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/*
* cmdargs.c
*
* $Id$
*
*****************************************************************************
*
* Copyright (c) 2004, Luke Sheneman
* All rights reserved.
*
* Redistribution and use in source and binary forms, with or without
* modification, are permitted provided that the following conditions
* are met:
*
* + Redistributions of source code must retain the above copyright
* notice, this list of conditions and the following disclaimer.
* + Redistributions in binary form must reproduce the above copyright
* notice, this list of conditions and the following disclaimer in
* the documentation and/or other materials provided with the
* distribution.
* + The names of its contributors may not be used to endorse or promote
* products derived from this software without specific prior
* written permission.
*
* THIS SOFTWARE IS PROVIDED BY THE COPYRIGHT HOLDERS AND CONTRIBUTORS "AS IS"
* AND ANY EXPRESS OR IMPLIED WARRANTIES, INCLUDING, BUT NOT LIMITED TO, THE
* IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE
* ARE DISCLAIMED. IN NO EVENT SHALL THE COPYRIGHT OWNER OR CONTRIBUTORS BE
* LIABLE FOR ANY DIRECT, INDIRECT, INCIDENTAL, SPECIAL, EXEMPLARY, OR
* CONSEQUENTIAL DAMAGES (INCLUDING, BUT NOT LIMITED TO, PROCUREMENT OF
* SUBSTITUTE GOODS OR SERVICES; LOSS OF USE, DATA, OR PROFITS; OR BUSINESS
* INTERRUPTION) HOWEVER CAUSED AND ON ANY THEORY OF LIABILITY, WHETHER IN
* CONTRACT, STRICT LIABILITY, OR TORT (INCLUDING NEGLIGENCE OR OTHERWISE)
* ARISING IN ANY WAY OUT OF THE USE OF THIS SOFTWARE, EVEN IF ADVISED OF THE
* POSSIBILITY OF SUCH DAMAGE.
*
*****************************************************************************
*
* AUTHOR:
*
* Luke Sheneman
* sheneman@cs.uidaho.edu
*
*/
#include <stdio.h>
#include <stdlib.h>
#include <string.h>
#include <time.h>
#ifdef USE_GNU
#include <getopt.h>
#else
#include "getopt_long.h"
#endif /* USE_GNU*/
#include "clearcut.h"
#include "cmdargs.h"
/*
* NJ_handle_args() -
*
*/
NJ_ARGS *
NJ_handle_args(int argc,
char *argv[]) {
static NJ_ARGS nj_args;
int option_index, c;
optind = 0; //neccasary to read in arguments if code is run more than once
struct option NJ_long_options[] = {
/* These options don't set a flag */
{"in", required_argument, NULL, 'i'},
{"out", required_argument, NULL, 'o'},
{"seed", required_argument, NULL, 's'},
{"matrixout", required_argument, NULL, 'm'},
{"ntrees", required_argument, NULL, 'n'},
/* These options set a flag */
{"verbose", no_argument, &(nj_args.verbose_flag), 1},
{"quiet", no_argument, &(nj_args.quiet_flag), 1},
{"distance", no_argument, &(nj_args.input_mode), NJ_INPUT_MODE_DISTANCE},
{"alignment", no_argument, &(nj_args.input_mode), NJ_INPUT_MODE_ALIGNED_SEQUENCES},
{"help", no_argument, &(nj_args.help), 1},
{"version", no_argument, &(nj_args.version), 1},
{"norandom", no_argument, &(nj_args.norandom), 1},
{"shuffle", no_argument, &(nj_args.shuffle), 1},
{"stdin", no_argument, &(nj_args.stdin_flag), 1},
{"stdout", no_argument, &(nj_args.stdout_flag), 1},
{"dna", no_argument, &(nj_args.dna_flag), 1},
{"DNA", no_argument, &(nj_args.dna_flag), 1},
{"protein", no_argument, &(nj_args.protein_flag), 1},
{"neighbor", no_argument, &(nj_args.neighbor), 1},
