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|
LOCUS AE006468 4857432 bp DNA circular BCT 23-FEB-2009
DEFINITION Salmonella enterica subsp. enterica serovar Typhimurium str. LT2,
complete genome.
ACCESSION AE006468 AE008693-AE008916
VERSION AE006468.1 GI:16445344
DBLINK Project:241
KEYWORDS .
SOURCE Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
ORGANISM Salmonella enterica subsp. enterica serovar Typhimurium str. LT2
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales;
Enterobacteriaceae; Salmonella; Salmonella enterica subsp. enterica
serovar Typhimurium.
REFERENCE 1 (bases 1 to 4857432)
AUTHORS McClelland,M., Sanderson,K.E., Spieth,J., Clifton,S.W.,
Latreille,P., Courtney,L., Porwollik,S., Ali,J., Dante,M., Du,F.,
Hou,S., Layman,D., Leonard,S., Nguyen,C., Scott,K., Holmes,A.,
Grewal,N., Mulvaney,E., Ryan,E., Sun,H., Florea,L., Miller,W.,
Stoneking,T., Nhan,M., Waterston,R. and Wilson,R.K.
TITLE Complete genome sequence of Salmonella enterica serovar Typhimurium
LT2
JOURNAL Nature 413 (6858), 852-856 (2001)
PUBMED 11677609
REFERENCE 2 (bases 1 to 4857432)
CONSRTM The Salmonella typhimurium Genome Sequencing Project
TITLE Direct Submission
JOURNAL Submitted (29-MAR-2001) Genome Sequencing Center, Department of
Genetics, Washington University School of Medicine, 4444 Forest
Park Boulevard, St. Louis, MO 63108, USA
COMMENT On or before Feb 20, 2009 this sequence version replaced
gi:16418493, gi:16418512, gi:16418529, gi:16418549, gi:16418569,
gi:16418591, gi:16418608, gi:16418628, gi:16418650, gi:16418668,
gi:16418689, gi:16418705, gi:16418723, gi:16418742, gi:16418760,
gi:16418784, gi:16418804, gi:16418824, gi:16418844, gi:16418861,
gi:16418878, gi:16418900, gi:16418921, gi:16418944, gi:16418964,
gi:16418985, gi:16419003, gi:16419024, gi:16419047, gi:16419070,
gi:16419090, gi:16419110, gi:16419136, gi:16419161, gi:16419181,
gi:16419199, gi:16419219, gi:16419241, gi:16419261, gi:16419282,
gi:16419303, gi:16419326, gi:16419345, gi:16419364, gi:22024638,
gi:16419449, gi:16419469, gi:16419487, gi:22024639, gi:16419572,
gi:16419592, gi:16419620, gi:16419641, gi:16419665, gi:16419687,
gi:16419709, gi:16419731, gi:16419750, gi:16419776, gi:16419802,
gi:16419825, gi:16419849, gi:16419870, gi:16419888, gi:16419908,
gi:16419944, gi:16419969, gi:16419990, gi:16420008, gi:16420030,
gi:16420061, gi:16420079, gi:16420095, gi:16420112, gi:16420132,
gi:16420154, gi:16420173, gi:16420194, gi:16420213, gi:16420237,
gi:16420258, gi:16420281, gi:16420298, gi:16420325, gi:16420348,
gi:16420369, gi:16420391, gi:16420418, gi:16420438, gi:16420461,
gi:16420488, gi:16420517, gi:16420539, gi:16420565, gi:16420590,
gi:16420610, gi:16420630, gi:16420649, gi:16420666, gi:16420687,
gi:16420709, gi:16420731, gi:16420749, gi:16420769, gi:16420795,
gi:16420811, gi:16420832, gi:16420856, gi:16420874, gi:16420896,
gi:16420916, gi:16420938, gi:16420955, gi:16420979, gi:16421005,
gi:16421023, gi:16421046, gi:16421058, gi:16421075, gi:16421092,
gi:16421111, gi:16421131, gi:16421159, gi:16421190, gi:16421206,
gi:16421230, gi:16421239, gi:16421268, gi:16421292, gi:16421311,
gi:16421327, gi:16421347, gi:16421370, gi:16421388, gi:16421412,
gi:16421434, gi:16421460, gi:16421485, gi:16421501, gi:16421517,
gi:16421536, gi:16421550, gi:16421569, gi:16421592, gi:16421612,
gi:16421636, gi:16421663, gi:16421682, gi:16421705, gi:16421729,
gi:16421751, gi:16421769, gi:16421791, gi:16421808, gi:16421834,
gi:16421851, gi:16421879, gi:16421897, gi:16421920, gi:16421939,
gi:16421954, gi:16421987, gi:16422017, gi:16422036, gi:16422058,
gi:16422074, gi:16422092, gi:16422111, gi:16422137, gi:16422156,
gi:16422173, gi:16422188, gi:16422205, gi:16422228, gi:16422247,
gi:16422263, gi:16422283, gi:16422308, gi:16422324, gi:16422343,
gi:16422367, gi:16422393, gi:16422410, gi:16422430, gi:16422449,
gi:16422464, gi:16422484, gi:16422503, gi:16422527, gi:16422547,
gi:16422561, gi:16422586, gi:16422609, gi:16422630, gi:16422654,
gi:16422675, gi:16422691, gi:16422706, gi:16422728, gi:16422744,
gi:16422768, gi:16422789, gi:16422815, gi:16422822, gi:16422843,
gi:16422860, gi:16422882, gi:16422906, gi:16422923, gi:16422950,
gi:16422976, gi:16422994, gi:16423017, gi:16423037, gi:16423054,
gi:16423067, gi:16423088, gi:16423108, gi:16423133, gi:16423153.
