File: itkLabelGeometryImageFilter.h

package info (click to toggle)
insighttoolkit4 4.10.1-dfsg1-1.1
  • links: PTS, VCS
  • area: main
  • in suites: stretch
  • size: 416,780 kB
  • ctags: 104,347
  • sloc: cpp: 553,142; ansic: 142,389; fortran: 34,788; python: 16,392; lisp: 2,070; sh: 1,862; tcl: 993; java: 362; perl: 200; makefile: 111; csh: 81; pascal: 69; xml: 19; ruby: 10
file content (508 lines) | stat: -rw-r--r-- 20,209 bytes parent folder | download
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
/*=========================================================================
 *
 *  Copyright Insight Software Consortium
 *
 *  Licensed under the Apache License, Version 2.0 (the "License");
 *  you may not use this file except in compliance with the License.
 *  You may obtain a copy of the License at
 *
 *         http://www.apache.org/licenses/LICENSE-2.0.txt
 *
 *  Unless required by applicable law or agreed to in writing, software
 *  distributed under the License is distributed on an "AS IS" BASIS,
 *  WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
 *  See the License for the specific language governing permissions and
 *  limitations under the License.
 *
 *=========================================================================*/
#ifndef itkLabelGeometryImageFilter_h
#define itkLabelGeometryImageFilter_h

#include "itkImageToImageFilter.h"
#include "itkNumericTraits.h"
#include "itkArray.h"
#include "itkSimpleDataObjectDecorator.h"
#include "itksys/hash_map.hxx"
#include "itkFastMutexLock.h"
#include <vector>
#include "vnl/algo/vnl_symmetric_eigensystem.h"
#include "vnl/vnl_det.h"
#include "itkMath.h"

namespace itk
{
/** \class LabelGeometryImageFilter
 * \brief Given a label map and an optional intensity image, compute
 * geometric features.
 *
 * This filter enables the measurement of geometric features of all objects in
 * a labeled ND volume. This labeled volume can represent, for instance, a
 * medical image segmented into different anatomical structures or a microscope
 * image segmented into individual cells. This filter is closely related to the
 * itkLabelStatisticsImageFilter, which measures statistics of image regions
 * defined by a labeled mask such as min, max, and mean intensity, intensity
 * standard deviation, and bounding boxes. This filter, however, measures the
 * geometry of the labeled regions themselves.
 *
 * It calculates features similar to the regionprops command of Matlab.  The
 * set of measurements that it enables include: volume, centroid, eigenvalues,
 * eigenvectors, axes lenghts, eccentricity, elongation, orientation, bounding
 * box, oriented bounding box, and rotation matrix.  These features are based
 * solely on the labeled mask itself.  It also calculates integrated intensity
 * and weighted centroid, which are measured on an intensity image under the
 * labeled mask. These features represent the set of currently calculated
 * features, but the framework of the filter is designed so that it can be
 * easily expanded to measure a wide variety of other features.
 *
 *  \authors Dirk Padfield and James Miller.
 *
 *  This work is part of the National Alliance for Medical Image
 *  Computing (NAMIC), funded by the National Institutes of Health
 *  through the NIH Roadmap for Medical Research, Grant U54 EB005149.
 *  Information on the National Centers for Biomedical Computing
 *  can be obtained from http://commonfund.nih.gov/bioinformatics.
 *
 *  This filter was contributed in the Insight Journal paper:
 *  "A Label Geometry Image Filter for Multiple Object Measurement"
 *  by Padfield D., Miller J
 *  http://www.insight-journal.org/browse/publication/301
 *  https://hdl.handle.net/1926/1493
 *
 * \ingroup ITKReview
 *
 * \wiki
 * \wikiexample{ImageProcessing/LabelGeometryImageFilter,Get geometric properties of labeled regions in an image}
 * \endwiki
 */
template< typename TLabelImage, typename TIntensityImage = TLabelImage >
class LabelGeometryImageFilter:
  public ImageToImageFilter< TLabelImage, TIntensityImage >
{
public:
  /** Standard Self typedef */
  typedef LabelGeometryImageFilter                           Self;
  typedef ImageToImageFilter< TLabelImage, TIntensityImage > Superclass;
  typedef SmartPointer< Self >                               Pointer;
  typedef SmartPointer< const Self >                         ConstPointer;

