1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 54 55 56 57 58 59 60 61 62 63 64 65 66 67 68 69 70 71 72 73 74 75 76 77 78 79 80 81 82 83 84 85 86 87 88 89 90 91 92 93 94 95 96 97 98 99 100 101 102 103 104 105 106 107 108 109 110 111 112 113 114 115 116 117 118 119 120 121 122 123 124 125 126 127 128 129 130 131 132 133 134 135 136 137 138 139 140 141 142 143 144 145 146 147 148 149 150 151 152 153 154 155 156 157 158 159 160 161 162 163 164 165 166 167 168 169 170 171 172 173 174 175 176 177 178 179 180 181 182 183 184 185 186 187 188 189 190 191 192 193 194 195 196 197 198 199 200 201 202 203 204 205 206 207 208 209 210 211 212 213 214 215 216 217 218 219 220 221 222 223 224 225 226 227 228 229 230 231 232 233 234 235 236 237 238 239 240 241 242 243 244 245 246 247 248 249 250 251 252 253 254 255 256 257 258 259 260 261 262 263 264 265 266 267 268 269 270 271 272 273 274 275 276 277 278 279 280 281 282 283 284 285 286 287 288 289 290 291 292 293 294 295 296 297 298 299 300 301 302 303 304 305 306 307 308 309 310 311 312 313 314 315 316 317 318 319 320 321 322 323 324 325 326 327 328 329 330 331 332 333 334 335 336 337 338 339 340 341 342 343 344 345 346 347 348 349 350 351 352 353 354 355 356 357 358 359 360 361 362 363 364 365 366 367 368 369 370 371 372 373 374 375 376 377 378 379 380 381 382 383 384 385 386 387 388 389 390 391 392 393 394 395 396 397 398 399 400 401 402 403 404 405 406 407 408 409 410 411 412 413 414
|
#include <odinseq/seqall.h>
class METHOD_CLASS : public SeqMethod {
private:
SeqPulsar exc;
SeqPulsarReph exc_reph;
SeqPulsar refoc;
SeqAcqRead acqread;
SeqAcqRead acqread_templ;
SeqAcqDeph readdeph;
SeqGradPhaseEnc pe1,pe2;
SeqGradPhaseEnc pe3d1,pe3d2;
SeqGradConstPulse spoiler;
SeqGradConstPulse crusher;
SeqDelay echopad;
SeqDelay excpad;
SeqDelay relaxdelay;
SeqObjList echopart;
SeqObjList echopart_templ;
SeqGradTrapezParallel postexc;
SeqObjList scan;
SeqObjList readout;
SeqObjList readout_templ;
SeqObjList pe1part;
SeqObjList pe2part;
SeqDelay pe1delay;
SeqDelay pe2delay;
SeqObjLoop echoloop;
SeqObjLoop segloop;
SeqObjLoop sliceloop;
SeqObjLoop reploop;
SeqObjLoop loop3d;
SeqVector echoindex; // index vector for echoes
LDRenum PhaseEncoding;
LDRint NumOfSegments;
LDRdouble PulseDur;
LDRdouble refocFlipAngle;
LDRdouble SpoilerStrength;
LDRbool TemplScan;
LDRdouble RefocRate;
public:
METHOD_CLASS(const STD_string& label) : SeqMethod(label) {
set_description("Segmented 2D/3D RARE (Turbo SE) Sequence. "
"Phase correction is possible by using a prescan with phase-encoding gradients switched off. ");
}
unsigned int numof_testcases() const {return 3;}
void method_pars_init() {
PhaseEncoding.add_item("Linear",linearEncoding);
PhaseEncoding.add_item("Reverse",reverseEncoding);
PhaseEncoding.add_item("CenterOut",centerOutEncoding);
PhaseEncoding.add_item("CenterIn",centerInEncoding);
PhaseEncoding=centerOutEncoding;
PhaseEncoding.set_description("Phase encoding order");
NumOfSegments=4;
NumOfSegments.set_description("Number of excitation to acquire one slice/partition");
PulseDur=5.0;
PulseDur.set_unit(ODIN_TIME_UNIT).set_description("Duration of excitation and refocusing pulse");
refocFlipAngle=180.0;
refocFlipAngle.set_unit(ODIN_ANGLE_UNIT).set_description("Refocusing flip angle");
SpoilerStrength=50.0;
