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#!/usr/bin/env python
# Copyright 2001 by Brad Chapman. All rights reserved.
# This code is part of the Biopython distribution and governed by its
# license. Please see the LICENSE file that should have been included
# as part of this package.
"""Test the creation of Chromosome Graphics.
Provide tests for creating and manipulating pdf pictures of chromosomes.
This tests the Graphics.BasicChromosome classes and the
Graphics.DisplayRepresentation classes.
"""
# standard library
import os
import sys
import random
import cStringIO
import unittest
from Bio import MissingExternalDependencyError
try:
# reportlab
from reportlab.lib import colors
except:
raise MissingExternalDependencyError(\
"Install reportlab if you want to use Bio.Graphics.")
# local stuff
from Bio.Graphics import BasicChromosome
from Bio.Graphics.DisplayRepresentation import ChromosomeCounts
# hold the chromosome info for testing
# the info is structured as (label, color, scale)
chr1_info = (("", None, 1),
("AC30001", None, 1),
("", colors.blue, 2),
("", colors.blue, 1.5),
("", colors.red, 2),
("AC12345", colors.blue, 1),
("", colors.blue, 1),
("", colors.blue, 1),
("", None, 1))
chr2_info = (("", None, 2),
("AC23456", None, 2),
("", colors.blue, 1),
("", colors.blue, 1),
("", colors.red, 1),
("AC00002", colors.blue, 1.5),
("", colors.blue, 1.5),
("", colors.blue, 2),
("", None, 1.5),
("", colors.red, 2),
("", colors.red, 1.5),
("AB0001", None, 1),
("", colors.red, 1))
chr3_info = (("", colors.green, 2),
("", colors.green, 1),
("AD00002", colors.blue, 1),
("", colors.blue, 1),
("", colors.red, 1))
chr4_info = (("", None, 1.5),
("", None, 1),
("AD11111", colors.blue, 2),
("", colors.blue, 1),
("", colors.red, 1.5),
("", colors.blue, 1),
("", colors.blue, 1),
("AC22222", colors.blue, 1))
all_chr_info = {"I" : chr1_info,
"II" : chr2_info,
"III" : chr3_info,
"IV" : chr4_info}
def load_chromosome(chr_name):
"""Load a chromosome and all of its segments.
"""
cur_chromosome = BasicChromosome.Chromosome(chr_name)
chr_segment_info = all_chr_info[chr_name]
for seg_info_num in range(len(chr_segment_info)):
label, fill_color, scale = chr_segment_info[seg_info_num]
# make the top and bottom telomeres
if seg_info_num == 0:
cur_segment = BasicChromosome.TelomereSegment()
elif seg_info_num == len(chr_segment_info) - 1:
cur_segment = BasicChromosome.TelomereSegment(1)
# otherwise, they are just regular segments
else:
cur_segment = BasicChromosome.ChromosomeSegment()
if label != "":
cur_segment.label = label
if fill_color is not None:
cur_segment.fill_color = fill_color
cur_segment.scale = scale
cur_chromosome.add(cur_segment)
# scale by the size of chromosome 2
cur_chromosome.scale_num = 19
return cur_chromosome
# --- stuff for generating random organisms
color_choices = (colors.red, colors.blue)
letter_choices = '0123456789ABCDEFGHIJKLMNOPQRSTUVWXYZ'
num_possible_segments = 500
color_prob = .3
id_prob = .025
def get_random_id():
"""Generate a random id number.
"""
id = ''
for n in range(6):
letter = random.choice(letter_choices)
id += letter
return id
def load_random_chromosome(chr_name):
"""Generate a chromosome with random information about it.
"""
cur_chromosome = BasicChromosome.Chromosome(chr_name)
num_segments = random.randrange(num_possible_segments)
for seg in range(num_segments):
# make the top and bottom telomeres
if seg == 0:
cur_segment = BasicChromosome.TelomereSegment()
elif seg == num_segments - 1:
cur_segment = BasicChromosome.TelomereSegment(1)
# otherwise, they are just regular segments
else:
cur_segment = BasicChromosome.ChromosomeSegment()
color_chance = random.random()
if color_chance <= color_prob:
fill_color = random.choice(color_choices)
cur_segment.fill_color = fill_color
id_chance = random.random()
if id_chance <= id_prob:
id = get_random_id()
cur_segment.label = id
cur_chromosome.add(cur_segment)
return cur_chromosome, num_segments
class OrganismGraphicTest(unittest.TestCase):
"""Test the creation of all chromosomes of an organism.
"""
def setUp(self):
self.test_file = os.path.join("Graphics", "organism.pdf")
def test_simple_organism(self):
"""Test the basic functionality of drawing an organism.
