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|
> 1== M63632 1 Lampetra japonica rhodopsin <>[BBRC174,1125-1132'91]
M-----------------------------------------------------------
---NG------------TEGDNFYVPFSNKTGLAR-------------------------
----------------------------------SP---------------------YEY
--------------------PQY---------------------YLAEPW----------
-----------KYSALAAYMFFLILVGFPVNFLTLFVTVQHKKLRTPLNYILLNLAMANL
FMVLFG-FTVTMYTSMN-GYFV--FGPTMCSIEGFFATLGGEVALWSLVVLAIERYIVIC
KPMGNFRF-GNTHAIMGVAFTWIMALAC-AAPPLV-GWSR-------YIPEGMQCSCGPD
YYTLNPNFNNESYVVYMFVVHFLVPFVIIFFCYGRLLCTVKEAAAAQQESA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEKEVTRMVVLMVIGFLVCWVPYASVAFYIFT-HQG-SD-FG
ATFMTLPAFFAKSSALYNPVIYILMNKQFRNCMITTLCC---------------------
------------------------------------------------------------
-----------------------------------------GKN-PLGDDE-SGA----S
TSKTE------------------VSSVSTSPV-------------------------S--
--------------------------------------PA
> 2== U22180 1 rat opsin <rod>[J.Mol.Neurosci.5(3),207-209'94]
M-----------------------------------------------------------
---NG------------TEGPNFYVPFSNITGVVR-------------------------
----------------------------------SP---------------------FEQ
--------------------PQY---------------------YLAEPW----------
-----------QFSMLAAYMFLLIVLGFPINFLTLYVTVQHKKLRTPLNYILLNLAVADL
FMVFGG-FTTTLYTSLH-GYFV--FGPTGCNLEGFFATLGGEIGLWSLVVLAIERYVVVC
KPMSNFRF-GENHAIMGVAFTWVMALAC-AAPPLV-GWSR-------YIPEGMQCSCGID
YYTLKPEVNNESFVIYMFVVHFTIPMIVIFFCYGQLVFTVKEAAAQQQESA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TTQKAEKEVTRMVIIMVIFFLICWLPYASVAMYIFT-HQG-SN-FG
PIFMTLPAFFAKTASIYNPIIYIMMNKQFRNCMLTSLCC---------------------
------------------------------------------------------------
-----------------------------------------GKN-PLGDDE-ASA----T
ASKTE-----------------------TSQV-------------------------A--
--------------------------------------PA
> 3== M92038 1 chicken green sensitive cone opsin <retina>[PNAS89,5932-5936'9
M-----------------------------------------------------------
---NG------------TEGINFYVPMSNKTGVVR-------------------------
----------------------------------SP---------------------FEY
--------------------PQY---------------------YLAEPW----------
-----------KYRLVCCYIFFLISTGLPINLLTLLVTFKHKKLRQPLNYILVNLAVADL
FMACFG-FTVTFYTAWN-GYFV--FGPVGCAVEGFFATLGGQVALWSLVVLAIERYIVVC
KPMGNFRF-SATHAMMGIAFTWVMAFSC-AAPPLF-GWSR-------YMPEGMQCSCGPD
YYTHNPDYHNESYVLYMFVIHFIIPVVVIFFSYGRLICKVREAAAQQQESA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TTQKAEKEVTRMVILMVLGFMLAWTPYAVVAFWIFT-NKG-AD-FT
ATLMAVPAFFSKSSSLYNPIIYVLMNKQFRNCMITTICC---------------------
------------------------------------------------------------
-----------------------------------------GKN-PFGDEDVSST---VS
QSKTE------------------VSSVSSSQV-------------------------S--
--------------------------------------PA
> 4=p A45229 opsin, green-sensitive (clone GFgr-1) - goldfish
M-----------------------------------------------------------
---NG------------TEGKNFYVPMSNRTGLVR-------------------------
----------------------------------SP---------------------FEY
--------------------PQY---------------------YLAEPW----------
-----------QFKILALYLFFLMSMGLPINGLTLVVTAQHKKLRQPLNFILVNLAVAGT
IMVCFG-FTVTFYTAIN-GYFV--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVC
KPMGSFKF-SSSHAFAGIAFTWVMALAC-AAPPLF-GWSR-------YIPEGMQCSCGPD
YYTLNPDYNNESYVIYMFVCHFILPVAVIFFTYGRLVCTVKAAAAQQQDSA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEREVTKMVILMVFGFLIAWTPYATVAAWIFF-NKG-AD-FS
AKFMAIPAFFSKSSALYNPVIYVLLNKQFRNCMLTTIFC---------------------
------------------------------------------------------------
-----------------------------------------GKN-PLGDDE-SST---VS
TSKTE------------------VSS-----V-------------------------S--
--------------------------------------PA
> 5=p B45229 opsin, green-sensitive (clone GFgr-2) - goldfish
M-----------------------------------------------------------
---NG------------TEGNNFYVPLSNRTGLVR-------------------------
----------------------------------SP---------------------FEY
--------------------PQY---------------------YLAEPW----------
-----------QFKLLAVYMFFLICLGLPINGLTLICTAQHKKLRQPLNFILVNLAVAGA
IMVCFG-FTVTFYTAIN-GYFA--LGPTGCAVEGFMATLGGEVALWSLVVLAIERYIVVC
KPMGSFKF-SSTHASAGIAFTWVMAMAC-AAPPLV-GWSR-------YIPEGIQCSCGPD
YYTLNPEYNNESYVLYMFICHFILPVTIIFFTYGRLVCTVKAAAAQQQDSA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEREVTKMVILMVLGFLVAWTPYATVAAWIFF-NKG-AA-FS