  /** Method for creation through the object factory. */
  itkNewMacro(Self);

  /** Runtime information support. */
  itkTypeMacro(LabelGeometryImageFilter, ImageToImageFilter);

  /** Image related typedefs. */
  typedef TIntensityImage                      IntensityImageType;
  typedef typename TIntensityImage::Pointer    InputImagePointer;
  typedef typename TIntensityImage::RegionType RegionType;
  typedef typename TIntensityImage::SizeType   SizeType;
  typedef typename TIntensityImage::IndexType  IndexType;
  typedef typename TIntensityImage::PixelType  PixelType;

  /** Label image related typedefs. */
  typedef TLabelImage                      LabelImageType;
  typedef typename TLabelImage::Pointer    LabelImagePointer;
  typedef typename TLabelImage::RegionType LabelRegionType;
  typedef typename TLabelImage::SizeType   LabelSizeType;
  typedef typename TLabelImage::IndexType  LabelIndexType;
  typedef typename TLabelImage::PixelType  LabelPixelType;
  typedef typename TLabelImage::PointType  LabelPointType;

  /** Image related typedefs. */
  itkStaticConstMacro(ImageDimension, unsigned int,
                      TLabelImage::ImageDimension);

  /** Type to use for computations. */
  typedef typename NumericTraits< PixelType >::RealType RealType;

  /** Smart Pointer type to a DataObject. */
  typedef typename DataObject::Pointer DataObjectPointer;

  /** Type of DataObjects used for scalar outputs */
  typedef SimpleDataObjectDecorator< RealType > RealObjectType;

  /** Bounding Box-related typedefs */
  typedef itk::FixedArray< typename LabelIndexType::IndexValueType,
                           itkGetStaticConstMacro(ImageDimension) *2 > BoundingBoxType;
  typedef itk::FixedArray< float,
                           itkGetStaticConstMacro(ImageDimension) *2 > BoundingBoxFloatType;

  //typedef itk::FixedArray<
  // LabelPointType,std::pow(2.0,itkGetStaticConstMacro(ImageDimension))>
  // BoundingBoxVerticesType;
  typedef std::vector< LabelPointType > BoundingBoxVerticesType;

  /** Axes Length-related typedefs */
  typedef itk::FixedArray< RealType, itkGetStaticConstMacro(ImageDimension) > AxesLengthType;

  /** Index array typedefs */
  typedef itk::FixedArray< typename LabelIndexType::IndexValueType,
                           itkGetStaticConstMacro(ImageDimension) > IndexArrayType;

  /** vector of labels */
  typedef std::vector< LabelPixelType > LabelsType;

  /** vector of indices */
  typedef std::vector< LabelIndexType > LabelIndicesType;

  /** Vector type */
  typedef std::vector< double > VectorType;

  /** Matrix type */
  typedef vnl_matrix< double > MatrixType;

  /** \class LabelGeometry
   * \brief Geometry stored per label
   * \ingroup ITKReview
   */
  class LabelGeometry
  {
public:
    // default constructor
    LabelGeometry()
    {
      // initialized to the default values
      this->m_Label = 0;
      this->m_Sum = NumericTraits< RealType >::ZeroValue();

      const unsigned int imageDimension = itkGetStaticConstMacro(ImageDimension);

      //m_BoundingBox.resize(imageDimension*2);
      for ( unsigned int i = 0; i < imageDimension * 2; i += 2 )
        {
        m_BoundingBox[i] = NumericTraits< typename IndexType::IndexValueType >::max();
        m_BoundingBox[i + 1] = NumericTraits< typename IndexType::IndexValueType >::NonpositiveMin();
        }