Supported by NIH grant 5U 01 AI43283
Coding sequences below are predicted from manually evaluated
computer analysis, using similarity information and the programs;
GLIMMER; http://www.tigr.org/softlab/glimmer/glimmer.html and
GeneMark; http://opal.biology.gatech.edu/GeneMark/
EC numbers were kindly provided by Junko Yabuzaki and the Kyoto
Encyclopedia of Genes and Genomes; http://www.genome.ad.jp/kegg/,
and Pedro Romero and Peter Karp at EcoCyc;
http://ecocyc.PangeaSystems.com/ecocyc/
The analyses of ribosome binding sites and promoter binding sites
were kindly provided by Heladia Salgado, Julio Collado-Vides and
ReguonDB;
http://kinich.cifn.unam.mx:8850/db/regulondb_intro.frameset
This sequence was finished as follows unless otherwise noted: all
regions were double stranded, sequenced with an alternate
chemistries or covered by high quality data (i.e., phred quality >=
30); an attempt was made to resolve all sequencing problems, such
as compressions and repeats; all regions were covered by sequence
from more than one m13 subclone.
FEATURES Location/Qualifiers
source join(1..962611,1004276..1098227,1143715..2728971,
2776823..2844426,2879234..4857432)
/organism="Salmonella enterica subsp. enterica serovar
Typhimurium str. LT2"
/mol_type="genomic DNA"
/strain="LT2; SGSC 1412; ATCC 700720"
/serovar="Typhimurium"
/culture_collection="ATCC:700720"
/db_xref="taxon:99287"
/focus
source 962612..1004275
/organism="Salmonella phage Fels-1"
/mol_type="genomic DNA"
/db_xref="taxon:128975"
source 1098228..1143714
/organism="Phage Gifsy-2"
/mol_type="genomic DNA"
/db_xref="taxon:129862"
source 2728972..2776822
/organism="Phage Gifsy-1"
/mol_type="genomic DNA"
/db_xref="taxon:129861"
source 2844427..2879233
/organism="Enterobacteria phage Fels-2"
/mol_type="genomic DNA"
/db_xref="taxon:194701"
gene 190..255
/gene="thrL"
/locus_tag="STM0001"
CDS 190..255
/gene="thrL"
/locus_tag="STM0001"
/note="similar to E. coli thr operon leader peptide
(AAC73112.1); Blastp hit to AAC73112.1 (21 aa),
85-1073758644dentity in aa 1 - 21"
/codon_start=1
/transl_table=11
/product="thr operon leader peptide"
/protein_id="AAL18965.1"
/db_xref="GI:16418494"
/translation="MNRISTTTITTITITTGNGAG"
gene 325..2799
/gene="thrA"
/locus_tag="STM0002"
RBS 325..330
/gene="thrA"
/locus_tag="STM0002"
/note="putative RBS for thrA; RegulonDB:STMS1H000398"
CDS 337..2799
/gene="thrA"
/locus_tag="STM0002"
/EC_number="1.1.1.3"
/EC_number="2.7.2.4"
/note="bifunctional; N-terminaus is aspartokinase I and C
terminus is homoserine dehydrogenase I; similar to E. coli
aspartokinase I, homoserine dehydrogenase I (AAC73113.1);
Blastp hit to AAC73113.1 (820 aa), 94% identity in aa 1 -
820"
/codon_start=1
/transl_table=11
/product="aspartokinase I"
/protein_id="AAL18966.1"
/db_xref="GI:16418495"
/translation="MRVLKFGGTSVANAERFLRVADILESNARQGQVATVLSAPAKIT
NHLVAMIEKTIGGQDALPNISDAERIFSDLLAGLASAQPGFPLARLKMVVEQEFAQIK
HVLHGISLLGQCPDSINAALICRGEKMSIAIMAGLLEARGHRVTVIDPVEKLLAVGHY
LESTVDIAESTRRIAASQIPADHMILMAGFTAGNEKGELVVLGRNGSDYSAAVLAACL
