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|
LOCUS MT291829 29774 bp RNA linear VRL 14-MAY-2020
DEFINITION Severe acute respiratory syndrome coronavirus 2 isolate
SARS-CoV-2/human/CHN/Wuhan_IME-WH04/2019, complete genome.
ACCESSION MT291829 GWHACAV01000001
VERSION MT291829.1
KEYWORDS .
SOURCE Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
ORGANISM Severe acute respiratory syndrome coronavirus 2
Viruses; Riboviria; Orthornavirae; Pisuviricota; Pisoniviricetes;
Nidovirales; Cornidovirineae; Coronaviridae; Orthocoronavirinae;
Betacoronavirus; Sarbecovirus.
REFERENCE 1 (bases 1 to 29774)
AUTHORS Fan,H., Qin,E., Wu,Y., Guo,Y., Zhang,X., Yong,Y., Hou,J., Xu,Z.,
Mu,J., Teng,Y., Mi,Z., Yang,R., Song,Y., Li,B. and Cui,Y.
TITLE Direct Submission
JOURNAL Submitted (06-APR-2020) Beijing Institute of Microbiology and
Epidemiology, Fengtai District, Beijing 100071, China
COMMENT This record was submitted to GenBank on behalf of the original
#submitter through Genome Warehouse (GWH,
https://bigd.big.ac.cn/gwh/) of the China National Center for
Bioinformation (CNCB)/National Genomics Data Center (NGDC,
https://bigd.big.ac.cn).
##Assembly-Data-START##
Assembly Method :: CLC Genomic Workbench v. V9.0
Assembly Name :: IME-WH04
Coverage :: 46
Sequencing Technology :: Ion Torrent X5Plus
##Assembly-Data-END##
FEATURES Location/Qualifiers
source 1..29774
/organism="Severe acute respiratory syndrome coronavirus
2"
/mol_type="genomic RNA"
/isolate="SARS-CoV-2/human/CHN/Wuhan_IME-WH04/2019"
/isolation_source="bronchoalveolar lavage fluid"
/host="Homo sapiens"
/db_xref="taxon:2697049"
/country="China: Wuhan"
/collection_date="2019-12-30"
/collected_by="Beijing Institute of Micribiology and
Epidemiology"
gene 178..21467
/gene="ORF1ab"
CDS join(178..13380,13380..21467)
/gene="ORF1ab"
/ribosomal_slippage
/codon_start=1
/product="ORF1ab polyprotein"
/protein_id="QIU81799.1"
/translation="MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQ
HLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGE
TLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN
WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQ
LDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFP
LNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTG
DFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESG
LKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNL
LEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN
FKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAA
ITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKL
KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLV
NKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEII
FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK
YCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEK
CSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF
KLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPE
EEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSG
YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD
DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA
PLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIA
EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN
LHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM
LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLIN
TLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS
KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVIT
FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH
NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK
WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG
DVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ
IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSK
ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYY
KKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVT
FFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWST
KPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGD
IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS
VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRI
KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTA
ALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET
IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWL
MWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE
CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRP
INPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPI
NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVN
TFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVEC
LKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALI
WNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWL
KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA
NKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLP
RVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA
YESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSG
RWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTN
DVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE
EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL
AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL
KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC
GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVN
VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV
LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW
LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFL
LPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR
TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR
GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYL
VSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL
LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL
CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK
SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN
NIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDA
DSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP
KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK
AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH
PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA
DAQSFLNRVCGVSAARLTPCGTGTSTDVVYRAFDIYNDKVAGFAKFLKTNCCRFQEKD
EDDNLIDSYFVVKRHTFSNYQHEETIYNLLKDCPAVAKHDFFKFRIDGDMVPHISRQR
LTKYTMADLVYALRHFDEGNCDTLKEILVTYNCCDDDYFNKKDWYDFVENPDILRVYA
NLGERVRQALLKTVQFCDAMRNAGIVGVLTLDNQDLNGNWYDFGDFIQTTPGSGVPVV
DSYYSLLMPILTLTRALTAESHVDTDLTKPYIKWDLLKYDFTEERLKLFDRYFKYWDQ
TYHPNCVNCLDDRCILHCANFNVLFSTVFPPTSFGPLVRKIFVDGVPFVVSTGYHFRE
LGVVHNQDVNLHSSRLSFKELLVYAADPAMHAASGNLLLDKRTTCFSVAALTNNVAFQ
TVKPGNFNKDFYDFAVSKGFFKEGSSVELKHFFFAQDGNAAISDYDYYRYNLPTMCDI
RQLLFVVEVVDKYFDCYDGGCINANQVIVNNLDKSAGFPFNKWGKARLYYDSMSYEDQ
DALFAYTKRNVIPTITQMNLKYAISAKNRARTVAGVSICSTMTNRQFHQKLLKSIAAT
RGATVVIGTSKFYGGWHNMLKTVYSDVENPHLMGWDYPKCDRAMPNMLRIMASLVLAR
KHTTCCSLSHRFYRLANECAQVLSEMVMCGGSLYVKPGGTSSGDATTAYANSVFNICQ
AVTANVNALLSTDGNKIADKYVRNLQHRLYECLYRNRDVDTDFVNEFYAYLRKHFSMM
ILSDDAVVCFNSTYASQGLVASIKNFKSVLYYQNNVFMSEAKCWTETDLTKGPHEFCS
QHTMLVKQGDDYVYLPYPDPSRILGAGCFVDDIVKTDGTLMIERFVSLAIDAYPLTKH
PNQEYADVFHLYLQYIRKLHDELTGHMLDMYSVMLTNDNTSRYWEPEFYEAMYTPHTV
LQAVGACVLCNSQTSLRCGACIRRPFLCCKCCYDHVISTSHKLVLSVNPYVCNAPGCD
VTDVTQLYLGGMSYYCKSHKPPISFPLCANGQVFGLYKNTCVGSDNVTDFNAIATCDW
TNAGDYILANTCTERLKLFAAETLKATEETFKLSYGIATVREVLSDRELHLSWEVGKP
RPPLNRNYVFTGYRVTKNSKVQIGEYTFEKGDYGDAVVYRGTTTYKLNVGDYFVLTSH
TVMPLSAPTLVPQEHYVRITGLYPTLNISDEFSSNVANYQKVGMQKYSTLQGPPGTGK
SHFAIGLALYYPSARIVYTACSHAAVDALCEKALKYLPIDKCSRIIPARARVECFDKF
KVNSTLEQYVFCTVNALPETTADIVVFDEISMATNYDLSVVNARLRAKHYVYIGDPAQ
LPAPRTLLTKGTLEPEYFNSVCRLMKTIGPDMFLGTCRRCPAEIVDTVSALVYDNKLK
AHKDKSAQCFKMFYKGVITHDVSSAINRPQIGVVREFLTRNPAWRKAVFISPYNSQNA
VASKILGLPTQTVDSSQGSEYDYVIFTQTTETAHSCNVNRFNVAITRAKVGILCIMSD
RDLYDKLQFTSLEIPRRNVATLQAENVTGLFKDCSKVITGLHPTQAPTHLSVDTKFKT
EGLCVDIPGIPKDMTYRRLISMMGFKMNYQVNGYPNMFITREEAIRHVRAWIGFDVEG
CHATREAVGTNLPLQLGFSTGVNLVAVPTGYVDTPNNTDFSRVSAKPPPGDQFKHLIP
LMYKGLPWNVVRIKIVQMLSDTLKNLSDRVVFVLWAHGFELTSMKYFVKIGPERTCCL
CDRRATCFSTASDTYACWHHSIGFDYVYNPFMIDVQQWGFTGNLQSNHDLYCQVHGNA
HVASCDAIMTRCLAVHECFVKRVDWTIEYPIIGDELKINAACRKVQHMVVKAALLADK
FPVLHDIGNPKAIKCVPQADVEWKFYDAQPCSDKAYKIEELFYSYATHSDKFTDGVCL
FWNCNVDRYPANSIVCRFDTRVLSNLNLPGCDGGSLYVNKHAFHTPAFDKSAFVNLKQ
LPFFYYSDSPCESHGKQVVSDIDYVPLKSATCITRCNLGGAVCRHHANEYRLYLDAYN
MMISAGFSLWVYKQFDTYNLWNTFTRLQSLENVAFNVVNKGHFDGQQGEVPVSIINNT
VYTKVDGVDVELFENKTTLPVNVAFELWAKRNIKPVPEVKILNNLGVDIAANTVIWDY
KRDAPAHISTIGVCSMTDIAKKPTETICAPLTVFFDGRVDGQVDLFRNARNGVLITEG
SVKGLQPSVGPKQASLNGVTLIGEAVKTQFNYYKKVDGVVQQLPETYFTQSRNLQEFK
PRSQMEIDFLELAMDEFIERYKLEGYAFEHIVYGDFSHSQLGGLHLLIGLAKRFKESP
FELEDFIPMDSTVKNYFITDAQTGSSKCVCSVIDLLLDDFVEIIKSQDLSVVSKVVKV
TIDYTEISFMLWCKDGHVETFYPKLQSSQAWQPGVAMPNLYKMQRMLLEKCDLQNYGD
SATLPKGIMMNVAKYTQLCQYLNTLTLAVPYNMRVIHFGAGSDKGVAPGTAVLRQWLP
TGTLLVDSDLNDFVSDADSTLIGDCATVHTANKWDLIISDMYDPKTKNVTKENDSKEG
FFTYICGFIQQKLALGGSVAIKITEHSWNADLYKLMGHFAWWTAFVTNVNASSSEAFL
IGCNYLGKPREQIDGYVMHANYIFWRNTNPIQLSSYSLFDMSKFPLKLRGTAVMSLKE
GQINDMILSLLSKGRLIIRENNRVVISSDVLVNN"
mat_peptide 178..717
/gene="ORF1ab"
/product="leader protein"
mat_peptide 718..2631
/gene="ORF1ab"
/product="nsp2"
mat_peptide 2632..8466
/gene="ORF1ab"
/product="nsp3"
mat_peptide 8467..9966
/gene="ORF1ab"
/product="nsp4"
mat_peptide 9967..10884
/gene="ORF1ab"
/product="3C-like proteinase"
mat_peptide 10885..11754
/gene="ORF1ab"
/product="nsp6"
mat_peptide 11755..12003
/gene="ORF1ab"
/product="nsp7"
mat_peptide 12004..12597
/gene="ORF1ab"
/product="nsp8"
mat_peptide 12598..12936
/gene="ORF1ab"
/product="nsp9"
mat_peptide 12937..13353
/gene="ORF1ab"
/product="nsp10"
mat_peptide join(13354..13380,13380..13382,13378..13380,13380..16148)
/gene="ORF1ab"
/product="RNA-dependent RNA polymerase"
mat_peptide 16149..17951
/gene="ORF1ab"
/product="helicase"
mat_peptide 17952..19532
/gene="ORF1ab"
/product="3'-to-5' exonuclease"
mat_peptide 19533..20570
/gene="ORF1ab"
/product="endoRNAse"
mat_peptide 20571..21464
/gene="ORF1ab"
/product="2'-O-ribose methyltransferase"
CDS 178..13395
/gene="ORF1ab"
/codon_start=1
/product="ORF1a polyprotein"
/protein_id="QIU81800.1"
/translation="MESLVPGFNEKTHVQLSLPVLQVRDVLVRGFGDSVEEVLSEARQ
HLKDGTCGLVEVEKGVLPQLEQPYVFIKRSDARTAPHGHVMVELVAELEGIQYGRSGE
