1
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5
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11
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13
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17
18
19
20
21
22
23
24
25
26
27
28
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31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
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59
60
61
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63
64
65
66
67
68
69
70
71
72
73
74
75
76
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78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
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162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
|
Last position-specific scoring matrix computed, weighted observed percentages rounded down, information per position, and relative weight of gapless real matches to pseudocounts
A R N D C Q E G H I L K M F P S T W Y V A R N D C Q E G H I L K M F P S T W Y V
1 M -1 -1 -2 -3 -2 0 -2 -3 -2 1 2 -1 6 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.33 0.00
2 G 0 -3 0 -1 -3 -2 -2 6 -2 -4 -4 -2 -3 -3 -2 0 -2 -3 -3 -3 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.04 0.00
3 E -1 0 0 2 -4 2 5 -2 0 -3 -3 1 -2 -3 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.00
4 L -2 -2 -4 -4 -1 -2 -3 -4 -3 2 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.45 0.00
5 P -1 -2 -2 -2 -3 -1 -1 -2 -2 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.04 0.00
6 N 0 -1 5 1 -2 0 0 -1 0 -3 -3 0 -2 -3 -2 3 1 -4 -2 -3 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0.55 0.06
7 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
8 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
9 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
10 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
11 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
12 A 3 -2 -1 -2 -1 -1 -1 -1 -2 -1 -2 -1 -1 -3 -1 1 3 -3 -2 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0.37 0.06
13 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
14 T -1 -1 4 0 -2 -1 -1 -1 -1 -2 -2 -1 -1 -3 -2 1 4 -3 -2 -1 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0.47 0.06
15 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0.43 0.06
16 A 3 -2 -1 -2 -1 -1 -2 4 -2 -2 -3 -1 -2 -3 -2 0 -1 -3 -3 -1 59 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0.52 0.06
17 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
18 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
19 V 0 -2 -2 -2 -1 -2 -2 -3 -3 2 0 -2 0 -2 -2 0 3 -3 -2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 59 0.31 0.06
20 S 0 -2 0 -1 -2 -1 -1 -1 -2 -3 -3 -1 -2 -3 6 3 0 -4 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 59 0 0 0 0 0.82 0.06
21 A 3 -2 -2 -3 -1 -1 -2 -1 0 -2 -2 -1 -1 1 -2 0 -1 0 5 -1 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0.39 0.06
22 Y -2 -2 -3 -4 -3 -2 -3 -3 1 -1 -1 -3 -1 5 -4 -2 -2 2 6 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 59 0 0.80 0.06
23 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
24 D 0 -2 1 5 -2 0 1 -1 -1 -3 -3 -1 -3 -3 -1 3 0 -4 -3 -3 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0.60 0.06
25 N -2 -1 5 4 -3 0 0 -1 0 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06
26 S 0 4 0 -1 -2 0 0 -1 -1 -3 -3 1 -2 -3 -2 3 0 -3 -2 -2 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0.44 0.06
27 G -1 -2 0 4 -3 -1 0 5 -2 -4 -4 -1 -3 -4 -2 0 -2 -4 -3 -4 0 0 0 41 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
28 S 0 -1 4 0 -2 0 0 -1 0 -3 -3 0 -2 -3 -2 3 1 -4 -2 -2 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0.49 0.06
29 E -1 0 0 1 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.06
30 L -2 -3 -4 -4 -2 -2 -3 -4 -3 0 3 -3 1 1 -4 -3 -2 9 1 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 41 0 0 0.94 0.06
31 S 1 -1 0 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.53 0.06
32 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.56 0.06
33 P -1 -2 -2 -2 -3 -2 -1 -2 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.11 0.06
34 N -2 -1 5 0 -3 0 0 -1 6 -4 -4 -1 -2 -2 -2 0 -1 -3 0 -3 0 0 59 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0.67 0.06
35 F -2 -3 -4 -4 -2 -3 -4 -4 -2 3 1 -3 0 5 -4 -3 -2 0 2 1 0 0 0 0 0 0 0 0 0 41 0 0 0 59 0 0 0 0 0 0 0.50 0.06
36 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.56 0.06
37 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0.43 0.06
