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package Bio::Coordinate::Collection;
our $AUTHORITY = 'cpan:BIOPERLML';
$Bio::Coordinate::Collection::VERSION = '1.007001';
use utf8;
use strict;
use warnings;
use Bio::Coordinate::Result;
use Bio::Coordinate::Result::Gap;
use parent qw(Bio::Root::Root Bio::Coordinate::MapperI);
# ABSTRACT: Noncontinuous match between two coordinate sets.
# AUTHOR: Heikki Lehvaslaiho <heikki@bioperl.org>
# OWNER: Heikki Lehvaslaiho
# LICENSE: Perl_5
# CONTRIBUTOR: Ewan Birney <birney@ebi.ac.uk>
sub new {
my($class,@args) = @_;
my $self = $class->SUPER::new(@args);
$self->{'_mappers'} = [];
my($in, $out, $strict, $mappers, $return_match) =
$self->_rearrange([qw(IN
OUT
STRICT
MAPPERS
RETURN_MATCH
)],
@args);
$in && $self->in($in);
$out && $self->out($out);
$mappers && $self->mappers($mappers);
$return_match && $self->return_match('return_match');
return $self; # success - we hope!
}
sub add_mapper {
my ($self,$value) = @_;
$self->throw("Is not a Bio::Coordinate::MapperI but a [$self]")
unless defined $value && $value->isa('Bio::Coordinate::MapperI');
# test pair range lengths
$self->warn("Coordinates in pair [". $value . ":" .
$value->in->seq_id . "/". $value->out->seq_id .
"] are not right.")
unless $value->test;
$self->_is_sorted(0);
push(@{$self->{'_mappers'}},$value);
}
sub mappers{
my ($self,@args) = @_;
if (@args) {
if (@args == 1 && ref $args[0] eq 'ARRAY') {
@args = @{$args[0]};
}
$self->throw("Is not a Bio::Coordinate::MapperI but a [$self]")
unless defined $args[0] && $args[0]->isa('Bio::Coordinate::MapperI');
push(@{$self->{'_mappers'}}, @args);
}
return @{$self->{'_mappers'}};
}
sub each_mapper{
my ($self) = @_;
return @{$self->{'_mappers'}};
}
sub mapper_count{
my $self = shift;
return scalar @{$self->{'_mappers'} || []};
}
sub swap {
my ($self) = @_;
$self->sort unless $self->_is_sorted;
map {$_->swap;} @{$self->{'_mappers'}};
($self->{'_in_ids'}, $self->{'_out_ids'}) =
($self->{'_out_ids'}, $self->{'_in_ids'});
1;
}
sub test {
my ($self) = @_;
my $res = 1;
foreach my $mapper ($self->each_mapper) {
unless( $mapper->test ) {
$self->warn("Coordinates in pair [". $mapper . ":" .
$mapper->in->seq_id . "/". $mapper->out->seq_id .
"] are not right.");
$res = 0;
}
}
$res;
}
sub map {
my ($self,$value) = @_;
$self->throw("Need to pass me a value.")
unless defined $value;
$self->throw("I need a Bio::Location, not [$value]")
unless $value->isa('Bio::LocationI');
$self->throw("No coordinate mappers!")
unless $self->each_mapper;
$self->sort unless $self->_is_sorted;
if ($value->isa("Bio::Location::SplitLocationI")) {
my $result = Bio::Coordinate::Result->new();
foreach my $loc ( $value->sub_Location(1) ) {
my $res = $self->_map($loc);
map { $result->add_sub_Location($_) } $res->each_Location;
}
return $result;
} else {
return $self->_map($value);
}
}
sub _map {
my ($self,$value) = @_;
my $result = Bio::Coordinate::Result->new(-is_remote=>1);
IDMATCH: {
# bail out now we if are forcing the use of an ID
# and it is not in this collection
last IDMATCH if defined $value->seq_id &&
! $self->{'_in_ids'}->{$value->seq_id};
foreach my $pair ($self->each_mapper) {
# if we are limiting input to a certain ID
next if defined $value->seq_id && $value->seq_id ne $pair->in->seq_id;
# if we haven't even reached the start, move on
next if $pair->in->end < $value->start;
# if we have over run, break
last if $pair->in->start > $value->end;
my $subres = $pair->map($value);
$result->add_result($subres);
}
}
$result->seq_id($result->match->seq_id) if $result->match;
unless ($result->each_Location) {
#build one gap;
my $gap = Bio::Location::Simple->new(-start => $value->start,
-end => $value->end,
-strand => $value->strand,
-location_type => $value->location_type
);
$gap->seq_id($value->seq_id) if defined $value->seq_id;
bless $gap, 'Bio::Coordinate::Result::Gap';
$result->seq_id($value->seq_id) if defined $value->seq_id;
$result->add_sub_Location($gap);
}
return $result;
}
sub sort{
my ($self) = @_;
@{$self->{'_mappers'}} = map { $_->[0] }
sort { $a->[1] <=> $b->[1] }
map { [ $_, $_->in->start] }
@{$self->{'_mappers'}};
#create hashes for sequence ids
$self->{'_in_ids'} = ();
$self->{'_out_ids'} = ();
foreach ($self->each_mapper) {
$self->{'_in_ids'}->{$_->in->seq_id} = 1;
$self->{'_out_ids'}->{$_->out->seq_id} = 1;
}
$self->_is_sorted(1);
}
sub _is_sorted{
my ($self,$value) = @_;
$self->{'_is_sorted'} = 1 if defined $value && $value;
return $self->{'_is_sorted'};
}
1;
__END__
=pod
=encoding utf-8
=head1 NAME
Bio::Coordinate::Collection - Noncontinuous match between two coordinate sets.