RADCCEIWTDVDGVYTCDPRQVPDARLLKSMSYQEAMELSYFGAKVLHPRTITPIAQF
QIPCLIKNTGNPQAPGTLIGASSDDDNLPVKGISNLNNMAMFSVSGPGMKGMIGMAAR
VFAAMSRAGISVVLITQSSSEYSISFCVPQSDCARARRAMQDEFYLELKEGLLEPLAV
TERLAIISVVGDGMRTLRGISAKFFAALARANINIVAIAQGSSERSISVVVNNDDATT
GVRVTHQMLFNTDQVIEVFVIGVGGVGGALLEQLKRQQTWLKNKHIDLRVCGVANSKA
LLTNVHGLNLDNWQAELAQANAPFNLGRLIRLVKEYHLLNPVIVDCTSSQAVADQYAD
FLREGFHVVTPNKKANTSSMDYYHQLRFAAAQSRRKFLYDTNVGAGLPVIENLQNLLN
AGDELQKFSGILSGSLSFIFGKLEEGMSLSQATALAREMGYTEPDPRDDLSGMDVARK
LLILARETGRELELSDIVIEPVLPNEFDASGDVTAFMAHLPQLDDAFAARVAKARDEG
KVLRYVGNIEEDGVCRVKIAEVDGNDPLFKVKNGENALAFYSHYYQPLPLVLRGYGAG
NDVTAAGVFADLLRTLSWKLGV"
gene 2789..3730
/gene="thrB"
/locus_tag="STM0003"
RBS 2789..2794
/gene="thrB"
/locus_tag="STM0003"
/note="putative RBS for thrB; RegulonDB:STMS1H000399"
CDS 2801..3730
/gene="thrB"
/locus_tag="STM0003"
/EC_number="2.7.1.39"
/note="similar to E. coli homoserine kinase (AAC73114.1);
Blastp hit to AAC73114.1 (310 aa), 93% identity in aa 1 -
308"
/codon_start=1
/transl_table=11
/product="homoserine kinase"
/protein_id="AAL18967.1"
/db_xref="GI:16418496"
/translation="MVKVYAPASSANMSVGFDVLGAAVTPVDGTLLGDVVSVEAADHF
RLHNLGRFADKLPPEPRENIVYQCWERFCQALGKTIPVAMTLEKNMPIGSGLGSSACS
VVAALVAMNEHCGKPLNDTRLLALMGELEGRISGSIHYDNVAPCFLGGMQLMIEENGI
ISQQVPGFDEWLWVLAYPGIKVSTAEARAILPAQYRRQDCIAHGRHLAGFIHACYSRQ
PQLAAALMKDVIAEPYRARLLPGFSQARQAVSEIGALASGISGSGPTLFALCDKPETA
QRVADWLSKHYLQNQEGFVHICRLDTAGARVVG"
gene 3722..5020
/gene="thrC"
/locus_tag="STM0004"
RBS 3722..3727
/gene="thrB"
/locus_tag="STM0003"
/note="putative RBS for thrC; RegulonDB:STMS1H000400"
CDS 3734..5020
/gene="thrC"
/locus_tag="STM0004"
/EC_number="4.2.3.1"
/note="similar to E. coli threonine synthase (AAC73115.1);
Blastp hit to AAC73115.1 (428 aa), 93% identity in aa 1 -
428"
/codon_start=1
/transl_table=11
/product="threonine synthase"
/protein_id="AAL18968.1"
/db_xref="GI:16418497"
/translation="MKLYNLKDHNEQVSFAQAVTQGLGKQQGLFFPHDLPEFSLTEID
EMLNQDFVSRSAKILSAFIGDEIPQQILEERVRAAFAFPAPVAQVESDVGCLELFHGP
TLAFKDFGGRFMAQMLTHISGDKPVTILTATSGDTGAAVAHAFYGLENVRVVILYPRG
KISPLQEKLFCTLGGNIETVAIDGDFDACQALVKQAFDDEELKTALGLNSANSINISR
LLAQICYYFEAVAQLPQGARNQLVISVPSGNFGDLTAGLLAKSLGLPVKRFIAATNVN
DTVPRFLHDGKWAPKATQATLSNAMDVSQPNNWPRVEELFRRKIWRLTELGYAAVDDT
TTQQTMRELKAKGYISEPHAAVAYRALRDQLNPGEYGLFLGTAHPAKFKESVESILGE
TLALPEALAERADLPLLSHHLPADFAALRKLMMTRQ"
gene complement(5114..5898)
/gene="yaaA"
/locus_tag="STM0005"
CDS complement(5114..5887)
/gene="yaaA"
/locus_tag="STM0005"
/note="similar to E. coli orf, hypothetical protein
(AAC73117.1); Blastp hit to AAC73117.1 (258 aa), 86%
identity in aa 1 - 257"
/codon_start=1
/transl_table=11
/product="putative cytoplasmic protein"
/protein_id="AAL18969.1"
/db_xref="GI:16418498"
/translation="MLILISPAKTLDYQSPLATTRYTQPELLDHSQQLIQQARQLSAP
QISRLMGISDKLADLNATRFHDWQPHFTPDNARQAILAFKGDVYTGLQAETFNDADFD
FAQQHLRMLSGLYGVLRPLDLMQPYRLEMGIRLENPRGKDLYQFWGDIITDKLNEALE
AQGDRVVVNLASEEYFKSVKPKKLNAELIKPVFLDEKNGKFKVVSFYAKKARGLMSRF
IIENRLTKPEQLTAFDREGYFFDEETSTQDELVFKRYEQ"
RBS complement(5893..5898)
/gene="yaaA"
/locus_tag="STM0005"
/note="putative RBS for yaaA; RegulonDB:STMS1H000401"