AQFMAIPAFFSKTSALYNPVIYVLLNKQFRSCMLTTLFC---------------------
------------------------------------------------------------
-----------------------------------------GKN-PLGDEE-SST---VS
TSKTE------------------VSS-----V-------------------------S--
--------------------------------------PA
> 6== L11864 1 Carassius auratus blue cone opsin <retina>[Biochemistry32,208-
MK----------------------------------------------------------
-----------------------------------QVPEF--------------------
---------------HEDFYIPIPL-DINNLSAYSP---------------------FLV
--------------------PQD---------------------HLGNQG----------
-----------IFMAMSVFMFFIFIGGASINILTILCTIQFKKLRSHLNYILVNLSIANL
FVAIFG-SPLSFYSFFN-RYFI--FGATACKIEGFLATLGGMVGLWSLAVVAFERWLVIC
KPLGNFTF-KTPHAIAGCILPWISALAA-SLPPLF-GWSR-------YIPEGLQCSCGPD
WYTTNNKYNNESYVMFLFCFCFAVPFGTIVFCYGQLLITLKLAAKAQADSA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEREVTKMVVVMVLGFLVCWAPYASFSLWIVS-HRG-EE-FD
LRMATIPSCLSKASTVYNPVIYVLMNKQFRSCMMKMVC----------------------
------------------------------------------------------------
-----------------------------------------GKN--IEEDE-AST----S
SQVTQ------------------VSSVAP-------------------------------
--------------------------------------EK
> 7== M13299 1 human BCP <>[Science232(4747),193-202'86]
M-----------------------------------------------------------
----------------------------------RKMSE---------------------
----------------EEFYL------FKNISSVGP---------------------WDG
--------------------PQY---------------------HIAPVW----------
-----------AFYLQAAFMGTVFLIGFPLNAMVLVATLRYKKLRQPLNYILVNVSFGGF
LLCIFS-VFPVFVASCN-GYFV--FGRHVCALEGFLGTVAGLVTGWSLAFLAFERYIVIC
KPFGNFRF-SSKHALTVVLATWTIGIGV-SIPPFF-GWSR-------FIPEGLQCSCGPD
WYTVGTKYRSESYTWFLFIFCFIVPLSLICFSYTQLLRALKAVAAQQQESA---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TTQKAEREVSRMVVVMVGSFCVCYVPYAAFAMYMVN-NRN-HG-LD
LRLVTIPSFFSKSACIYNPIIYCFMNKQFQACIMKMVC----------------------
------------------------------------------------------------
-----------------------------------------GKA--MTDES-DTC----S
SQKTE------------------VSTVSSTQV-------------------------G--
--------------------------------------PN
> 8=opsin, greensensitive human (fragment) S07060
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------------------------DL
AETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVC
KPFGNVRF-DAKLAIVGIAFSWIWAAVW-TAPPIF-GWSR-------YWPHGLKTSCGPD
VFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEKEVTRMVVVMVLAFC-------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
----------------------------------------
> 9== K03494 1 human GCP <>[Science232(4747),193-202'86]
MAQQWSLQRLA------GRHPQDSYEDSTQS-------------------SIFTYTNS--
---NS------------TR-----------------------------------------
----------------------------------GP---------------------FEG
--------------------PNY---------------------HIAPRW----------
-----------VYHLTSVWMIFVVIASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADL
AETVIA-STISVVNQVY-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWMVVC
KPFGNVRF-DAKLAIVGIAFSWIWAAVW-TAPPIF-GWSR-------YWPHGLKTSCGPD
VFSGSSYPGVQSYMIVLMVTCCITPLSIIVLCYLQVWLAIRAVAKQQKESE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEKEVTRMVVVMVLAFCFCWGPYAFFACFAAA-NPG-YP-FH
PLMAALPAFFAKSATIYNPVIYVFMNRQFRNCILQLF-----------------------
------------------------------------------------------------
-----------------------------------------GKK--VDDGS-ELS----S
ASKTE------------------VSSV--SSV-------------------------S--
--------------------------------------PA
> 10== Z68193 1 human Red Opsin <>[]
MAQQWSLQRLA------GRHPQDSYEDSTQS-------------------SIFTYTNS--
---NS------------TR-----------------------------------------
----------------------------------GP---------------------FEG
--------------------PNY---------------------HIAPRW----------
-----------VYHLTSVWMIFVVTASVFTNGLVLAATMKFKKLRHPLNWILVNLAVADL
AETVIA-STISIVNQVS-GYFV--LGHPMCVLEGYTVSLCGITGLWSLAIISWERWLVVC
KPFGNVRF-DAKLAIVGIAFSWIWSAVW-TAPPIF-GWSR-------YWPHGLKTSCGPD
VFSGSSYPGVQSYMIVLMVTCCIIPLAIIMLCYLQVWLAIRAVAKQQKESE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEKEVTRMVVVMIFAYCVCWGPYTFFACFAAA-NPG-YA-FH
PLMAALPAYFAKSATIYNPVIYVFMNRQFRNCILQLF-----------------------
------------------------------------------------------------
-----------------------------------------GKK--VDDGS-ELS----S
ASKTE------------------VSSV--SSV-------------------------S--