=head1 VERSION
version 1.007001
=head1 SYNOPSIS
# create Bio::Coordinate::Pairs or other Bio::Coordinate::MapperIs somehow
$pair1; $pair2;
# add them into a Collection
$collection = Bio::Coordinate::Collection->new;
$collection->add_mapper($pair1);
$collection->add_mapper($pair2);
# create a position and map it
$pos = Bio::Location::Simple->new (-start => 5, -end => 9 );
$res = $collection->map($pos);
$res->match->start == 1;
$res->match->end == 5;
# if mapping is many to one (*>1) or many-to-many (*>*)
# you have to give seq_id not get unrelevant entries
$pos = Bio::Location::Simple->new
(-start => 5, -end => 9 -seq_id=>'clone1');
=head1 DESCRIPTION
Generic, context neutral mapper to provide coordinate transforms
between two B<disjoint> coordinate systems. It brings into Bioperl the
functionality from Ewan Birney's Bio::EnsEMBL::Mapper ported into
current bioperl.
This class is aimed for representing mapping between whole chromosomes
and contigs, or between contigs and clones, or between sequencing
reads and assembly. The submaps are automatically sorted, so they can
be added in any order.
To map coordinates to the other direction, you have to swap() the
collection. Keeping track of the direction and ID restrictions
are left to the calling code.
=head1 ATTRIBUTES
=head2 mappers
Title : mappers
Usage : $obj->mappers();
Function: Returns or sets a list of mappers.
Example :
Returns : array of mappers
Args : array of mappers
=head2 each_mapper
Title : each_mapper
Usage : $obj->each_mapper();
Function: Returns a list of mappers.
Example :
Returns : list of mappers
Args : none
=head2 mapper_count
Title : mapper_count
Usage : my $count = $collection->mapper_count;
Function: Get the count of the number of mappers stored
in this collection
Example :
Returns : integer
Args : none
=head1 METHODS
=head2 new
=head2 add_mapper
Title : add_mapper
Usage : $obj->add_mapper($mapper)
Function: Pushes one Bio::Coordinate::MapperI into the list of mappers.
Sets _is_sorted() to false.
Example :
Returns : 1 when succeeds, 0 for failure.
Args : mapper object
=head2 swap
Title : swap
Usage : $obj->swap;
Function: Swap the direction of mapping;input <-> output
Example :
Returns : 1
Args :
=head2 test
Title : test
Usage : $obj->test;
Function: test that both components of all pairs are of the same length.
Ran automatically.
Example :
Returns : boolean
Args :
=head2 map
Title : map
Usage : $newpos = $obj->map($pos);
Function: Map the location from the input coordinate system
to a new value in the output coordinate system.
Example :
Returns : new value in the output coordinate system
Args : integer
=head2 sort
Title : sort
Usage : $obj->sort;
Function: Sort function so that all mappings are sorted by
input coordinate start
Example :
Returns : 1
Args :
=head1 INTERNAL METHODS
=head2 _map
Title : _map
Usage : $newpos = $obj->_map($simpleloc);
Function: Internal method that does the actual mapping. Called multiple times
by map() if the location to be mapped is a split location
Example :
Returns : new location in the output coordinate system or undef
Args : Bio::Location::Simple
=head2 _is_sorted
Title : _is_sorted
Usage : $newpos = $obj->_is_sorted;
Function: toggle for whether the (internal) coordinate mapper data are sorted
Example :
Returns : boolean
Args : boolean
=head1 FEEDBACK
=head2 Mailing lists
User feedback is an integral part of the evolution of this and other
Bioperl modules. Send your comments and suggestions preferably to
the Bioperl mailing list. Your participation is much appreciated.
bioperl-l@bioperl.org - General discussion
http://bioperl.org/wiki/Mailing_lists - About the mailing lists
=head2 Support
Please direct usage questions or support issues to the mailing list:
I<bioperl-l@bioperl.org>
rather than to the module maintainer directly. Many experienced and
reponsive experts will be able look at the problem and quickly
address it. Please include a thorough description of the problem
with code and data examples if at all possible.
=head2 Reporting bugs
Report bugs to the Bioperl bug tracking system to help us keep track
of the bugs and their resolution. Bug reports can be submitted via the
web:
https://github.com/bioperl/%%7Bdist%7D
=head1 AUTHOR
Heikki Lehvaslaiho <heikki@bioperl.org>
=head1 COPYRIGHT
This software is copyright (c) by Heikki Lehvaslaiho.
This software is available under the same terms as the perl 5 programming language system itself.
=cut
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