      m_BoundingBoxVolume = 0;
      m_BoundingBoxSize.Fill(0);
      m_PixelIndices.clear();
      m_Centroid.Fill(0);
      m_WeightedCentroid.Fill(0);
      m_ZeroOrderMoment = 0;
      m_FirstOrderRawMoments.Fill(0);
      m_FirstOrderWeightedRawMoments.Fill(0);
      m_Eigenvalues.resize(ImageDimension);
      m_Eigenvalues.clear();
      m_Eigenvectors.set_size(ImageDimension, ImageDimension);
      m_Eigenvectors.fill(0);
      m_AxesLength.Fill(0);
      m_Eccentricity = 1;
      m_Elongation = 1;
      m_Orientation = 0;
      LabelPointType emptyPoint;
      emptyPoint.Fill(0);
      unsigned int numberOfVertices = 1 << ImageDimension;
      m_OrientedBoundingBoxVertices.resize(numberOfVertices, emptyPoint);
      m_OrientedBoundingBoxVolume = 0;
      m_OrientedBoundingBoxSize.Fill(0);
      m_OrientedLabelImage = LabelImageType::New();
      m_OrientedIntensityImage = IntensityImageType::New();
      m_OrientedBoundingBoxOrigin.Fill(0);
      m_RotationMatrix.set_size(ImageDimension, ImageDimension);
      m_RotationMatrix.fill(0.0);

      m_SecondOrderRawMoments.set_size(ImageDimension, ImageDimension);
      m_SecondOrderCentralMoments.set_size(ImageDimension, ImageDimension);
      for ( unsigned int i = 0; i < ImageDimension; i++ )
        {
        for ( unsigned int j = 0; j < ImageDimension; j++ )
          {
          m_SecondOrderRawMoments(i, j) = 0;
          m_SecondOrderCentralMoments(i, j) = 0;
          }
        }
    }

    LabelPixelType                                              m_Label;
    RealType                                                    m_Sum;
    LabelPointType                                              m_Centroid;
    LabelPointType                                              m_WeightedCentroid;
    SizeValueType                                               m_ZeroOrderMoment;
    IndexArrayType                                              m_FirstOrderRawMoments;
    IndexArrayType                                              m_FirstOrderWeightedRawMoments;
    SizeValueType                                               m_FirstOrderRawCrossMoment;
    RealType                                                    m_FirstOrderCentralCrossMoment;
    MatrixType                                                  m_SecondOrderRawMoments;
    MatrixType                                                  m_SecondOrderCentralMoments;
    VectorType                                                  m_Eigenvalues;
    MatrixType                                                  m_Eigenvectors;
    FixedArray< float, itkGetStaticConstMacro(ImageDimension) > m_AxesLength;
    RealType                                                    m_Eccentricity;
    RealType                                                    m_Elongation;
    RealType                                                    m_Orientation;
    BoundingBoxType                                             m_BoundingBox;
    LabelSizeType                                               m_BoundingBoxSize;
    RealType                                                    m_BoundingBoxVolume;
    LabelIndicesType                                            m_PixelIndices;
    BoundingBoxVerticesType                                     m_OrientedBoundingBoxVertices;
    RealType                                                    m_OrientedBoundingBoxVolume;
    LabelPointType                                              m_OrientedBoundingBoxSize;
    typename LabelImageType::Pointer m_OrientedLabelImage;
    typename IntensityImageType::Pointer m_OrientedIntensityImage;
    MatrixType     m_RotationMatrix;
    LabelPointType m_OrientedBoundingBoxOrigin;
  };

  /** Type of the map used to store data per label */
  // Map from the label to the class storing all of the geometry information.
  typedef itksys::hash_map< LabelPixelType, LabelGeometry >                          MapType;
  typedef typename itksys::hash_map< LabelPixelType, LabelGeometry >::iterator       MapIterator;
  typedef typename itksys::hash_map< LabelPixelType, LabelGeometry >::const_iterator MapConstIterator;

  // Macros for enabling the calculation of additional features.
  itkGetMacro(CalculatePixelIndices, bool);
  itkBooleanMacro(CalculatePixelIndices);
  void SetCalculatePixelIndices(const bool value)
  {
    // CalculateOrientedBoundingBox, CalculateOrientedLabelImage, and
    // CalculateOrientedIntensityImage all need CalculatePixelIndices to be
    // turned
    // on if they are turned on.  So, CalculatePixelIndices cannot be
    // turned off if any of these flags are turned on.
    if ( value == false )
      {
      if ( ( this->m_CalculateOrientedBoundingBox == true )
           || ( this->m_CalculateOrientedLabelRegions == true )
           || ( this->m_CalculateOrientedIntensityRegions == true ) )
        {
        // We cannot change the value, so return.
        return;
        }
      }

    if ( this->m_CalculatePixelIndices != value )
      {
      this->m_CalculatePixelIndices = value;
      this->Modified();
      }
  }

  itkGetMacro(CalculateOrientedBoundingBox, bool);
  itkBooleanMacro(CalculateOrientedBoundingBox);
  void SetCalculateOrientedBoundingBox(const bool value)
  {
    if ( this->m_CalculateOrientedBoundingBox != value )
      {
      this->m_CalculateOrientedBoundingBox = value;
      this->Modified();
      }

