File: evoked.py

package info (click to toggle)
python-mne 0.8.6%2Bdfsg-2
  • links: PTS, VCS
  • area: main
  • in suites: jessie, jessie-kfreebsd
  • size: 87,892 kB
  • ctags: 6,639
  • sloc: python: 54,697; makefile: 165; sh: 15
file content (1232 lines) | stat: -rw-r--r-- 47,471 bytes parent folder | download
1
2
3
4
5
6
7
8
9
10
11
12
13
14
15
16
17
18
19
20
21
22
23
24
25
26
27
28
29
30
31
32
33
34
35
36
37
38
39
40
41
42
43
44
45
46
47
48
49
50
51
52
53
54
55
56
57
58
59
60
61
62
63
64
65
66
67
68
69
70
71
72
73
74
75
76
77
78
79
80
81
82
83
84
85
86
87
88
89
90
91
92
93
94
95
96
97
98
99
100
101
102
103
104
105
106
107
108
109
110
111
112
113
114
115
116
117
118
119
120
121
122
123
124
125
126
127
128
129
130
131
132
133
134
135
136
137
138
139
140
141
142
143
144
145
146
147
148
149
150
151
152
153
154
155
156
157
158
159
160
161
162
163
164
165
166
167
168
169
170
171
172
173
174
175
176
177
178
179
180
181
182
183
184
185
186
187
188
189
190
191
192
193
194
195
196
197
198
199
200
201
202
203
204
205
206
207
208
209
210
211
212
213
214
215
216
217
218
219
220
221
222
223
224
225
226
227
228
229
230
231
232
233
234
235
236
237
238
239
240
241
242
243
244
245
246
247
248
249
250
251
252
253
254
255
256
257
258
259
260
261
262
263
264
265
266
267
268
269
270
271
272
273
274
275
276
277
278
279
280
281
282
283
284
285
286
287
288
289
290
291
292
293
294
295
296
297
298
299
300
301
302
303
304
305
306
307
308
309
310
311
312
313
314
315
316
317
318
319
320
321
322
323
324
325
326
327
328
329
330
331
332
333
334
335
336
337
338
339
340
341
342
343
344
345
346
347
348
349
350
351
352
353
354
355
356
357
358
359
360
361
362
363
364
365
366
367
368
369
370
371
372
373
374
375
376
377
378
379
380
381
382
383
384
385
386
387
388
389
390
391
392
393
394
395
396
397
398
399
400
401
402
403
404
405
406
407
408
409
410
411
412
413
414
415
416
417
418
419
420
421
422
423
424
425
426
427
428
429
430
431
432
433
434
435
436
437
438
439
440
441
442
443
444
445
446
447
448
449
450
451
452
453
454
455
456
457
458
459
460
461
462
463
464
465
466
467
468
469
470
471
472
473
474
475
476
477
478
479
480
481
482
483
484
485
486
487
488
489
490
491
492
493
494
495
496
497
498
499
500
501
502
503
504
505
506
507
508
509
510
511
512
513
514
515
516
517
518
519
520
521
522
523
524
525
526
527
528
529
530
531
532
533
534
535
536
537
538
539
540
541
542
543
544
545
546
547
548
549
550
551
552
553
554
555
556
557
558
559
560
561
562
563
564
565
566
567
568
569
570
571
572
573
574
575
576
577
578
579
580
581
582
583
584
585
586
587
588
589
590
591
592
593
594
595
596
597
598
599
600
601
602
603
604
605
606
607
608
609
610
611
612
613
614
615
616
617
618
619
620
621
622
623
624
625
626
627
628
629
630
631
632
633
634
635
636
637
638
639
640
641
642
643
644
645
646
647
648
649
650
651
652
653
654
655
656
657
658
659
660
661
662
663
664
665
666
667
668
669
670
671
672
673
674
675
676
677
678
679
680
681
682
683
684
685
686
687
688
689
690
691
692
693
694
695
696
697
698
699
700
701
702
703
704
705
706
707
708
709
710
711
712
713
714
715
716
717
718
719
720
721
722
723
724
725
726
727
728
729
730
731
732
733
734
735
736
737
738
739
740
741
742
743
744
745
746
747
748
749
750
751
752
753
754
755
756
757
758
759
760
761
762
763
764
765
766
767
768
769
770
771
772
773
774
775
776
777
778
779
780
781
782
783
784
785
786
787
788
789
790
791
792
793
794
795
796
797
798
799
800
801
802
803
804
805
806
807
808
809
810
811
812
813
814
815
816
817
818
819
820
821
822
823
824
825
826
827
828
829
830
831
832
833
834
835
836
837
838
839
840
841
842
843
844
845
846
847
848
849
850
851
852
853
854
855
856
857
858
859
860
861
862
863
864
865
866
867
868
869
870
871
872
873
874
875
876
877
878
879
880
881
882
883
884
885
886
887
888
889
890
891
892
893
894
895
896
897
898
899
900
901
902
903
904
905
906
907
908
909
910
911
912
913
914
915
916
917
918
919
920
921
922
923
924
925
926
927
928
929
930
931
932
933
934
935
936
937
938
939
940
941
942
943
944
945
946
947
948
949
950
951
952
953
954
955
956
957
958
959
960
961
962
963
964
965
966
967
968
969
970
971
972
973
974
975
976
977
978
979
980
981
982
983
984
985
986
987
988
989
990
991
992
993
994
995
996
997
998
999
1000
1001
1002
1003
1004
1005
1006
1007
1008
1009
1010
1011
1012
1013
1014
1015
1016
1017
1018
1019
1020
1021
1022
1023
1024
1025
1026
1027
1028
1029
1030
1031
1032
1033
1034
1035
1036
1037
1038
1039
1040
1041
1042
1043
1044
1045
1046
1047
1048
1049
1050
1051
1052
1053
1054
1055
1056
1057
1058
1059
1060
1061
1062
1063
1064
1065
1066
1067
1068
1069
1070
1071
1072
1073
1074
1075
1076
1077
1078
1079
1080
1081
1082
1083
1084
1085
1086
1087
1088
1089
1090
1091
1092
1093
1094
1095
1096
1097
1098
1099
1100
1101
1102
1103
1104
1105
1106
1107
1108
1109
1110
1111
1112
1113
1114
1115
1116
1117
1118
1119
1120
1121
1122
1123
1124
1125
1126
1127
1128
1129
1130
1131
1132
1133
1134
1135
1136
1137
1138
1139
1140
1141
1142
1143
1144
1145
1146
1147
1148
1149
1150
1151
1152
1153
1154
1155
1156
1157
1158
1159
1160
1161
1162
1163
1164
1165
1166
1167
1168
1169
1170
1171
1172
1173
1174
1175
1176
1177
1178
1179
1180
1181
1182
1183
1184
1185
1186
1187
1188
1189
1190
1191
1192
1193
1194
1195
1196
1197
1198
1199
1200
1201
1202
1203
1204
1205
1206
1207
1208
1209
1210
1211
1212
1213
1214
1215
1216
1217
1218
1219
1220
1221
1222
1223
1224
1225
1226
1227
1228
1229
1230
1231
1232
# Authors: Alexandre Gramfort <alexandre.gramfort@telecom-paristech.fr>
#          Matti Hamalainen <msh@nmr.mgh.harvard.edu>
#          Denis Engemann <denis.engemann@gmail.com>
#          Andrew Dykstra <andrew.r.dykstra@gmail.com>
#
# License: BSD (3-clause)