TLGVLVPHVGEIPVAYRKVLLRKNGNKGAGGHSYGADLKSFDLGDELGTDPYEDFQEN
WNTKHSSGVTRELMRELNGGAYTRYVDNNFCGPDGYPLECIKDLLARAGKASCTLSEQ
LDFIDTKRGVYCCREHEHEIAWYTERSEKSYELQTPFEIKLAKKFDTFNGECPNFVFP
LNSIIKTIQPRVEKKKLDGFMGRIRSVYPVASPNECNQMCLSTLMKCDHCGETSWQTG
DFVKATCEFCGTENLTKEGATTCGYLPQNAVVKIYCPACHNSEVGPEHSLAEYHNESG
LKTILRKGGRTIAFGGCVFSYVGCHNKCAYWVPRASANIGCNHTGVVGEGSEGLNDNL
LEILQKEKVNINIVGDFKLNEEIAIILASFSASTSAFVETVKGLDYKAFKQIVESCGN
FKVTKGKAKKGAWNIGEQKSILSPLYAFASEAARVVRSIFSRTLETAQNSVRVLQKAA
ITILDGISQYSLRLIDAMMFTSDLATNNLVVMAYITGGVVQLTSQWLTNIFGTVYEKL
KPVLDWLEEKFKEGVEFLRDGWEIVKFISTCACEIVGGQIVTCAKEIKESVQTFFKLV
NKFLALCADSIIIGGAKLKALNLGETFVTHSKGLYRKCVKSREETGLLMPLKAPKEII
FLEGETLPTEVLTEEVVLKTGDLQPLEQPTSEAVEAPLVGTPVCINGLMLLEIKDTEK
YCALAPNMMVTNNTFTLKGGAPTKVTFGDDTVIEVQGYKSVNITFELDERIDKVLNEK
CSAYTVELGTEVNEFACVVADAVIKTLQPVSELLTPLGIDLDEWSMATYYLFDESGEF
KLASHMYCSFYPPDEDEEEGDCEEEEFEPSTQYEYGTEDDYQGKPLEFGATSAALQPE
EEQEEDWLDDDSQQTVGQQDGSEDNQTTTIQTIVEVQPQLEMELTPVVQTIEVNSFSG
YLKLTDNVYIKNADIVEEAKKVKPTVVVNAANVYLKHGGGVAGALNKATNNAMQVESD
DYIATNGPLKVGGSCVLSGHNLAKHCLHVVGPNVNKGEDIQLLKSAYENFNQHEVLLA
PLLSAGIFGADPIHSLRVCVDTVRTNVYLAVFDKNLYDKLVSSFLEMKSEKQVEQKIA
EIPKEEVKPFITESKPSVEQRKQDDKKIKACVEEVTTTLEETKFLTENLLLYIDINGN
LHPDSATLVSDIDITFLKKDAPYIVGDVVQEGVLTAVVIPTKKAGGTTEMLAKALRKV
PTDNYITTYPGQGLNGYTVEEAKTVLKKCKSAFYILPSIISNEKQEILGTVSWNLREM
LAHAEETRKLMPVCVETKAIVSTIQRKYKGIKIQEGVVDYGARFYFYTSKTTVASLIN
TLNDLNETLVTMPLGYVTHGLNLEEAARYMRSLKVPATVSVSSPDAVTAYNGYLTSSS
KTPEEHFIETISLAGSYKDWSYSGQSTQLGIEFLKRGDKSVYYTSNPTTFHLDGEVIT
FDNLKTLLSLREVRTIKVFTTVDNINLHTQVVDMSMTYGQQFGPTYLDGADVTKIKPH
NSHEGKTFYVLPNDDTLRVEAFEYYHTTDPSFLGRYMSALNHTKKWKYPQVNGLTSIK
WADNNCYLATALLTLQQIELKFNPPALQDAYYRARAGEAANFCALILAYCNKTVGELG
DVRETMSYLFQHANLDSCKRVLNVVCKTCGQQQTTLKGVEAVMYMGTLSYEQFKKGVQ
IPCTCGKQATKYLVQQESPFVMMSAPPAQYELKHGTFTCASEYTGNYQCGHYKHITSK
ETLYCIDGALLTKSSEYKGPITDVFYKENSYTTTIKPVTYKLDGVVCTEIDPKLDNYY
KKDNSYFTEQPIDLVPNQPYPNASFDNFKFVCDNIKFADDLNQLTGYKKPASRELKVT
FFPDLNGDVVAIDYKHYTPSFKKGAKLLHKPIVWHVNNATNKATYKPNTWCIRCLWST
KPVETSNSFDVLKSEDAQGMDNLACEDLKPVSEEVVENPTIQKDVLECNVKTTEVVGD
IILKPANNSLKITEEVGHTDLMAAYVDNSSLTIKKPNELSRVLGLKTLATHGLAAVNS
VPWDTIANYAKPFLNKVVSTTTNIVTRCLNRVCTNYMPYFFTLLLQLCTFTRSTNSRI
KASMPTTIAKNTVKSVGKFCLEASFNYLKSPNFSKLINIIIWFLLLSVCLGSLIYSTA
ALGVLMSNLGMPSYCTGYREGYLNSTNVTIATYCTGSIPCSVCLSGLDSLDTYPSLET
IQITISSFKWDLTAFGLVAEWFLAYILFTRFFYVLGLAAIMQLFFSYFAVHFISNSWL
MWLIINLVQMAPISAMVRMYIFFASFYYVWKSYVHVVDGCNSSTCMMCYKRNRATRVE
CTTIVNGVRRSFYVYANGGKGFCKLHNWNCVNCDTFCAGSTFISDEVARDLSLQFKRP
INPTDQSSYIVDSVTVKNGSIHLYFDKAGQKTYERHSLSHFVNLDNLRANNTKGSLPI
NVIVFDGKSKCEESSAKSASVYYSQLMCQPILLLDQALVSDVGDSAEVAVKMFDAYVN
TFSSTFNVPMEKLKTLVATAEAELAKNVSLDNVLSTFISAARQGFVDSDVETKDVVEC
LKLSHQSDIEVTGDSCNNYMLTYNKVENMTPRDLGACIDCSARHINAQVAKSHNIALI
WNVKDFMSLSEQLRKQIRSAAKKNNLPFKLTCATTRQVVNVVTTKIALKGGKIVNNWL
KQLIKVTLVFLFVAAIFYLITPVHVMSKHTDFSSEIIGYKAIDGGVTRDIASTDTCFA
NKHADFDTWFSQRGGSYTNDKACPLIAAVITREVGFVVPGLPGTILRTTNGDFLHFLP
RVFSAVGNICYTPSKLIEYTDFATSACVLAAECTIFKDASGKPVPYCYDTNVLEGSVA
YESLRPDTRYVLMDGSIIQFPNTYLEGSVRVVTTFDSEYCRHGTCERSEAGVCVSTSG
RWVLNNDYYRSLPGVFCGVDAVNLLTNMFTPLIQPIGALDISASIVAGGIVAIVVTCL
AYYFMRFRRAFGEYSHVVAFNTLLFLMSFTVLCLTPVYSFLPGVYSVIYLYLTFYLTN
DVSFLAHIQWMVMFTPLVPFWITIAYIICISTKHFYWFFSNYLKRRVVFNGVSFSTFE
EAALCTFLLNKEMYLKLRSDVLLPLTQYNRYLALYNKYKYFSGAMDTTSYREAACCHL
AKALNDFSNSGSDVLYQPPQTSITSAVLQSGFRKMAFPSGKVEGCMVQVTCGTTTLNG
LWLDDVVYCPRHVICTSEDMLNPNYEDLLIRKSNHNFLVQAGNVQLRVIGHSMQNCVL
KLKVDTANPKTPKYKFVRIQPGQTFSVLACYNGSPSGVYQCAMRPNFTIKGSFLNGSC
GSVGFNIDYDCVSFCYMHHMELPTGVHAGTDLEGNFYGPFVDRQTAQAAGTDTTITVN
VLAWLYAAVINGDRWFLNRFTTTLNDFNLVAMKYNYEPLTQDHVDILGPLSAQTGIAV
LDMCASLKELLQNGMNGRTILGSALLEDEFTPFDVVRQCSGVTFQSAVKRTIKGTHHW
LLLTILTSLLVLVQSTQWSLFFFLYENAFLPFAMGIIAMSAFAMMFVKHKHAFLCLFL
LPSLATVAYFNMVYMPASWVMRIMTWLDMVDTSLSGFKLKDCVMYASAVVLLILMTAR
TVYDDGARRVWTLMNVLTLVYKVYYGNALDQAISMWALIISVTSNYSGVVTTVMFLAR
GIVFMCVEYCPIFFITGNTLQCIMLVYCFLGYFCTCYFGLFCLLNRYFRLTLGVYDYL
VSTQEFRYMNSQGLLPPKNSIDAFKLNIKLLGVGGKPCIKVATVQSKMSDVKCTSVVL
LSVLQQLRVESSSKLWAQCVQLHNDILLAKDTTEAFEKMVSLLSVLLSMQGAVDINKL
CEEMLDNRATLQAIASEFSSLPSYAAFATAQEAYEQAVANGDSEVVLKKLKKSLNVAK
SEFDRDAAMQRKLEKMADQAMTQMYKQARSEDKRAKVTSAMQTMLFTMLRKLDNDALN
NIINNARDGCVPLNIIPLTTAAKLMVVIPDYNTYKNTCDGTTFTYASALWEIQQVVDA
DSKIVQLSEISMDNSPNLAWPLIVTALRANSAVKLQNNELSPVALRQMSCAAGTTQTA
CTDDNALAYYNTTKGGRFVLALLSDLQDLKWARFPKSDGTGTIYTELEPPCRFVTDTP
KGPKVKYLYFIKGLNNLNRGMVLGSLAATVRLQAGNATEVPANSTVLSFCAFAVDAAK
AYKDYLASGGQPITNCVKMLCTHTGTGQAITVTPEANMDQESFGGASCCLYCRCHIDH
PNPKGFCDLKGKYVQIPTTCANDPVGFTLKNTVCTVCGMWKGYGCSCDQLREPMLQSA
DAQSFLNGFAV"
mat_peptide 178..717
/gene="ORF1ab"
/product="leader protein"
mat_peptide 718..2631
/gene="ORF1ab"
/product="nsp2"
mat_peptide 2632..8466
/gene="ORF1ab"
/product="nsp3"
mat_peptide 8467..9966
/gene="ORF1ab"
/product="nsp4"
mat_peptide 9967..10884
/gene="ORF1ab"
/product="3C-like proteinase"
mat_peptide 10885..11754
/gene="ORF1ab"
/product="nsp6"
mat_peptide 11755..12003
/gene="ORF1ab"
/product="nsp7"
mat_peptide 12004..12597
/gene="ORF1ab"
/product="nsp8"
mat_peptide 12598..12936
/gene="ORF1ab"
/product="nsp9"
mat_peptide 12937..13353
/gene="ORF1ab"
/product="nsp10"
mat_peptide 13354..13392