gene complement(5966..7407)
/gene="yaaJ"
/locus_tag="STM0006"
CDS complement(5966..7396)
/gene="yaaJ"
/locus_tag="STM0006"
/note="AGCS family; similar to E. coli inner membrane
transport protein (AAC73118.1); Blastp hit to AAC73118.1
(476 aa), 76% identity in aa 1 - 476"
/codon_start=1
/transl_table=11
/product="putative alanine/glycine transport protein"
/protein_id="AAL18970.1"
/db_xref="GI:16418499"
/translation="MPEFFSFINEILWGSVMIYLLLGAGCWFTWRTGFIQFRYIRQFS
RSLKGSLSPQPGGLTSFQALCTSLAARIGSGNLAGVALAIAAGGPGAVFWMWVSAIIG
MATSFAECSLAQLYKERDPTGQFRGGPAWYMARGLGMRWMGVVFALFLLVAYGLIFNS
VQANAVSRALHFAFNIPPLISGIALAFCALLIIIRGIKGVARLMQWLIPLIALLWVAG
SVFICLWHIEQMPGVIASIVKSAFGWQEAAAGAAGYTLTQAITSGFQRGMFSNEAGMG
STPNAAAAATSYPPHPVAQGIVQMIGVFSDTIIICTASAMIILLAGNHASHSSTEGIQ
LLQHAMVSLTGEWGASFVALIVILFAFSSIVANYIYAENNLFFLRLHNAKAIWLLRLA
TLGMVIAGTLISFPLIWQLADMIMACMAITNLTAILLLSPVVYTLASDYLRQRKLGVR
PQFDPRRFPDIEPQLAPDTWEAASRD"
RBS complement(7402..7407)
/gene="yaaJ"
/locus_tag="STM0006"
/note="putative RBS for yaaJ; RegulonDB:STMS1H000402"
gene 7652..8618
/gene="talB"
/locus_tag="STM0007"
RBS 7652..7657
/gene="talB"
/locus_tag="STM0007"
/note="putative RBS for talB; RegulonDB:STMS1H000403"
CDS 7665..8618
/gene="talB"
/locus_tag="STM0007"
/EC_number="2.2.1.2"
/note="similar to E. coli transaldolase B (AAC73119.1);
Blastp hit to AAC73119.1 (317 aa), 94% identity in aa 1 -
317"
/codon_start=1
/transl_table=11
/product="transaldolase B"
/protein_id="AAL18971.1"
/db_xref="GI:16418500"
/translation="MTDKLTSLRQFTTVVADTGDIAAMKLYQPQDATTNPSLILNAAQ
IPEYRKLIDDAVAWAKQQSSDRAQQVVDATDKLAVNIGLEILKLVPGRISTEVDARLS
YDTEASIAKAKRIIKLYNDAGISNDRILIKLASTWQGIRAAEQLEKEGINCNLTLLFS
FAQARACAEAGVYLISPFVGRILDWYKANTDKKDYAPAEDPGVVSVTEIYEYYKQHGY
ETVVMGASFRNVGEILELAGCDRLTIAPALLKELAESEGAIERKLSFSGEVKARPERI
TEAEFLWQHHQDPMAVDKLADGIRKFAVDQEKLEKMIGDLL"
gene 8718..9319
/gene="mog"
/locus_tag="STM0008"
RBS 8718..8723
/gene="mog"
/locus_tag="STM0008"
/note="putative RBS for mog; RegulonDB:STMS1H000404"
CDS 8729..9319
/gene="mog"
/locus_tag="STM0008"
/note="molybdopterine biosynthesis; similar to E. coli
required for the efficient incorporation of molybdate into
molybdoproteins (AAC73120.1); Blastp hit to AAC73120.1
(195 aa), 91% identity in aa 1 - 192"
/codon_start=1
/transl_table=11
/product="putative molybdochetalase"
/protein_id="AAL18972.1"
/db_xref="GI:16418501"
/translation="MDTLRIGLVSISDRASSGVYQDKGIPALEEWLASALTTPFEVQR
RLIPDEQEIIEQTLCELVDEMSCHLVLTTGGTGPARRDVTPDATLAIADREMPGFGEQ
MRQISLRFVPTAILSRQVGVIRKQALILNLPGQPKSIKETLEGVKADDGSVSVPGIFA
SVPYCIQLLDGPYVETAPEVVAAFRPKSARRENMSD"
gene complement(9376..9950)
/gene="yaaH"
/locus_tag="STM0009"
CDS complement(9376..9942)
/gene="yaaH"
/locus_tag="STM0009"
/note="similar to E. coli orf, hypothetical protein
(AAC73121.1); Blastp hit to AAC73121.1 (188 aa), 90%
identity in aa 1 - 188"
/codon_start=1
/transl_table=11
/product="putative regulatory protein"
/protein_id="AAL18973.1"
/db_xref="GI:16418502"
/translation="MGNTKLANPAPLGLMGFGMTTILLNLHNAGFFALDGIILAMGIF
YGGIAQIFAGLLEYKKGNTFGLTAFTSYGSFWLTLVAILLMPKMGLTDAPDAQLLGAY