from copy import deepcopy
import numpy as np
import warnings

from .baseline import rescale
from .channels import ContainsMixin, PickDropChannelsMixin
from .filter import resample, detrend
from .fixes import in1d
from .utils import (_check_pandas_installed, check_fname, logger, verbose,
                    deprecated, object_hash)
from .viz import plot_evoked, plot_evoked_topomap, _mutable_defaults
from .viz import plot_evoked_field
from .viz import plot_evoked_image
from .externals.six import string_types

from .io.constants import FIFF
from .io.open import fiff_open
from .io.tag import read_tag
from .io.tree import dir_tree_find
from .io.pick import channel_type, pick_types
from .io.meas_info import read_meas_info, write_meas_info
from .io.proj import ProjMixin
from .io.write import (start_file, start_block, end_file, end_block,
                       write_int, write_string, write_float_matrix,
                       write_id)

aspect_dict = {'average': FIFF.FIFFV_ASPECT_AVERAGE,
               'standard_error': FIFF.FIFFV_ASPECT_STD_ERR}
aspect_rev = {str(FIFF.FIFFV_ASPECT_AVERAGE): 'average',
              str(FIFF.FIFFV_ASPECT_STD_ERR): 'standard_error'}


class Evoked(ProjMixin, ContainsMixin, PickDropChannelsMixin):
    """Evoked data

    Parameters
    ----------
    fname : string
        Name of evoked/average FIF file to load.
        If None no data is loaded.
    condition : int, or str
        Dataset ID number (int) or comment/name (str). Optional if there is
        only one data set in file.
    baseline : tuple or list of length 2, or None
        The time interval to apply rescaling / baseline correction.
        If None do not apply it. If baseline is (a, b)
        the interval is between "a (s)" and "b (s)".
        If a is None the beginning of the data is used
        and if b is None then b is set to the end of the interval.
        If baseline is equal ot (None, None) all the time
        interval is used. If None, no correction is applied.
    proj : bool, optional
        Apply SSP projection vectors
    kind : str
        Either 'average' or 'standard_error'. The type of data to read.
        Only used if 'condition' is a str.
    verbose : bool, str, int, or None
        If not None, override default verbose level (see mne.verbose).

    Attributes
    ----------
    info : dict
        Measurement info.
    ch_names : list of string
        List of channels' names.
    nave : int
        Number of averaged epochs.
    kind : str
        Type of data, either average or standard_error.
    first : int
        First time sample.
    last : int
        Last time sample.
    comment : string
        Comment on dataset. Can be the condition.
    times : array
        Array of time instants in seconds.
    data : array of shape (n_channels, n_times)
        Evoked response.
    verbose : bool, str, int, or None.
        See above.
    """
    @verbose
    def __init__(self, fname, condition=None, baseline=None, proj=True,
                 kind='average', verbose=None, setno=None):

        if fname is None:
            raise ValueError('No evoked filename specified')

        if condition is None and setno is not None:
            condition = setno
            msg = ("'setno' will be deprecated in 0.9. Use 'condition' "
                   "instead.")
            warnings.warn(msg, DeprecationWarning)

        self.verbose = verbose
        logger.info('Reading %s ...' % fname)
        fid, tree, _ = fiff_open(fname)
        if not isinstance(proj, bool):
            raise ValueError(r"'proj' must be 'True' or 'False'")

        #   Read the measurement info
        info, meas = read_meas_info(fid, tree)
        info['filename'] = fname

        #   Locate the data of interest
        processed = dir_tree_find(meas, FIFF.FIFFB_PROCESSED_DATA)
        if len(processed) == 0:
            fid.close()
            raise ValueError('Could not find processed data')

        evoked_node = dir_tree_find(meas, FIFF.FIFFB_EVOKED)
        if len(evoked_node) == 0:
            fid.close()
            raise ValueError('Could not find evoked data')

        # find string-based entry
        if isinstance(condition, string_types):
            if not kind in aspect_dict.keys():
                fid.close()
                raise ValueError('kind must be "average" or '
                                 '"standard_error"')

            comments, aspect_kinds, t = _get_entries(fid, evoked_node)
            goods = np.logical_and(in1d(comments, [condition]),
                                   in1d(aspect_kinds, [aspect_dict[kind]]))
            found_cond = np.where(goods)[0]
            if len(found_cond) != 1:
                fid.close()
                raise ValueError('condition "%s" (%s) not found, out of found '
                                 'datasets:\n  %s' % (condition, kind, t))
            condition = found_cond[0]

        if condition >= len(evoked_node) or condition < 0:
            fid.close()
            raise ValueError('Data set selector out of range')

        my_evoked = evoked_node[condition]

        # Identify the aspects
        aspects = dir_tree_find(my_evoked, FIFF.FIFFB_ASPECT)
        if len(aspects) > 1:
            logger.info('Multiple aspects found. Taking first one.')
        my_aspect = aspects[0]