/gene="ORF1ab"
/product="nsp11"
stem_loop 13388..13415
/gene="ORF1ab"
/note="Coronavirus frameshifting stimulation element
stem-loop 1"
stem_loop 13400..13454
/gene="ORF1ab"
/note="Coronavirus frameshifting stimulation element
stem-loop 2"
gene 21475..25296
/gene="S"
CDS 21475..25296
/gene="S"
/codon_start=1
/product="surface glycoprotein"
/protein_id="QIU81801.1"
/translation="MFVFLVLLPLVSSQCVNLTTRTQLPPAYTNSFTRGVYYPDKVFR
SSVLHSTQDLFLPFFSNVTWFHAIHVSGTNGTKRFDNPVLPFNDGVYFASTEKSNIIR
GWIFGTTLDSKTQSLLIVNNATNVVIKVCEFQFCNDPFLGVYYHKNNKSWMESEFRVY
SSANNCTFEYVSQPFLMDLEGKQGNFKNLREFVFKNIDGYFKIYSKHTPINLVRDLPQ
GFSALEPLVDLPIGINITRFQTLLALHRSYLTPGDSSSGWTAGAAAYYVGYLQPRTFL
LKYNENGTITDAVDCALDPLSETKCTLKSFTVEKGIYQTSNFRVQPTESIVRFPNITN
LCPFGEVFNATRFASVYAWNRKRISNCVADYSVLYNSASFSTFKCYGVSPTKLNDLCF
TNVYADSFVIRGDEVRQIAPGQTGKIADYNYKLPDDFTGCVIAWNSNNLDSKVGGNYN
YLYRLFRKSNLKPFERDISTEIYQAGSTPCNGVEGFNCYFPLQSYGFQPTNGVGYQPY
RVVVLSFELLHAPATVCGPKKSTNLVKNKCVNFNFNGLTGTGVLTESNKKFLPFQQFG
RDIADTTDAVRDPQTLEILDITPCSFGGVSVITPGTNTSNQVAVLYQDVNCTEVPVAI
HADQLTPTWRVYSTGSNVFQTRAGCLIGAEHVNNSYECDIPIGAGICASYQTQTNSPR
RARSVASQSIIAYTMSLGAENSVAYSNNSIAIPTNFTISVTTEILPVSMTKTSVDCTM
YICGDSTECSNLLLQYGSFCTQLNRALTGIAVEQDKNTQEVFAQVKQIYKTPPIKDFG
GFNFSQILPDPSKPSKRSFIEDLLFNKVTLADAGFIKQYGDCLGDIAARDLICAQKFN
GLTVLPPLLTDEMIAQYTSALLAGTITSGWTFGAGAALQIPFAMQMAYRFNGIGVTQN
VLYENQKLIANQFNSAIGKIQDSLSSTASALGKLQDVVNQNAQALNTLVKQLSSNFGA
ISSVLNDILSRLDKVEAEVQIDRLITGRLQSLQTYVTQQLIRAAEIRASANLAATKMS
ECVLGQSKRVDFCGKGYHLMSFPQSAPHGVVFLHVTYVPAQEKNFTTAPAICHDGKAH
FPREGVFVSNGTHWFVTQRNFYEPQIITTDNTFVSGNCDVVIGIVNNTVYDPLQPELD
SFKEELDKYFKNHTSPDVDLGDISGINASVVNIQKEIDRLNEVAKNLNESLIDLQELG
KYEQYIKWPWYIWLGFIAGLIAIVMVTIMLCCMTSCCSCLKGCCSCGSCCKFDEDDSE
PVLKGVKLHYT"
gene 25305..26132
/gene="ORF3a"
CDS 25305..26132
/gene="ORF3a"
/codon_start=1
/product="ORF3a protein"
/protein_id="QIU81802.1"
/translation="MDLFMRIFTIGTVTLKQGEIKDATPSDFVRATATIPIQASLPFG
WLIVGVALLAVFQSASKIITLKKRWQLALSKGVHFVCNLLLLFVTVYSHLLLVAAGLE
APFLYLYALVYFLQSINFVRIIMRLWLCWKCRSKNPLLYDANYFLCWHTNCYDYCIPY
NSVTSSIVITSGDGTTSPISEHDYQIGGYTEKWESGVKDCVVLHSYFTSDYYQLYSTQ
LSTDTGVEHVTFFIYNKIVDEPEEHVQIHTIDGSSGVVNPVMEPIYDEPTTTTSVPL"
gene 26157..26384
/gene="E"
CDS 26157..26384
/gene="E"
/codon_start=1
/product="envelope protein"
/protein_id="QIU81803.1"
/translation="MYSFVSEETGTLIVNSVLLFLAFVVFLLVTLAILTALRLCAYCC
NIVNVSLVKPSFYVYSRVKNLNSSRVPDLLV"
gene 26435..27103
/gene="M"
CDS 26435..27103
/gene="M"
/codon_start=1
/product="membrane glycoprotein"
/protein_id="QIU81804.1"
/translation="MADSNGTITVEELKKLLEQWNLVIGFLFLTWICLLQFAYANRNR
FLYIIKLIFLWLLWPVTLACFVLAAVYRINWITGGIAIAMACLVGLMWLSYFIASFRL
FARTRSMWSFNPETNILLNVPLHGTILTRPLLESELVIGAVILRGHLRIAGHHLGRCD
IKDLPKEITVATSRTLSYYKLGASQRVAGDSGFAAYSRYRIGNYKLNTDHSSSSDNIA
LLVQ"
gene 27114..27299
/gene="ORF6"
CDS 27114..27299
/gene="ORF6"
/codon_start=1
/product="ORF6 protein"
/protein_id="QIU81805.1"
/translation="MFHLVDFQVTIAEILLIIMRTFKVSIWNLDYIINLIIKNLSKSL
TENKYSQLDEEQPMEID"
gene 27306..27671
/gene="ORF7a"
CDS 27306..27671
/gene="ORF7a"
/codon_start=1
/product="ORF7a protein"
/protein_id="QIU81806.1"
/translation="MKIILFLALITLATCELYHYQECVRGTTVLLKEPCSSGTYEGNS
PFHPLADNKFALTCFSTQFAFACPDGVKHVYQLRARSVSPKLFIRQEEVQELYSPIFL
IVAAIVFITLCFTLKRKTE"
gene 27668..27799
/gene="ORF7b"
CDS 27668..27799
/gene="ORF7b"
/codon_start=1
/product="ORF7b"
/protein_id="QIU81807.1"
/translation="MIELSLIDFYLCFLAFLLFLVLIMLIIFWFSLELQDHNETCHA"
gene 27806..28171
/gene="ORF8"
CDS 27806..28171
/gene="ORF8"
/codon_start=1
/product="ORF8 protein"
/protein_id="QIU81808.1"
/translation="MKFLVFLGIITTVAAFHQECSLQSCTQHQPYVVDDPCPIHFYSK
WYIRVGARKSAPLIELCVDEAGSKSPIQYIDIGNYTVSCLPFTINCQEPKLGSLVVRC
SFYEDFLEYHDVRVVLDFI"
gene 28186..29445
/gene="N"
CDS 28186..29445
/gene="N"
/codon_start=1
/product="nucleocapsid phosphoprotein"
/protein_id="QIU81809.1"
/translation="MSDNGPQNQRNAPRITFGGPSDSTGSNQNGERSGARSKQRRPQG
LPNNTASWFTALTQHGKEDLKFPRGQGVPINTNSSPDDQIGYYRRATRRIRGGDGKMK
DLSPRWYFYYLGTGPEAGLPYGANKDGIIWVATEGALNTPKDHIGTRNPANNAAIVLQ
LPQGTTLPKGFYAEGSRGGSQASSRSSSRSRNSSRNSTPGSSRGTSPARMAGNGGDAA
LALLLLDRLNQLESKMSGKGQQQQGQTVTKKSAAEASKKPRQKRTATKAYNVTQAFGR
RGPEQTQGNFGDQELIRQGTDYKHWPQIAQFAPSASAFFGMSRIGMEVTPSGTWLTYT
GAIKLDDKDPNFKDQVILLNKHIDAYKTFPPTEPKKDKKKKADETQALPQRQKKQQTV
TLLPAADLDDFSKQLQQSMSSADSTQA"
gene 29470..29586
/gene="ORF10"
CDS 29470..29586
/gene="ORF10"
/codon_start=1
/product="ORF10 protein"
/protein_id="QIU81810.1"
/translation="MGYINVFAFPFTIYSLLLCRMNSRNYIAQVDVVNFNLT"
stem_loop 29521..29556
/gene="ORF10"
/note="Coronavirus 3' UTR pseudoknot stem-loop 1"
stem_loop 29541..29569
/gene="ORF10"
/note="Coronavirus 3' UTR pseudoknot stem-loop 2"
stem_loop 29640..29680
/note="Coronavirus 3' stem-loop II-like motif (s2m)"
ORIGIN
1 tggctgtcac tcggctgcat gcttagtgca ctcacgcagt ataattaata actaattact
61 gtcgttgaca ggacacgagt aactcgtcta tcttctgcag gctgcttacg gtttcgtccg
121 tgttgcagcc gatcatcagc acatctaggt ttcgtccggg tgtgaccgaa aggtaagatg
181 gagagccttg tccctggttt caacgagaaa acacacgtcc aactcagttt gcctgtttta
241 caggttcgcg acgtgctcgt acgtggcttt ggagactccg tggaggaggt cttatcagag
