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/* cddapi.c
* ===========================================================================
*
* PUBLIC DOMAIN NOTICE
* National Center for Biotechnology Information (NCBI)
*
* This software/database is a "United States Government Work" under the
* terms of the United States Copyright Act. It was written as part of
* the author's official duties as a United States Government employee and
* thus cannot be copyrighted. This software/database is freely available
* to the public for use. The National Library of Medicine and the U.S.
* Government do not place any restriction on its use or reproduction.
* We would, however, appreciate having the NCBI and the author cited in
* any work or product based on this material
*
* Although all reasonable efforts have been taken to ensure the accuracy
* and reliability of the software and data, the NLM and the U.S.
* Government do not and cannot warrant the performance or results that
* may be obtained by using this software or data. The NLM and the U.S.
* Government disclaim all warranties, express or implied, including
* warranties of performance, merchantability or fitness for any particular
* purpose.
*
* ===========================================================================
*
* File Name: cddapi.c
*
* Author: Jonathan Kans
*
* Version Creation Date: 8/16/00
*
* $Revision: 1.13 $
*
* File Description:
*
* Modifications:
* --------------------------------------------------------------------------
* Date Name Description of modification
* ------- ---------- -----------------------------------------------------
*
*
* ==========================================================================
*/
#include <ncbi.h>
#include <urlquery.h>
#include <cddapi.h>
#include <seqport.h>
#include <sqnutils.h>
/* low-level connection functions */
NLM_EXTERN CONN CddOpenConnection (
BioseqPtr bsp,
FloatHi expectValue,
Boolean findBest,
Boolean doFilter,
Boolean makeFeats,
CharPtr dataLib,
Boolean precalc
)
{
CONN conn;
Char expect [32];
Char feats [16];
Char filter [8];
Char graph [8];
Char id [42];
Char inputtype [32];
size_t len;
CharPtr query;
SeqIdPtr sip;
CharPtr str;
/*
size_t n_written;
EIO_Status status;
*/
if (bsp == NULL) return NULL;
if (! ISA_aa (bsp->mol)) return NULL;
str = GetSequenceByBsp (bsp);
if (StringHasNoText (str)) return NULL;
len = StringLen (str);
query = (CharPtr) MemNew (len + 128);
if (query == NULL) {
MemFree (str);
return NULL;
}
sprintf (expect, "%7.4lf", (double) expectValue);
TrimSpacesAroundString (expect);
if (findBest) {
StringCpy (graph, "1");
} else {
StringCpy (graph, "2");
}
if (doFilter) {
StringCpy (filter, "T");
} else {
StringCpy (filter, "F");
}
if (makeFeats) {
StringCpy (feats, "AONLY");
} else {
StringCpy (feats, "LONLY");
}
if (StringHasNoText (dataLib)) {
dataLib = "cdd";
}
if (precalc) {
StringCpy (inputtype, "INPUT_TYPE=precalc&FULL&");
} else {
StringCpy (inputtype, "");
}
sip = SeqIdFindBest (bsp->id, 0);
if (precalc) {
SeqIdWrite (sip, id, PRINTID_REPORT, sizeof (id) - 1);
} else {
SeqIdWrite (sip, id, PRINTID_FASTA_SHORT, sizeof (id) - 1);
}
if (StringHasNoText (id)) {
StringCpy (id, "tmpseq_0");
}
/*
sprintf (query, "%s&NOHTML&DATALIB=%s&EXPECT=%s&FILTER=%s&GRAPH=%s&SEQUENCE=>%s%s%s",
feats, dataLib, expect, filter, graph, id, "%0A", str);
conn = QUERY_OpenUrlQuery ("www.ncbi.nlm.nih.gov", 80, "/Structure/cdd/wrpsb.cgi",
NULL, "Entrez2Tool", 30, eMIME_T_NcbiData,
eMIME_Plain, eENCOD_None, 0);
status = CONN_Write (conn, (const void *) query, StringLen (query), &n_written, eIO_WritePersist);
if (status != eIO_Success) {
CONN_Close (conn);
MemFree (str);
MemFree (query);
return NULL;
}
*/
if (precalc) {
sprintf (query, "%s&NOHTML&DATALIB=%s&EXPECT=%s&FILTER=%s&GRAPH=%s&%sSEQUENCE=%s",