--------------------------------------PA
> 11== M92036 1 Gecko gecko P521 <retina>[PNAS89,6841-6845'92]
MTEAWNV--------------------------AVFAARRSRDDDDTTRGSVFTYTNT--
---NN------------TR-----------------------------------------
----------------------------------GP---------------------FEG
--------------------PNY---------------------HIAPRW----------
-----------VYNLVSFFMIIVVIASCFTNGLVLVATAKFKKLRHPLNWILVNLAFVDL
VETLVA-STISVFNQIF-GYFI--LGHPLCVIEGYVVSSCGITGLWSLAIISWERWFVVC
KPFGNIKF-DSKLAIIGIVFSWVWAWGW-SAPPIF-GWSR-------YWPHGLKTSCGPD
VFSGSVELGCQSFMLTLMITCCFLPLFIIIVCYLQVWMAIRAVAAQQKESE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEREVSRMVVVMIVAFCICWGPYASFVSFAAA-NPG-YA-FH
PLAAALPAYFAKSATIYNPVIYVFMNRQFRNCIMQLF-----------------------
------------------------------------------------------------
-----------------------------------------GKK--VDDGS-EAS----T
TSRTE------------------VSSVSNSSV-------------------------A--
--------------------------------------PA
> 12== M62903 1 chicken visual pigment <>[BBRC173,1212-1217'90]
MA----------------------------AWEAAFAARRRHEEEDTTRDSVFTYTNS--
---NN------------TR-----------------------------------------
----------------------------------GP---------------------FEG
--------------------PNY---------------------HIAPRW----------
-----------VYNLTSVWMIFVVAASVFTNGLVLVATWKFKKLRHPLNWILVNLAVADL
GETVIA-STISVINQIS-GYFI--LGHPMCVVEGYTVSACGITALWSLAIISWERWFVVC
KPFGNIKF-DGKLAVAGILFSWLWSCAW-TAPPIF-GWSR-------YWPHGLKTSCGPD
VFSGSSDPGVQSYMVVLMVTCCFFPLAIIILCYLQVWLAIRAVAAQQKESE---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------STQKAEKEVSRMVVVMIVAYCFCWGPYTFFACFAAA-NPG-YA-FH
PLAAALPAYFAKSATIYNPIIYVFMNRQFRNCILQLF-----------------------
------------------------------------------------------------
-----------------------------------------GKK--VDDGS-EVS----T
-SRTE------------------VSSVSNSSV-------------------------S--
--------------------------------------PA
> 13== S75720 1 chicken P-opsin <>[Science267(5203),1502-1506'95]
MS-----------------------------------------------------SNSSQ
APPNG------------TP-----------------------------------------
----------------------------------GP---------------------FDG
--------------------PQW--------------------PYQAPQS----------
-----------TYVGVAVLMGTVVACASVVNGLVIVVSICYKKLRSPLNYILVNLAVADL
LVTLCG-SSVSLSNNIN-GFFV--FGRRMCELEGFMVSLTGIVGLWSLAILALERYVVVC
KPLGDFQF-QRRHAVSGCAFTWGWALLW-SAPPLL-GWSS-------YVPEGLRTSCGPN
WYTGGSN--NNSYILSLFVTCFVLPLSLILFSYTNLLLTLRAAAAQQKEAD---------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------TTQRAEREVTRMVIVMVMAFLLCWLPYSTFALVVAT-HKG-II-IQ
PVLASLPSYFSKTATVYNPIIYVFMNKQFQSCLLEMLCCGYQ------------------
------------------------------------------------------------
-------------------------------------PQRTGK-----------------
---------------------------------------------------------ASP
GTPGPHADVTAAGLRNKVMP----------------AHPV
> 14== M17718 1 D.melanogaster Rh3 <>[J.Neurosci.7,1550-1557'87]
ME-----------------------------------------------------SGNVS
SSLFG------------NV----STA----------------------------------
-------------------------------------LRPEARLSA--------ETRL--
--------------LGW-----------------NV--PPEELRHIPEHWLTYPEPPE--
----------SMNYLLGTLYIFFTLMSMLGNGLVIWVFSAAKSLRTPSNILVINLAFCDF
MMMVK--TPIFIYNSFH-QGYA--LGHLGCQIFGIIGSYTGIAAGATNAFIAYDRFNVIT
RPMEGK-M-THGKAIAMIIFIYMYATPW-VVACYTETWGR-------FVPEGYLTSCTFD
YLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVESLRSN--------------------------------------------------
-----------VDKNKETAEIRIAKAAITICFLFFCSWTPYGVMSLIGAF-GDK-TL-LT
PGATMIPACACKMVACIDPFVYAISHPRYRMELQKRCPWLA-------------------
------------------------------------------------------------
----------------------------------------LNE--KAPES--SAV---AS
TSTTQ----------------------EPQQT-------------------------T--
--------------------------------------AA
> 15== X65879 1 Drosophila pseudoobscura Dpse\Rh3 <>[Genetics132(1),193-204'92
MEYHNVSSVLGNVSSV--------------------------------------------
------------------------------------------------------------
-------------------------------------LRPDARLSA--------ESRL--
--------------LGW-----------------NV--PPDELRHIPEHWLIYPEPPE--
----------SMNYLLGTLYIFFTVISMIGNGLVMWVFSAAKSLRTPSNILVINLAFCDF
MMMIK--TPIFIYNSFH-QGYA--LGHLGCQIFGVIGSYTGIAAGATNAFIAYDRYNVIT
RPMEGK-M-THGKAIAMIIFIYLYATPW-VVACYTESWGR-------FVPEGYLTSCTFD