SpoilerStrength.set_unit("%").set_description("Spoiler-gradient strength in percent of max gradient amplitude");
TemplScan=true;
TemplScan.set_description("Acquire and use template scan for phase correction");
RefocRate.set_unit(ODIN_TIME_UNIT).set_description("Spacing between refocusing pulses");
// alternative default settings for sequence test
if(get_current_testcase()==1) {
geometryInfo->set_Mode(voxel_3d);
PhaseEncoding=linearEncoding;
commonPars->set_PartialFourier(0.8);
PulseDur=6.0;
refocFlipAngle=120.0;
SpoilerStrength=30.0;
}
if(get_current_testcase()==2) {
commonPars->set_ReductionFactor(3);
TemplScan=false;
NumOfSegments=1;
}
append_parameter(PhaseEncoding,"PhaseEncoding");
append_parameter(NumOfSegments,"NumOfSegments");
append_parameter(PulseDur,"PulseDur");
append_parameter(TemplScan,"TemplScan");
append_parameter(refocFlipAngle,"refocFlipAngle");
append_parameter(SpoilerStrength,"SpoilerStrength");
append_parameter(RefocRate,"RefocRate",noedit);
}
/////////////////////////////////////////////////////////////////////////////////////////////////
void method_seq_init(){
Log<Seq> odinlog(this,"method_seq_init");
float gamma=systemInfo->get_gamma("");
///////////////// Pulses: /////////////////////
float slicethick=geometryInfo->get_sliceThickness();
if(geometryInfo->get_Mode()==voxel_3d) {
slicethick=geometryInfo->get_FOV(sliceDirection);
}
float spatres=slicethick/4.0;
// Excitation Pulse
exc=SeqPulsarSinc("exc",slicethick,false,PulseDur,commonPars->get_FlipAngle(),spatres,256);
if(geometryInfo->get_Mode()==slicepack) exc.set_freqlist (gamma * exc.get_strength() / (2.0*PII) * geometryInfo->get_sliceOffsetVector() );
if(geometryInfo->get_Mode()==voxel_3d) exc.set_freqoffset(gamma * exc.get_strength() / (2.0*PII) * geometryInfo->get_offset(sliceDirection) );
exc.set_pulse_type(excitation);
// rephasing lobe for excitation pulse
exc_reph=SeqPulsarReph("exc_reph",exc);
// Refocusing Pulse
refoc=SeqPulsarSinc("refoc",slicethick,false,PulseDur,refocFlipAngle,spatres,256);
if(geometryInfo->get_Mode()==slicepack) refoc.set_freqlist (gamma * refoc.get_strength() / (2.0*PII) * geometryInfo->get_sliceOffsetVector() );
if(geometryInfo->get_Mode()==voxel_3d) refoc.set_freqoffset(gamma * refoc.get_strength() / (2.0*PII) * geometryInfo->get_offset(sliceDirection) );
refoc.set_phase(90.0);
refoc.set_pulse_type(refocusing);
////////////////// Geometry: /////////////////////////////////
// calculate the resolution in the read Channel and set the number of phase encoding
// steps so that we will obtain a uniform resolution in read and phase Channel:
float resolution=secureDivision(geometryInfo->get_FOV(readDirection),commonPars->get_MatrixSize(readDirection));
commonPars->set_MatrixSize(phaseDirection,int(secureDivision(geometryInfo->get_FOV(phaseDirection),resolution)+0.5),noedit);
commonPars->set_MatrixSize(sliceDirection,int(secureDivision(geometryInfo->get_FOV(sliceDirection),resolution)+0.5),noedit);
//////////////// Phase Encoding: //////////////////////////
pe1=SeqGradPhaseEnc("pe1",commonPars->get_MatrixSize(phaseDirection),geometryInfo->get_FOV(phaseDirection),
phaseDirection,0.25*systemInfo->get_max_grad(),
encodingScheme(int(PhaseEncoding)),interleavedSegmented,NumOfSegments,
commonPars->get_ReductionFactor(), DEFAULT_ACL_BANDS, commonPars->get_PartialFourier());
