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/*
* The MIT License
*
* Wavefront Alignment Algorithms
* Copyright (c) 2017 by Santiago Marco-Sola <santiagomsola@gmail.com>
*
* This file is part of Wavefront Alignment Algorithms.
*
* Permission is hereby granted, free of charge, to any person obtaining a copy
* of this software and associated documentation files (the "Software"), to deal
* in the Software without restriction, including without limitation the rights
* to use, copy, modify, merge, publish, distribute, sublicense, and/or sell
* copies of the Software, and to permit persons to whom the Software is
* furnished to do so, subject to the following conditions:
*
* The above copyright notice and this permission notice shall be included in all
* copies or substantial portions of the Software.
*
* THE SOFTWARE IS PROVIDED "AS IS", WITHOUT WARRANTY OF ANY KIND, EXPRESS OR
* IMPLIED, INCLUDING BUT NOT LIMITED TO THE WARRANTIES OF MERCHANTABILITY,
* FITNESS FOR A PARTICULAR PURPOSE AND NONINFRINGEMENT. IN NO EVENT SHALL THE
* AUTHORS OR COPYRIGHT HOLDERS BE LIABLE FOR ANY CLAIM, DAMAGES OR OTHER
* LIABILITY, WHETHER IN AN ACTION OF CONTRACT, TORT OR OTHERWISE, ARISING FROM,
* OUT OF OR IN CONNECTION WITH THE SOFTWARE OR THE USE OR OTHER DEALINGS IN THE
* SOFTWARE.
*
* PROJECT: Wavefront Alignment Algorithms
* AUTHOR(S): Santiago Marco-Sola <santiagomsola@gmail.com>
* DESCRIPTION: WaveFront alignment module for offloading partial backtraces
*/
#include "utils/commons.h"
#include "wfa.h"
#include "utils/string_padded.h"
#include "wavefront_backtrace_offload.h"
/*
* Backtrace-blocks offloading
*/
void wavefront_backtrace_offload_blocks_selective(
wf_offset_t* const out_offsets,
pcigar_t* const out_bt_pcigar,
bt_block_idx_t* const out_bt_prev,
const int lo,
const int hi,
const pcigar_t occupation_mask,
wf_backtrace_buffer_t* const bt_buffer) {
// Fetch BT-buffer free memory
int bt_blocks_available;
bt_block_t* bt_block_mem;
bt_block_idx_t global_pos = wf_backtrace_buffer_get_mem(bt_buffer,&bt_block_mem,&bt_blocks_available);
bt_block_idx_t current_pos = global_pos;
const int max_pos = current_pos + bt_blocks_available;
// Check PCIGAR buffers full and off-load if needed
int k;
for (k=lo;k<=hi;++k) {
if (out_offsets[k]>=0 && PCIGAR_IS_UTILISED(out_bt_pcigar[k],occupation_mask)) {
// Store
bt_block_mem->pcigar = out_bt_pcigar[k];
bt_block_mem->prev_idx = out_bt_prev[k];
bt_block_mem++;
// Reset
out_bt_pcigar[k] = 0;
out_bt_prev[k] = current_pos;
current_pos++;
// Update pos
if (current_pos >= max_pos) {
wf_backtrace_buffer_add_used(bt_buffer,current_pos-global_pos);
global_pos = wf_backtrace_buffer_get_mem(bt_buffer,&bt_block_mem,&bt_blocks_available);
}
}
}
wf_backtrace_buffer_add_used(bt_buffer,current_pos-global_pos);
}
/*
* Backtrace offloading (linear)
*/
int wavefront_backtrace_offload_blocks_linear(
wavefront_aligner_t* const wf_aligner,
wf_offset_t* const out_offsets,
pcigar_t* const out_bt_pcigar,
bt_block_idx_t* const out_bt_prev,
const int lo,