LGLWGVFTLFMFFGTLKAARALQFVFLSLTVLFALLAVGNITGNEATIHIAGWVGLVC
GASAIYLAMGEVLNEQFGRTILPIGEAH"
RBS complement(9945..9950)
/gene="yaaH"
/locus_tag="STM0009"
/note="putative RBS for yaaH; RegulonDB:STMS1H000405"
ORIGIN
1 agagattacg tctggttgca agagatcatg acagggggaa ttggttgaaa ataaatatat
61 cgccagcagc acatgaacaa gtttcggaat gtgatcaatt taaaaattta ttgacttagg
121 cgggcagata ctttaaccaa tataggaata caagacagac aaataaaaat gacagagtac
181 acaacatcca tgaaccgcat cagcaccacc accattacca ccatcaccat taccacaggt
241 aacggtgcgg gctgacgcgt acaggaaaca cagaaaaaag cccgcacctg aacagtgcgg
301 gctttttttt cgaccagaga tcacgaggta acaaccatgc gagtgttgaa gttcggcggt
361 acatcagtgg caaatgcaga acgttttctg cgtgttgccg atattctgga aagcaatgcc
421 aggcaagggc aggtagcgac cgtactttcc gcccccgcga aaattaccaa ccatctggtg
481 gcaatgattg aaaaaactat cggcggccag gatgctttgc cgaatatcag cgatgcagaa
541 cgtatttttt ctgacctgct cgcaggactt gccagcgcgc agccgggatt cccgcttgca
601 cggttgaaaa tggttgtcga acaagaattc gctcagatca aacatgttct gcatggtatc
661 agcctgctgg gtcagtgccc ggatagcatc aacgccgcgc tgatttgccg tggcgaaaaa
721 atgtcgatcg cgattatggc gggacttctg gaggcgcgtg ggcatcgcgt cacggtgatc
781 gatccggtag aaaaattgct ggcggtgggc cattaccttg aatctaccgt tgatatcgcg
841 gaatcgactc gccgtatcgc cgccagccag atcccggccg atcacatgat cctgatggcg
901 ggctttaccg ccggtaatga aaagggtgaa ctggtggtgc tgggccgtaa tggttccgac
961 tattccgccg ccgtgctggc cgcctgttta cgcgctgact gctgtgaaat ctggactgac
1021 gtcgatggcg tgtatacctg tgacccgcgc caggtgccgg acgccaggct gctgaaatcg
1081 atgtcctacc aggaagcgat ggaactctct tacttcggcg ccaaagtcct tcaccctcgc
1141 accattacgc ccatcgccca gttccagatc ccctgtctga ttaaaaatac cggtaatccg
1201 caggcgccag gaacgctgat cggcgcgtcc agcgacgatg ataacctgcc ggttaaaggg
1261 atctctaacc ttaacaacat ggcgatgttt agcgtctccg gcccgggaat gaaagggatg
1321 attgggatgg cggcgcgtgt tttcgccgcc atgtctcgcg ccgggatctc ggtggtgctc
1381 attacccagt cctcctctga gtacagcatc agtttctgtg tgccgcagag tgactgcgcg
1441 cgtgcccgcc gtgcgatgca ggatgagttc tatctggagc tgaaagaggg gctgctggag
1501 ccgctggcgg ttacggagcg gttggcgatt atctctgttg tcggcgacgg tatgcgcacg
1561 ctacgcggca tttcagcgaa attcttcgcc gcgctggcgc gggctaatat caatatcgtg
1621 gcgatcgctc agggatcttc tgagcgttct atttctgtgg tggtgaataa cgacgatgcc
1681 accaccggcg tgcgggtaac gcaccagatg ctgttcaata ccgatcaggt gattgaagtg
1741 tttgtcattg gcgtcggcgg cgtcggcggc gcgctactgg aacagcttaa acgtcagcaa
1801 acctggctga agaacaagca catcgatcta cgcgtgtgcg gcgtggcgaa ctcaaaggcg
1861 ttgctaacca atgtgcatgg cctgaatctg gacaactggc aggcggaact ggcgcaagcg
1921 aacgcgccgt tcaatctggg acgcttaatt cgcctggtga aagaatatca tctactcaat
1981 ccggtgattg ttgattgtac ctccagtcag gcggtggccg accagtatgc cgacttcctg
2041 cgtgaagggt tccatgtggt gacgccaaac aagaaagcga acacctcgtc aatggactac
2101 taccatcagc tacgtttcgc cgccgcgcaa tcacggcgca aattcttgta tgacaccaac
2161 gtcggcgccg gtttgccggt aatcgaaaac ctgcaaaacc tgctgaatgc cggtgatgaa
2221 ctgcaaaaat tttccggcat tctttccggg tcgctctctt ttattttcgg taaactggaa
2281 gaggggatga gtctctcaca ggcgaccgcc ctggcgcgcg agatgggcta taccgaaccc
2341 gatccgcgcg acgatctttc cggtatggat gtggcgcgta aactgttgat cctcgcccgc