    // CalculateOrientedBoundingBox needs
    // CalculatePixelIndices to be turned on.
    if ( value == true )
      {
      this->SetCalculatePixelIndices(true);
      }
  }

  itkGetMacro(CalculateOrientedLabelRegions, bool);
  itkBooleanMacro(CalculateOrientedLabelRegions);
  void SetCalculateOrientedLabelRegions(const bool value)
  {
    if ( this->m_CalculateOrientedLabelRegions != value )
      {
      this->m_CalculateOrientedLabelRegions = value;
      this->Modified();

      // CalculateOrientedLabelImage needs
      // CalculateOrientedBoundingBox to be turned on.
      if ( value == true )
        {
        SetCalculateOrientedBoundingBox(true);
        }
      }
  }

  itkGetMacro(CalculateOrientedIntensityRegions, bool);
  itkBooleanMacro(CalculateOrientedIntensityRegions);
  void SetCalculateOrientedIntensityRegions(const bool value)
  {
    if ( this->m_CalculateOrientedIntensityRegions != value )
      {
      this->m_CalculateOrientedIntensityRegions = value;
      this->Modified();

      // CalculateOrientedIntensityImage needs
      // CalculateOrientedBoundingBox to be turned on.
      if ( value == true )
        {
        this->SetCalculateOrientedBoundingBox(true);
        }
      }
  }

  /** Set the intensity image */
  void SetIntensityInput(const TIntensityImage *input)
  {
    // Process object is not const-correct so the const casting is required.
    this->SetNthInput( 1, const_cast< TIntensityImage * >( input ) );
  }

  /** Get the label image */
  const TIntensityImage * GetIntensityInput() const
  {
    return static_cast< TIntensityImage * >( const_cast< DataObject * >( this->ProcessObject::GetInput(1) ) );
  }

  /** Does the specified label exist? Can only be called after
   * a call to Update(). */
  bool HasLabel(LabelPixelType label) const
  {
    return m_LabelGeometryMapper.find(label) != m_LabelGeometryMapper.end();
  }

  /** Get the number of labels used */
  SizeValueType GetNumberOfObjects() const
  {
    return m_LabelGeometryMapper.size();
  }

  SizeValueType GetNumberOfLabels() const
  {
    return this->GetNumberOfObjects();
  }

  /** Get the labels that are in the image. */
  std::vector< LabelPixelType > GetLabels() const
  {
    return m_AllLabels;
  }

  /** Return the all pixel indices for a label. */
  LabelIndicesType GetPixelIndices(LabelPixelType label) const;

  /** Return the number of pixels for a label.  This is the same as
   * the volume and the zero order moment */
  SizeValueType GetVolume(LabelPixelType label) const;

  /** Return the number of pixels for all labels. */
  //std::vector< SizeValueType > GetAllCounts() const;

  /** Return the computed integrated pixel intensity for a label. */
  RealType GetIntegratedIntensity(LabelPixelType label) const;

  /** Return the unweighted centroid for a label. */
  LabelPointType GetCentroid(LabelPixelType label) const;

  /** Return the weighted centroid for a label. */
  LabelPointType GetWeightedCentroid(LabelPixelType label) const;

  /** Return the eigenvalues as a vector. */
  VectorType GetEigenvalues(LabelPixelType label) const;

  /** Return the eigenvectors as a matrix. */
  MatrixType GetEigenvectors(LabelPixelType label) const;

  /** Return the axes length for a label. */
  AxesLengthType GetAxesLength(LabelPixelType label) const;

  /** Return the minor axis length for a label.  This is a convenience
   * class that returns the shortest length from GetAxesLength. */
  RealType GetMinorAxisLength(LabelPixelType label) const;

  /** Return the major axis length for a label.  This is a convenience
   * class that returns the longest length from GetAxesLength. */
  RealType GetMajorAxisLength(LabelPixelType label) const;