301 gcacgtcaac atcttaaaga tggcacttgt ggcttagtag aagttgaaaa aggcgttttg
361 cctcaacttg aacagcccta tgtgttcatc aaacgttcgg atgctcgaac tgcacctcat
421 ggtcatgtta tggttgagct ggtagcagaa ctcgaaggca ttcagtacgg tcgtagtggt
481 gagacacttg gtgtccttgt ccctcatgtg ggcgaaatac cagtggctta ccgcaaggtt
541 cttcttcgta agaacggtaa taaaggagct ggtggccata gttacggcgc cgatctaaag
601 tcatttgact taggcgacga gcttggcact gatccttatg aagattttca agaaaactgg
661 aacactaaac atagcagtgg tgttacccgt gaactcatgc gtgagcttaa cggaggggca
721 tacactcgct atgtcgataa caacttctgt ggccctgatg gctaccctct tgagtgcatt
781 aaagaccttc tagcacgtgc tggtaaagct tcatgcactt tgtccgaaca actggacttt
841 attgacacta agaggggtgt atactgctgc cgtgaacatg agcatgaaat tgcttggtac
901 acggaacgtt ctgaaaagag ctatgaattg cagacacctt ttgaaattaa attggcaaag
961 aaatttgaca ccttcaatgg ggaatgtcca aattttgtat ttcccttaaa ttccataatc
1021 aagactattc aaccaagggt tgaaaagaaa aagcttgatg gctttatggg tagaattcga
1081 tctgtctatc cagttgcgtc accaaatgaa tgcaaccaaa tgtgcctttc aactctcatg
1141 aagtgtgatc attgtggtga aacttcatgg cagacgggcg attttgttaa agccacttgc
1201 gaattttgtg gcactgagaa tttgactaaa gaaggtgcca ctacttgtgg ttacttaccc
1261 caaaatgctg ttgttaaaat ttattgtcca gcatgtcaca attcagaagt aggacctgag
1321 catagtcttg ccgaatacca taatgaatct ggcttgaaaa ccattcttcg taagggtggt
1381 cgcactattg cctttggagg ctgtgtgttc tcttatgttg gttgccataa caagtgtgcc
1441 tattgggttc cacgtgctag cgctaacata ggttgtaacc atacaggtgt tgttggagaa
1501 ggttccgaag gtcttaatga caaccttctt gaaatactcc aaaaagagaa agtcaacatc
1561 aatattgttg gtgactttaa acttaatgaa gagatcgcca ttattttggc atctttttct
1621 gcttccacaa gtgcttttgt ggaaactgtg aaaggtttgg attataaagc attcaaacaa
1681 attgttgaat cctgtggtaa ttttaaagtt acaaaaggaa aagctaaaaa aggtgcctgg
1741 aatattggtg aacagaaatc aatactgagt cctctttatg catttgcatc agaggctgct
1801 cgtgttgtac gatcaatttt ctcccgcact cttgaaactg ctcaaaattc tgtgcgtgtt
1861 ttacagaagg ccgctataac aatactagat ggaatttcac agtattcact gagactcatt
1921 gatgctatga tgttcacatc tgatttggct actaacaatc tagttgtaat ggcctacatt
1981 acaggtggtg ttgttcagtt gacttcgcag tggctaacta acatctttgg cactgtttat
2041 gaaaaactca aacccgtcct tgattggctt gaagagaagt ttaaggaagg tgtagagttt
2101 cttagagacg gttgggaaat tgttaaattt atctcaacct gtgcttgtga aattgtcggt
2161 ggacaaattg tcacctgtgc aaaggaaatt aaggagagtg ttcagacatt ctttaagctt
2221 gtaaataaat ttttggcttt gtgtgctgac tctatcatta ttggtggagc taaacttaaa
2281 gccttgaatt taggtgaaac atttgtcacg cactcaaagg gattgtacag aaagtgtgtt
2341 aaatccagag aagaaactgg cctactcatg cctctaaaag ccccaaaaga aattatcttc
2401 ttagagggag aaacacttcc cacagaagtg ttaacagagg aagttgtctt gaaaactggt
2461 gatttacaac cattagaaca acctactagt gaagctgttg aagctccatt ggttggtaca
2521 ccagtttgta ttaacgggct tatgttgctc gaaatcaaag acacagaaaa gtactgtgcc
2581 cttgcaccta atatgatggt aacaaacaat accttcacac tcaaaggcgg tgcaccaaca
2641 aaggttactt ttggtgatga cactgtgata gaagtgcaag gttacaagag tgtgaatatc
2701 acttttgaac ttgatgaaag gattgataaa gtacttaatg agaagtgctc tgcctataca
2761 gttgaactcg gtacagaagt aaatgagttc gcctgtgttg tggcagatgc tgtcataaaa
2821 actttgcaac cagtatctga attacttaca ccactgggca ttgatttaga tgagtggagt
2881 atggctacat actacttatt tgatgagtct ggtgagttta aattggcttc acatatgtat
2941 tgttctttct accctccaga tgaggatgaa gaagaaggtg attgtgaaga agaagagttt
3001 gagccatcaa ctcaatatga gtatggtact gaagatgatt accaaggtaa acctttggaa
3061 tttggtgcca cttctgctgc tcttcaacct gaagaagagc aagaagaaga ttggttagat
3121 gatgatagtc aacaaactgt tggtcaacaa gacggcagtg aggacaatca gacaactact
3181 attcaaacaa ttgttgaggt tcaacctcaa ttagagatgg aacttacacc agttgttcag
3241 actattgaag tgaatagttt tagtggttat ttaaaactta ctgacaatgt atacattaaa
3301 aatgcagaca ttgtggaaga agctaaaaag gtaaaaccaa cagtggttgt taatgcagcc
3361 aatgtttacc ttaaacatgg aggaggtgtt gcaggagcct taaataaggc tactaacaat
3421 gccatgcaag ttgaatctga tgattacata gctactaatg gaccacttaa agtgggtggt
3481 agttgtgttt taagcggaca caatcttgct aaacactgtc ttcatgttgt cggcccaaat
3541 gttaacaaag gtgaagacat tcaacttctt aagagtgctt atgaaaattt taatcagcac
3601 gaagttctac ttgcaccatt attatcagct ggtatttttg gtgctgaccc tatacattct
3661 ttaagagttt gtgtagatac tgttcgcaca aatgtctact tagctgtctt tgataaaaat
3721 ctctatgaca aacttgtttc aagctttttg gaaatgaaga gtgaaaagca agttgaacaa
3781 aagatcgctg agattcctaa agaggaagtt aagccattta taactgaaag taaaccttca
3841 gttgaacaga gaaaacaaga tgataagaaa atcaaagctt gtgttgaaga agttacaaca
3901 actctggaag aaactaagtt cctcacagaa aacttgttac tttatattga cattaatggc
3961 aatcttcatc cagattctgc cactcttgtt agtgacattg acatcacttt cttaaagaaa
4021 gatgctccat atatagtggg tgatgttgtt caagagggtg ttttaactgc tgtggttata
4081 cctactaaaa aggctggtgg cactactgaa atgctagcga aagctttgag aaaagtgcca
4141 acagacaatt atataaccac ttacccgggt cagggtttaa atggttacac tgtagaggag
4201 gcaaagacag tgcttaaaaa gtgtaaaagt gccttttaca ttctaccatc tattatctct
4261 aatgagaagc aagaaattct tggaactgtt tcttggaatt tgcgagaaat gcttgcacat
4321 gcagaagaaa cacgcaaatt aatgcctgtc tgtgtggaaa ctaaagccat agtttcaact
4381 atacagcgta aatataaggg tattaaaata caagagggtg tggttgatta tggtgctaga
4441 ttttactttt acaccagtaa aacaactgta gcgtcactta tcaacacact taacgatcta
4501 aatgaaactc ttgttacaat gccacttggc tatgtaacac atggcttaaa tttggaagaa