YLTDN--FDTRLFVACIFFFSFVCPTTMITYYYSQIVGHVFSHEKALRDQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVDSLRSN--------------------------------------------------
-----------VDKSKEAAEIRIAKAAITICFLFFASWTPYGVMSLIGAF-GDK-TL-LT
PGATMIPACTCKMVACIDPFVYAISHPRYRMELQKRCPWLA-------------------
------------------------------------------------------------
----------------------------------------ISE--KAPES--RAA---IS
TSTTQ----------------------EQQQT-------------------------T--
--------------------------------------AA
> 16== M17730 1 D.melanogaster Rh4 opsin <>[J.Neurosci.7,1558-1566'87]
ME----------------------------------------------------------
-------------------------PLC-------NAS----------------------
----------------------------------EPPLRPEAR-SSG-----NGDLQF--
--------------LGW-----------------NV--PPDQIQYIPEHWLTQLEPPA--
----------SMHYMLGVFYIFLFCASTVGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDL
IMCLK--APIF--NSFH-RGFAIYLGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVIT
KPMNRN-M-TFTKAVIMNIIIWLYCTPW-VVLPLTQFWDR-------FVPEGYLTSCSFD
YLSDN--FDTRLFVGTIFFFSFVCPTLMILYYYSQIVGHVFSHEKALREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVESLRSN--------------------------------------------------
-----------VDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDK-SL-LT
QGATMIPACTCKLVACIDPFVYAISHPRYRLELQKRCPWLG-------------------
------------------------------------------------------------
----------------------------------------VNE--KSGEI--SSA---QS
TTTQE----------------------Q-QQT-------------------------T--
--------------------------------------AA
> 17== X65880 1 Drosophila pseudoobscura Dpse\Rh4 <>[Genetics132(1),193-204'92
MD----------------------------------------------------------
-------------------------ALC-------NAS----------------------
----------------------------------EPPLRPEARMSSG-----SDELQF--
--------------LGW-----------------NV--PPDQIQYIPEHWLTQLEPPA--
----------SMHYMLGVFYIFLFFASTLGNGMVIWIFSTSKSLRTPSNMFVLNLAVFDL
IMCLK--APIFIYNSFH-RGFA--LGNTWCQIFASIGSYSGIGAGMTNAAIGYDRYNVIT
KPMNRN-M-TFTKAVIMNIIIWLYCTPW-VVLPLTQFWDR-------FVPEGYLTSCSFD
YLSDN--FDTRLFVGTIFLFSFVVPTLMILYYYSQIVGHVFNHEKALREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVESLRSN--------------------------------------------------
-----------VDKSKETAEIRIAKAAITICFLFFVSWTPYGVMSLIGAF-GDK-SL-LT
PGATMIPACTCKLVACIEPFVYAISHPRYRMELQKRCPWLG-------------------
------------------------------------------------------------
----------------------------------------VNE--KSGEA--SSA---QS
TTTQE----------------------QTQQT-------------------------S--
--------------------------------------AA
> 18== D50584 1 Hemigrapsus sanguineus opsin BcRh2 <compound eye>[J.Exp.Biol.1
MT----------------------------------------------------------
-----------------------------------NAT----------------------
----------------------------------GP------------------QMAYYG
A-----------ASMDFGY-P------EGVSIVDFV--RPEIKPYVHQHWYNYPPVNP--
----------MWHYLLGVIYLFLGTVSIFGNGLVIYLFNKSAALRTPANILVVNLALSDL
IMLTTN-VPFFTYNCFSGGVWM--FSPQYCEIYACLGAITGVCSIWLLCMISFDRYNIIC
NGFNGPKL-TTGKAVVFALISWVIAIGC-ALPPFF-GWGN-------YILEGILDSCSYD
YLTQD--FNTFSYNIFIFVFDYFLPAAIIVFSYVFIVKAIFAHEAAMRAQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVSTLRS---------------------------------------------------
-----------NEADAQRAEIRIAKTALVNVSLWFICWTPYALISLKGVM-GDT-SG-IT
PLVSTLPALLAKSCSCYNPFVYAISHPKYRLAITQHLPWFC-------------------
------------------------------------------------------------
----------------------------------------VHE-----------------
----------------------------------------TETKSNDDSQSNSTVAQD--
--------------------------------------KA
> 19== D50583 1 Hemigrapsus sanguineus opsin BcRh1 <compound eye>[J.Exp.Biol.1
MA----------------------------------------------------------
-----------------------------------NVT----------------------
----------------------------------GP------------------QMAFYG
S-----------GAATFGY-P------EGMTVADFV--PDRVKHMVLDHWYNYPPVNP--
----------MWHYLLGVVYLFLGVISIAGNGLVIYLYMKSQALKTPANMLIVNLALSDL
IMLTTN-FPPFCYNCFSGGRWM--FSGTYCEIYAALGAITGVCSIWTLCMISFDRYNIIC
NGFNGPKL-TQGKATFMCGLAWVISVGW-SLPPFF-GWGS-------YTLEGILDSCSYD
YFTRD--MNTITYNICIFIFDFFLPASVIVFSYVFIVKAIFAHEAAMRAQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVTNLRS---------------------------------------------------
-----------NEAETQRAEIRIAKTALVNVSLWFICWTPYAAITIQGLL-GNA-EG-IT
PLLTTLPALLAKSCSCYNPFVYAISHPKFRLAITQHLPWFC-------------------
------------------------------------------------------------
