itk::ImageToImage filter */
  itkSetObjectMacro( HessianToMeasureFilter, HessianToMeasureFilterType); 
  itkGetObjectMacro( HessianToMeasureFilter, HessianToMeasureFilterType); 

  /** Methods to turn on/off flag to inform the filter that the Hessian-based measure
   is non-negative (classical measures like Sato's and Frangi's are), hence it has a minimum
   at zero. In this case, the update buffer is initialized at zero, and the output scale and Hessian 
   are zero in case the Hessian-based measure returns zero for all scales. Otherwise, the minimum 
   output scale and Hessian are the ones obtained at scale SigmaMinimum. On by default. 
   */
  itkSetMacro(NonNegativeHessianBasedMeasure,bool);
  itkGetConstMacro(NonNegativeHessianBasedMeasure,bool);
  itkBooleanMacro(NonNegativeHessianBasedMeasure);

  typedef enum { EquispacedSigmaSteps = 0,
                 LogarithmicSigmaSteps = 1 } SigmaStepMethodType;

  /** Set/Get the method used to generate scale sequence (Equispaced
   * or Logarithmic) */
  itkSetMacro(SigmaStepMethod, SigmaStepMethodType);
  itkGetConstMacro(SigmaStepMethod, SigmaStepMethodType);

  /**Set equispaced sigma step method */
  void SetSigmaStepMethodToEquispaced();

  /**Set logartihmic sigma step method */
  void SetSigmaStepMethodToLogarithmic();

  /** Get the image containing the Hessian computed at the best
   * response scale */
  const HessianImageType* GetHessianOutput() const;
 
  /** Get the image containing the scales at which each pixel gave the
   * best response */
  const ScalesImageType* GetScalesOutput() const;
  
  void EnlargeOutputRequestedRegion (DataObject *);

  /** Methods to turn on/off flag to generate an image with scale values at
   *  each pixel for the best vesselness response */
  itkSetMacro(GenerateScalesOutput,bool);
  itkGetConstMacro(GenerateScalesOutput,bool);
  itkBooleanMacro(GenerateScalesOutput);

  /** Methods to turn on/off flag to generate an image with hessian values at 
   *  each pixel for the best vesselness response */
  itkSetMacro(GenerateHessianOutput,bool);
  itkGetConstMacro(GenerateHessianOutput,bool);
  itkBooleanMacro(GenerateHessianOutput);

  /** This is overloaded to create the Scales and Hessian output images */
  virtual DataObjectPointer MakeOutput(unsigned int idx);

protected:
  MultiScaleHessianBasedMeasureImageFilter();
  ~MultiScaleHessianBasedMeasureImageFilter() {};
  void PrintSelf(std::ostream& os, Indent indent) const;
  
  /** Generate Data */
  void GenerateData( void );

private:
  void UpdateMaximumResponse(double sigma);
  double ComputeSigmaValue(int scaleLevel);
  
  void AllocateUpdateBuffer();

  //purposely not implemented
  MultiScaleHessianBasedMeasureImageFilter(const Self&); 
  void operator=(const Self&); //purposely not implemented

  bool                        m_NonNegativeHessianBasedMeasure;

  double                      m_SigmaMinimum;
  double                      m_SigmaMaximum;

  unsigned int                m_NumberOfSigmaSteps;
  SigmaStepMethodType         m_SigmaStepMethod;

  typename HessianToMeasureFilterType::Pointer  m_HessianToMeasureFilter;
  typename HessianFilterType::Pointer           m_HessianFilter;
  typename UpdateBufferType::Pointer            m_UpdateBuffer;

  bool m_GenerateScalesOutput;
  bool m_GenerateHessianOutput;
};

} // end namespace itk

#ifndef ITK_MANUAL_INSTANTIATION
#include "itkMultiScaleHessianBasedMeasureImageFilter.txx"
#endif
  
#endif