4561 gctgctcggt atatgagatc tctcaaagtg ccagctacag tttctgtttc ttcacctgat
4621 gctgttacag cgtataatgg ttatcttact tcttcttcta aaacacctga agaacatttt
4681 attgaaacca tctcacttgc tggttcctat aaagattggt cctattctgg acaatctaca
4741 caactaggta tagaatttct taagagaggt gataaaagtg tatattacac tagtaatcct
4801 accacattcc acctagatgg tgaagttatc acctttgaca atcttaagac acttctttct
4861 ttgagagaag tgaggactat taaggtgttt acaacagtag acaacattaa cctccacacg
4921 caagttgtgg acatgtcaat gacatatgga caacagtttg gtccaactta tttggatgga
4981 gctgatgtta ctaaaataaa acctcataat tcacatgaag gtaaaacatt ttatgtttta
5041 cctaatgatg acactctacg tgttgaggct tttgagtact accacacaac tgatcctagt
5101 tttctgggta ggtacatgtc agcattaaat cacactaaaa agtggaaata cccacaagtt
5161 aatggtttaa cttctattaa atgggcagat aacaactgtt atcttgccac tgcattgtta
5221 acactccaac aaatagagtt gaagtttaat ccacctgctc tacaagatgc ttattacaga
5281 gcaagggctg gtgaagctgc taacttttgt gcacttatct tagcctactg taataagaca
5341 gtaggtgagt taggtgatgt tagagaaaca atgagttact tgtttcaaca tgccaattta
5401 gattcttgca aaagagtctt gaacgtggtg tgtaaaactt gtggacaaca gcagacaacc
5461 cttaagggtg tagaagctgt tatgtacatg ggcacacttt cttatgaaca atttaagaaa
5521 ggtgttcaga taccttgtac gtgtggtaaa caagctacaa aatatctagt acaacaggag
5581 tcaccttttg ttatgatgtc agcaccacct gctcagtatg aacttaagca tggtacattt
5641 acttgtgcta gtgagtacac tggtaattac cagtgtggtc actataaaca tataacttct
5701 aaagaaactt tgtattgcat agacggtgct ttacttacaa agtcctcaga atacaaaggt
5761 cctattacgg atgttttcta caaagaaaac agttacacaa caaccataaa accagttact
5821 tataaattgg atggtgttgt ttgtacagaa attgacccta agttggacaa ttattataag
5881 aaagacaatt cttatttcac agagcaacca attgatcttg taccaaacca accatatcca
5941 aacgcaagct tcgataattt taagtttgta tgtgataata tcaaatttgc tgatgattta
6001 aaccagttaa ctggttataa gaaacctgct tcaagagagc ttaaagttac atttttccct
6061 gacttaaatg gtgatgtggt ggctattgat tataaacact acacaccctc ttttaagaaa
6121 ggagctaaat tgttacataa acctattgtt tggcatgtta acaatgcaac taataaagcc
6181 acgtataaac caaatacctg gtgtatacgt tgtctttgga gcacaaaacc agttgaaaca
6241 tcaaattcgt ttgatgtact gaagtcagag gacgcgcagg gaatggataa tcttgcctgc
6301 gaagatctaa aaccagtctc tgaagaagta gtggaaaatc ctaccataca gaaagacgtt
6361 cttgagtgta atgtgaaaac taccgaagtt gtaggagaca ttatacttaa accagcaaat
6421 aatagtttaa aaattacaga agaggttggc cacacagatc taatggctgc ttatgtagac
6481 aattctagtc ttactattaa gaaacctaat gaattatcta gagtattagg tttgaaaacc
6541 cttgctactc atggtttagc tgctgttaat agtgtccctt gggatactat agctaattat
6601 gctaagcctt ttcttaacaa agttgttagt acaactacta acatagttac acggtgttta
6661 aaccgtgttt gtactaatta tatgccttat ttctttactt tattgctaca attgtgtact
6721 tttactagaa gtacaaattc tagaattaaa gcatctatgc cgactactat agcaaagaat
6781 actgttaaga gtgtcggtaa attttgtcta gaggcttcat ttaattattt gaagtcacct
6841 aatttttcta aactgataaa tattataatt tggtttttac tattaagtgt ttgcctaggt
6901 tctttaatct actcaaccgc tgctttaggt gttttaatgt ctaatttagg catgccttct
6961 tactgtactg gttacagaga aggctatttg aactctacta atgtcactat tgcaacctac
7021 tgtactggtt ctataccttg tagtgtttgt cttagtggtt tagattcttt agacacctat
7081 ccttctttag aaactataca aattaccatt tcatctttta aatgggattt aactgctttt
7141 ggcttagttg cagagtggtt tttggcatat attcttttca ctaggttttt ctatgtactt
7201 ggattggctg caatcatgca attgtttttc agctattttg cagtacattt tattagtaat
7261 tcttggctta tgtggttaat aattaatctt gtacaaatgg ccccgatttc agctatggtt
7321 agaatgtaca tcttctttgc atcattttat tatgtatgga aaagttatgt gcatgttgta
7381 gacggttgta attcatcaac ttgtatgatg tgttacaaac gtaatagagc aacaagagtc
7441 gaatgtacaa ctattgttaa tggtgttaga aggtcctttt atgtctatgc taatggaggt
7501 aaaggctttt gcaaactaca caattggaat tgtgttaatt gtgatacatt ctgtgctggt
7561 agtacattta ttagtgatga agttgcgaga gacttgtcac tacagtttaa aagaccaata
7621 aatcctactg accagtcttc ttacatcgtt gatagtgtta cagtgaagaa tggttccatc
7681 catctttact ttgataaagc tggtcaaaag acttatgaaa gacattctct ctctcatttt
7741 gttaacttag acaacctgag agctaataac actaaaggtt cattgcctat taatgttata
7801 gtttttgatg gtaaatcaaa atgtgaagaa tcatctgcaa aatcagcgtc tgtttactac
7861 agtcagctta tgtgtcaacc tatactgtta ctagatcagg cattagtgtc tgatgttggt
7921 gatagtgcgg aagttgcagt taaaatgttt gatgcttacg ttaatacgtt ttcatcaact
7981 tttaacgtac caatggaaaa actcaaaaca ctagttgcaa ctgcagaagc tgaacttgca
8041 aagaatgtgt ccttagacaa tgtcttatct acttttattt cagcagctcg gcaagggttt
8101 gttgattcag atgtagaaac taaagatgtt gttgaatgtc ttaaattgtc acatcaatct
8161 gacatagaag ttactggcga tagttgtaat aactatatgc tcacctataa caaagttgaa
8221 aacatgacac cccgtgacct tggtgcttgt attgactgta gtgcgcgtca tattaatgcg
8281 caggtagcaa aaagtcacaa cattgctttg atatggaacg ttaaagattt catgtcattg
8341 tctgaacaac tacgaaaaca aatacgtagt gctgctaaaa agaataactt accttttaag
8401 ttgacatgtg caactactag acaagttgtt aatgttgtaa caacaaagat agcacttaag
8461 ggtggtaaaa ttgttaataa ttggttgaag cagttaatta aagttacact tgtgttcctt
8521 tttgttgctg ctattttcta tttaataaca cctgttcatg tcatgtctaa acatactgac
8581 ttttcaagtg aaatcatagg atacaaggct attgatggtg gtgtcactcg tgacatagca
8641 tctacagata cttgttttgc taacaaacat gctgattttg acacatggtt tagccagcgt
8701 ggtggtagtt atactaatga caaagcttgc ccattgattg ctgcagtcat aacaagagaa