const int hi) {
// Parameters
const wavefront_memory_t wavefront_memory = wf_aligner->memory_mode;
wf_backtrace_buffer_t* const bt_buffer = wf_aligner->wf_components.bt_buffer;
// Select memory-mode
switch (wavefront_memory) {
case wavefront_memory_med:
wavefront_backtrace_offload_blocks_selective(
out_offsets,out_bt_pcigar,out_bt_prev,
lo,hi,PCIGAR_HALF_FULL_MASK,bt_buffer);
return PCIGAR_MAX_LENGTH/2; // Half occupancy
break;
case wavefront_memory_low:
wavefront_backtrace_offload_blocks_selective(
out_offsets,out_bt_pcigar,out_bt_prev,
lo,hi,PCIGAR_FULL_MASK,bt_buffer);
return PCIGAR_MAX_LENGTH-1; // At least 1-slots free
break;
default:
fprintf(stderr,"[WFA::compute] Wrong memory-mode\n");
exit(1);
}
}
void wavefront_backtrace_offload_linear(
wavefront_aligner_t* const wf_aligner,
const wavefront_set_t* const wavefront_set,
const int lo,
const int hi) {
// Paramters
wavefront_t* const wf_m = wavefront_set->out_mwavefront;
const wavefront_t* const m_misms = wavefront_set->in_mwavefront_misms;
const wavefront_t* const m_open1 = wavefront_set->in_mwavefront_open1;
// Compute BT occupancy maximum
int occ_max_m = 0, occ_max_indel = 0;
if (!m_open1->null) occ_max_indel = m_open1->bt_occupancy_max;
if (!m_misms->null) occ_max_m = m_misms->bt_occupancy_max;
const int occ_max = MAX(occ_max_indel,occ_max_m) + 1;
// Set new occupancy
wf_m->bt_occupancy_max = occ_max;
// Offload if necessary (Gap-Linear)
if (!wf_m->null && occ_max >= PCIGAR_MAX_LENGTH) {
wf_offset_t* const out_m = wavefront_set->out_mwavefront->offsets;
pcigar_t* const out_m_bt_pcigar = wavefront_set->out_mwavefront->bt_pcigar;
bt_block_idx_t* const out_m_bt_prev = wavefront_set->out_mwavefront->bt_prev;
wavefront_set->out_mwavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_linear(
wf_aligner,out_m,out_m_bt_pcigar,out_m_bt_prev,lo,hi);
}
}
/*
* Backtrace offloading (gap-affine)
*/
int wavefront_backtrace_offload_blocks_affine(
wavefront_aligner_t* const wf_aligner,
wf_offset_t* const out_offsets,
pcigar_t* const out_bt_pcigar,
bt_block_idx_t* const out_bt_prev,
const int lo,
const int hi) {
// Parameters
const wavefront_memory_t wavefront_memory = wf_aligner->memory_mode;
wf_backtrace_buffer_t* const bt_buffer = wf_aligner->wf_components.bt_buffer;
// Select memory-mode
switch (wavefront_memory) {
case wavefront_memory_med:
wavefront_backtrace_offload_blocks_selective(
out_offsets,out_bt_pcigar,out_bt_prev,
lo,hi,PCIGAR_HALF_FULL_MASK,bt_buffer);
return PCIGAR_MAX_LENGTH/2; // Half occupancy
case wavefront_memory_low:
wavefront_backtrace_offload_blocks_selective(
out_offsets,out_bt_pcigar,out_bt_prev,
lo,hi,PCIGAR_ALMOST_FULL_MASK,bt_buffer);
return PCIGAR_MAX_LENGTH-2; // At least 2-slots free
default:
fprintf(stderr,"[WFA::compute] Wrong memory-mode\n");
exit(1);
return 0;
}
}
void wavefront_backtrace_offload_occupation_affine(
wavefront_aligner_t* const wf_aligner,
const wavefront_set_t* const wavefront_set) {
// Parameters
const distance_metric_t distance_metric = wf_aligner->penalties.distance_metric;