        # Now find the data in the evoked block
        nchan = 0
        sfreq = -1
        chs = []
        comment = None
        for k in range(my_evoked['nent']):
            my_kind = my_evoked['directory'][k].kind
            pos = my_evoked['directory'][k].pos
            if my_kind == FIFF.FIFF_COMMENT:
                tag = read_tag(fid, pos)
                comment = tag.data
            elif my_kind == FIFF.FIFF_FIRST_SAMPLE:
                tag = read_tag(fid, pos)
                first = int(tag.data)
            elif my_kind == FIFF.FIFF_LAST_SAMPLE:
                tag = read_tag(fid, pos)
                last = int(tag.data)
            elif my_kind == FIFF.FIFF_NCHAN:
                tag = read_tag(fid, pos)
                nchan = int(tag.data)
            elif my_kind == FIFF.FIFF_SFREQ:
                tag = read_tag(fid, pos)
                sfreq = float(tag.data)
            elif my_kind == FIFF.FIFF_CH_INFO:
                tag = read_tag(fid, pos)
                chs.append(tag.data)

        if comment is None:
            comment = 'No comment'

        #   Local channel information?
        if nchan > 0:
            if chs is None:
                fid.close()
                raise ValueError('Local channel information was not found '
                                 'when it was expected.')

            if len(chs) != nchan:
                fid.close()
                raise ValueError('Number of channels and number of '
                                 'channel definitions are different')

            info['chs'] = chs
            info['nchan'] = nchan
            logger.info('    Found channel information in evoked data. '
                        'nchan = %d' % nchan)
            if sfreq > 0:
                info['sfreq'] = sfreq

        nsamp = last - first + 1
        logger.info('    Found the data of interest:')
        logger.info('        t = %10.2f ... %10.2f ms (%s)'
                    % (1000 * first / info['sfreq'],
                       1000 * last / info['sfreq'], comment))
        if info['comps'] is not None:
            logger.info('        %d CTF compensation matrices available'
                        % len(info['comps']))

        # Read the data in the aspect block
        nave = 1
        epoch = []
        for k in range(my_aspect['nent']):
            kind = my_aspect['directory'][k].kind
            pos = my_aspect['directory'][k].pos
            if kind == FIFF.FIFF_COMMENT:
                tag = read_tag(fid, pos)
                comment = tag.data
            elif kind == FIFF.FIFF_ASPECT_KIND:
                tag = read_tag(fid, pos)
                aspect_kind = int(tag.data)
            elif kind == FIFF.FIFF_NAVE:
                tag = read_tag(fid, pos)
                nave = int(tag.data)
            elif kind == FIFF.FIFF_EPOCH:
                tag = read_tag(fid, pos)
                epoch.append(tag)

        logger.info('        nave = %d - aspect type = %d'
                    % (nave, aspect_kind))

        nepoch = len(epoch)
        if nepoch != 1 and nepoch != info['nchan']:
            fid.close()
            raise ValueError('Number of epoch tags is unreasonable '
                             '(nepoch = %d nchan = %d)'
                             % (nepoch, info['nchan']))

        if nepoch == 1:
            # Only one epoch
            all_data = epoch[0].data.astype(np.float)
            # May need a transpose if the number of channels is one
            if all_data.shape[1] == 1 and info['nchan'] == 1:
                all_data = all_data.T.astype(np.float)
        else:
            # Put the old style epochs together
            all_data = np.concatenate([e.data[None, :] for e in epoch],
                                      axis=0).astype(np.float)

        if all_data.shape[1] != nsamp:
            fid.close()
            raise ValueError('Incorrect number of samples (%d instead of %d)'
                             % (all_data.shape[1], nsamp))

        # Calibrate
        cals = np.array([info['chs'][k]['cal']
                         * info['chs'][k].get('scale', 1.0)
                         for k in range(info['nchan'])])
        all_data *= cals[:, np.newaxis]

        times = np.arange(first, last + 1, dtype=np.float) / info['sfreq']
        self.info = info

        # Put the rest together all together
        self.nave = nave
        self._aspect_kind = aspect_kind
        self.kind = aspect_rev.get(str(self._aspect_kind), 'Unknown')
        self.first = first
        self.last = last
        self.comment = comment
        self.times = times
        self.data = all_data

        # bind info, proj, data to self so apply_proj can be used
        self.data = all_data
        self.proj = False
        if proj:
            self.apply_proj()
        # Run baseline correction
        self.data = rescale(self.data, times, baseline, 'mean', copy=False)

        fid.close()

    def save(self, fname):
        """Save dataset to file.

        Parameters
        ----------
        fname : string
            Name of the file where to save the data.
        """
        write_evokeds(fname, self)

    def __repr__(self):
        s = "comment : '%s'" % self.comment
        s += ", time : [%f, %f]" % (self.times[0], self.times[-1])
        s += ", n_epochs : %d" % self.nave
        s += ", n_channels x n_times : %s x %s" % self.data.shape
        return "<Evoked  |  %s>" % s

    @property
    def ch_names(self):
        return self.info['ch_names']

    def crop(self, tmin=None, tmax=None):
        """Crop data to a given time interval
        """
        times = self.times
        mask = np.ones(len(times), dtype=np.bool)
        if tmin is not None:
            mask = mask & (times >= tmin)
        if tmax is not None:
            mask = mask & (times <= tmax)
        self.times = times[mask]
        self.first = int(self.times[0] * self.info['sfreq'])
        self.last = len(self.times) + self.first - 1
        self.data = self.data[:, mask]

    def shift_time(self, tshift, relative=True):
        """Shift time scale in evoked data

        Parameters
        ----------
        tshift : float
            The amount of time shift to be applied if relative is True
            else the first time point. When relative is True, positive value
            of tshift moves the data forward while negative tshift moves it
            backward.
        relative : bool
            If true, move the time backwards or forwards by specified amount.
            Else, set the starting time point to the value of tshift.

        Notes
        -----
        Maximum accuracy of time shift is 1 / evoked.info['sfreq']
        """
        times = self.times
        sfreq = self.info['sfreq']

        offset = self.first if relative else 0

        self.first = int(tshift * sfreq) + offset
        self.last = self.first + len(times) - 1
        self.times = np.arange(self.first, self.last + 1,
                               dtype=np.float) / sfreq

    def plot(self, picks=None, exclude='bads', unit=True, show=True, ylim=None,
             proj=False, xlim='tight', hline=None, units=None, scalings=None,
             titles=None, axes=None):
        """Plot evoked data as butterfly plots

        Note: If bad channels are not excluded they are shown in red.

