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METATOOL OUTPUT Version 3.5 (28.03.2001) C:\METATOOL\META35~1.EXE
INPUT FILE: EXAMPLE15.TXT
INTERNAL METABOLITES: 26
REACTIONS: 11
4 external H2O
2 int NH3
2 int S-Adenosyl-L-methionine
2 int S-adenosyl-L-homocysteine
2 int N-formimino-L-glutamate
1 int RCH2NH2
1 int O2
1 int RCHO
1 int H2O2
1 int carnosine
1 int anserine
1 int histamine
1 int Ntau-methylhistamine
1 int 5-Formiminotetrahydrofolate
1 int L-glutamate
1 int tetrahydrofolate
1 int N-Acetyl-L-aspartate
1 int a_fatty_acid_anion
1 int L-aspartate
1 int 4-Imidazolone-5-propanoate
1 int L-Tryptophan
1 int tryptamine
1 int CO2
1 int Urocanate
1 int 4,5-dihydro-4-oxo-5-imidazolepropanoate
1 int L-Histidine
1 int urocanate
27 metabolites, 34 is the summarized frequency
edges frequency of nodes
0 0
1 22
2 4
3 0
4 1
STOICHIOMETRIC MATRIX
matrix dimension r26 x c11
0 0 -1 0 0 0 0 0 0 0 0
0 0 -1 0 0 0 0 0 0 0 0
0 0 1 0 0 0 0 0 0 0 0
0 1 1 0 0 0 0 0 0 0 0
0 0 1 0 0 0 0 0 0 0 0
0 0 0 -1 -1 0 0 0 0 0 0
0 0 0 -1 0 0 0 0 0 0 0
0 0 0 1 1 0 0 0 0 0 0
0 0 0 1 0 0 0 0 0 0 0
0 0 0 0 -1 0 0 0 0 0 0
0 0 0 0 1 0 0 0 0 0 0
-1 0 0 0 0 0 0 0 0 0 0
-1 0 0 0 0 0 0 0 0 0 0
1 0 0 0 0 0 0 0 0 0 0
1 0 0 0 0 0 0 1 0 0 0
0 0 0 0 0 0 -1 0 0 0 0
0 0 0 0 0 0 1 0 0 0 0
0 0 0 0 0 0 1 0 0 0 0
0 0 0 0 0 0 0 -1 0 0 0
0 0 0 0 0 0 0 0 -1 0 0
0 0 0 0 0 0 0 0 1 0 0
0 0 0 0 0 0 0 0 1 0 0
0 0 0 0 0 0 0 0 0 -1 0
0 0 0 0 0 0 0 0 0 1 0
0 -1 0 0 0 0 0 0 0 0 0
0 1 0 0 0 0 0 0 0 0 0
The following line indicates reversible (0) and irreversible reactions (1)
0 0 1 1 1 1 1 1 1 1 1
rows and columns are sorted as declared in the inputfile
NOT BALANCED INTERNAL METABOLITES
RCH2NH2 O2 RCHO H2O2 carnosine anserine histamine Ntau-methylhistamine 5-Formiminotetrahydrofolate L-glutamate tetrahydrofolate N-Acetyl-L-aspartate a_fatty_acid_anion L-aspartate 4-Imidazolone-5-propanoate L-Tryptophan tryptamine CO2 Urocanate 4,5-dihydro-4-oxo-5-imidazolepropanoate L-Histidine urocanate
KERNEL
matrix dimension r2 x c11
0 0 0 0 0 1 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 1
11 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.
enzymes
1: 2.1.2.5 irreversible
2: 4.3.1.3 irreversible
overall reaction
- not found -
The remaining overall reactions perform no net transformation of external metabolites.
SUBSETS OF REACTIONS
matrix dimension r2 x c11
0 0 0 0 0 1 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 1
11 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.
enzymes
1: 2.1.2.5 irreversible
2: 4.3.1.3 irreversible
overall reaction
- not found -
The remaining overall reactions perform no net transformation of external metabolites.
REDUCED SYSTEM with 26 branch point metabolites in 2 reactions (columns)
matrix dimension r0 x c2
The following line indicates reversible (0) and irreversible reactions (1)
1 1
-> Branch metabolites are :
met cons built reactions
-> No branch metabolites are :
met cons built reactions
RCH2NH2 1 0 1 i
O2 1 0 1 i
RCHO 0 1 1 i
NH3 0 2 2 ir
H2O2 0 1 1 i
S-Adenosyl-L-methionine 2 0 2 ii
carnosine 1 0 1 i
S-adenosyl-L-homocysteine 0 2 2 ii
anserine 0 1 1 i
histamine 1 0 1 i
Ntau-methylhistamine 0 1 1 i
5-Formiminotetrahydrofolate 1 0 1 r
L-glutamate 1 0 1 r
tetrahydrofolate 0 1 1 r
N-formimino-L-glutamate 0 2 2 ri
N-Acetyl-L-aspartate 1 0 1 i
a_fatty_acid_anion 0 1 1 i
L-aspartate 0 1 1 i
4-Imidazolone-5-propanoate 1 0 1 i
L-Tryptophan 1 0 1 i
tryptamine 0 1 1 i
CO2 0 1 1 i
Urocanate 1 0 1 i
4,5-dihydro-4-oxo-5-imidazolepropanoate 0 1 1 i
L-Histidine 1 0 1 r
urocanate 0 1 1 r
CONVEX BASIS
matrix dimension r2 x c11
0 0 0 0 0 1 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 1
enzymes
1: 2.1.2.5 irreversible
2: 4.3.1.3 irreversible
overall reaction
- not found -
The remaining overall reactions perform no net transformation of external metabolites.
CONSERVATION RELATIONS
matrix dimension r17 x c26
1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
1 0 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 1 -1 0 0 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 -1 1 0 0 0 -1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 1 -1 0 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 1 0 0 1 0 0 0 1 0 0 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 1 0 0 0 0
0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 1 0 0
1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0
1 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 -1
1 : RCH2NH2 + O2 = const
2 : RCH2NH2 + RCHO = const
3 : RCH2NH2 + H2O2 = const
4 : S-Adenosyl-L-methionine + S-adenosyl-L-homocysteine = const
5 : carnosine + anserine = const
6 : S-Adenosyl-L-methionine + carnosine + histamine = const
7 : S-Adenosyl-L-methionine + carnosine + Ntau-methylhistamine = const
8 : 5-Formiminotetrahydrofolate + L-glutamate = const
9 : 5-Formiminotetrahydrofolate + tetrahydrofolate = const
10 : N-Acetyl-L-aspartate + a_fatty_acid_anion = const
11 : N-Acetyl-L-aspartate + L-aspartate = const
12 : 5-Formiminotetrahydrofolate + N-formimino-L-glutamate + 4-Imidazolone-5-propanoate = const
13 : L-Tryptophan + tryptamine = const
14 : L-Tryptophan + CO2 = const
15 : Urocanate + 4,5-dihydro-4-oxo-5-imidazolepropanoate = const
16 : RCH2NH2 + NH3 + L-Histidine = const
17 : RCH2NH2 + NH3 + urocanate = const
ELEMENTARY MODES
matrix dimension r2 x c11
0 0 0 0 0 1 0 0 0 0 0
0 0 0 0 0 0 0 0 0 0 1
11 reactions (columns) are sorted in the same order as in the ENZREV ENZIRREV section.
enzymes
1: 2.1.2.5 irreversible
2: 4.3.1.3 irreversible
overall reaction
- not found -
The remaining overall reactions perform no net transformation of external metabolites.
The elementary modes ARE EQUAL to convex basis.
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