feats, dataLib, expect, filter, graph, inputtype, id);
} else {
sprintf (query, "%s&NOHTML&DATALIB=%s&EXPECT=%s&FILTER=%s&GRAPH=%s&%sSEQUENCE=>%s%s%s",
feats, dataLib, expect, filter, graph, inputtype, id, "%0A", str);
}
conn = QUERY_OpenServiceQuery ("CddSearch2", query, 30);
MemFree (str);
MemFree (query);
return conn;
}
NLM_EXTERN SeqAnnotPtr CddReadReply (
CONN conn,
EIO_Status status
)
{
AsnIoConnPtr aicp;
SeqAnnotPtr sap = NULL;
if (conn != NULL && status == eIO_Success) {
aicp = QUERY_AsnIoConnOpen ("r", conn);
if (aicp == NULL || aicp->aip == NULL) return NULL;
/*
aicp->aip->scan_for_start = TRUE;
*/
sap = SeqAnnotAsnRead (aicp->aip, NULL);
QUERY_AsnIoConnClose (aicp);
if (sap != NULL && sap->data == NULL) {
sap = SeqAnnotFree (sap);
}
}
return sap;
}
#ifdef OS_MAC
#include <Events.h>
#endif
NLM_EXTERN SeqAnnotPtr CddWaitForReply (
CONN conn
)
{
time_t currtime, starttime;
time_t max = 0;
SeqAnnotPtr sap = NULL;
EIO_Status status;
STimeout timeout;
#ifdef OS_MAC
EventRecord currEvent;
#endif
if (conn == NULL) return NULL;
#ifdef OS_MAC
timeout.sec = 0;
timeout.usec = 0;
#else
timeout.sec = 100;
timeout.usec = 0;
#endif
starttime = GetSecs ();
while ((status = CONN_Wait (conn, eIO_Read, &timeout)) == eIO_Timeout && max < 300) {
currtime = GetSecs ();
max = currtime - starttime;
#ifdef OS_MAC
WaitNextEvent (0, &currEvent, 0, NULL);
#endif
}
if (status == eIO_Success) {
sap = CddReadReply (conn, status);
}
CONN_Close (conn);
return sap;
}
/* high-level connection functions */
NLM_EXTERN SeqAnnotPtr CddSynchronousQuery (
BioseqPtr bsp,
FloatHi expectValue,
Boolean findBest,
Boolean doFilter,
Boolean makeFeats,
CharPtr dataLib,
Boolean precalc
)
{
CONN conn;
SeqAnnotPtr sap;
conn = CddOpenConnection (bsp, expectValue, findBest, doFilter, makeFeats, dataLib, precalc);
if (conn == NULL) return NULL;
QUERY_SendQuery (conn);
sap = CddWaitForReply (conn);
return sap;
}
NLM_EXTERN Boolean CddAsynchronousQuery (
BioseqPtr bsp,
FloatHi expectValue,
Boolean findBest,
Boolean doFilter,
Boolean makeFeats,
CharPtr dataLib,
Boolean precalc,
QUEUE* queue,
QueryResultProc resultproc,
VoidPtr userdata
)
{
CONN conn;
conn = CddOpenConnection (bsp, expectValue, findBest, doFilter, makeFeats, dataLib, precalc);
if (conn == NULL) return FALSE;
QUERY_SendQuery (conn);
QUERY_AddToQueue (queue, conn, resultproc, userdata, TRUE);
return TRUE;
}
NLM_EXTERN Int4 CddCheckQueue (
QUEUE* queue
)
{
return QUERY_CheckQueue (queue);
}
/* utility functions */
static void PromoteSeqId (SeqIdPtr sip, Pointer userdata)
{
SeqIdPtr bestid, newid, oldid;
if (sip == NULL) return;
/* change lcl|tmpseq_0 returned from CGI, or gi if precalcualted */
if (sip->choice != SEQID_LOCAL && sip->choice != SEQID_GI) return;
bestid = (SeqIdPtr) userdata;
newid = SeqIdDup (bestid);
if (newid == NULL) return;
oldid = ValNodeNew (NULL);
if (oldid == NULL) return;
MemCopy (oldid, sip, sizeof (ValNode));
oldid->next = NULL;
sip->choice = newid->choice;
sip->data.ptrvalue = newid->data.ptrvalue;
SeqIdFree (oldid);
ValNodeFree (newid);
SeqIdStripLocus (sip);
}
static void CorrectFeatureSeqIds (
SeqFeatPtr sfp,
Pointer userdata
)
{
VisitSeqIdsInSeqLoc (sfp->location, userdata, PromoteSeqId);
}
static void CorrectAlignmentSeqIds (
SeqAlignPtr sap,
Pointer userdata
)
{
VisitSeqIdsInSeqAlign (sap, userdata, PromoteSeqId);
}
NLM_EXTERN void CddCorrectIDs (
BioseqPtr bsp,
SeqAnnotPtr sap
)
{
SeqEntryPtr scope;
SeqIdPtr sip;
if (bsp == NULL || sap == NULL) return;
sip = SeqIdFindBest (bsp->id, 0);
scope = SeqEntrySetScope (NULL);
VisitFeaturesOnSap (sap, (Pointer) sip, CorrectFeatureSeqIds);
VisitAlignmentsOnSap (sap, (Pointer) sip, CorrectAlignmentSeqIds);
SeqEntrySetScope (scope);
}
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