{"expblen", no_argument, &(nj_args.expblen), 1},
{"expdist", no_argument, &(nj_args.expdist), 1},
{"jukes", no_argument, &(nj_args.jukes_flag), 1},
{"kimura", no_argument, &(nj_args.kimura_flag), 1},
{0, 0, 0, 0}
};
/* initializes options to their default */
nj_args.infilename = NULL;
nj_args.outfilename = NULL;
nj_args.matrixout = NULL;
nj_args.seed = time(0);
nj_args.verbose_flag = 0;
nj_args.quiet_flag = 0;
nj_args.input_mode = NJ_INPUT_MODE_DISTANCE;
nj_args.help = 0;
nj_args.version = 0;
nj_args.norandom = 0;
nj_args.shuffle = 0;
nj_args.stdin_flag = 0;
nj_args.stdout_flag = 0;
nj_args.dna_flag = 0;
nj_args.protein_flag = 0;
nj_args.correction_model = NJ_MODEL_NONE;
nj_args.jukes_flag = 0;
nj_args.kimura_flag = 0;
nj_args.neighbor = 0;
nj_args.ntrees = 1;
nj_args.expblen = 0;
nj_args.expdist = 0;
while(1) {
c = getopt_long(argc,
argv,
"i:o:s:m:n:vqduahVSIOrDPjkNeE",
NJ_long_options,
&option_index);
if(c == -1) {
break;
}
//printf("%d\t%d\n", option_index, argc);
//for (int red = 0; red < argc; red++) { printf("%s\n", argv[red]); }
switch(c) {
case 0:
if(NJ_long_options[option_index].flag) {
break;
}
printf("option %s", NJ_long_options[option_index].name);
if(optarg) {
printf(" with arg %s", optarg);
}
printf("\n");
break;
case 'i':
nj_args.infilename = optarg;
break;
case 'o':
nj_args.outfilename = optarg;
break;
case 's':
nj_args.seed = atoi(optarg);
break;
case 'm':
nj_args.matrixout = optarg;
break;
case 'n':
nj_args.ntrees = atoi(optarg);
break;
case 'v':
nj_args.verbose_flag = 1;
break;
case 'q':
nj_args.quiet_flag = 1;
break;
case 'd':
nj_args.input_mode = NJ_INPUT_MODE_DISTANCE;
break;
case 'a':
nj_args.input_mode = NJ_INPUT_MODE_ALIGNED_SEQUENCES;
break;
case 'h':
nj_args.help = 1;
break;
case 'V':
nj_args.version = 1;
break;
case 'S':
nj_args.shuffle = 1;
break;
case 'I':
nj_args.stdin_flag = 1;
break;
case 'O':
nj_args.stdin_flag = 1;
break;
case 'r':
nj_args.norandom = 1;
break;
case 'D':
nj_args.dna_flag = 1;
break;
case 'P':
nj_args.protein_flag = 1;
break;
case 'j':
nj_args.jukes_flag = 1;
break;
case 'k':
nj_args.kimura_flag = 1;
break;
case 'N':
nj_args.neighbor = 1;
break;
case 'e':
nj_args.expblen = 1;
break;
case 'E':
nj_args.expdist = 1;
break;
default:
NJ_usage();
exit(-1);
}
}
if(optind < argc) {
fprintf(stderr, "Clearcut: Unknown command-line argument:\n --> %s\n", argv[optind]);
NJ_usage();
exit(-1);
}
if(nj_args.version) {
printf("Clearcut Version: %s\n", NJ_VERSION);
//exit(0);
}
if(nj_args.help) {
NJ_usage();
//exit(0);
}
/* if stdin & explicit filename are specified for input */
if(nj_args.stdin_flag) {
if(nj_args.infilename) {
fprintf(stderr, "Clearcut: Ambiguous input source specified. Specify input filename OR stdin.\n");
NJ_usage();
exit(-1);
}
}
/* if stdout & explicit filename are specified for output */
if(nj_args.stdout_flag) {
if(nj_args.outfilename) {
fprintf(stderr, "Clearcut: Ambiguous output specified. Specify output filename OR stdout.\n");
NJ_usage();
exit(-1);
}
}
/* if user did not specify stdin or filename, default to stdin */
if(!nj_args.stdin_flag) {
if(!nj_args.infilename) {
fprintf(stderr, "Clearcut: No input file specified. Using stdin.\n");
nj_args.stdin_flag = 1;
}
}
/* if user did not specify stdout or filename, default to stdout */
