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---
name: PURPLE
url: https://github.com/hartwigmedical/hmftools/tree/master/purity-ploidy-estimator
description: A purity, ploidy and copy number estimator for whole genome tumor data
---
Purple combines B-allele frequency (BAF), read depth ratios, somatic variants and
structural variant breakpoints to estimate the purity and copy number profile
of a tumor sample, and also predicts gender, the MSI status, tumor mutational
load and burden, clonality and the whole genome duplication status.
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