        Parameters
        ----------
        picks : array-like of int | None
            The indices of channels to plot. If None show all.
        exclude : list of str | 'bads'
            Channels names to exclude from being shown. If 'bads', the
            bad channels are excluded.
        unit : bool
            Scale plot with channel (SI) unit.
        show : bool
            Call pyplot.show() at the end or not.
        ylim : dict
            ylim for plots. e.g. ylim = dict(eeg=[-200e-6, 200e6])
            Valid keys are eeg, mag, grad
        xlim : 'tight' | tuple | None
            xlim for plots.
        proj : bool | 'interactive'
            If true SSP projections are applied before display. If
            'interactive', a check box for reversible selection of SSP
            projection vectors will be shown.
        hline : list of floats | None
            The values at which show an horizontal line.
        units : dict | None
            The units of the channel types used for axes lables. If None,
            defaults to `dict(eeg='uV', grad='fT/cm', mag='fT')`.
        scalings : dict | None
            The scalings of the channel types to be applied for plotting.
            If None, defaults to `dict(eeg=1e6, grad=1e13, mag=1e15)`.
        titles : dict | None
            The titles associated with the channels. If None, defaults to
            `dict(eeg='EEG', grad='Gradiometers', mag='Magnetometers')`.
        axes : instance of Axes | list | None
            The axes to plot to. If list, the list must be a list of Axes of
            the same length as the number of channel types. If instance of
            Axes, there must be only one channel type plotted.
        """
        return plot_evoked(self, picks=picks, exclude=exclude, unit=unit,
                           show=show, ylim=ylim, proj=proj, xlim=xlim,
                           hline=hline, units=units, scalings=scalings,
                           titles=titles, axes=axes)

    def plot_image(self, picks=None, exclude='bads', unit=True, show=True,
                   clim=None, proj=False, xlim='tight', units=None,
                   scalings=None, titles=None, axes=None, cmap='RdBu_r'):
        """Plot evoked data as images

        Parameters
        ----------
        picks : array-like of int | None
            The indices of channels to plot. If None show all.
        exclude : list of str | 'bads'
            Channels names to exclude from being shown. If 'bads', the
            bad channels are excluded.
        unit : bool
            Scale plot with channel (SI) unit.
        show : bool
            Call pyplot.show() at the end or not.
        clim : dict
            clim for images. e.g. clim = dict(eeg=[-200e-6, 200e6])
            Valid keys are eeg, mag, grad
        xlim : 'tight' | tuple | None
            xlim for plots.
        proj : bool | 'interactive'
            If true SSP projections are applied before display. If
            'interactive', a check box for reversible selection of SSP
            projection vectors will be shown.
        units : dict | None
            The units of the channel types used for axes lables. If None,
            defaults to `dict(eeg='uV', grad='fT/cm', mag='fT')`.
        scalings : dict | None
            The scalings of the channel types to be applied for plotting.
            If None, defaults to `dict(eeg=1e6, grad=1e13, mag=1e15)`.
        titles : dict | None
            The titles associated with the channels. If None, defaults to
            `dict(eeg='EEG', grad='Gradiometers', mag='Magnetometers')`.
        axes : instance of Axes | list | None
            The axes to plot to. If list, the list must be a list of Axes of
            the same length as the number of channel types. If instance of
            Axes, there must be only one channel type plotted.
        cmap : matplotlib colormap
            Colormap.
        """
        return plot_evoked_image(self, picks=picks, exclude=exclude, unit=unit,
                                 show=show, clim=clim, proj=proj, xlim=xlim,
                                 units=units, scalings=scalings,
                                 titles=titles, axes=axes, cmap=cmap)

    def plot_topomap(self, times=None, ch_type='mag', layout=None, vmin=None,
                     vmax=None, cmap='RdBu_r', sensors='k,', colorbar=True,
                     scale=None, scale_time=1e3, unit=None, res=64, size=1,
                     format="%3.1f", time_format='%01d ms', proj=False,
                     show=True, show_names=False, title=None, mask=None,
                     mask_params=None, outlines='head', contours=6,
                     image_interp='bilinear'):
        """Plot topographic maps of specific time points

        Parameters
        ----------
        times : float | array of floats | None.
            The time point(s) to plot. If None, 10 topographies will be shown
            will a regular time spacing between the first and last time
            instant.
        ch_type : 'mag' | 'grad' | 'planar1' | 'planar2' | 'eeg'
            The channel type to plot. For 'grad', the gradiometers are collec-
            ted in pairs and the RMS for each pair is plotted.
        layout : None | Layout
            Layout instance specifying sensor positions (does not need to
            be specified for Neuromag data). If possible, the correct
            layout file is inferred from the data; if no appropriate layout
            file was found, the layout is automatically generated from the
            sensor locations.
        vmin : float | callable
            The value specfying the lower bound of the color range.
            If None, and vmax is None, -vmax is used. Else np.min(data).
            If callable, the output equals vmin(data).
        vmax : float | callable
            The value specfying the upper bound of the color range.
            If None, the maximum absolute value is used. If vmin is None,
            but vmax is not, defaults to np.min(data).
            If callable, the output equals vmax(data).
        cmap : matplotlib colormap
            Colormap. Defaults to 'RdBu_r'
        sensors : bool | str
            Add markers for sensor locations to the plot. Accepts matplotlib
            plot format string (e.g., 'r+' for red plusses).
        colorbar : bool
            Plot a colorbar.
        scale : float | None
            Scale the data for plotting. If None, defaults to 1e6 for eeg, 1e13
            for grad and 1e15 for mag.
        scale_time : float | None
            Scale the time labels. Defaults to 1e3 (ms).
        units : str | None
            The units of the channel types used for colorbar lables. If
            scale == None the unit is automatically determined.
        res : int
            The resolution of the topomap image (n pixels along each side).
        size : scalar
            Side length of the topomaps in inches (only applies when plotting
            multiple topomaps at a time).
        format : str
            String format for colorbar values.
        time_format : str
            String format for topomap values. Defaults to "%01d ms"
        proj : bool | 'interactive'
            If true SSP projections are applied before display. If
            'interactive', a check box for reversible selection of SSP
            projection vectors will be shown.
        show : bool
            Call pyplot.show() at the end.
        show_names : bool | callable
            If True, show channel names on top of the map. If a callable is
            passed, channel names will be formatted using the callable; e.g.,
            to delete the prefix 'MEG ' from all channel names, pass the
            function
            lambda x: x.replace('MEG ', ''). If `mask` is not None, only
            significant sensors will be shown.
        title : str | None
            Title. If None (default), no title is displayed.
        mask : ndarray of bool, shape (n_channels, n_times) | None
            The channels to be marked as significant at a given time point.
            Indicies set to `True` will be considered. Defaults to None.
        mask_params : dict | None
            Additional plotting parameters for plotting significant sensors.
            Default (None) equals:
            dict(marker='o', markerfacecolor='w', markeredgecolor='k',
                 linewidth=0, markersize=4)
        outlines : 'head' | dict | None
            The outlines to be drawn. If 'head', a head scheme will be drawn.
            If dict, each key refers to a tuple of x and y positions. The
            values in 'mask_pos' will serve as image mask. If None,
            nothing will be drawn. Defaults to 'head'.
        image_interp : str
            The image interpolation to be used. All matplotlib options are
            accepted.