----------------------------------------VHE--KDPNDV---------
---------------------------EENQS------SNTQT-------------QE--
--------------------------------------KS
> 20== K02320 1 D.melanogaster opsin <>[Cell40,851-858'85]
ME----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------SFAVAAAQLG---
--------------------PHFAP-LSNGSVVDKV--TPDMAHLISPYWNQFPAMDP--
----------IWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGRPM-TIPLALGKM-----------------------------YVPEGNLTSCGID
YLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVKSLRS---------------------------------------------------
-----------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LT
PLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV-------------------
------------------------------------------------------------
----------------------------------------FG------------------
-------------------------------KVDDGKSSDAQS------QATASEAES--
--------------------------------------KA
> 21== K02315 1 D.melanogaster ninaE <>[Cell40,839-850'85]
ME----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------SFAVAAAQLG---
--------------------PHFAP-LSNGSVVDKV--TPDMAHLISPYWNQFPAMDP--
----------IWAKILTAYMIMIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGRPM-TIPLALGKIAYIWFMSSIW-CLAPAF-GWSR-------YVPEGNLTSCGID
YLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVKSLRS---------------------------------------------------
-----------SEDAEKSAEGKLAKVALVTITLWFMAWTPYLVINCMGLF--KF-EG-LT
PLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV-------------------
------------------------------------------------------------
----------------------------------------FG------------------
-------------------------------KVDDGKSSDAQS------QATASEAES--
--------------------------------------KA
> 22== X65877 1 Drosophila pseudoobscura Dpse\ninaE <>[Genetics132(1),193-204'
MD----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------SFAAVATQLG---
--------------------PQFAA-PSNGSVVDKV--TPDMAHLISPYWDQFPAMDP--
----------IWAKILTAYMIIIGMISWCGNGVVIYIFATTKSLRTPANLLVINLAISDF
GIMITN-TPMMGINLYF-ETWV--LGPMMCDIYAGLGSAFGCSSIWSMCMISLDRYQVIV
KGMAGRPM-TIPLALGKIAYIWFMSTIWCCLAPVF-GWSR-------YVPEGNLTSCGID
YLERD--WNPRSYLIFYSIFVYYIPLFLICYSYWFIIAAVSAHEKAMREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVKSLRS---------------------------------------------------
-----------SEDADKSAEGKLAKVALVTISLWFMAWTPYLVINCMGLF--KF-EG-LT
PLNTIWGACFAKSAACYNPIVYGISHPKYRLALKEKCPCCV-------------------
------------------------------------------------------------
----------------------------------------FG------------------
-------------------------------KVDDGKSSEAQS------QATTSEAES--
--------------------------------------KA
> 23== M12896 1 D.melanogaster Rh2 <>[Cell44,705-710'86]
MERSHLPET---------------------------------------------------
-------------------------PFD------LAHS----------------------
----------------------------------GP--RFQAQ-SSG-------------
----------------------------NGSVLDNV--LPDMAHLVNPYWSRFAPMDP--
----------MMSKILGLFTLAIMIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDF
CMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAGCGSLFGCVSIWSMCMIAFDRYNVIV
KGINGTPM-TIKTSIMKILFIWMMAVFW-TVMPLI-GWSA-------YVPEGNLTACSID
YMTRM--WNPRSYLITYSLFVYYTPLFLICYSYWFIIAAVAAHEKAMREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVKSLRS---------------------------------------------------
-----------SEDCDKSAEGKLAKVALTTISLWFMAWTPYLVICYFGLF--KI-DG-LT
PLTTIWGATFAKTSAVYNPIVYGISHPKYRIVLKEKCPMCV-------------------
------------------------------------------------------------
----------------------------------------FGN-----------------
--TDEPKPDAPA---------------SDTE--------------------TTSEADS--
--------------------------------------KA
> 24== X65878 1 Drosophila pseudoobscura Dpse\Rh2 <>[Genetics132(1),193-204'92
MERSLLPEP---------------------------------------------------
-------------------------PLA------MALL----------------------
----------------------------------GP--RFEAQ-TGG-------------
----------------------------NRSVLDNV--LPDMAPLVNPHWSRFAPMDP--
----------TMSKILGLFTLVILIISCCGNGVVVYIFGGTKSLRTPANLLVLNLAFSDF
CMMASQ-SPVMIINFYY-ETWV--LGPLWCDIYAACGSLFGCVSIWSMCMIAFDRYNVIV
KGINGTPM-TIKTSIMKIAFIWMMAVFW-TIMPLI-GWSS-------YVPEGNLTACSID
YMTRQ--WNPRSYLITYSLFVYYTPLFMICYSYWFIIATVAAHEKAMRDQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVKSLRS---------------------------------------------------