38 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
39 F -3 -3 -4 -4 -3 -3 -3 -3 -2 -1 0 -3 -1 6 -4 -3 -3 9 3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 41 0 0 1.19 0.06
40 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
41 K -1 1 -1 -2 -3 0 0 -2 0 -2 -2 4 -1 1 -2 -1 -1 0 5 -2 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 41 0 0.45 0.06
42 N -2 -1 5 0 -3 0 0 -1 6 -4 -4 -1 -2 -2 -2 0 -1 -3 0 -3 0 0 59 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0.67 0.06
43 F -1 -3 -3 -4 -2 -3 -3 -4 -2 1 0 -3 0 5 -3 -2 -1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 41 0.47 0.06
44 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
45 E -1 0 0 1 -4 4 5 -2 0 -3 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 41 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0.68 0.06
46 H -2 -1 0 -2 -3 0 -1 -3 7 -3 -2 -1 -2 1 -3 -1 -2 0 5 -3 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0 0.77 0.06
47 V -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -3 -1 3 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 59 0.37 0.06
48 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
49 V -1 -3 -3 -4 -2 -3 -3 -4 -3 2 1 -3 0 4 -3 -2 -1 -1 1 3 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 59 0.39 0.06
50 E -1 0 0 1 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.06
51 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
52 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 41 0.39 0.06
53 F -2 -3 -4 -4 -2 -3 -3 -4 -2 1 3 -3 1 5 -4 -3 -2 0 2 0 0 0 0 0 0 0 0 0 0 0 41 0 0 59 0 0 0 0 0 0 0.54 0.06
54 R -2 6 -1 -2 -4 1 0 -3 0 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.06
55 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
56 T 0 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 3 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 59 0 0 0 0.45 0.06
57 Q -1 1 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
58 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
59 E -1 0 0 1 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.06
60 V -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -3 -1 3 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 59 0.37 0.06
61 T -1 1 0 -1 -2 0 0 -2 -2 -2 -2 3 -1 -3 -1 1 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 59 0 0 0 0.38 0.06
62 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
63 S 0 -1 1 4 -2 0 1 -1 -1 -3 -3 -1 -2 -3 -1 3 0 -4 -3 -3 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0.51 0.06
64 T -1 1 0 -1 -2 0 0 -2 -2 -2 -2 3 -1 -3 -1 1 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 59 0 0 0 0.38 0.06
65 T 2 -2 -2 -2 -1 -2 -2 -2 -2 0 2 -2 1 -1 -2 0 2 -2 -2 0 29 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 29 0 0 0 0.21 0.06
66 G 0 0 -1 -1 -3 0 -1 5 -2 -4 -4 3 -2 -4 -2 0 -1 -3 -3 -3 0 0 0 0 0 0 0 59 0 0 0 41 0 0 0 0 0 0 0 0 0.61 0.06
67 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.56 0.06
68 S 0 -1 1 4 -2 0 1 -1 -1 -3 -3 -1 -2 -3 -1 3 0 -4 -3 -3 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0.51 0.06
69 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
70 N -2 -1 5 4 -3 0 0 -1 0 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06
71 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
72 D -2 -1 1 5 -4 0 1 -2 6 -4 -4 -1 -3 -3 -2 -1 -2 -4 0 -4 0 0 0 59 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06
73 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
74 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
75 Q -1 1 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
76 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
77 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
78 V -1 -2 -3 -4 -1 -2 -3 -3 -3 2 1 -2 5 -1 -3 -2 0 -3 -1 3 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 59 0.34 0.06
79 S 1 -1 0 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.53 0.06
80 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
81 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 41 0.39 0.06
82 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
83 S 1 -1 0 -1 -1 -1 -1 -1 -1 -2 -2 -1 -1 -3 -1 4 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0.44 0.06
84 T 0 -1 0 -1 -1 -1 -1 -1 -2 -2 -2 -1 -1 -3 -1 3 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 59 0 0 0 0.45 0.06
85 G -1 -2 0 4 -3 -1 0 5 -2 -4 -4 -1 -3 -4 -2 0 -2 -4 -3 -4 0 0 0 41 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