8761 gtgggttttg tcgtgcctgg tttgcctggc acgatattac gcacaactaa tggtgacttt
8821 ttgcatttct tacctagagt ttttagtgca gttggtaaca tctgttacac accatcaaaa
8881 cttatagagt acactgactt tgcaacatca gcttgtgttt tggctgctga atgtacaatt
8941 tttaaagatg cttctggtaa gccagtacca tattgttatg ataccaatgt actagaaggt
9001 tctgttgctt atgaaagttt acgccctgac acacgttatg tgctcatgga tggctctatt
9061 attcaatttc ctaacaccta ccttgaaggt tctgttagag tggtaacaac ttttgattct
9121 gagtactgta ggcacggcac ttgtgaaaga tcagaagctg gtgtttgtgt atctactagt
9181 ggtagatggg tacttaacaa tgattattac agatctttac caggagtttt ctgtggtgta
9241 gatgctgtaa atttacttac taatatgttt acaccactaa ttcaacctat tggtgctttg
9301 gacatatcag catctatagt agctggtggt attgtagcta tcgtagtaac atgccttgcc
9361 tactatttta tgaggtttag aagagctttt ggtgaataca gtcatgtagt tgcctttaat
9421 actttactat tccttatgtc attcactgta ctctgtttaa caccagttta ctcattctta
9481 cctggtgttt attctgttat ttacttgtac ttgacatttt atcttactaa tgatgtttct
9541 tttttagcac atattcagtg gatggttatg ttcacacctt tagtaccttt ctggataaca
9601 attgcttata tcatttgtat ttccacaaag catttctatt ggttctttag taattaccta
9661 aagagacgtg tagtctttaa tggtgtttcc tttagtactt ttgaagaagc tgcgctgtgc
9721 acctttttgt taaataaaga aatgtatcta aagttgcgta gtgatgtgct attacctctt
9781 acgcaatata atagatactt agctctttat aataagtaca agtattttag tggagcaatg
9841 gatacaacta gctacagaga agctgcttgt tgtcatctcg caaaggctct caatgacttc
9901 agtaactcag gttctgatgt tctttaccaa ccaccacaaa cctctatcac ctcagctgtt
9961 ttgcagagtg gttttagaaa aatggcattc ccatctggta aagttgaggg ttgtatggta
10021 caagtaactt gtggtacaac tacacttaac ggtctttggc ttgatgacgt agtttactgt
10081 ccaagacatg tgatctgcac ctctgaagac atgcttaacc ctaattatga agatttactc
10141 attcgtaagt ctaatcataa tttcttggta caggctggta atgttcaact cagggttatt
10201 ggacattcta tgcaaaattg tgtacttaag cttaaggttg atacagccaa tcctaagaca
10261 cctaagtata agtttgttcg cattcaacca ggacagactt tttcagtgtt agcttgttac
10321 aatggttcac catctggtgt ttaccaatgt gctatgaggc ccaatttcac tattaagggt
10381 tcattcctta atggttcatg tggtagtgtt ggttttaaca tagattatga ctgtgtctct
10441 ttttgttaca tgcaccatat ggaattacca actggagttc atgctggcac agacttagaa
10501 ggtaactttt atggaccttt tgttgacagg caaacagcac aagcagctgg tacggacaca
10561 actattacag ttaatgtttt agcttggttg tacgctgctg ttataaatgg agacaggtgg
10621 tttctcaatc gatttaccac aactcttaat gactttaacc ttgtggctat gaagtacaat
10681 tatgaacctc taacacaaga ccatgttgac atactaggac ctctttctgc tcaaactgga
10741 attgccgttt tagatatgtg tgcttcatta aaagaattac tgcaaaatgg tatgaatgga
10801 cgtaccatat tgggtagtgc tttattagaa gatgaattta caccttttga tgttgttaga
10861 caatgctcag gtgttacttt ccaaagtgca gtgaaaagaa caatcaaggg tacacaccac
10921 tggttgttac tcacaatttt gacttcactt ttagttttag tccagagtac tcaatggtct
10981 ttgttctttt ttttgtatga aaatgccttt ttaccttttg ctatgggtat tattgctatg
11041 tctgcttttg caatgatgtt tgtcaaacat aagcatgcat ttctctgttt gtttttgtta
11101 ccttctcttg ccactgtagc ttattttaat atggtctata tgcctgctag ttgggtgatg
11161 cgtattatga catggttgga tatggttgat actagtttgt ctggttttaa gctaaaagac
11221 tgtgttatgt atgcatcagc tgtagtgtta ctaatcctta tgacagcaag aactgtgtat
11281 gatgatggtg ctaggagagt gtggacactt atgaatgtct tgacactcgt ttataaagtt
11341 tattatggta atgctttaga tcaagccatt tccatgtggg ctcttataat ctctgttact
11401 tctaactact caggtgtagt tacaactgtc atgtttttgg ccagaggtat tgtttttatg
11461 tgtgttgagt attgccctat tttcttcata actggtaata cacttcagtg tataatgcta
11521 gtttattgtt tcttaggcta tttttgtact tgttactttg gcctcttttg tttactcaac
11581 cgctacttta gactgactct tggtgtttat gattacttag tttctacaca ggagtttaga
11641 tatatgaatt cacagggact actcccaccc aagaatagca tagatgcctt caaactcaac
11701 attaaattgt tgggtgttgg tggcaaacct tgtatcaaag tagccactgt acagtctaaa
11761 atgtcagatg taaagtgcac atcagtagtc ttactctcag ttttgcaaca actcagagta
11821 gaatcatcat ctaaattgtg ggctcaatgt gtccagttac acaatgacat tctcttagct
11881 aaagatacta ctgaagcctt tgaaaaaatg gtttcactac tttctgtttt gctttccatg
11941 cagggtgctg tagacataaa caagctttgt gaagaaatgc tggacaacag ggcaacctta
12001 caagctatag cctcagagtt tagttccctt ccatcatatg cagcttttgc tactgctcaa
12061 gaagcttatg agcaggctgt tgctaatggt gattctgaag ttgttcttaa aaagttgaag
12121 aagtctttga atgtggctaa atctgaattt gaccgtgatg cagccatgca acgtaagttg
12181 gaaaagatgg ctgatcaagc tatgacccaa atgtataaac aggctagatc tgaggacaag
12241 agggcaaaag ttactagtgc tatgcagaca atgcttttca ctatgcttag aaagttggat
12301 aatgatgcac tcaacaacat tatcaacaat gcaagagatg gttgtgttcc cttgaacata
12361 atacctctta caacagcagc caaactaatg gttgtcatac cagactataa cacatataaa
12421 aatacgtgtg atggtacaac atttacttat gcatcagcat tgtgggaaat ccaacaggtt
12481 gtagatgcag atagtaaaat tgttcaactt agtgaaatta gtatggacaa ttcacctaat
12541 ttagcatggc ctcttattgt aacagcttta agggccaatt ctgctgtcaa attacagaat
12601 aatgagctta gtcctgttgc actacgacag atgtcttgtg ctgccggtac tacacaaact
12661 gcttgcactg atgacaatgc gttagcttac tacaacacaa caaagggagg taggtttgta
12721 cttgcactgt tatccgattt acaggatttg aaatgggcta gattccctaa gagtgatgga
12781 actggtacta tctatacaga actggaacca ccttgtaggt ttgttacaga cacacctaaa
12841 ggtcctaaag tgaagtattt atactttatt aaaggattaa acaacctaaa tagaggtatg
