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# -*- coding: utf-8 -*-
"""Tests for transfer of knowledge and inference functions."""
import unittest
from pybel.examples.statin_example import (
avorastatin,
ec_11134,
ec_11188,
fluvastatin,
hmgcr,
hmgcr_inhibitor,
mevinolinic_acid,
statin,
statin_graph,
synthetic_statin,
)
from pybel.struct.mutation import infer_child_relations
from pybel.struct.mutation.inference.transfer import iter_children
class TestTransfer(unittest.TestCase):
"""Tests for transfer of knowledge and inference functions."""
def test_get_children(self):
"""Test iterating over the children of a node."""
children = list(iter_children(statin_graph, hmgcr_inhibitor))
self.assertNotEqual(0, len(children), msg="no children found")
self.assertIn(mevinolinic_acid, children, msg="direct child not found")
def test_infer(self):
"""Test inferring child relations."""
graph = statin_graph.copy()
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(8, graph.number_of_edges())
self.assertNotIn(ec_11134, graph[fluvastatin])
self.assertNotIn(ec_11188, graph[fluvastatin])
self.assertNotIn(ec_11134, graph[avorastatin])
self.assertNotIn(ec_11188, graph[avorastatin])
self.assertNotIn(ec_11134, graph[synthetic_statin])
self.assertNotIn(ec_11188, graph[synthetic_statin])
self.assertNotIn(ec_11134, graph[statin])
self.assertNotIn(ec_11188, graph[statin])
self.assertNotIn(ec_11134, graph[mevinolinic_acid])
self.assertNotIn(ec_11188, graph[mevinolinic_acid])
self.assertIn(ec_11134, graph[hmgcr_inhibitor])
self.assertIn(ec_11188, graph[hmgcr_inhibitor])
infer_child_relations(graph, hmgcr_inhibitor)
self.assertIn(ec_11134, graph[fluvastatin])
self.assertIn(ec_11188, graph[fluvastatin])
self.assertIn(ec_11134, graph[avorastatin])
self.assertIn(ec_11188, graph[avorastatin])
self.assertIn(ec_11134, graph[synthetic_statin])
self.assertIn(ec_11188, graph[synthetic_statin])
self.assertIn(ec_11134, graph[statin])
self.assertIn(ec_11188, graph[statin])
self.assertIn(ec_11134, graph[mevinolinic_acid])
self.assertIn(ec_11188, graph[mevinolinic_acid])
self.assertIn(ec_11134, graph[hmgcr_inhibitor])
self.assertIn(ec_11188, graph[hmgcr_inhibitor])
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(18, graph.number_of_edges())
infer_child_relations(graph, ec_11134)
self.assertIn(hmgcr, graph[fluvastatin])
self.assertIn(hmgcr, graph[avorastatin])
self.assertIn(hmgcr, graph[synthetic_statin])
self.assertIn(hmgcr, graph[statin])
self.assertIn(hmgcr, graph[mevinolinic_acid])
self.assertIn(hmgcr, graph[hmgcr_inhibitor])
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(24, graph.number_of_edges())
self.assertEqual(
9,
statin_graph.number_of_nodes(),
msg="original graph nodes should not be modified",
)
self.assertEqual(
8,
statin_graph.number_of_edges(),
msg="original graph edges should not be modified",
)
def test_does_not_redo(self):
"""Test that :func:`propagate_node_relations` does not add the same edges twice."""
graph = statin_graph.copy()
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(8, graph.number_of_edges())
infer_child_relations(graph, hmgcr_inhibitor)
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(18, graph.number_of_edges())
infer_child_relations(graph, hmgcr_inhibitor)
self.assertEqual(9, graph.number_of_nodes())
self.assertEqual(18, graph.number_of_edges(), msg="edges should not be added again")
if __name__ == "__main__":
unittest.main()
|