86 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
87 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
88 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
89 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
90 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.56 0.06
91 P -1 -2 -2 -2 -3 -2 -1 -2 -3 -3 -3 -1 -3 -4 8 -1 -1 -4 -3 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 2.11 0.06
92 I -2 -3 -4 -4 -2 -3 -3 -4 -3 4 3 -3 1 0 -3 -3 -1 -3 -1 2 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.43 0.06
93 S 1 -1 0 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.53 0.06
94 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
95 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
96 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
97 R -2 6 -1 -2 -4 1 0 -3 0 -3 -3 2 -2 -3 -2 -1 -1 -3 -2 -3 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.85 0.06
98 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 41 0.39 0.06
99 S 1 -1 0 -1 -1 -1 -1 -1 -1 -2 -2 -1 -1 -3 -1 4 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0.44 0.06
100 G 3 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -1 -2 -3 -2 0 -1 -3 -3 -2 41 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.06
101 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
102 I -1 -3 -2 -3 -2 -3 -3 4 -3 3 0 -2 0 -1 -3 -2 -1 -3 -2 1 0 0 0 0 0 0 0 41 0 59 0 0 0 0 0 0 0 0 0 0 0.35 0.06
103 T 0 -1 0 -1 -1 -1 -1 -2 -2 -1 -1 -1 -1 -2 -1 1 5 -3 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0.56 0.06
104 Q -1 1 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
105 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
106 N -2 0 5 1 -3 1 3 -1 0 -4 -4 0 -2 -4 -2 0 -1 -4 -2 -3 0 0 59 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0.61 0.06
107 M -1 -2 -3 -3 -2 -1 -2 -3 -2 1 2 -2 7 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.47 0.06
108 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
109 D -1 -1 1 5 -2 0 1 -1 -1 -2 -2 0 -2 -2 -1 0 -1 -2 -2 -2 3 2 2 61 1 2 3 3 1 2 4 2 1 2 2 3 2 1 1 3 0.43 0.03
110 V 0 -1 -1 -2 -1 -1 -1 -2 -2 2 0 -1 0 -1 -1 -1 0 -1 -1 3 3 2 2 2 1 2 3 3 1 2 4 2 1 2 2 3 2 1 1 61 0.14 0.03
111 T 0 -2 -1 -2 -1 -1 -2 -2 -3 1 0 -2 0 -2 -2 0 4 -3 -2 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 41 0.33 0.06
112 N -1 -1 5 0 -3 -1 -1 -1 0 -3 -4 -1 -3 -4 5 0 -1 -4 -3 -3 0 0 59 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0.93 0.06
113 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
114 A 3 0 -1 -1 -1 4 0 -1 -1 -2 -2 0 -1 -3 -1 1 0 -3 -2 -1 59 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.38 0.06
115 V -1 -1 -2 -2 -2 4 0 -3 -1 1 0 0 0 -2 -2 -1 0 -3 -2 3 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0.27 0.06
116 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.61 0.06
117 I -1 -3 -4 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 41 0.43 0.06
118 S 1 -1 0 -1 -1 -1 -1 -1 -1 -2 -2 -1 -1 -3 -1 4 4 -3 -2 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0.44 0.06
119 E -1 -1 0 5 -4 1 4 -2 -1 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 41 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.06
120 E -1 -1 0 5 -4 1 4 -2 -1 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 41 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0.74 0.06
121 A 4 -1 -1 -1 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 3 1 -3 -2 -1 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0.40 0.06
122 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
123 M 2 -2 -2 -3 -1 -1 -2 -1 -2 0 1 -1 5 -1 -2 0 -1 -2 -2 0 41 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0.28 0.06
124 I -2 -3 -4 -4 -2 -3 -3 -4 -3 4 3 -3 1 0 -3 -3 -1 -3 -1 2 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.43 0.06
125 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
126 N -2 -1 6 1 -3 0 0 -1 0 -4 -4 0 -3 -3 -2 0 0 -4 -2 -3 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.83 0.06
127 V -1 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 59 0.42 0.06
128 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
129 G 3 -2 -1 -2 -2 -2 -2 5 -2 -3 -3 -1 -2 -3 -2 0 -1 -3 -3 -2 41 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0.64 0.06
130 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
131 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 41 0.39 0.06
132 G -1 -2 0 -2 -3 -1 -1 5 6 -4 -4 -1 -3 -3 -2 -1 -2 -3 0 -4 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06
