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/*=========================================================================
*
* Copyright NumFOCUS
*
* Licensed under the Apache License, Version 2.0 (the "License");
* you may not use this file except in compliance with the License.
* You may obtain a copy of the License at
*
* https://www.apache.org/licenses/LICENSE-2.0.txt
*
* Unless required by applicable law or agreed to in writing, software
* distributed under the License is distributed on an "AS IS" BASIS,
* WITHOUT WARRANTIES OR CONDITIONS OF ANY KIND, either express or implied.
* See the License for the specific language governing permissions and
* limitations under the License.
*
*=========================================================================*/
#ifndef itkLevelSetMotionRegistrationFunction_h
#define itkLevelSetMotionRegistrationFunction_h
#include "itkPDEDeformableRegistrationFunction.h"
#include "itkPoint.h"
#include "itkCovariantVector.h"
#include "itkLinearInterpolateImageFunction.h"
#include "itkSmoothingRecursiveGaussianImageFilter.h"
#include <mutex>
namespace itk
{
/**
* \class LevelSetMotionRegistrationFunction
*
* This class encapsulate the PDE which drives the demons registration
* algorithm. It is used by LevelSetMotionRegistrationFilter to compute the
* output deformation field which will map a moving image onto a
* a fixed image.
*
* Non-integer moving image values are obtained by using
* interpolation. The default interpolator is of type
* LinearInterpolateImageFunction. The user may set other
* interpolators via method SetMovingImageInterpolator. Note that the input
* interpolator must derive from baseclass InterpolateImageFunction.
*
* This class is templated over the fixed image type, moving image type,
* and the deformation field type.
*
* \warning This filter assumes that the fixed image type, moving image type
* and deformation field type all have the same number of dimensions.
*
* \sa LevelSetMotionRegistrationFilter
* \ingroup FiniteDifferenceFunctions
* \ingroup ITKPDEDeformableRegistration
*/
template <typename TFixedImage, typename TMovingImage, typename TDisplacementField>
class ITK_TEMPLATE_EXPORT LevelSetMotionRegistrationFunction
: public PDEDeformableRegistrationFunction<TFixedImage, TMovingImage, TDisplacementField>
{
public:
ITK_DISALLOW_COPY_AND_MOVE(LevelSetMotionRegistrationFunction);
/** Standard class type aliases. */
using Self = LevelSetMotionRegistrationFunction;
using Superclass = PDEDeformableRegistrationFunction<TFixedImage, TMovingImage, TDisplacementField>;
using Pointer = SmartPointer<Self>;
using ConstPointer = SmartPointer<const Self>;
/** Method for creation through the object factory. */
itkNewMacro(Self);
/** \see LightObject::GetNameOfClass() */
itkOverrideGetNameOfClassMacro(LevelSetMotionRegistrationFunction);
/** MovingImage image type. */
using typename Superclass::MovingImageType;
using typename Superclass::MovingImagePointer;
using MovingSpacingType = typename MovingImageType::SpacingType;
/** FixedImage image type. */
using typename Superclass::FixedImageType;
using typename Superclass::FixedImagePointer;
using IndexType = typename FixedImageType::IndexType;
using SizeType = typename FixedImageType::SizeType;
using SpacingType = typename FixedImageType::SpacingType;
/** Deformation field type. */
using typename Superclass::DisplacementFieldType;
using typename Superclass::DisplacementFieldTypePointer;
/** Inherit some enums from the superclass. */
static constexpr unsigned int ImageDimension = Superclass::ImageDimension;
/** Inherit some enums from the superclass. */
using typename Superclass::PixelType;
using typename Superclass::RadiusType;
using typename Superclass::NeighborhoodType;
using typename Superclass::FloatOffsetType;
using typename Superclass::TimeStepType;
/** Interpolator type. */
using CoordinateType = double;
using CoordRepType = CoordinateType;
using InterpolatorType = InterpolateImageFunction<MovingImageType, CoordRepType>;
using InterpolatorPointer = typename InterpolatorType::Pointer;
using PointType = typename InterpolatorType::PointType;
using DefaultInterpolatorType = LinearInterpolateImageFunction<MovingImageType, CoordRepType>;
/** Vector types. */
using VectorType = Vector<double, Self::ImageDimension>;
using CovariantVectorType = CovariantVector<double, Self::ImageDimension>;
/** Moving image gradient calculator type. */
using MovingImageSmoothingFilterType = SmoothingRecursiveGaussianImageFilter<MovingImageType>;
using MovingImageSmoothingFilterPointer = typename MovingImageSmoothingFilterType::Pointer;
/** Set the moving image interpolator. */
void
SetMovingImageInterpolator(InterpolatorType * ptr)
{
m_MovingImageInterpolator = ptr;
}
/** Get the moving image interpolator. */
InterpolatorType *
GetMovingImageInterpolator()
{
return m_MovingImageInterpolator;
}
/** Compute the time global step that for this iteration.
*
* In this context, the timestep is a function of the maximum gradients.