        """
        return plot_evoked_topomap(self, times=times, ch_type=ch_type,
                                   layout=layout, vmin=vmin,
                                   vmax=vmax, cmap=cmap, sensors=sensors,
                                   colorbar=colorbar, scale=scale,
                                   scale_time=scale_time,
                                   unit=unit, res=res, proj=proj, size=size,
                                   format=format, time_format=time_format,
                                   show=show, show_names=show_names,
                                   title=title, mask=mask,
                                   mask_params=mask_params,
                                   outlines=outlines, contours=contours,
                                   image_interp=image_interp)

    def plot_field(self, surf_maps, time=None, time_label='t = %0.0f ms',
                   n_jobs=1):
        """Plot MEG/EEG fields on head surface and helmet in 3D

        Parameters
        ----------
        surf_maps : list
            The surface mapping information obtained with make_field_map.
        time : float | None
            The time point at which the field map shall be displayed. If None,
            the average peak latency (across sensor types) is used.
        time_label : str
            How to print info about the time instant visualized.
        n_jobs : int
            Number of jobs to run in parallel.

        Returns
        -------
        fig : instance of mlab.Figure
            The mayavi figure.
        """
        return plot_evoked_field(self, surf_maps, time=time,
                                 time_label=time_label, n_jobs=n_jobs)

    def to_nitime(self, picks=None):
        """Export Evoked object to NiTime

        Parameters
        ----------
        picks : array-like of int | None
            Indices of channels to apply. If None, all channels will be
            exported.

        Returns
        -------
        evoked_ts : instance of nitime.TimeSeries
            The TimeSeries instance
        """
        try:
            from nitime import TimeSeries  # to avoid strong dependency
        except ImportError:
            raise Exception('the nitime package is missing')

        evoked_ts = TimeSeries(self.data if picks is None
                               else self.data[picks],
                               sampling_rate=self.info['sfreq'])
        return evoked_ts

    def as_data_frame(self, picks=None, scale_time=1e3, scalings=None,
                      use_time_index=True, copy=True):
        """Get the Evoked object as a Pandas DataFrame

        Export data in tabular structure: each row corresponds to a time point,
        and each column to a channel.

        Parameters
        ----------
        picks : array-like of int | None
            If None all channels are kept, otherwise the channels indices in
            picks are kept.
        scale_time : float
            Scaling to be applied to time units.
        scalings : dict | None
            Scaling to be applied to the channels picked. If None, defaults to
            ``scalings=dict(eeg=1e6, grad=1e13, mag=1e15, misc=1.0)`.
        use_time_index : bool
            If False, times will be included as in the data table, else it will
            be used as index object.
        copy : bool
            If true, evoked will be copied. Else data may be modified in place.

        Returns
        -------
        df : instance of pandas.core.DataFrame
            Evoked data exported into tabular data structure.
        """

        pd = _check_pandas_installed()

        if picks is None:
            picks = list(range(self.info['nchan']))
        else:
            if not in1d(picks, np.arange(len(self.ch_names))).all():
                raise ValueError('At least one picked channel is not present '
                                 'in this Evoked instance.')

        data, times = self.data, self.times

        if copy is True:
            data = data.copy()

        types = [channel_type(self.info, idx) for idx in picks]
        n_channel_types = 0
        ch_types_used = []

        scalings = _mutable_defaults(('scalings', scalings))[0]
        for t in scalings.keys():
            if t in types:
                n_channel_types += 1
                ch_types_used.append(t)

        for t in ch_types_used:
            scaling = scalings[t]
            idx = [picks[i] for i in range(len(picks)) if types[i] == t]
            if len(idx) > 0:
                data[idx] *= scaling

        assert times.shape[0] == data.shape[1]
        col_names = [self.ch_names[k] for k in picks]

        df = pd.DataFrame(data.T, columns=col_names)
        df.insert(0, 'time', times * scale_time)

        if use_time_index is True:
            if 'time' in df:
                df['time'] = df['time'].astype(np.int64)
            with warnings.catch_warnings(record=True):
                df.set_index('time', inplace=True)

        return df

    def resample(self, sfreq, npad=100, window='boxcar'):
        """Resample data

        This function operates in-place.

        Parameters
        ----------
        sfreq : float
            New sample rate to use
        npad : int
            Amount to pad the start and end of the data.
        window : string or tuple
            Window to use in resampling. See scipy.signal.resample.
        """
        o_sfreq = self.info['sfreq']
        self.data = resample(self.data, sfreq, o_sfreq, npad, -1, window)
        # adjust indirectly affected variables
        self.info['sfreq'] = sfreq
        self.times = (np.arange(self.data.shape[1], dtype=np.float) / sfreq
                      + self.times[0])
        self.first = int(self.times[0] * self.info['sfreq'])
        self.last = len(self.times) + self.first - 1

    def detrend(self, order=1, picks=None):
        """Detrend data

        This function operates in-place.

