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/*=========================================================================
*
* Copyright Insight Software Consortium
*
* Licensed under the Apache License, Version 2.0 (the "License");
* you may not use this file except in compliance with the License.
* You may obtain a copy of the License at
*
* http://www.apache.org/licenses/LICENSE-2.0.txt
*
* Unless required by applicable law or agreed to in writing, software
* distributed under the License is distributed on an "AS IS" BASIS,
* WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
* See the License for the specific language governing permissions and
* limitations under the License.
*
*=========================================================================*/
#include <iostream>
#include "itkBioGenome.h"
#include "itkMath.h"
int itkBioGenomeTest( int, char * [] )
{
itk::bio::Genome genome;
genome.InsertGene("Tubulin");
genome.InsertGene("Cyclin");
const double tolerance = 1e-16;
const double inLevel = 0.74;
genome.SetExpressionLevel("Cyclin",inLevel);
const double outLevel = genome.GetExpressionLevel("Cyclin");
if( itk::Math::abs( inLevel - outLevel ) / outLevel > tolerance )
{
std::cerr << "Error in SetExpressionLevel()/GetExpressionLevel()" << std::endl;
return EXIT_FAILURE;
}
genome.KnockOutGene("Cyclin");
if( itk::Math::abs( genome.GetExpressionLevel("Cyclin") ) > tolerance )
{
std::cerr << "Error in KnockOutGene()/GetExpressionLevel()" << std::endl;
return EXIT_FAILURE;
}
const double value = 3.0;
const double threshold = 2.0;
const double slant = 5.0;
const double sigmoid = itk::bio::Genome::Sigmoide( threshold, slant, value );
const double expectedSigmoid = std::atan(( value - threshold ) / slant ) / 3.1416 + 0.5001;
if( itk::Math::abs( sigmoid - expectedSigmoid ) / expectedSigmoid > tolerance )
{
std::cerr << "Error in Sigmoid()" << std::endl;
std::cerr << "Expected valued = " << expectedSigmoid << std::endl;
std::cerr << "Computed valued = " << sigmoid << std::endl;
std::cerr << "Difference = " << ( sigmoid - expectedSigmoid ) << std::endl;
std::cerr << "Tolerance = " << tolerance << std::endl;
return EXIT_FAILURE;
}
const double cyclinLevel = 3.45;
const double tubulinLevel = 2.79;
genome.SetExpressionLevel("Cyclin" ,cyclinLevel );
genome.SetExpressionLevel("Tubulin",tubulinLevel);
itk::bio::Genome genome2;
genome2.Copy( genome );
if( itk::Math::abs( genome.GetExpressionLevel("Tubulin") -
genome2.GetExpressionLevel("Tubulin") ) > tolerance )
{
std::cerr << "Error in Copy()" << std::endl;
return EXIT_FAILURE;
}
if( itk::Math::abs( genome.GetExpressionLevel("Cyclin") -
genome2.GetExpressionLevel("Cyclin") ) > tolerance )
{
std::cerr << "Error in Copy()" << std::endl;
return EXIT_FAILURE;
}
std::cout << "Test Passed !" << std::endl;
return EXIT_SUCCESS;
}
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