2401 gagacgggcc gcgagctgga gctttccgat attgtgattg aaccggtgtt gccgaacgag
2461 tttgacgcct ccggcgatgt gaccgccttt atggcacatc tgccgcagct tgacgacgcg
2521 tttgccgccc gtgtggcgaa agctcgtgat gaaggtaagg tattgcgcta tgtgggcaat
2581 atcgaagagg atggcgtgtg ccgcgtgaaa attgccgaag ttgatggtaa cgatccgctc
2641 ttcaaagtga aaaacggtga aaacgcgctg gcgttctaca gccactatta tcagcccttg
2701 ccgttggtgc tgcgcggcta cggcgcaggc aatgatgtga cggcggcggg cgtgtttgcc
2761 gatctgttac ggaccctctc atggaagtta ggagtttaac atggtgaaag tgtatgcccc
2821 ggcttccagc gcgaacatga gcgtcggttt cgacgtgttg ggcgcagccg tcacacccgt
2881 tgacggcacg ttgctgggcg atgtggtatc cgttgaagca gcggaccatt tccgtctgca
2941 taacctgggg cgatttgccg ataaactgcc gccggagccg cgtgaaaata ttgtttatca
3001 gtgctgggaa cgtttttgcc aggcattggg gaaaaccatc ccggtggcga tgacgctgga
3061 aaaaaatatg ccgattggtt ccgggttagg gtccagcgcc tgttccgtcg tcgccgcgct
3121 ggtcgcgatg aatgagcact gcggcaaacc gttaaacgac acgcgtctgt tggcgctgat
3181 gggcgagctg gaaggccgta tctccggcag catccattac gataacgtcg cgccgtgctt
3241 tcttggcggt atgcagttga tgattgaaga aaacggcatt attagtcagc aggtgccggg
3301 ctttgatgag tggctatggg tactggctta tccgggcatt aaagtttcta ccgcagaagc
3361 acgggccatt ttgcctgcgc agtatcgccg tcaggattgc attgcgcatg gacggcatct
3421 ggccggtttt attcacgcct gttactcgcg gcagccgcag cttgccgccg cgctgatgaa
3481 agatgttatt gccgaaccat accgcgcgcg tttactgccg ggctttagcc aggcgcggca
3541 ggcggtgtcg gagatcggcg cgctggcgag cgggatttcc gggtcggggc cgacgctgtt
3601 tgcgctatgc gataaaccgg agacggcgca gcgcgtcgcg gactggctga gcaaacatta
3661 tctgcaaaat caggaaggct tcgttcatat ttgccggctg gatacggcgg gcgcacgagt
3721 agtgggataa tcaatgaaac tctataatct gaaagaccat aatgagcagg tcagctttgc
3781 gcaggccgtc acgcaaggac tgggcaaaca gcagggactt ttttttccgc acgatctgcc
3841 ggagtttagc ctgacggaaa ttgatgagat gctcaaccag gactttgtca gccgtagcgc
3901 aaagatcctc tcggcattta ttggcgatga aataccgcag caaattctgg aagagcgcgt
3961 ccgcgcggcg tttgcgttcc cggcaccggt agcgcaggta gaaagcgatg tcggctgcct
4021 ggagctgttc catggtccga cgctggcctt taaagacttc ggcgggcgtt ttatggcgca
4081 aatgctgacg catatcagcg gcgacaaacc ggtgacgatt ctgactgcaa cgtcaggcga
4141 taccggcgcg gcggtggctc acgcgttcta tggcctggaa aatgtgcggg tcgtcattct
4201 ctacccgcgc ggtaagatca gtccgttgca ggaaaaactg ttctgtacgc tgggcggcaa
4261 cattgaaacc gtggcgatcg acggcgattt cgacgcgtgc caggcgctgg tgaaacaggc
4321 atttgatgac gaagaactga aaacggcgct ggggctgaat tcggctaatt cgattaatat
4381 cagccgcctg ttggcgcaaa tttgctacta ctttgaagcc gtggcgcaac tgccgcaggg
4441 ggcgcgtaac caactggtga tctccgtccc cagcggcaac tttggcgatt tgacggcagg
4501 gctgctggcg aagtcgttag gcctaccggt gaaacgtttt atcgccgcca ccaacgtcaa
4561 cgacacggtg ccgcgttttc tgcatgacgg aaagtgggcg ccgaaagcga cgcaggcgac
4621 cctgtcgaat gcgatggatg tcagccagcc gaataactgg ccgcgcgtgg aggagctatt
4681 ccgccgtaaa atctggcgcc tgactgagct gggctatgcg gcggtggatg atactacgac
4741 acagcagacg atgcgcgagc tgaaagcgaa aggttatatc tcggaacctc atgcggcggt
4801 agcgtatcgg gcattacgcg accagttaaa ccctggcgag tatggcttgt ttctcggaac
4861 ggcgcatccg gcgaagttta aagagagcgt ggagtccatt ctgggagaaa cgctggcctt