*/
TimeStepType
ComputeGlobalTimeStep(void * GlobalData) const override;
/** Return a pointer to a global data structure that is passed to
* this object from the solver at each calculation. */
void *
GetGlobalDataPointer() const override
{
auto * global = new GlobalDataStruct();
global->m_SumOfSquaredDifference = 0.0;
global->m_NumberOfPixelsProcessed = 0L;
global->m_SumOfSquaredChange = 0;
global->m_MaxL1Norm = NumericTraits<double>::NonpositiveMin();
return global;
}
/** Release memory for global data structure.
*
* Updates the metric and releases the per-thread-global data.
*/
void
ReleaseGlobalDataPointer(void * gd) const override;
/** Set the object's state before each iteration. */
void
InitializeIteration() override;
/** Compute update at the specified neighbourhood.
*
* Called by a finite difference solver image filter at each pixel that does not lie on a data set boundary.
*/
PixelType
ComputeUpdate(const NeighborhoodType & it, void * gd, const FloatOffsetType & offset = FloatOffsetType(0.0)) override;
/** Get the metric value. The metric value is the mean square difference
* in intensity between the fixed image and transforming moving image
* computed over the overlapping region between the two images. */
virtual double
GetMetric() const
{
return m_Metric;
}
/** Get the rms change in deformation field. */
virtual double
GetRMSChange() const
{
return m_RMSChange;
}
/** Set/Get the parameter alpha. Alpha is added to the calculated
* gradient magnitude prior to normalizing the gradient to protect
* against numerical instability as the gradient magnitude
* approaches zero. This should be set as a small fraction of the
* intensity dynamic range, for instance 0.04%. Default is the
* absolute (not percentage) value of 0.1. */
virtual void
SetAlpha(double);
virtual double
GetAlpha() const;
/** Set/Get the threshold below which the absolute difference of
* intensity yields a match. When the intensities match between a
* moving and fixed image pixel, the update vector (for that
* iteration) will be the zero vector. Default is 0.001. */
virtual void
SetIntensityDifferenceThreshold(double);
virtual double
GetIntensityDifferenceThreshold() const;
/** Set/Get the threshold below which the gradient magnitude is
* considered the zero vector. Default is 1e-9. */
virtual void
SetGradientMagnitudeThreshold(double);
virtual double
GetGradientMagnitudeThreshold() const;
/** Set/Get the standard deviation used for smoothing the moving
* image prior to calculating gradients. */
virtual void
SetGradientSmoothingStandardDeviations(double);
virtual double
GetGradientSmoothingStandardDeviations() const;
/** Use the image spacing information in calculations. Use this option if you
* want derivatives in physical space. Default is UseImageSpacing ON, due to a
* backward compatibility state. */
void
SetUseImageSpacing(bool);
bool
GetUseImageSpacing() const;
protected:
LevelSetMotionRegistrationFunction();
~LevelSetMotionRegistrationFunction() override = default;
void
PrintSelf(std::ostream & os, Indent indent) const override;
/** FixedImage image neighborhood iterator type. */
using FixedImageNeighborhoodIteratorType = ConstNeighborhoodIterator<FixedImageType>;
/** A global data type for this class of equation. Used to store
* information for computing the metric. */
struct GlobalDataStruct
{
double m_SumOfSquaredDifference;
SizeValueType m_NumberOfPixelsProcessed;
double m_SumOfSquaredChange;
double m_MaxL1Norm;
};
private:
/** Cache fixed image information. */
SpacingType m_FixedImageSpacing{};
PointType m_FixedImageOrigin{};
/** Function to compute derivatives of the moving image. */
MovingImageSmoothingFilterPointer m_MovingImageSmoothingFilter{};
/** Function to interpolate the moving image. */
InterpolatorPointer m_MovingImageInterpolator{};
InterpolatorPointer m_SmoothMovingImageInterpolator{};
/** Stabilization factor for normalizing gradients to protect
* against small gradient magnitudes */
double m_Alpha{};
/** Threshold below which the gradient is considered zero. */
double m_GradientMagnitudeThreshold{};
/** Threshold below which two intensity value are assumed to match. */
double m_IntensityDifferenceThreshold{};
/** Smoothing parameter for gradient calculation */
double m_GradientSmoothingStandardDeviations{};
/** The metric value is the mean square difference in intensity between
* the fixed image and transforming moving image computed over the
* the overlapping region between the two images. */
mutable double m_Metric{};
mutable double m_SumOfSquaredDifference{};
mutable SizeValueType m_NumberOfPixelsProcessed{};
mutable double m_RMSChange{};
mutable double m_SumOfSquaredChange{};
/** Mutex lock to protect modification to metric. */
mutable std::mutex m_MetricCalculationMutex{};
bool m_UseImageSpacing{ true };
};
} // end namespace itk
#ifndef ITK_MANUAL_INSTANTIATION
# include "itkLevelSetMotionRegistrationFunction.hxx"
#endif
#endif
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