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<TITLE>Consensus peptide identification</TITLE>
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<div class="title">Consensus peptide identification </div> </div>
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<div class="textblock"><p><b>Goal:</b> Use several identification engines in order to compute a consensus identification for a HPLC-MS\MS experiment.</p>
<p>OpenMS offers adapters for the following commercial and free peptide identification engines: Sequest, Mascot, OMSSA, PepNovo, XTandem and Inspect.<br/>
The adapters allow setting the input parameters and data for the identification engine and return the result in the OpenMS idXML format.</p>
<p>In order to improve the identification accuracy, several identification engines can be used and a consensus identification can be calculated from the results. The image below shows an example where Mascot and OMSSA results are fed to the <b>ConsensusID</b> tool (ConsensusID is currently usable for Mascot, OMSSA and XTandem).</p>
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<img src="TOPP_consensus_id.png" alt="TOPP_consensus_id.png"/>
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<p><b>Goal:</b> Combine quantitation and identification results.</p>
<p>Protein/peptide identifications can be annotated to quantitation results (featureXML, conensusXML) by the <b>IDMapper</b> tool. The combined results can then be exported by the <b>TextExporter</b> tool: <a class="el" href="TOPP_example_convert.html">Conversion between OpenMS XML formats and text formats</a> . </p>
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<TD><font color="#c0c0c0">OpenMS / TOPP release 1.11.1</font></TD>
<TD align="right"><font color="#c0c0c0">Documentation generated on Thu Nov 14 2013 11:19:25 using doxygen 1.8.5</font></TD>
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