        Parameters
        ----------
        order : int
            Either 0 or 1, the order of the detrending. 0 is a constant
            (DC) detrend, 1 is a linear detrend.
        picks : array-like of int | None
            If None only MEG and EEG channels are detrended.
        """
        if picks is None:
            picks = pick_types(self.info, meg=True, eeg=True, ref_meg=False,
                               stim=False, eog=False, ecg=False, emg=False,
                               exclude='bads')
        self.data[picks] = detrend(self.data[picks], order, axis=-1)

    def copy(self):
        """Copy the instance of evoked

        Returns
        -------
        evoked : instance of Evoked
        """
        evoked = deepcopy(self)
        return evoked

    def __add__(self, evoked):
        """Add evoked taking into account number of epochs"""
        out = merge_evoked([self, evoked])
        out.comment = self.comment + " + " + evoked.comment
        return out

    def __sub__(self, evoked):
        """Add evoked taking into account number of epochs"""
        this_evoked = deepcopy(evoked)
        this_evoked.data *= -1.
        out = merge_evoked([self, this_evoked])
        out.comment = self.comment + " - " + this_evoked.comment
        return out

    def __hash__(self):
        return object_hash(dict(info=self.info, data=self.data))

    def get_peak(self, ch_type=None, tmin=None, tmax=None, mode='abs',
                 time_as_index=False):
        """Get location and latency of peak amplitude

        Parameters
        ----------
        ch_type : {'mag', 'grad', 'eeg', 'misc', None}
            The channel type to use. Defaults to None. If more than one sensor
            Type is present in the data the channel type has to be explicitly
            set.
        tmin : float | None
            The minimum point in time to be considered for peak getting.
        tmax : float | None
            The maximum point in time to be considered for peak getting.
        mode : {'pos', 'neg', 'abs'}
            How to deal with the sign of the data. If 'pos' only positive
            values will be considered. If 'neg' only negative values will
            be considered. If 'abs' absolute values will be considered.
            Defaults to 'abs'.
        time_as_index : bool
            Whether to return the time index instead of the latency in seconds.

        Returns
        -------
        ch_name : str
            The channel exhibiting the maximum response.
        latency : float | int
            The time point of the maximum response, either latency in seconds
            or index.
        """
        supported = ('mag', 'grad', 'eeg', 'misc', 'None')

        data_picks = pick_types(self.info, meg=True, eeg=True, ref_meg=False)
        types_used = set([channel_type(self.info, idx) for idx in data_picks])

        if str(ch_type) not in supported:
            raise ValueError('Channel type must be `{supported}`. You gave me '
                             '`{ch_type}` instead.'
                             .format(ch_type=ch_type,
                                     supported='` or `'.join(supported)))

        elif ch_type is not None and ch_type not in types_used:
            raise ValueError('Channel type `{ch_type}` not found in this '
                             'evoked object.'
                              .format(ch_type=ch_type))

        elif len(types_used) > 1 and ch_type is None:
            raise RuntimeError('More than one sensor type found. `ch_type` '
                               'must not be `None`, pass a sensor type '
                               'value instead')

        meg, eeg, misc, picks = False, False, False, None

        if ch_type == 'mag':
            meg = ch_type
        elif ch_type == 'grad':
            meg = ch_type
        elif ch_type == 'eeg':
            eeg = True
        elif ch_type == 'misc':
            misc = True

        if ch_type is not None:
            picks = pick_types(self.info, meg=meg, eeg=eeg, misc=misc,
                               ref_meg=False)

        data = self.data if picks is None else self.data[picks]
        ch_idx, time_idx = _get_peak(data, self.times, tmin,
                                     tmax, mode)

        return (self.ch_names[ch_idx],
                time_idx if time_as_index else self.times[time_idx])


class EvokedArray(Evoked):
    """Evoked object from numpy array

    Parameters
    ----------
    data : array of shape (n_channels, n_times)
        The channels' evoked response.
    info : instance of Info
        Info dictionary. Consider using ``create_info`` to populate
        this structure.
    tmin : float
        Start time before event.
    comment : string
        Comment on dataset. Can be the condition. Defaults to ''.
    nave : int
        Number of averaged epochs. Defaults to 1.
    kind : str
        Type of data, either average or standard_error. Defaults to 'average'.
    verbose : bool, str, int, or None
        If not None, override default verbose level (see mne.verbose).
        Defaults to raw.verbose.
    """

    @verbose
    def __init__(self, data, info, tmin, comment='', nave=1, kind='average',
                 verbose=None):

        dtype = np.complex128 if np.any(np.iscomplex(data)) else np.float64
        data = np.asanyarray(data, dtype=dtype)

        if data.ndim != 2:
            raise ValueError('Data must be a 2D array of shape (n_channels, '
                             'n_samples)')

        if len(info['ch_names']) != np.shape(data)[0]:
            raise ValueError('Info and data must have same number of '
                             'channels.')

        self.data = data

        # XXX: this should use round and be tested
        self.first = int(tmin * info['sfreq'])
        self.last = self.first + np.shape(data)[-1] - 1
        self.times = np.arange(self.first, self.last + 1, dtype=np.float)
        self.times /= info['sfreq']

        self.info = info
        self.nave = nave
        self.kind = kind
        self.comment = comment
        self.proj = None
        self.picks = None
        self.verbose = verbose
        self._projector = None
        if self.kind == 'average':
            self._aspect_kind = aspect_dict['average']
        else:
            self._aspect_kind = aspect_dict['standard_error']


def _get_entries(fid, evoked_node):
    """Helper to get all evoked entries"""
    comments = list()
    aspect_kinds = list()
    for ev in evoked_node:
        for k in range(ev['nent']):
            my_kind = ev['directory'][k].kind
            pos = ev['directory'][k].pos
            if my_kind == FIFF.FIFF_COMMENT:
                tag = read_tag(fid, pos)
                comments.append(tag.data)
        my_aspect = dir_tree_find(ev, FIFF.FIFFB_ASPECT)[0]
        for k in range(my_aspect['nent']):
            my_kind = my_aspect['directory'][k].kind
            pos = my_aspect['directory'][k].pos
            if my_kind == FIFF.FIFF_ASPECT_KIND:
                tag = read_tag(fid, pos)
                aspect_kinds.append(int(tag.data))
    comments = np.atleast_1d(comments)
    aspect_kinds = np.atleast_1d(aspect_kinds)
    if len(comments) != len(aspect_kinds) or len(comments) == 0:
        fid.close()
        raise ValueError('Dataset names in FIF file '
                         'could not be found.')
    t = [aspect_rev.get(str(a), 'Unknown') for a in aspect_kinds]
    t = ['"' + c + '" (' + tt + ')' for tt, c in zip(t, comments)]
    t = '  ' + '\n  '.join(t)
    return comments, aspect_kinds, t