4921 gcctgaagcg ctcgccgaac gcgccgacct gccgctgctt tcacatcatc tgcctgcgga
4981 ttttgccgcc ctgcgtaagc tgatgatgac ccgccaataa ccattgcgcc cggtggcgct
5041 gtcgcttacc gggcctatgg ggtggtgtcg atttgtaggc cggataaggc gtaaccgcca
5101 tccggcgatg ccgttactgc tcgtagcgtt taaagaccag ctcgtcttgt gtggaggttt
5161 cttcatcaaa gaaataccct tcacggtcaa acgcggtaag ctgttccggc ttcgttaagc
5221 ggttttcaat aataaaacgg ctcatcagtc cgcgcgcttt tttggcgtag aagcttacca
5281 ccttaaactt gccgtttttc tcatcaagga acacgggctt aatcagttcg gcattcagtt
5341 tcttcggctt caccgattta aaatattcct cggaggccag attcaccacc acccgatcgc
5401 cctgcgcctc aagcgcttcg ttgagcttat cggtaatgat atcgccccag aattgataaa
5461 gatctttgcc gcgcggattc tccaggcgaa tccccatctc cagacgataa ggctgcatta
5521 aatccagcgg gcgcaatacg ccatacaagc cagagagcat acgcagatgt tgttgagcaa
5581 aatcaaaatc cgcgtcgttg aacgtttccg cctgtaggcc ggtataaaca tcgcctttga
5641 acgccagaat cgcctggcgt gcattatccg gcgtaaaatg aggctgccag tcatgaaaac
5701 gcgtggcgtt gagatccgcc agtttgtcgc taattcccat cagcctggaa atttgcggcg
5761 ccgaaagctg gcgggcctgt tgaataagct gctggctgtg atccaacagc tccggctggg
5821 tatagcgggt cgtggccagc gggctttgat aatcaagcgt ttttgcaggt gaaatcagaa
5881 tcagcatatt cagtccttgc agggaatttt ctgcgacttt agcaaaaaaa cgccgcagag
5941 ttgaccgatg gttgcgattg tcggcttaat cgcgcgatgc cgcctcccag gtatctggcg
6001 ccagttgtgg ttcgatatcc gggaagcgcc gcggatcgaa ctgcggtctt acgcccagtt
6061 tccgttgtcg cagataatcg ctggcgaggg tatacaccac cggtgagagc aacaaaatcg
6121 ccgtcagatt ggtaatggcc atacaggcca tgatcatgtc agcgagctgc catatcagcg
6181 gaaaactgat aagcgtaccg gcgataacca tgccaagcgt cgcaaggcgt aatagccaga
6241 tagcctttgc gttatgtaac cgcagaaaaa acagattgtt ttcggcgtaa atatagttgg
6301 cgacgataga actgaacgcg aacagaatga cgataagcgc gacaaaactg gcgccccatt
6361 caccggtcaa cgaaaccatt gcatgttgga gaagctgaat gccttctgtt gacgagtggg
6421 acgcgtgatt ccccgccagc aggataatca tcgcgctggc ggtacagatg ataatggtgt
6481 cgctgaatac gccaatcatt tgcacaatcc cctgcgcgac agggtgaggg ggatacgacg
6541 ttgccgctgc ggccgcatta ggcgttgacc ccattcccgc ttcattagag aacatcccac
6601 gctgaaaacc gctggtaata gcctgggtga gcgtatatcc ggctgcgcct gccgcggctt
6661 cctgccagcc aaatgcgctt ttgactatcg aggcgataac gccaggcatt tgctcaatat
6721 gccagaggca aatgaatacg ctgccggcga cccacaataa cgcgatgagg ggaatcagcc
6781 attgcatcag acgggcgacg cctttgatgc cgcgaatgat aattaacagg gcacagaacg
6841 ccagagcaat gccggagata agcggcggaa tgttgaaggc gaaatggagc gcgcgtgaga
6901 cggcattcgc ctgcacgcta ttaaaaatca acccgtaggc gacgagcaga aagagggcga
6961 aaaccacgcc catccagcgc attcccagcc cacgcgccat ataccacgcc gggccgccgc
7021 ggaactggcc tgtcgggtca cgttctttat aaagctgggc aagcgaacac tcggcgaagg
7081 aggtcgccat gccaatgatg gccgagaccc acatccagaa taccgcgccg ggaccgcctg
7141 cggcgatagc cagcgccacg ccggccaggt taccgctgcc aatccgcgcc gcgaggctgg
7201 tacacagagc ctgaaatgac gtcaggccgc ctggctgcgg gctaaggctg cctttcagac
7261 tgcggctaaa ttggcgaata taacgaaact gaatgaatcc ggtacgccag gtaaaccaac
7321 atcctgcgcc gagcagcagg taaatcatta ccgagcccca gagtatttcg ttaataaaac
7381 tgaaaaactc aggcattaac gtccctcttg ttgatgccgg cacgctttga taatcctgta
7441 taagcgtgac ccatgatgta gatgaccttg tcagactaat attaacggca gtttaccata
