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/*
* Copyright (C) 2011 Regents of the University of Michigan
*
* This program is free software: you can redistribute it and/or modify
* it under the terms of the GNU General Public License as published by
* the Free Software Foundation, either version 3 of the License, or
* (at your option) any later version.
*
* This program is distributed in the hope that it will be useful,
* but WITHOUT ANY WARRANTY; without even the implied warranty of
* MERCHANTABILITY or FITNESS FOR A PARTICULAR PURPOSE. See the
* GNU General Public License for more details.
*
* You should have received a copy of the GNU General Public License
* along with this program. If not, see <http://www.gnu.org/licenses/>.
*/
//////////////////////////////////////////////////////////////////////////
#include "NonOverlapRegions.h"
#include <iostream>
NonOverlapRegions::NonOverlapRegions()
: myRegions()
{
}
NonOverlapRegions::~NonOverlapRegions()
{
myRegions.clear();
}
void NonOverlapRegions::add(const char* chrom, int32_t start, int32_t end)
{
// Add the region.
myRegions[chrom].add(start, end);
}
bool NonOverlapRegions::inRegion(const char* chrom, int32_t pos)
{
// Return whether or not the position was found within a region.
// Note, this will create a NonOverlapRegion for this chrom if it
// did not already exist, but it won't have any regions.
return(myRegions[chrom].inRegion(pos));
}
NonOverlapRegionPos::NonOverlapRegionPos()
: myRegions()
{
myRegionIter = myRegions.begin();
myTmpIter = myRegions.begin();
}
NonOverlapRegionPos::NonOverlapRegionPos(const NonOverlapRegionPos& reg)
: myRegions()
{
myRegionIter = myRegions.begin();
myTmpIter = myRegions.begin();
}
NonOverlapRegionPos::~NonOverlapRegionPos()
{
myRegionIter = myRegions.begin();
myTmpIter = myRegions.begin();
myRegions.clear();
}
void NonOverlapRegionPos::add(int32_t start, int32_t end)
{
// Check to see if the start/end are valid in relation.
if(start >= end)
{
std::cerr << "NonOverlapRegionPos::add: Invalid Range, "
<< "start must be < end, but " << start << " >= " << end
<< std::endl;
return;
}
bool added = false;
// Locate the correct position in the region list for this start/end.
if(inRegion(start))
{
// Check if the region end needs to be updated.
if(end > myRegionIter->second)
{
myRegionIter->second = end;
}
added = true;
}
else
{
// Check to see if we are at the end.
if(myRegionIter != myRegions.end())
{
// Not at the end.
// Check to see if the region overlaps the current region.
if(end >= myRegionIter->first)
{
// Overlaps, so update the start.
myRegionIter->first = start;
// Check if the end needs to be updated.
if(myRegionIter->second < end)
{
myRegionIter->second = end;
}
added = true;
}
}
}
// If we already added the record, check to see if the end of the
// new region overlaps any additional regions (know that myRegionIter is
// not at the end.
if(added)
{
// Check to see if any other regions were overlapped by this record.
myTmpIter = myRegionIter;
++myTmpIter;
while(myTmpIter != myRegions.end())
{
// If the region starts before the end of this one, consume it.
if(myTmpIter->first <= end)
{
if(myTmpIter->second > myRegionIter->second)
{
// Update this region with the new end.
myRegionIter->second = myTmpIter->second;
}
myTmpIter = myRegions.erase(myTmpIter);
}
else
{
// This region is not overlapped by the new region, so stop.
break;
}
}
}
else
{
// Add the region.
myRegionIter = myRegions.insert(myRegionIter,
std::make_pair(start, end));
}
}
bool NonOverlapRegionPos::inRegion(int32_t pos)
{
// Return whether or not the position was found within a region.
// If it is found within the region, myRegionIter will point to the region
// otherwise myRegionIter will point to the region after the position
// or to the end if the position is after the last region.
// Determine if it needs to search to the left
// a) it is at the end
// b) the region starts after the position.
if(myRegionIter == myRegions.end())
{
// If the iterator is at the end, search to the left.
return(findLeft(pos));
}
else if(pos < myRegionIter->first)
{
// Not at the end, so search left if the position is less
// than this region's start.
return(findLeft(pos));
}
else
{
return(findRight(pos));
}
}
bool NonOverlapRegionPos::findRight(int32_t pos)
{
// Keep looping until the end or until the position is found.
while(myRegionIter != myRegions.end())
{
// Check to see if we have passed the position.
if(pos < myRegionIter->first)
{
// stop here, position comes before this region,
// so myRegionIter is pointing to just after it,
// but was not found in the region.
return(false);
}
else if(pos < myRegionIter->second)
{
// the position is in the region, so return true.
return(true);
}
else
{
// The position is after this region, so increment.
++myRegionIter;
}
}
// exited because we are at the end of the regions and the position was
// not found.
return(false);
}
bool NonOverlapRegionPos::findLeft(int32_t pos)
{
if(myRegionIter == myRegions.end())
{
if(myRegionIter == myRegions.begin())
{
// There is nothing in this list, so just return.
return(false);
}
// Move 1 lower than the end.
--myRegionIter;
}
while(myRegionIter->first > pos)
{
// This region is before our position, so move to the previous region
// unless this is the first region in the list.
if(myRegionIter == myRegions.begin())
{
// Did not find the position and the iter is at the element
// just after the position.
return(false);
}
// Not yet to the beginning of the list, so decrement.
--myRegionIter;
}
// At this point, the regions iter points to a region that starts
// before the position.
// Determine if the position is in the region by checking if it is
// less than the end of the region.
if(pos < myRegionIter->second)
{
// in the region.
return(true);
}
// This region ends before this position. The iterator needs to point
// to the region after the position, so increment it.
++myRegionIter;
return(false);
}
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