pe2=pe1;
pe2.set_label("pe2");
pe2.invert_strength();
// Echo indices for template correction
unsigned int nechoes=((const SeqVector&)pe1).get_numof_iterations();
ODINLOG(odinlog,significantDebug) << "nechoes=" << nechoes << STD_endl;
echoindex=SeqVector("echoindex",nechoes);
//////////////// Phase Encoding (3D): //////////////////////////
if(geometryInfo->get_Mode()==voxel_3d) {
pe3d1=SeqGradPhaseEnc("pe3d1",commonPars->get_MatrixSize(sliceDirection),geometryInfo->get_FOV(sliceDirection),pe1.get_constduration(),
sliceDirection, linearEncoding, noReorder, 1, commonPars->get_ReductionFactor());
pe3d2=pe3d1;
pe3d2.set_label("pe3d2");
pe3d2.invert_strength();
}
//////////////// Readout: //////////////////////////////
acqread=SeqAcqRead("acqread",commonPars->get_AcqSweepWidth(),commonPars->get_MatrixSize(readDirection),
geometryInfo->get_FOV(readDirection),readDirection);
acqread_templ=SeqAcqRead(acqread);
acqread_templ.set_label("acqread_templ");
acqread_templ.set_template_type(phasecorr_template);
readdeph=SeqAcqDeph("readdeph",acqread,spinEcho);
//////////////// Spoiler/Crusher: //////////////////////////////
float spoiler_strength=(double)SpoilerStrength/100.0*systemInfo->get_max_grad();
float spoiler_integral=2.5*fabs(readdeph.get_gradintegral().sum());
float spoiler_dur=secureDivision(spoiler_integral,spoiler_strength);
spoiler=SeqGradConstPulse("spoiler",phaseDirection,spoiler_strength,spoiler_dur);
crusher=SeqGradConstPulse("crusher",readDirection,spoiler_strength,2.0*spoiler_dur);
//////////////// several padding delays ////////////////////
excpad=SeqDelay("excpad");
echopad=SeqDelay("echopad");
relaxdelay=SeqDelay("relaxdelay");
pe1delay=SeqDelay("pe1delay");
pe2delay=SeqDelay("pe2delay");
//////////////// total sequence: //////////////////////////////
echopart=SeqObjList("echopart");
echopart_templ=SeqObjList("echopart_templ");
scan=SeqObjList("scan");
echoloop=SeqObjLoop("echoloop");
segloop=SeqObjLoop("segloop");
sliceloop=SeqObjLoop("sliceloop");
reploop=SeqObjLoop("reploop");
loop3d=SeqObjLoop("loop3d");
readout=SeqObjList("readout");
fvector gradint(3); gradint=0.0;
gradint+=exc_reph.get_gradintegral();
gradint+=readdeph.get_gradintegral();
gradint+=spoiler.get_gradintegral();
postexc=SeqGradTrapezParallel("postexc",gradint[0],gradint[1],gradint[2],0.5*systemInfo->get_max_grad());
ODINLOG(odinlog,significantDebug) << "postexc. get_gradintegral()=" << postexc.get_gradintegral().printbody() << STD_endl;
float spoiler_k_diff=systemInfo->get_gamma()*(spoiler.get_gradintegral()[1]-postexc.get_gradintegral()[1]);
ODINLOG(odinlog,significantDebug) << "spoiler_k_diff=" << spoiler_k_diff << STD_endl;
if(geometryInfo->get_Mode()==voxel_3d) {
pe1part+=pe1/pe3d1;
pe2part+=pe2/pe3d2;
} else {
pe1part+=pe1;
pe2part+=pe2;
}
pe1delay=SeqDelay("pe1delay",pe1part.get_duration());
pe2delay=SeqDelay("pe2delay",pe2part.get_duration());
echopart_templ= refoc + spoiler + echopad + pe1delay + acqread_templ + pe2delay + echopad + spoiler;
echopart = refoc + spoiler + echopad + pe1part + acqread + pe2part + echopad + spoiler;
readout_templ = exc + postexc + excpad + echoloop(echopart_templ)[echoindex] + crusher;
readout = exc + postexc + excpad + echoloop(echopart) [pe1][pe2][echoindex] + crusher;
if(geometryInfo->get_Mode()==voxel_3d) {
if(TemplScan) {