133 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 12 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.45 0.06
134 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
135 M -1 -2 -3 -3 -2 -1 -2 -3 -2 1 2 -2 7 0 -3 -2 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0.47 0.06
136 G 0 -2 0 -1 -2 -1 -1 5 -2 -4 -4 -1 -2 -3 -2 3 0 -3 -3 -3 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 41 0 0 0 0 0.64 0.06
137 Q -1 1 0 -1 -3 5 1 -2 0 -3 -3 4 -1 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 59 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0.57 0.06
138 N -2 -1 5 4 -3 0 0 -1 0 -4 -4 -1 -3 -4 -2 0 -1 -4 -3 -3 0 0 59 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.73 0.06
139 F -2 -3 -4 -4 -2 -3 -4 -4 -2 3 1 -3 0 5 -4 -3 -2 0 2 1 0 0 0 0 0 0 0 0 0 41 0 0 0 59 0 0 0 0 0 0 0.50 0.06
140 W -3 -3 -4 -5 -3 -2 -3 -3 -3 -3 -2 -3 -2 1 -4 -3 -3 12 2 -3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 2.45 0.06
141 L -2 -3 -4 -4 -2 -2 -3 -4 -3 1 4 -3 2 0 -3 -3 -1 -2 -1 1 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0.54 0.06
142 K -1 4 0 -1 -4 1 0 -2 -1 -3 -3 4 -2 -3 -2 -1 -1 -3 -2 -3 0 41 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 0.61 0.06
143 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
144 E -1 0 0 1 -4 2 6 -2 0 -4 -3 1 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0.82 0.06
145 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
146 V -1 -3 -3 -4 -1 -3 -3 -4 -4 4 1 -3 1 -1 -3 -2 -1 -3 -2 4 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 0 59 0.42 0.06
147 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
148 S 0 -1 4 0 -2 0 0 -1 0 -3 -3 0 -2 -3 -2 3 1 -4 -2 -2 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0.49 0.06
149 F -1 -3 -3 -4 -2 -3 -3 -4 -2 1 0 -3 0 5 -3 -2 -1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 41 0.47 0.06
150 A 5 -2 -2 -2 -1 -1 -1 0 -2 -2 -2 -1 -1 -3 -1 1 0 -3 -2 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.48 0.06
151 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
152 A 3 -2 -2 -3 -1 -1 -2 -1 -2 0 0 -1 4 -1 -2 0 0 -2 -2 0 59 0 0 0 0 0 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0.28 0.06
153 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
154 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
155 D -2 -1 1 5 -4 1 4 -2 -1 -4 -4 0 -3 -4 -2 0 -1 -4 -3 -3 0 0 0 59 0 0 41 0 0 0 0 0 0 0 0 0 0 0 0 0 0.78 0.06
156 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
157 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
158 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
159 D -2 -2 1 7 -4 -1 1 -2 -1 -4 -4 -1 -3 -4 -2 0 -1 -5 -3 -4 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1.03 0.06
160 K 0 1 0 -1 -2 1 0 -1 -1 -3 -3 4 -2 -3 -1 3 0 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 41 0 0 0 0 0.41 0.06
161 Y -2 -2 -2 -3 -3 -2 -2 -3 2 -2 -1 -2 -1 3 -3 -2 -2 2 8 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0.98 0.06
162 S 0 -1 0 0 -2 1 3 -1 -1 -3 -3 0 -2 -3 -1 3 1 -3 -2 -2 0 0 0 0 0 0 41 0 0 0 0 0 0 0 0 59 0 0 0 0 0.46 0.06
163 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
164 F -1 -3 -3 -4 -2 -3 -3 -4 -2 1 0 -3 0 5 -3 -2 -1 0 2 2 0 0 0 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 41 0.47 0.06
165 Q -1 1 0 -1 -3 6 2 -2 0 -3 -2 1 -1 -4 -2 0 -1 -2 -2 -3 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.75 0.06
166 L -1 -3 -4 -4 -1 -3 -3 -4 -3 2 3 -3 1 0 -3 -2 -1 -2 -1 3 0 0 0 0 0 0 0 0 0 0 59 0 0 0 0 0 0 0 0 41 0.39 0.06
167 S 1 -1 0 0 -1 0 0 0 -1 -3 -3 0 -2 -3 -1 5 1 -3 -2 -2 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0.53 0.06
168 I -2 -3 -4 -4 -2 -3 -3 -4 -3 4 3 -3 1 0 -3 -3 -1 -3 -1 2 0 0 0 0 0 0 0 0 0 59 41 0 0 0 0 0 0 0 0 0 0.43 0.06
169 G 0 -3 -1 -2 -3 -2 -2 6 -2 -4 -4 -2 -3 -4 -2 0 -2 -3 -3 -4 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0 0 0 0 1.13 0.06
170 K -1 2 0 -1 -3 1 1 -2 -1 -3 -3 5 -2 -4 -1 0 -1 -3 -2 -3 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0 0 0.61 0.06
171 Q -1 4 0 -1 -4 5 1 -2 0 -3 -2 2 -1 -3 -2 -1 -1 -3 -2 -3 0 41 0 0 0 59 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0.63 0.06
172 F -3 -3 -3 -4 -3 -4 -4 -4 -2 0 0 -4 0 7 -4 -3 -2 1 3 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 100 0 0 0 0 0 0 0.86 0.06
K Lambda
Standard Ungapped 0.1368 0.3170
Standard Gapped 0.0410 0.2670
PSI Ungapped 0.1506 0.3161
PSI Gapped 0.0461 0.2670
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