-----------SEDCDKSAENKLAKVALTTISLWFMAWTPYLIICYFGLF--KI-DG-LT
PLTTIWGATFAKTSAVYNPIVYGISHPNDRLVLKEKCPMCV-------------------
------------------------------------------------------------
----------------------------------------CGT-----------------
--TDEPKPDAPP---------------SDTE--------------------TTSEAES--
--------------------------------------KD
> 25== U26026 1 Apis mellifera long-wavelength rhodopsin <>[]
MI----------------------------------------------------------
-----------------------------------AVS----------------------
----------------------------------GP--SYEAF-SYGGQARFNNQ-----
------------------------------TVVDKV--PPDMLHLIDANWYQYPPLNP--
----------MWHGILGFVIGMLGFVSAMGNGMVVYIFLSTKSLRTPSNLFVINLAISNF
LMMFCM-SPPMVINCYY-ETWV--LGPLFCQIYAMLGSLFGCGSIWTMTMIAFDRYNVIV
KGLSGKPL-SINGALIRIIAIWLFSLGW-TIAPMF-GWNR-------YVPEGNMTACGTD
YFNRG--LLSASYLVCYGIWVYFVPLFLIIYSYWFIIQAVAAHEKNMREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVASLRS---------------------------------------------------
-----------SENQNTSAECKLAKVALMTISLWFMAWTPYLVINFSGIF--NL-VK-IS
PLFTIWGSLFAKANAVYNPIVYGISHPKYRAALFAKFPSLA-------------------
------------------------------------------------------------
----------------------------------------CAA-----------------
-----------EPSSDAVSTTSGTTTVTDNEK-------------------------S--
--------------------------------------NA
> 26== L03781 1 Limulus polyphemus opsin <>[PNAS90,6150-6154'93]
MA----------------------------------------------------------
------------------------------------------------------------
-----------------------------------------------------NQLSY--
------------SSLGWPYQP-------NASVVDTM--PKEMLYMIHEHWYAFPPMNP--
----------LWYSILGVAMIILGIICVLGNGMVIYLMMTTKSLRTPTNLLVVNLAFSDF
CMMAFM-MPTMTSNCFA-ETWI--LGPFMCEVYGMAGSLFGCASIWSMVMITLDRYNVIV
RGMAAAPL-THKKATLLLLFVWIWSGGW-TILPFF-GWSR-------YVPEGNLTSCTVD
YLTKD--WSSASYVVIYGLAVYFLPLITMIYCYFFIVHAVAEHEKQLREQAKK-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-MNVASLRAN--------------------------------------------------
-----------ADQQKQSAECRLAKVAMMTVGLWFMAWTPYLIISWAGVF-SSG-TR-LT
PLATIWGSVFAKANSCYNPIVYGISHPRYKAALYQRFPSLA-------------------
------------------------------------------------------------
----------------------------------------CGSG-ESGSDVKSEA---SA
TTTMEEKPKIP-------------------------------------------------
--------------------------------------EA
> 27== X07797 1 Octopus dofleini rhodopsin <>[FEBS232(1),69-72'88]
MV----------------------------------------------------------
-----------------------------------ESTT---------------------
-----LVNQT--------------------------------------------------
----------------WWYNPTV---------------------DIHPHWAKFDPIPD--
----------AVYYSVGIFIGVVGIIGILGNGVVIYLFSKTKSLQTPANMFIINLAMSDL
SFSAINGFPLKTISAFM-KKWI--FGKVACQLYGLLGGIFGFMSINTMAMISIDRYNVIG
RPMAASKKMSHRRAFLMIIFVWMWSIVW-SVGPVF-NWGA-------YVPEGILTSCSFD
YLSTD--PSTRSFILCMYFCGFMLPIIIIAFCYFNIVMSVSNHEKEMAAMAKR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LNAKELRKA--------------------------------------------------
-------------QAGASAEMKLAKISMVIITQFMLSWSPYAIIALLAQF-GPA-EW-VT
PYAAELPVLFAKASAIHNPIVYSVSHPKFREAIQTTFPWLLTCCQFDEKECED-------
------------ANDAEEEVVASERGGESRDAAQMKEMMAMMQKMQAQQAAYQP---PPP
PQGYPPQGYPPQGAYPPPQGYPPQGYPPQGYPPQGYPPQ---------------------
------------------------------------------------------------
GAP----------------PQVEAPQGAPPQGVDNQAYQA
> 28== X70498 1 Todarodes pacificus rhodopsin <retina>[FEBS317(1-2),5-11'93]
MGR-----------------------DLRD------------------------------
------------------------------------------------------------
-------NET--------------------------------------------------
----------------WWYNPSI---------------------VVHPHWREFDQVPD--
----------AVYYSLGIFIGICGIIGCGGNGIVIYLFTKTKSLQTPANMFIINLAFSDF
TFSLVNGFPLMTISCFL-KKWI--FGFAACKVYGFIGGIFGFMSIMTMAMISIDRYNVIG
RPMAASKKMSHRRAFIMIIFVWLWSVLW-AIGPIF-GWGA-------YTLEGVLCNCSFD
YISRD--STTRSNILCMFILGFFGPILIIFFCYFNIVMSVSNHEKEMAAMAKR-------
------------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
-LNAKELRKA--------------------------------------------------
-------------QAGANAEMRLAKISIVIVSQFLLSWSPYAVVALLAQF-GPL-EW-VT
PYAAQLPVMFAKASAIHNPMIYSVSHPKFREAISQTFPWVLTCCQFDDKETEDDKDAETE
IPAGESSDAAPSA-----------------DAAQMKEMMAMMQKMQQQQAAYPPQGYAPP
PQGYPPQGYPPQGY--PPQGYPPQGYPP---PPQGAPPQ---------------------
------------------------------------------------------------
GAP----------------P------AAPPQGVDNQAYQA