// Select distance metric
int occ_max_m = 0;
int occ_max_i1 = 0, occ_max_i2 = 0;
int occ_max_d1 = 0, occ_max_d2 = 0;
if (distance_metric == gap_affine) {
// Parameters
const wavefront_t* const m_misms = wavefront_set->in_mwavefront_misms;
const wavefront_t* const m_open1 = wavefront_set->in_mwavefront_open1;
const wavefront_t* const i1_ext = wavefront_set->in_i1wavefront_ext;
const wavefront_t* const d1_ext = wavefront_set->in_d1wavefront_ext;
// Compute BT occupancy maximum
if (!m_open1->null) {
occ_max_i1 = m_open1->bt_occupancy_max + 1;
occ_max_d1 = m_open1->bt_occupancy_max + 1;
}
if (!i1_ext->null) occ_max_i1 = MAX(occ_max_i1,i1_ext->bt_occupancy_max+1);
if (!d1_ext->null) occ_max_d1 = MAX(occ_max_d1,d1_ext->bt_occupancy_max+1);
if (!m_misms->null) occ_max_m = m_misms->bt_occupancy_max;
if (occ_max_m < occ_max_i1) occ_max_m = occ_max_i1;
if (occ_max_m < occ_max_d1) occ_max_m = occ_max_d1;
++occ_max_m;
// Set new occupancy
wavefront_set->out_i1wavefront->bt_occupancy_max = occ_max_i1;
wavefront_set->out_d1wavefront->bt_occupancy_max = occ_max_d1;
wavefront_set->out_mwavefront->bt_occupancy_max = occ_max_m;
} else { // distance_metric == gap_affine_2p
// Parameters
const wavefront_t* const m_misms = wavefront_set->in_mwavefront_misms;
const wavefront_t* const m_open1 = wavefront_set->in_mwavefront_open1;
const wavefront_t* const m_open2 = wavefront_set->in_mwavefront_open2;
const wavefront_t* const i1_ext = wavefront_set->in_i1wavefront_ext;
const wavefront_t* const i2_ext = wavefront_set->in_i2wavefront_ext;
const wavefront_t* const d1_ext = wavefront_set->in_d1wavefront_ext;
const wavefront_t* const d2_ext = wavefront_set->in_d2wavefront_ext;
// Compute BT occupancy maximum (I)
if (!m_open1->null) {
occ_max_i1 = m_open1->bt_occupancy_max + 1;
occ_max_d1 = m_open1->bt_occupancy_max + 1;
}
// Compute BT occupancy maximum (D)
if (!i1_ext->null) occ_max_i1 = MAX(occ_max_i1,i1_ext->bt_occupancy_max+1);
if (!d1_ext->null) occ_max_d1 = MAX(occ_max_d1,d1_ext->bt_occupancy_max+1);
if (!m_open2->null) {
occ_max_i2 = m_open2->bt_occupancy_max + 1;
occ_max_d2 = m_open2->bt_occupancy_max + 1;
}
if (!i2_ext->null) occ_max_i2 = MAX(occ_max_i2,i2_ext->bt_occupancy_max+1);
if (!d2_ext->null) occ_max_d2 = MAX(occ_max_d2,d2_ext->bt_occupancy_max+1);
// Compute BT occupancy maximum (M)
if (!m_misms->null) occ_max_m = m_misms->bt_occupancy_max;
if (occ_max_m < occ_max_i1) occ_max_m = occ_max_i1;
if (occ_max_m < occ_max_i2) occ_max_m = occ_max_i2;
if (occ_max_m < occ_max_d1) occ_max_m = occ_max_d1;
if (occ_max_m < occ_max_d2) occ_max_m = occ_max_d2;
++occ_max_m;
// Set new occupancy
wavefront_set->out_i1wavefront->bt_occupancy_max = occ_max_i1;
wavefront_set->out_i2wavefront->bt_occupancy_max = occ_max_i2;
wavefront_set->out_d1wavefront->bt_occupancy_max = occ_max_d1;
wavefront_set->out_d2wavefront->bt_occupancy_max = occ_max_d2;
wavefront_set->out_mwavefront->bt_occupancy_max = occ_max_m;
}
}
void wavefront_backtrace_offload_affine(