def _get_evoked_node(fname):
    """Helper to get info in evoked file"""
    f, tree, _ = fiff_open(fname)
    with f as fid:
        _, meas = read_meas_info(fid, tree)
        evoked_node = dir_tree_find(meas, FIFF.FIFFB_EVOKED)
    return evoked_node


def merge_evoked(all_evoked):
    """Merge/concat evoked data

    Data should have the same channels and the same time instants.

    Parameters
    ----------
    all_evoked : list of Evoked
        The evoked datasets

    Returns
    -------
    evoked : Evoked
        The merged evoked data
    """
    evoked = deepcopy(all_evoked[0])

    ch_names = evoked.ch_names
    for e in all_evoked[1:]:
        assert e.ch_names == ch_names, ValueError("%s and %s do not contain "
                                                  "the same channels"
                                                  % (evoked, e))
        assert np.max(np.abs(e.times - evoked.times)) < 1e-7, \
            ValueError("%s and %s do not contain the same time "
                       "instants" % (evoked, e))

    # use union of bad channels
    bads = list(set(evoked.info['bads']).union(*(ev.info['bads']
                                                 for ev in all_evoked[1:])))
    evoked.info['bads'] = bads

    all_nave = sum(e.nave for e in all_evoked)
    evoked.data = sum(e.nave * e.data for e in all_evoked) / all_nave
    evoked.nave = all_nave
    return evoked


@deprecated("'read_evoked' will be removed in v0.9. Use 'read_evokeds.'")
def read_evoked(fname, setno=None, baseline=None, kind='average', proj=True):
    """Read an evoked dataset

    Parameters
    ----------
    fname : string
        The file name.
    setno : int or str | list of int or str | None
        The index or list of indices of the evoked dataset to read. FIF files
        can contain multiple datasets. If None and there is only one dataset in
        the file, this dataset is loaded.
    baseline : None (default) or tuple of length 2
        The time interval to apply baseline correction. If None do not apply it.
        If baseline is (a, b) the interval is between "a (s)" and "b (s)". If a
        is None the beginning of the data is used and if b is None then b is set
        to the end of the interval. If baseline is equal ot (None, None) all the
        time interval is used.
    kind : str
        Either 'average' or 'standard_error', the type of data to read.
    proj : bool
        If False, available projectors won't be applied to the data.

    Returns
    -------
    evoked : instance of Evoked or list of Evoked
        The evoked datasets.
    """
    evoked_node = _get_evoked_node(fname)
    if setno is None and len(evoked_node) > 1:
        fid, _, _ = fiff_open(fname)
        try:
            _, _, t = _get_entries(fid, evoked_node)
        except:
            t = 'None found, must use integer'
        else:
            fid.close()
        raise ValueError('%d datasets present, setno parameter must be set.'
                         'Candidate setno names:\n%s' % (len(evoked_node), t))
    elif isinstance(setno, list):
        return [Evoked(fname, s, baseline=baseline, kind=kind, proj=proj)
                for s in setno]
    else:
        if setno is None:
            setno = 0
        return Evoked(fname, setno, baseline=baseline, kind=kind, proj=proj)


@verbose
def read_evokeds(fname, condition=None, baseline=None, kind='average',
                 proj=True, verbose=None):
    """Read evoked dataset(s)

    Parameters
    ----------
    fname : string
        The file name, which should end with -ave.fif or -ave.fif.gz.
    condition : int or str | list of int or str | None
        The index or list of indices of the evoked dataset to read. FIF files
        can contain multiple datasets. If None, all datasets are returned as a
        list.
    baseline : None (default) or tuple of length 2
        The time interval to apply baseline correction. If None do not apply it.
        If baseline is (a, b) the interval is between "a (s)" and "b (s)". If a
        is None the beginning of the data is used and if b is None then b is set
        to the end of the interval. If baseline is equal ot (None, None) all the
        time interval is used.
    kind : str
        Either 'average' or 'standard_error', the type of data to read.
    proj : bool
        If False, available projectors won't be applied to the data.
    verbose : bool, str, int, or None
        If not None, override default verbose level (see mne.verbose).

    Returns
    -------
    evoked : Evoked (if condition is int or str) or list of Evoked (if
        condition is None or list)
        The evoked dataset(s).
    """
    check_fname(fname, 'evoked', ('-ave.fif', '-ave.fif.gz'))

    return_list = True
    if condition is None:
        evoked_node = _get_evoked_node(fname)
        condition = range(len(evoked_node))
    elif not isinstance(condition, list):
        condition = [condition]
        return_list = False

    out = [Evoked(fname, c, baseline=baseline, kind=kind, proj=proj,
           verbose=verbose) for c in condition]

    return out if return_list else out[0]


@deprecated("'write_evoked' will be removed in v0.9. Use 'write_evokeds.'")
def write_evoked(fname, evoked):
    """Write an evoked dataset to a file

    Parameters
    ----------
    fname : string
        The file name.
    evoked : instance of Evoked, or list of Evoked
        The evoked dataset to save, or a list of evoked datasets to save in one
        file. Note that the measurement info from the first evoked instance is
        used, so be sure that information matches.
    """

    if not isinstance(evoked, list):
        evoked = [evoked]

    # Create the file and save the essentials
    fid = start_file(fname)

    start_block(fid, FIFF.FIFFB_MEAS)
    write_id(fid, FIFF.FIFF_BLOCK_ID)
    if evoked[0].info['meas_id'] is not None:
        write_id(fid, FIFF.FIFF_PARENT_BLOCK_ID, evoked[0].info['meas_id'])