> 29== L21195 1 human serotonin 5-HT7 receptor protein <placenta and fetal bra
MMDV--------------------------------------------------------
-NSSGRPDLYGHLRSFLLPEVGRGLPDLSPDGGA--------------------------
----------------------------------DP--------VAGS------------
----------------WA--PHLLS---EVTASPAPTW--------------DAPPDNAS
GCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWAQ-------NVNDDKVCLISQD
F----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP---G------
-----FPRVEPDSVIALNGI----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
V--------------KLQKEV------------------EECAN----------------
--LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIP
LWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----------------------
------------------------------------------------------------
-----------------------------------------CQYRNINRKL-SAAGMHEA
LKLAE-RPERPE----FVLQ---NADYCRKKG-------------------------H--
--------------------------------------DS
> 30== L15228 1 rat 5HT-7 serotonin receptor <>[JBC268,18200-18204'93]
M-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------PHLLSGFLEVTASPAPTW--------------DAPPDNVS
GCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWAQ-------NVNDDKVCLISQD
F----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP---G------
-----FPRVQPESVISLNGV----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
V--------------KLQKEV------------------EECAN----------------
--LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIP
LWVERTCLWLGYANSLINPFIYAFFNRDLRPTSRSLLQ----------------------
------------------------------------------------------------
-----------------------------------------CQYRNINRKL-SAAGMHEA
LKLAE-RPERSE----FVLQ---NSDHCGKKG-------------------------H--
--------------------------------------DT
> 31=p A47425 serotonin receptor 5HT-7 - rat
M-----------------------------------------------------------
------------------------------------------------------------
------------------------------------------------------------
--------------------PHLLSGFLEVTASPAPTW--------------DAPPDNVS
GCGEQINYGRVEKVVIGSILTLITLLTIAGNCLVVISVSFVKKLRQPSNYLIVSLALADL
SVAVAV-MPFVSVTDLIGGKWI--FGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGIT
RPLTYPVRQNGKCMAKMILSVWLLSASI-TLPPLF-GWAQ-------NVNDDKVCLISQD
F----------GYTIYSTAVAFYIPMSVMLFMYYQIYKAARKSAAKHKFP---G------
-----FPRVQPESVISLNGV----------------------------------------
------------------------------------------------------------
------------------------------------------------------------
V--------------KLQKEV------------------EECAN----------------
--LSRLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIP
LWVERTCLWLGYANSLINPFIYAFFNRDLRTTYRSLLQ----------------------
------------------------------------------------------------
-----------------------------------------CQYRNINRKL-SAAGMHEA
LKLAE-RPERSE----FVLQ---NSDHCGKKG-------------------------H--
--------------------------------------DT
> 32== M83181 1 human serotonin receptor <>[JBC267(11),7553-7562'92]
MDVLSPG-----------------------------------------------------
------------------------------------------------------------
-----QGNNTT--------------------SPPAP------FETGG-------------
----------------------------NTTGISDVTV----------------------
----------SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL
MVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAIT
DPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTP--EDRSDPD---ACTISKD
H----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK--------------
-------------------------TVKKVEKTG--------------------------
-------------ADTRHGASPAPQPKKSVNGESGSRNWRLGVESKAGGALCANGAVRQG
DDGAALEVIEVHRVGNSKEHLPLPSEAGPTPCAPASFERKNER-----------------
--------------------NAEA------------------------------------
-----------KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MP
TLLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----------------------
------------------------------------------------------------
-----------------------------------------CKF----------------
---------------------------CR-------------------------------
---------------------------------------Q
> 33=p A35181 serotonin receptor class 1A - rat
MDVFSFG-----------------------------------------------------
------------------------------------------------------------
-----QGNNTT--------------------ASQEP------FGTGG-------------