7501 aatacggtgg tatcctttaa ttgcgcatca accgtcggca gatacgcaaa cagtgcacaa
7561 gggcagccag gtgcatgtag gcggttgcgc tgtgagtgcg tcgtgttatc atcagggtag
7621 accggttaca tcccctaaca agctgtttaa agagaaactc tatcatgacg gacaaattga
7681 cctcccttcg tcagttcacc accgtagtgg ctgataccgg agatatcgcg gcaatgaaac
7741 tgtatcagcc gcaggatgct acaactaacc cttctctcat tcttaacgca gcgcaaatcc
7801 cggaatatcg taagctgatt gacgatgctg tcgcctgggc gaaacagcag agcagcgacc
7861 gcgcgcagca ggttgttgac gcgaccgata agctggcggt gaatattggc ctggagatcc
7921 tgaagctggt gccggggcgt atttctaccg aagttgacgc gcgtctgtct tatgacactg
7981 aagcgtctat cgccaaagca aaacgtatca ttaaactcta caatgatgcg ggtatcagca
8041 acgatcgtat cctgatcaag ctggcgtcca cctggcaggg cattcgtgca gccgaacagc
8101 tggaaaaaga aggcatcaac tgtaacctga cgctgctgtt ctccttcgcg caggcgcgtg
8161 cgtgcgccga agcgggcgtc tacctgatct cgccgttcgt aggtcgtatt cttgactggt
8221 ataaagccaa taccgacaag aaagactatg cgccagctga agatccgggc gtggtttccg
8281 taacggaaat ctacgagtac tacaaacagc atggttacga aaccgtcgtt atgggcgcaa
8341 gcttccgtaa cgtaggcgaa attctggagc tggcgggctg cgaccgtctg actatcgcgc
8401 cggcattgct gaaagaactg gcggaaagcg aaggggcgat tgagcgtaag ctctctttct
8461 ccggcgaagt caaagcgcgc ccggaacgca ttaccgaagc cgagttcctg tggcagcatc
8521 accaggaccc catggcggtt gacaaactgg cggatggtat ccgtaagttt gcggtagacc
8581 aggaaaaact ggaaaaaatg atcggcgatc tgctgtaatc attaacgcgt ggccctgata
8641 tgggtcacgc tacctcttct gaaacctgtc tgtccttccc ttcgcagtgt atcattctgt
8701 ttaacgagac tgtttaaacg gaataatcat ggatacctta cgtattggct tagtttctat
8761 ctccgaccgc gcttcaagcg gcgtttacca ggataaaggc attcctgcgc ttgaggagtg
8821 gctcgcttct gcgctgacca cgcctttcga ggtccaacgg cgcttaattc ctgatgaaca
8881 ggaaattatc gagcaaacgt tgtgtgaact ggtcgatgag atgagctgtc atctggtgct
8941 gaccactggc ggtaccggtc cggcgcgtcg cgacgtcacg ccggacgcga cccttgccat
9001 cgccgaccgt gaaatgccag gttttggcga gcagatgcgc cagatcagcc tgcgctttgt
9061 gccgaccgcc attctttccc gccaggtggg cgttatccgt aaacaggcgt taattcttaa
9121 tctgcctgga cagccaaaat cgatcaaaga aacgctggaa ggcgtaaaag cggacgatgg
9181 cagcgttagc gtgccgggca tttttgcgag cgtgccgtat tgcatacagc tgcttgacgg
9241 gccgtatgtc gaaaccgcgc cggaagtggt tgccgctttc cgtccaaaga gcgccagacg
9301 tgagaatatg tcggactgac cggaaaatac tgatagtagg gttattcctc ccggtgcggg
9361 aggaataaaa gagatttagt gcgcctcgcc gattggcaga atagtgcggc caaattgctc
9421 gtttagcact tcacccatcg ccagataaat agcgctggcg ccgcaaacca gaccaaccca
9481 gcctgcgata tggatagttg cttcgttacc ggtgatattg ccgaccgcca gcagagcgaa
9541 cagtacggtc aggctcagga aaacaaattg cagcgcgcgg gcggctttca gcgtaccgaa
9601 gaacataaac agcgtgaaca cgccccacag acctaaataa gcgccgagta gctgagcgtc
9661 aggcgcatcc gtcagaccca ttttcggcat cagcaggata gcgaccagcg tcagccagaa
9721 cgaaccgtaa gaggtaaagg ccgttaaacc aaaggtattg ccttttttgt actccagcag
9781 accggcaaaa atttgcgcga taccgccgta gaaaatcccc atcgccagaa taataccgtc
9841 cagggcgaaa aaaccggcat tgtgcaggtt aagcagaatg gtggtcatgc cgaagcccat
9901 caggcccagc ggtgccggat tagccaactt agtgttgccc ataattcctc aaaatcatca
9961 taattgaatg gtgaaatagt ttcccagaat aacgagttcc gtattcgggg cgcggcataa
//
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