"""
pdf_organism = BasicChromosome.Organism()
# add chromosomes
for chr_name in ["I", "II", "III", "IV"]:
cur_chromosome = load_chromosome(chr_name)
pdf_organism.add(cur_chromosome)
pdf_organism.draw(self.test_file, "Test organism")
def _simple_organism(self, filename, format):
"""Output a simple organism to given format."""
test_organism = BasicChromosome.Organism(format)
test_file = os.path.join("Graphics", filename)
# add chromosomes
for chr_name in ["I", "II", "III", "IV"]:
cur_chromosome = load_chromosome(chr_name)
test_organism.add(cur_chromosome)
test_organism.draw(test_file, "Test organism")
def test_simple_organism_ps(self):
"""Output a simple organism to a postscript file.
"""
self._simple_organism("organism.eps", "ps")
def test_simple_organism_pdf(self):
"""Output a simple organism to a PDF file.
"""
self._simple_organism("organism.pdf", "pdf")
def test_simple_organism_svg(self):
"""Output a simple organism to an SVG file.
"""
self._simple_organism("organism.svg", "svg")
def test_random_organism(self):
"""Generate an organism with random chromosome info.
"""
random_file = os.path.join("Graphics", "random_organism.pdf")
pdf_organism = BasicChromosome.Organism()
all_segs = []
all_chrs = []
num_chrs = random.randrange(1, 15)
for chr_name in range(num_chrs):
cur_chromosome, num_segs = load_random_chromosome(str(chr_name))
all_chrs.append(cur_chromosome)
all_segs.append(num_segs)
# scale all of the chromosomes by the maximum number of segments
max_segs = max(all_segs)
for chr in all_chrs:
chr.scale_num = max_segs
pdf_organism.add(chr)
pdf_organism.draw(random_file, "Randomly generated Organism")
def test_widget(self):
"""Try widget derived functionality.
"""
test_widget = BasicChromosome.ChromosomeSegment()
expected_string = "chr_percent = 0.25"
# trick to write the properties to a string
save_stdout = sys.stdout
new_stdout = cStringIO.StringIO()
sys.stdout = new_stdout
test_widget.dumpProperties()
properties = new_stdout.getvalue()
sys.stdout = save_stdout
assert properties.find(expected_string) >= 0, \
"Unexpected results from dumpProperties: \n %s" % properties
properties = test_widget.getProperties()
assert properties.has_key("label_size") \
and properties["label_size"] == 6, \
"Unexpected results from getProperties: %s" % properties
test_widget.setProperties({"start_x_position" : 12})
assert test_widget.start_x_position == 12, \
"setProperties doesn't seem to work right: %s" \
% test_widget.start_x_position
class ChromosomeCountTest(unittest.TestCase):
"""Test the display representation for simple counts on a chromosome.
"""
def setUp(self):
self.names = ["Bob", "Dylan", "Doesn't", "Like", "Spam"]
self.count_display = ChromosomeCounts(self.names)
def test_add_count(self):
"""Add counts to specific chromosome segments.
"""
self.count_display.add_count(self.names[1])
self.count_display.add_count(self.names[2], 5)
try:
self.count_display.add_count("Non-existent")
raise AssertionError("Didn't raise a KeyError on a fake key")
except KeyError:
pass
def test_add_label(self):
"""Add labels to chromosome segments.
"""
self.count_display.add_label(self.names[1], "Rules")
try:
self.count_display.add_label("Non-existent", "Elephant")
raise AssertionError("Didn't raise a KeyError on a fake key")
except KeyError:
pass
def test_set_scale(self):
"""Set the scale for a chromosome segment.
"""
self.count_display.set_scale(self.names[1], 1.5)
try:
self.count_display.set_scale("Non-existant", 5)
raise AssertionError("Didn't raise a KeyError on a fake key.")
except KeyError:
pass
def test_color_from_count(self):
"""Retrieve a color from a count number with the default color scheme.
"""
test_color = self.count_display._color_from_count(3)
assert test_color == colors.blue, "Unexpected color %s" % test_color
test_color = self.count_display._color_from_count(9)
assert test_color == colors.red, "Unexpected color %s" % test_color
try:
self.count_display._color_from_count(200)
raise AssertionError("Didn't raise an error for bad count.")
except ValueError:
pass
def test_fill_chromosome(self):
"""Test filling out the information on a chromosome.
"""
test_chr = BasicChromosome.Chromosome("1")
self.count_display.add_count(self.names[2], 5)
self.count_display.add_count(self.names[1], 2)
self.count_display.add_label(self.names[3], "Test-Label")
new_chr = self.count_display.fill_chromosome(test_chr)
def test_get_segment_info(self):
"""Test retrieval of segment information.
"""
test_count_num = 1
test_count_value = 5
test_label_num = 3
test_label_value = "BigBird"
self.count_display.add_count(self.names[test_count_num],
test_count_value)
self.count_display.add_label(self.names[test_label_num],
test_label_value)
seg_info = self.count_display.get_segment_info()
assert seg_info[test_count_num][0] == test_count_value, \
"Did not set and retrieve counts correctly."
assert seg_info[test_label_num][1] == test_label_value, \
"Did not set and retrieve label correctly."
if __name__ == "__main__":
runner = unittest.TextTestRunner(verbosity = 2)
unittest.main(testRunner=runner)
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