if(!nj_args.stdout_flag) {
if(!nj_args.outfilename) {
fprintf(stderr, "Clearcut: No output file specified. Using stdout.\n");
nj_args.stdout_flag = 1;
}
}
/* User must specify distance matrix or alignment */
if(nj_args.input_mode == NJ_INPUT_MODE_UNKNOWN) {
fprintf(stderr, "Clearcut: Must specify input type (--distance | --alignment)\n");
NJ_usage();
exit(-1);
}
/* do not allow protein or DNA options for distance matrix input */
if(nj_args.input_mode == NJ_INPUT_MODE_DISTANCE) {
if(nj_args.dna_flag || nj_args.protein_flag) {
fprintf(stderr, "Clearcut: Ambiguous arguments. (--protein | --DNA) do not apply to distance \n");
NJ_usage();
exit(-1);
}
}
/* make sure different filenames were specified for input and output */
if(!nj_args.stdin_flag && !nj_args.stdout_flag) {
if(!strcmp(nj_args.infilename, nj_args.outfilename)) {
fprintf(stderr, "Clearcut: Input filename and output filename must be unique.\n");
NJ_usage();
exit(-1);
}
}
/* make sure that user specifies DNA or Protein if dealing with alignment input */
if(nj_args.input_mode == NJ_INPUT_MODE_ALIGNED_SEQUENCES) {
if(!nj_args.dna_flag && !nj_args.protein_flag) {
fprintf(stderr, "Clearcut: Must specify protein or DNA for alignment input.\n");
NJ_usage();
exit(-1);
}
}
/* make sure that user does not specify both protein and DNA when dealing with alignment input */
if(nj_args.input_mode == NJ_INPUT_MODE_ALIGNED_SEQUENCES) {
if(nj_args.dna_flag && nj_args.protein_flag) {
fprintf(stderr, "Clearcut: Specifying protein and DNA sequences are mutually exclusive options\n");
NJ_usage();
exit(-1);
}
}
/* make sure verbose and quiet were not specified together */
if(nj_args.verbose_flag && nj_args.quiet_flag) {
fprintf(stderr, "Clearcut: Verbose and Quiet mode are mutually exclusive.\n");
NJ_usage();
exit(-1);
}
/* make sure that a correction model was specified only when providing an alignment */
if(nj_args.input_mode == NJ_INPUT_MODE_DISTANCE) {
if(nj_args.jukes_flag || nj_args.kimura_flag) {
fprintf(stderr, "Clearcut: Only specify correction model for alignment input.\n");
NJ_usage();
exit(-1);
}
} else {
if(nj_args.jukes_flag && nj_args.kimura_flag) {
fprintf(stderr, "Clearcut: Only specify one correction model\n");
NJ_usage();
exit(-1);
} else {
if(nj_args.jukes_flag && !nj_args.kimura_flag) {
nj_args.correction_model = NJ_MODEL_JUKES;
} else if(nj_args.kimura_flag && !nj_args.jukes_flag) {
nj_args.correction_model = NJ_MODEL_KIMURA;
} else {
nj_args.correction_model = NJ_MODEL_NONE; /* DEFAULT */
}
}
}
/* make sure that the number of output trees is reasonable */
if(nj_args.ntrees <= 0) {
fprintf(stderr, "Clearcut: Number of output trees must be a positive integer.\n");
NJ_usage();
exit(-1);
}
/*
* make sure that if exponential distances are specified,
* we are dealing with alignment input
*/
if(nj_args.expdist && nj_args.input_mode != NJ_INPUT_MODE_ALIGNED_SEQUENCES) {
fprintf(stderr, "Clearcut: Exponential notation for distance matrix output requires that input be an alignment\n");
NJ_usage();
exit(-1);
}
return(&nj_args);
}
/*
* NJ_print_args() -
*
*/
void
NJ_print_args(NJ_ARGS *nj_args) {
char input_mode[32];
switch (nj_args->input_mode) {
case NJ_INPUT_MODE_DISTANCE:
sprintf(input_mode, "Distance Matrix");
break;
case NJ_INPUT_MODE_UNALIGNED_SEQUENCES:
sprintf(input_mode, "Unaligned Sequences");
break;
case NJ_INPUT_MODE_ALIGNED_SEQUENCES:
sprintf(input_mode, "Aligned Sequences");
break;
default:
sprintf(input_mode, "UNKNOWN");
break;
}
printf("\n*** Command Line Arguments ***\n");
printf("Input Mode: %s\n", input_mode);
if(nj_args->stdin_flag) {
printf("Input from STDIN\n");
} else {
printf("Input File: %s\n", nj_args->infilename);
}
if(nj_args->stdout_flag) {
printf("Output from STDOUT\n");
} else {
printf("Output File: %s\n", nj_args->outfilename);
}
if(nj_args->input_mode != NJ_INPUT_MODE_DISTANCE) {
if(nj_args->aligned_flag) {
printf("Input Sequences Aligned: YES\n");
} else {
printf("Input Sequences Aligned: NO\n");
}
}
if(nj_args->verbose_flag) {
printf("Verbose Mode: ON\n");
} else {
printf("Verbose Mode: OFF\n");
}
if(nj_args->quiet_flag) {
printf("Quiet Mode: ON\n");
} else {
printf("Quiet Mode: OFF\n");
}
if(nj_args->seed) {
printf("Random Seed: %d\n", nj_args->seed);
}
printf("\n*******\n");
return;
}
/*
* NJ_usage() -
*
* Print a usage message
*
*/
void
NJ_usage(void) {
printf("Usage: clearcut --in=<infilename> --out=<outfilename> [options]...\n");
printf("GENERAL OPTIONS:\n");
printf(" -h, --help Display this information.\n");
printf(" -V, --version Print the version of this program.\n");
printf(" -v, --verbose More output. (Default: OFF)\n");
printf(" -q, --quiet Silent operation. (Default: ON)\n");
printf(" -s, --seed=<seed> Explicitly set the PRNG seed to a specific value.\n");
printf(" -r, --norandom Attempt joins deterministically. (Default: OFF)\n");
printf(" -S, --shuffle Randomly shuffle the distance matrix. (Default: OFF)\n");
printf(" -N, --neighbor Use traditional Neighbor-Joining algorithm. (Default: OFF)\n");
printf("\n");
printf("INPUT OPTIONS:\n");
printf(" -I, --stdin Read input from STDIN.\n");
printf(" -d, --distance Input file is a distance matrix. (Default: ON)\n");
printf(" -a, --alignment Input file is a set of aligned sequences. (Default: OFF)\n");
printf(" -D, --DNA Input alignment are DNA sequences.\n");
printf(" -P, --protein Input alignment are protein sequences.\n");
printf("\n");
printf("CORRECTION MODEL FOR COMPUTING DISTANCE MATRIX (Default: NO Correction):\n");
printf(" -j, --jukes Use Jukes-Cantor correction for computing distance matrix.\n");
printf(" -k, --kimura Use Kimura correction for distance matrix.\n");
printf("\n");
printf("OUTPUT OPTIONS:\n");
printf(" -O, --stdout Output tree to STDOUT.\n");
printf(" -m, --matrixout=<file> Output distance matrix to specified file.\n");
printf(" -n, --ntrees=<n> Output n trees. (Default: 1)\n");
printf(" -e, --expblen Exponential notation for branch lengths. (Default: OFF)\n");
printf(" -E, --expdist Exponential notation in distance output. (Default: OFF)\n");
printf("\n");
printf("EXAMPLES:\n");
printf(" Compute tree by supplying distance matrix via stdin:\n");
printf(" clearcut --distance < distances.txt > treefile.tre\n");
printf("\n");
printf(" Compute tree by supplying an alignment of DNA sequences from a file:\n");
printf(" clearcut --alignment --DNA --in=alignment.txt --out=treefile.tre\n");
return;
}
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