  /** Return the eccentricity for a label. */
  RealType GetEccentricity(LabelPixelType label) const;

  /** Return the elongation for a label.  This is defined as the
   * length of the major axis divided by the length of the minor axis. */
  RealType GetElongation(LabelPixelType label) const;

  /** Return the orientation for a label defined in radians. */
  RealType GetOrientation(LabelPixelType label) const;

  /** Return the computed bounding box for a label.
   * This is organized in min/max pairs as [min(X), max(X), min(Y),
   * max(Y), min(Z), max(Z),...]  */
  BoundingBoxType GetBoundingBox(LabelPixelType label) const;

  /** Return the volume of the bounding box. */
  RealType GetBoundingBoxVolume(LabelPixelType label) const;

  /** Return the size of the bounding box. */
  LabelSizeType GetBoundingBoxSize(LabelPixelType label) const;

  /** Return the oriented bounding box vertices.  The order of the
   * vertices corresponds with binary counting, where min is zero and
   * max is one.  For example, in 2D, binary counting will give
   * [0,0],[0,1],[1,0],[1,1], which corresponds to
   * [minX,minY],[minX,maxY],[maxX,minY],[maxX,maxY]. Each
   * vertex is defined as an ND point.   */
  BoundingBoxVerticesType GetOrientedBoundingBoxVertices(LabelPixelType label) const;

  /** Return the volume of the oriented bounding box. */
  RealType GetOrientedBoundingBoxVolume(LabelPixelType label) const;

  /** Return the size of the oriented bounding box. */
  LabelPointType GetOrientedBoundingBoxSize(LabelPixelType label) const;

  /** Return the origin of the oriented bounding box. */
  LabelPointType GetOrientedBoundingBoxOrigin(LabelPixelType label) const;

  /** Return the rotation matrix defined by the
   * eigenvalues/eigenvectors. */
  MatrixType GetRotationMatrix(LabelPixelType label) const;

  /** Return the region defined by the bounding box. */
  RegionType GetRegion(LabelPixelType label) const;

  /** Return the label region defined by the oriented bounding box. */
  TLabelImage * GetOrientedLabelImage(LabelPixelType label) const;

  /** Return the intensity region defined by the oriented bounding
   * box. */
  TIntensityImage * GetOrientedIntensityImage(LabelPixelType label) const;

#ifdef ITK_USE_CONCEPT_CHECKING
  // Begin concept checking
  itkConceptMacro( InputHasNumericTraitsCheck,
                   ( Concept::HasNumericTraits< PixelType > ) );
  // End concept checking
#endif

protected:
  LabelGeometryImageFilter();
  ~LabelGeometryImageFilter(){}
  void PrintSelf(std::ostream & os, Indent indent) const ITK_OVERRIDE;

  void GenerateData() ITK_OVERRIDE;

private:
  LabelGeometryImageFilter(const Self &) ITK_DELETE_FUNCTION;
  void operator=(const Self &) ITK_DELETE_FUNCTION;

  bool CalculateOrientedBoundingBoxVertices(vnl_symmetric_eigensystem< double > eig, LabelGeometry & m_LabelGeometry);

  bool m_CalculatePixelIndices;
  bool m_CalculateOrientedBoundingBox;
  bool m_CalculateOrientedLabelRegions;
  bool m_CalculateOrientedIntensityRegions;

  MapType       m_LabelGeometryMapper;
  LabelGeometry m_LabelGeometry;
  LabelsType    m_AllLabels;

  SimpleFastMutexLock m_Mutex;
}; // end of class

template< typename TLabelImage, typename TIntensityImage >
typename LabelGeometryImageFilter< TLabelImage, TIntensityImage >::MatrixType CalculateRotationMatrix(
  vnl_symmetric_eigensystem< double > eig);

template< typename TLabelImage, typename TIntensityImage, typename TGenericImage >
bool CalculateOrientedImage(
  LabelGeometryImageFilter< TLabelImage, TIntensityImage >  *filter,
  vnl_symmetric_eigensystem< double > eig,
  typename LabelGeometryImageFilter< TLabelImage, TIntensityImage >::LabelGeometry & labelGeometry,
  bool useLabelImage = true);
} // end namespace itk

#ifndef ITK_MANUAL_INSTANTIATION
#include "itkLabelGeometryImageFilter.hxx"
#endif

#endif