----------------------------NVTSISDVTF----------------------
----------SYQVITSLLLGTLIFCAVLGNACVVAAIALERSLQNVANYLIGSLAVTDL
MVSVLV-LPMAALYQVL-NKWT--LGQVTCDLFIALDVLCCTSSILHLCAIALDRYWAIT
DPIDYVNKRTPRRAAALISLTWLIGFLI-SIPPML-GWRTP--EDRSDPD---ACTISKD
H----------GYTIYSTFGAFYIPLLLMLVLYGRIFRAARFRIRK--------------
-------------------------TVRKVEKKGAGTSLGTSSAPPPKKSLNGQPGSGDW
RRCAENRAVGTP---------------------------------------CTNGAVRQG
DDEATLEVIEVHRVGNSKEHLPLPSESGSNSYAPACLERKNER-----------------
--------------------NAEA------------------------------------
-----------KRKMALARERKTVKTLGIIMGTFILCWLPFFIVALVLPF-CESSCH-MP
ALLGAIINWLGYSNSLLNPVIYAYFNKDFQNAFKKIIK----------------------
------------------------------------------------------------
-----------------------------------------CKF----------------
---------------------------CR-------------------------------
---------------------------------------R
> 34== L06803 1 Lymnaea stagnalis serotonin receptor <>[PNAS90,11-15'93]
MANFTFGDLALDVARMGGL----------------------------------------A
STPSG------------LRSTGLTTPGLSPTGLV----TSDFNDSYGLTGQFINGSHSSR
SRDNASANDTSATNMTDDRYWSLTVYSHEHL-----------------------------
------------------------------------------------------------
-------------VLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADL
MVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVT
S-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NN--DPDKTGTCIISQD
K----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEE
TTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRP---------------
------------------------------------------------------------
-------------------------------------ERKKNRAKKLPENANG-------
---VNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS----
---------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP-EG-IP
PFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----------------------
------------------------------------------------------------
-----------------------------------------GKY----------------
------------------------------RR-------------------------G--
--------------------------------------HR
> 35=p A47174 serotonin receptor, 5HTlym receptor - great pond snail
MANFTFGDLALDVARMGGL----------------------------------------A
STPSG------------LRSTGLTTPGLSPTGLV----TSDFNDSYGLTGQFINGSHSSR
SRDNASANDTSATNMTDDRYWSLTVYSHEHL-----------------------------
------------------------------------------------------------
-------------VLTSVILGLFVLCCIIGNCFVIAAVMLERSLHNVANYLILSLAVADL
MVAVLV-MPLSVVSEIS-KVWF--LHSEVCDMWISVDVLCCTASILHLVAIAMDRYWAVT
S-IDYIRRRSARRILLMIMVVWIVALFI-SIPPLF-GWRDP--NN--DPDKTGTCIISQD
K----------GYTIFSTVGAFYLPMLVMMIIYIRIWLVARSRIRKDKFQMTKARLKTEE
TTLVASPKTEYSVVSDCNGCNSPDSTTEKKKRRAPFKSYGCSPRP---------------
------------------------------------------------------------
-------------------------------------ERKKNRAKKLPENANG-------
---VNSNSSSSERLKQIQIETAEAFANGCAEEASIAMLERQCNNGKKISSNDTPYS----
---------RTREKLELKRERKAARTLAIITGAFLICWLPFFIIALIGPF-VDP-EG-IP
PFARSFVLWLGYFNSLLNPIIYTIFSPEFRSAFQKILF----------------------
------------------------------------------------------------
-----------------------------------------GKY----------------
------------------------------RR-------------------------G--
--------------------------------------HR
> 36== X95604 1 Bombyx mori serotonin receptor <antennae>[InsectBiochem.Mol.Bi
ME----------------------------------------------------------
------------------------------------------------------------
-------------------------------------------GAEG-----QEELDWEA
LYLRLPLQNCSWNSTGWE--PNW-----NVTVVPNTTW-----------WQASAPFDTPA
AL--------VRAAAKAVVLGLLILATVVGNVFVIAAILLERHLRSAANNLILSLAVADL
LVACLV-MPLGAVYEVV-QRWT--LGPELCDMWTSGDVLCCTASILHLVAIALDRYWAVT
N-IDYIHASTAKRVGMMIACVWTVSFFV-CIAQLL-GWKDPDWNQ--RVSEDLRCVVSQD
V----------GYQIFATASSFYVPVLIILILYWRIYQTARKRIRRRR------------
------------------------------------------------------------
------------GATARGGVGPPPVP--------------------AGGALVAGG----G
SGGIAAAVVAV--IGR-----PLPT---------------------------ISETTTTG
FTNVSSNNTSPEK--------------------------QSCANGLEADPPTTGYGAVAA
AYYPSLVRRKPKEAADSKRERKAAKTLAIITGAFVACWLPFFVLAILVPT-CD--CE-VS
PVLTSLSLWLGYFNSTLNPVIYTVFSPEFRHAFQRLLC----------------------
------------------------------------------------------------
-----------------------------------------GRR----------------
---------------------------VRRRR-------------------------A--
--------------------------------------PQ
|