scan+= readout_templ + relaxdelay;
}
scan+= reploop(
segloop(
loop3d(
readout + relaxdelay
)[pe3d1][pe3d2]
)[pe1.get_reorder_vector()][pe2.get_reorder_vector()]
)[commonPars->get_NumOfRepetitions()];
} else {
if(TemplScan) {
scan+= sliceloop(
readout_templ + relaxdelay
)[exc][refoc];
}
scan+= reploop(
segloop(
sliceloop(
readout + relaxdelay
)[exc][refoc]
)[pe1.get_reorder_vector()][pe2.get_reorder_vector()]
)[commonPars->get_NumOfRepetitions()];
}
set_sequence( scan );
}
/////////////////////////////////////////////////////////////////////////////////////////////////
void method_rels(){
Log<Seq> odinlog(this,"method_rels");
// CPMG timings
double TE1=exc.get_duration()-exc.get_magnetic_center()+
postexc.get_duration()+
refoc.get_magnetic_center();
double TE2=(echopart.get_duration())/2.;
ODINLOG(odinlog,significantDebug) << "TE1/TE2=" << TE1 << "/" << TE2 << STD_endl;
if(TE2-TE1 < 0) echopad.set_duration(echopad.get_duration()-(TE2-TE1));
else excpad.set_duration(excpad.get_duration()+(TE2-TE1));
ODINLOG(odinlog,significantDebug) << "echopad=" << echopad.get_duration() << STD_endl;
ODINLOG(odinlog,significantDebug) << "excpad=" << excpad.get_duration() << STD_endl;
RefocRate=echopart.get_duration();
// Find echo with minimum phase encoding for TE calculation
iarray indexmat=((SeqVector)pe1).get_index_matrix();
ODINLOG(odinlog,significantDebug) << "indexmat=" << indexmat << STD_endl;
fvector trims=pe1.get_trims();
ODINLOG(odinlog,significantDebug) << "trims=" << trims << STD_endl;
float mintrim=-1.0;
unsigned int minreorder=0;
unsigned int miniter=0;
for(unsigned int ireorder=0; ireorder<indexmat.size(0); ireorder++) {
for(unsigned int iter=0; iter<indexmat.size(1); iter++) {
unsigned int itrim=indexmat(ireorder,iter);
float trimabsval=fabs(trims[itrim]);
bool ismin=false;
if(!ireorder && !iter) { // 1st value
ismin=true;
} else {
if(trimabsval<mintrim) ismin=true;
}
if(ismin) {
mintrim=trimabsval;
minreorder=ireorder;
miniter=iter;
}
ODINLOG(odinlog,significantDebug) << "(ireorder/iter/itrim) trimabsval=" << "(" << ireorder << "/" << iter << "/" << itrim<< ") " << trimabsval << STD_endl;
}
}
ODINLOG(odinlog,significantDebug) << "minreorder/miniter/mintrim=" << minreorder << "/" << miniter << "/" << mintrim << STD_endl;
commonPars->set_EchoTime((miniter+1)*RefocRate,noedit);
// calculate relaxdelay to get the desired repetition time
float scandur=readout.get_duration()*float(geometryInfo->get_nSlices());
if(scandur>commonPars->get_RepetitionTime()) commonPars->set_RepetitionTime(scandur);
relaxdelay=(commonPars->get_RepetitionTime()-scandur)/float(geometryInfo->get_nSlices());
}
/////////////////////////////////////////////////////////////////////////////////////////////////
void method_pars_set(){
// inform the readout about the used phase encoding and slice vector (for automatic reconstruction)
acqread.set_reco_vector(line,pe1);
acqread_templ.set_reco_vector(echo,echoindex);
acqread.set_reco_vector(echo,echoindex);
if(geometryInfo->get_Mode()==voxel_3d) {
acqread.set_reco_vector(line3d,pe3d1);
}
acqread.set_reco_vector(slice,exc);
acqread_templ.set_reco_vector(slice,exc);
}
};
/////////////////////////////////////////////////////////////////////////////////////////////////
// entry point for the sequence module
ODINMETHOD_ENTRY_POINT
|