1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
|
.. highlight:: rest
.. _cross_linkers_module:
The :mod:`ihm.cross_linkers` Python module
==========================================
.. automodule:: ihm.cross_linkers
.. data:: dss
DSS cross-linker that links a primary amine with another primary amine
(non-water-soluble).
.. data:: dsg
DSG cross-linker that links a primary amine with another primary amine
(non-water-soluble).
.. data:: bs3
BS3 cross-linker that links a primary amine with another primary amine
(water-soluble).
.. data:: dsso
DSSO cross-linker that links a primary amine with another primary amine
(non-water-soluble). It is similar to DSS but can be cleaved in the gas
phase using collision-induced dissociation.
.. data:: edc
EDC cross-linker that links a carboxyl group with a primary amine.
.. data:: dhso
DHSO (dihydrazide sulfoxide) MS-cleavable cross-linker that links
carboxyl groups, described in
`Gutierrez et al, 2016 <https://dx.doi.org/10.1021/acs.analchem.6b02240>`_.
.. data:: bmso
BMSO (bismaleimide sulfoxide) MS-cleavable cross-linker that links
cysteines, described in
`Gutierrez et al, 2018 <https://dx.doi.org/10.1021/acs.analchem.8b01287>`_.
.. data:: sda
SDA (NHS-Diazirine) (succinimidyl 4,4′-azipentanoate) cross-linker that
links primary amines with nearly any other functional group via
long-wave UV-light activation.
.. data:: photo_leucine
L-photo-leucine. Non-canonical amino acid incorporated at leucine
positions that links leucine to any other functional group via long-wave
UV-light activation.
See `Suchanek et al, 2005 <https://doi.org/10.1038/nmeth752>`_.
.. data:: dsbu
dsbu (disuccinimidyl dibutyric urea) cross-linker that links a primary
amine with another primary amine (non-water-soluble).
Cleavable in the gas phase using collision-induced dissociation.
See `Müller et al, 2011 <https://doi.org/10.1021/ac101241t>`_.
.. data:: phoX
PhoX cross-linker that links a primary amine with another primary amine.
The spacer group contains a phosphonate group, making the cross-linker
IMAC-enrichable. Also known by the name DSPP. See
`Steigenberger et al, 2019 <https://doi.org/10.1021/acscentsci.9b00416>`_.
.. data:: tbuphoX
Tert-butyl PhoX cross-linker. Similar to PhoX, but containing a tert-butyl
group that renders the cross-linker cell permeable.
See `Jiang et al, 2021 <https://doi.org/10.1002/anie.202113937>`_.
|