wavefront_aligner_t* const wf_aligner,
const wavefront_set_t* const wavefront_set,
const int lo,
const int hi) {
// Parameters
const distance_metric_t distance_metric = wf_aligner->penalties.distance_metric;
// Compute maximum occupancy
wavefront_backtrace_offload_occupation_affine(wf_aligner,wavefront_set);
// Offload if necessary (Gap-Affine)
const wavefront_t* const wf_m = wavefront_set->out_mwavefront;
if (!wf_m->null && wf_m->bt_occupancy_max >= PCIGAR_MAX_LENGTH-1) {
wf_offset_t* const out_m = wavefront_set->out_mwavefront->offsets;
pcigar_t* const out_m_bt_pcigar = wavefront_set->out_mwavefront->bt_pcigar;
bt_block_idx_t* const out_m_bt_prev = wavefront_set->out_mwavefront->bt_prev;
wavefront_set->out_mwavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_affine(
wf_aligner,out_m,out_m_bt_pcigar,out_m_bt_prev,lo,hi);
}
const wavefront_t* const wf_i1 = wavefront_set->out_i1wavefront;
if (!wf_i1->null && wf_i1->bt_occupancy_max >= PCIGAR_MAX_LENGTH-1) {
wf_offset_t* const out_i1 = wavefront_set->out_i1wavefront->offsets;
pcigar_t* const out_i1_bt_pcigar = wavefront_set->out_i1wavefront->bt_pcigar;
bt_block_idx_t* const out_i1_bt_prev = wavefront_set->out_i1wavefront->bt_prev;
wavefront_set->out_i1wavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_affine(
wf_aligner,out_i1,out_i1_bt_pcigar,out_i1_bt_prev,lo,hi);
}
const wavefront_t* const wf_d1 = wavefront_set->out_d1wavefront;
if (!wf_d1->null && wf_d1->bt_occupancy_max >= PCIGAR_MAX_LENGTH-1) {
wf_offset_t* const out_d1 = wavefront_set->out_d1wavefront->offsets;
pcigar_t* const out_d1_bt_pcigar = wavefront_set->out_d1wavefront->bt_pcigar;
bt_block_idx_t* const out_d1_bt_prev = wavefront_set->out_d1wavefront->bt_prev;
wavefront_set->out_d1wavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_affine(
wf_aligner,out_d1,out_d1_bt_pcigar,out_d1_bt_prev,lo,hi);
}
if (distance_metric == gap_affine) return;
// Offload if necessary (Gap-Affine-2p)
const wavefront_t* const wf_i2 = wavefront_set->out_i2wavefront;
if (!wf_i2->null && wf_i2->bt_occupancy_max >= PCIGAR_MAX_LENGTH-1) {
wf_offset_t* const out_i2 = wavefront_set->out_i2wavefront->offsets;
pcigar_t* const out_i2_bt_pcigar = wavefront_set->out_i2wavefront->bt_pcigar;
bt_block_idx_t* const out_i2_bt_prev = wavefront_set->out_i2wavefront->bt_prev;
wavefront_set->out_i2wavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_affine(
wf_aligner,out_i2,out_i2_bt_pcigar,out_i2_bt_prev,lo,hi);
}
const wavefront_t* const wf_d2 = wavefront_set->out_d2wavefront;
if (!wf_d2->null && wf_d2->bt_occupancy_max >= PCIGAR_MAX_LENGTH-1) {
wf_offset_t* const out_d2 = wavefront_set->out_d2wavefront->offsets;
pcigar_t* const out_d2_bt_pcigar = wavefront_set->out_d2wavefront->bt_pcigar;
bt_block_idx_t* const out_d2_bt_prev = wavefront_set->out_d2wavefront->bt_prev;
wavefront_set->out_d2wavefront->bt_occupancy_max =
wavefront_backtrace_offload_blocks_affine(
wf_aligner,out_d2,out_d2_bt_pcigar,out_d2_bt_prev,lo,hi);
}
}
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