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Source: mosdepth
Section: science
Priority: optional
Maintainer: Debian Med Packaging Team <debian-med-packaging@lists.alioth.debian.org>
Uploaders: Steffen Moeller <moeller@debian.org>
Build-Depends: debhelper-compat (= 13),
nim,
nim-docopt-dev (>= 0.7.1-1~),
nim-regex-dev (>= 0.26.3+ds-1~),
nim-hts-dev (>= 0.3.25+ds-3~),
help2man,
samtools,
libhts-dev
Standards-Version: 4.7.2
Vcs-Browser: https://salsa.debian.org/med-team/mosdepth
Vcs-Git: https://salsa.debian.org/med-team/mosdepth.git
Homepage: https://github.com/brentp/mosdepth
Rules-Requires-Root: no
Package: mosdepth
Architecture: any
Depends: ${shlibs:Depends}, ${misc:Depends}, libhts-dev
Description: BAM/CRAM depth calculation biological sequencing
Many small reads are produced by high-throughput "next generation"
sequencing technologies. The final sequence is derived from how
these reads are overlapping towards a consensus.
The more reads are covering/confirming parts of a nucleotide seq,
the higher the confidence is. Too many reads would be indicative
of e.g. repeats in the genome.
.
mosdepth can output:
* per-base depth about 2x as fast samtools depth--about 25 minutes
of CPU time for a 30X genome.
* mean per-window depth given a window size--as would be used for
CNV calling.
* the mean per-region given a BED file of regions.
* a distribution of proportion of bases covered at or above a given
threshold for each chromosome and genome-wide.
* quantized output that merges adjacent bases as long as they fall
in the same coverage bins e.g. (10-20)
* threshold output to indicate how many bases in each region are
covered at the given thresholds.
when appropriate, the output files are bgzipped and indexed for ease
of use.
Package: mosdepth-examples
Architecture: all
Depends: ${misc:Depends}
Multi-Arch: foreign
Description: Test data for mosdepth
Many small reads are produced by high-throughput "next generation"
sequencing technologies. The final sequence is derived from how
these reads are overlapping towards a consensus.
The more reads are covering/confirming parts of a nucleotide seq,
the higher the confidence is. Too many reads would be indicative
of e.g. repeats in the genome.
.
mosdepth can output:
* per-base depth about 2x as fast samtools depth--about 25 minutes
of CPU time for a 30X genome.
* mean per-window depth given a window size--as would be used for
CNV calling.
* the mean per-region given a BED file of regions.
* a distribution of proportion of bases covered at or above a given
threshold for each chromosome and genome-wide.
* quantized output that merges adjacent bases as long as they fall
in the same coverage bins e.g. (10-20)
* threshold output to indicate how many bases in each region are
covered at the given thresholds.
when appropriate, the output files are bgzipped and indexed for ease
of use.
.
This package contains a test data set as well as sample scripts
running some test suite provided by Debian also as autopkgtest.
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