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/*
* The MIT License
*
* Wavefront Alignment Algorithms
* Copyright (c) 2017 by Santiago Marco-Sola <santiagomsola@gmail.com>
*
* This file is part of Wavefront Alignment Algorithms.
*
* Permission is hereby granted, free of charge, to any person obtaining a copy
* of this software and associated documentation files (the "Software"), to deal
* in the Software without restriction, including without limitation the rights
* to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
* copies of the Software, and to permit persons to whom the Software is
* furnished to do so, subject to the following conditions:
*
* The above copyright notice and this permission notice shall be included in all
* copies or substantial portions of the Software.
*
* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
* IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
* FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
* AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
* LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
* OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
* SOFTWARE.
*
* PROJECT: Wavefront Alignment Algorithms
* AUTHOR(S): Santiago Marco-Sola <santiagomsola@gmail.com>
* DESCRIPTION: C++ bindings for the WaveFront Alignment modules
*/
#ifndef BINDINGS_CPP_WFALIGNER_HPP_
#define BINDINGS_CPP_WFALIGNER_HPP_
#include <string>
#include "../../wavefront/wfa.hpp"
/*
* Namespace
*/
namespace wfa {
/*
* General Wavefront Aligner
*/
class WFAligner {
public:
// Configuration
enum MemoryModel {
MemoryHigh,
MemoryMed,
MemoryLow,
MemoryUltralow,
};
enum AlignmentScope {
Score,
Alignment,
};
enum AlignmentStatus {
StatusSuccessful = WF_STATUS_SUCCESSFUL,
StatusUnfeasible = WF_STATUS_UNFEASIBLE,
StatusMaxScoreReached = WF_STATUS_MAX_SCORE_REACHED,
StatusOOM = WF_STATUS_OOM,
};
// Align End-to-end
AlignmentStatus alignEnd2EndLambda(
const int patternLength,
const int textLength);
AlignmentStatus alignEnd2End(
const char* const pattern,
const int patternLength,
const char* const text,
const int textLength);
AlignmentStatus alignEnd2End(
std::string& pattern,
std::string& text);
// Align Ends-free
AlignmentStatus alignEndsFreeLambda(
const int patternLength,
const int patternBeginFree,
const int patternEndFree,
const int textLength,
const int textBeginFree,
const int textEndFree);
AlignmentStatus alignEndsFree(
const char* const pattern,
const int patternLength,
const int patternBeginFree,
const int patternEndFree,
const char* const text,
const int textLength,
const int textBeginFree,
const int textEndFree);
AlignmentStatus alignEndsFree(
std::string& pattern,
const int patternBeginFree,
const int patternEndFree,
std::string& text,
const int textBeginFree,
const int textEndFree);
// Alignment resume
AlignmentStatus alignResume();
// Heuristics
void setHeuristicNone();
void setHeuristicBandedStatic(
const int band_min_k,
const int band_max_k);
void setHeuristicBandedAdaptive(
const int band_min_k,
const int band_max_k,
const int steps_between_cutoffs = 1);
void setHeuristicWFadaptive(
const int min_wavefront_length,
const int max_distance_threshold,
const int steps_between_cutoffs = 1);
void setHeuristicWFmash(
const int min_wavefront_length,
const int max_distance_threshold,
const int steps_between_cutoffs = 1);
void setHeuristicXDrop(
const int xdrop,
const int steps_between_cutoffs = 1);
void setHeuristicZDrop(
const int zdrop,
const int steps_between_cutoffs = 1);
// Custom extend-match function (lambda)
void setMatchFunct(
int (*matchFunct)(int,int,void*),
void* matchFunctArguments);
// Limits
void setMaxAlignmentScore(
const int maxAlignmentScore);
void setMaxMemory(
const uint64_t maxMemoryResident,
const uint64_t maxMemoryAbort);
// Parallelization
void setMaxNumThreads(
const int maxNumThreads);
void setMinOffsetsPerThread(
const int minOffsetsPerThread);
// Accessors
int getAlignmentScore();
int getAlignmentStatus();
void getAlignmentCigar(
char** const cigarOperations,
int* cigarLength);
std::string getAlignmentCigar();
// Misc
char* strError(
const int wfErrorCode);
void setVerbose(
const int verbose);
protected:
wavefront_aligner_attr_t attributes;
wavefront_aligner_t* wfAligner;
// Setup
WFAligner(
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
~WFAligner();
private:
WFAligner(const WFAligner&);
};
/*
* Indel Aligner (a.k.a Longest Common Subsequence - LCS)
*/
class WFAlignerIndel : public WFAligner {
public:
WFAlignerIndel(
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
};
/*
* Edit Aligner (a.k.a Levenshtein)
*/
class WFAlignerEdit : public WFAligner {
public:
WFAlignerEdit(
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
};
/*
* Gap-Linear Aligner (a.k.a Needleman-Wunsch)
*/
class WFAlignerGapLinear : public WFAligner {
public:
WFAlignerGapLinear(
const int mismatch,
const int indel,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
WFAlignerGapLinear(
const int match,
const int mismatch,
const int indel,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
};
/*
* Gap-Affine Aligner (a.k.a Smith-Waterman-Gotoh)
*/
class WFAlignerGapAffine : public WFAligner {
public:
WFAlignerGapAffine(
const int mismatch,
const int gapOpening,
const int gapExtension,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
WFAlignerGapAffine(
const int match,
const int mismatch,
const int gapOpening,
const int gapExtension,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
};
/*
* Gap-Affine Dual-Cost Aligner (a.k.a. concave 2-pieces)
*/
class WFAlignerGapAffine2Pieces : public WFAligner {
public:
WFAlignerGapAffine2Pieces(
const int mismatch,
const int gapOpening1,
const int gapExtension1,
const int gapOpening2,
const int gapExtension2,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
WFAlignerGapAffine2Pieces(
const int match,
const int mismatch,
const int gapOpening1,
const int gapExtension1,
const int gapOpening2,
const int gapExtension2,
const AlignmentScope alignmentScope,
const MemoryModel memoryModel = MemoryHigh);
};
} /* namespace wfa */
#endif /* BINDINGS_CPP_WFALIGNER_HPP_ */
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