    # Write measurement info
    write_meas_info(fid, evoked[0].info)

    # One or more evoked data sets
    start_block(fid, FIFF.FIFFB_PROCESSED_DATA)
    for e in evoked:
        start_block(fid, FIFF.FIFFB_EVOKED)

        # Comment is optional
        if e.comment is not None and len(e.comment) > 0:
            write_string(fid, FIFF.FIFF_COMMENT, e.comment)

        # First and last sample
        write_int(fid, FIFF.FIFF_FIRST_SAMPLE, e.first)
        write_int(fid, FIFF.FIFF_LAST_SAMPLE, e.last)

        # The epoch itself
        start_block(fid, FIFF.FIFFB_ASPECT)

        write_int(fid, FIFF.FIFF_ASPECT_KIND, e._aspect_kind)
        write_int(fid, FIFF.FIFF_NAVE, e.nave)

        decal = np.zeros((e.info['nchan'], 1))
        for k in range(e.info['nchan']):
            decal[k] = 1.0 / (e.info['chs'][k]['cal']
                              * e.info['chs'][k].get('scale', 1.0))

        write_float_matrix(fid, FIFF.FIFF_EPOCH, decal * e.data)
        end_block(fid, FIFF.FIFFB_ASPECT)
        end_block(fid, FIFF.FIFFB_EVOKED)

    end_block(fid, FIFF.FIFFB_PROCESSED_DATA)
    end_block(fid, FIFF.FIFFB_MEAS)
    end_file(fid)


def write_evokeds(fname, evoked):
    """Write an evoked dataset to a file

    Parameters
    ----------
    fname : string
        The file name, which should end with -ave.fif or -ave.fif.gz.
    evoked : Evoked instance, or list of Evoked instances
        The evoked dataset, or list of evoked datasets, to save in one file.
        Note that the measurement info from the first evoked instance is used,
        so be sure that information matches.
    """
    check_fname(fname, 'evoked', ('-ave.fif', '-ave.fif.gz'))

    if not isinstance(evoked, list):
        evoked = [evoked]

    # Create the file and save the essentials
    with start_file(fname) as fid:

        start_block(fid, FIFF.FIFFB_MEAS)
        write_id(fid, FIFF.FIFF_BLOCK_ID)
        if evoked[0].info['meas_id'] is not None:
            write_id(fid, FIFF.FIFF_PARENT_BLOCK_ID, evoked[0].info['meas_id'])

        # Write measurement info
        write_meas_info(fid, evoked[0].info)

        # One or more evoked data sets
        start_block(fid, FIFF.FIFFB_PROCESSED_DATA)
        for e in evoked:
            start_block(fid, FIFF.FIFFB_EVOKED)

            # Comment is optional
            if e.comment is not None and len(e.comment) > 0:
                write_string(fid, FIFF.FIFF_COMMENT, e.comment)

            # First and last sample
            write_int(fid, FIFF.FIFF_FIRST_SAMPLE, e.first)
            write_int(fid, FIFF.FIFF_LAST_SAMPLE, e.last)

            # The epoch itself
            start_block(fid, FIFF.FIFFB_ASPECT)

            write_int(fid, FIFF.FIFF_ASPECT_KIND, e._aspect_kind)
            write_int(fid, FIFF.FIFF_NAVE, e.nave)

            decal = np.zeros((e.info['nchan'], 1))
            for k in range(e.info['nchan']):
                decal[k] = 1.0 / (e.info['chs'][k]['cal']
                                  * e.info['chs'][k].get('scale', 1.0))

            write_float_matrix(fid, FIFF.FIFF_EPOCH, decal * e.data)
            end_block(fid, FIFF.FIFFB_ASPECT)
            end_block(fid, FIFF.FIFFB_EVOKED)

        end_block(fid, FIFF.FIFFB_PROCESSED_DATA)
        end_block(fid, FIFF.FIFFB_MEAS)
        end_file(fid)


def _get_peak(data, times, tmin=None, tmax=None, mode='abs'):
    """Get feature-index and time of maximum signal from 2D array

    Note. This is a 'getter', not a 'finder'. For non-evoked type
    data and continuous signals, please use proper peak detection algorithms.

    Parameters
    ----------
    data : instance of numpy.ndarray (n_locations, n_times)
        The data, either evoked in sensor or source space.
    times : instance of numpy.ndarray (n_times)
        The times in seconds.
    tmin : float | None
        The minimum point in time to be considered for peak getting.
    tmax : float | None
        The maximum point in time to be considered for peak getting.
    mode : {'pos', 'neg', 'abs'}
        How to deal with the sign of the data. If 'pos' only positive
        values will be considered. If 'neg' only negative values will
        be considered. If 'abs' absolute values will be considered.
        Defaults to 'abs'.

    Returns
    -------
    max_loc : int
        The index of the feature with the maximum value.
    max_time : int
        The time point of the maximum response, index.
    """
    modes = ('abs', 'neg', 'pos')
    if mode not in modes:
        raise ValueError('The `mode` parameter must be `{modes}`. You gave '
                          'me `{mode}`'.format(modes='` or `'.join(modes),
                                               mode=mode))

    if tmin is None:
        tmin = times[0]
    if tmax is None:
        tmax = times[-1]

    if tmin < times.min():
        raise ValueError('The tmin value is out of bounds. It must be '
                         'within {0} and {1}'.format(times.min(), times.max()))
    if tmax > times.max():
        raise ValueError('The tmin value is out of bounds. It must be '
                         'within {0} and {1}'.format(times.min(), times.max()))
    if tmin >= tmax:
        raise ValueError('The tmin must be smaller than tmax')

    time_win = (times >= tmin) & (times <= tmax)
    mask = np.ones_like(data).astype(np.bool)
    mask[:, time_win] = False

    maxfun = np.argmax
    if mode == 'pos':
        if not np.any(data > 0):
            raise ValueError('No positive values encountered. Cannot '
                             'operate in pos mode.')
    elif mode == 'neg':
        if not np.any(data < 0):
            raise ValueError('No negative values encountered. Cannot '
                             'operate in neg mode.')
        maxfun = np.argmin

    masked_index = np.ma.array(np.abs(data) if mode == 'abs' else data,
                               mask=mask)

    max_loc, max_time = np.unravel_index(maxfun(masked_index), data.shape)

    return max_loc, max_time