12901 gtacttggta gtttagctgc cacagtacgt ctacaagctg gtaatgcaac agaagtgcct
12961 gccaattcaa ctgtattatc tttctgtgct tttgctgtag atgctgctaa agcttacaaa
13021 gattatctag ctagtggggg acaaccaatc actaattgtg ttaagatgtt gtgtacacac
13081 actggtactg gtcaggcaat aacagttaca ccggaagcca atatggatca agaatccttt
13141 ggtggtgcat cgtgttgtct gtactgccgt tgccacatag atcatccaaa tcctaaagga
13201 ttttgtgact taaaaggtaa gtatgtacaa atacctacaa cttgtgctaa tgaccctgtg
13261 ggttttacac ttaaaaacac agtctgtacc gtctgcggta tgtggaaagg ttatggctgt
13321 agttgtgatc aactccgcga acccatgctt cagtcagctg atgcacaatc gtttttaaac
13381 gggtttgcgg tgtaagtgca gcccgtctta caccgtgcgg cacaggcact agtactgatg
13441 tcgtatacag ggcttttgac atctacaatg ataaagtagc tggttttgct aaattcctaa
13501 aaactaattg ttgtcgcttc caagaaaagg acgaagatga caatttaatt gattcttact
13561 ttgtagttaa gagacacact ttctctaact accaacatga agaaacaatt tataatttac
13621 ttaaggattg tccagctgtt gctaaacatg acttctttaa gtttagaata gacggtgaca
13681 tggtaccaca tatatcacgt caacgtctta ctaaatacac aatggcagac ctcgtctatg
13741 ctttaaggca ttttgatgaa ggtaattgtg acacattaaa agaaatactt gtcacataca
13801 attgttgtga tgatgattat ttcaataaaa aggactggta tgattttgta gaaaacccag
13861 atatattacg cgtatacgcc aacttaggtg aacgtgtacg ccaagctttg ttaaaaacag
13921 tacaattctg tgatgccatg cgaaatgctg gtattgttgg tgtactgaca ttagataatc
13981 aagatctcaa tggtaactgg tatgatttcg gtgatttcat acaaaccacg ccaggtagtg
14041 gagttcctgt tgtagattct tattattcat tgttaatgcc tatattaacc ttgaccaggg
14101 ctttaactgc agagtcacat gttgacactg acttaacaaa gccttacatt aagtgggatt
14161 tgttaaaata tgacttcacg gaagagaggt taaaactctt tgaccgttat tttaaatatt
14221 gggatcagac ataccaccca aattgtgtta actgtttgga tgacagatgc attctgcatt
14281 gtgcaaactt taatgtttta ttctctacag tgttcccacc tacaagtttt ggaccactag
14341 tgagaaaaat atttgttgat ggtgttccat ttgtagtttc aactggatac cacttcagag
14401 agctaggtgt tgtacataat caggatgtaa acttacatag ctctagactt agttttaagg
14461 aattacttgt gtatgctgct gaccctgcta tgcacgctgc ttctggtaat ctattactag
14521 ataaacgcac tacgtgcttt tcagtagctg cacttactaa caatgttgct tttcaaactg
14581 tcaaacccgg taattttaac aaagacttct atgactttgc tgtgtctaag ggtttcttta
14641 aggaaggaag ttctgttgaa ttaaaacact tcttctttgc tcaggatggt aatgctgcta
14701 tcagcgatta tgactactat cgttataatc taccaacaat gtgtgatatc agacaactac
14761 tatttgtagt tgaagttgtt gataagtact ttgattgtta cgatggtggc tgtattaatg
14821 ctaaccaagt catcgtcaac aacctagaca aatcagctgg ttttccattt aataaatggg
14881 gtaaggctag actttattat gattcaatga gttatgagga tcaagatgca cttttcgcat
14941 atacaaaacg taatgtcatc cctactataa ctcaaatgaa tcttaagtat gccattagtg
15001 caaagaatag agctcgcacc gtagctggtg tctctatctg tagtactatg accaatagac
15061 agtttcatca aaaattattg aaatcaatag ccgccactag aggagctact gtagtaattg
15121 gaacaagcaa attctatggt ggttggcaca acatgttaaa aactgtttat agtgatgtag
15181 aaaaccctca ccttatgggt tgggattatc ctaaatgtga tagagccatg cctaacatgc
15241 ttagaattat ggcctcactt gttcttgctc gcaaacatac aacgtgttgt agcttgtcac
15301 accgtttcta tagattagct aatgagtgtg ctcaagtatt gagtgaaatg gtcatgtgtg
15361 gcggttcact atatgttaaa ccaggtggaa cctcatcagg agatgccaca actgcttatg
15421 ctaatagtgt ttttaacatt tgtcaagctg tcacggccaa tgttaatgca cttttatcta
15481 ctgatggtaa caaaattgcc gataagtatg tccgcaattt acaacacaga ctttatgagt
15541 gtctctatag aaatagagat gttgacacag actttgtgaa tgagttttac gcatatttgc
15601 gtaaacattt ctcaatgatg atactctctg acgatgctgt tgtgtgtttc aatagcactt
15661 atgcatctca aggtctagtg gctagcataa agaactttaa gtcagttctt tattatcaaa
15721 acaatgtttt tatgtctgaa gcaaaatgtt ggactgagac tgaccttact aaaggacctc
15781 atgaattttg ctctcaacat acaatgctag ttaaacaggg tgatgattat gtgtaccttc
15841 cttacccaga tccatcaaga atcctagggg ccggctgttt tgtagatgat atcgtaaaaa
15901 cagatggtac acttatgatt gaacggttcg tgtctttagc tatagatgct tacccactta
15961 ctaaacatcc taatcaggag tatgctgatg tctttcattt gtacttacaa tacataagaa
16021 agctacatga tgagttaaca ggacacatgt tagacatgta ttctgttatg cttactaatg
16081 ataacacttc aaggtattgg gaacctgagt tttatgaggc tatgtacaca ccgcatacag
16141 tcttacaggc tgttggggct tgtgttcttt gcaattcaca gacttcatta agatgtggtg
16201 cttgcatacg tagaccattc ttatgttgta aatgctgtta cgaccatgtc atatcaacat
16261 cacataaatt agtcttgtct gttaatccgt atgtttgcaa tgctccaggt tgtgatgtca
16321 cagatgtgac tcaactttac ttaggaggta tgagctatta ttgtaaatca cataaaccac
16381 ccattagttt tccattgtgt gctaatggac aagtttttgg tttatataaa aatacatgtg
16441 ttggtagcga taatgttact gactttaatg caattgcaac atgtgactgg acaaatgctg
16501 gtgattacat tttagctaac acctgtactg aaagactcaa gctttttgca gcagaaacgc
16561 tcaaagctac tgaggagaca tttaaactgt cttatggtat tgctactgta cgtgaagtgc
16621 tgtctgacag agaattacat ctttcatggg aagttggtaa acctagacca ccacttaacc
16681 gaaattatgt ctttactggt tatcgtgtaa ctaaaaacag taaagtacaa ataggagagt
16741 acacctttga aaaaggtgac tatggtgatg ctgttgttta ccgaggtaca acaacttaca
16801 aattaaatgt tggtgattat tttgtgctga catcacatac agtaatgcca ttaagtgcac
16861 ctacactagt gccacaagag cactatgtta gaattactgg cttataccca acactcaata
16921 tctcagatga gttttctagc aatgttgcaa attatcaaaa ggttggtatg caaaagtatt
16981 ctacactcca gggaccacct ggtactggta agagtcattt tgctattggc ctagctctct
17041 actacccttc tgctcgcata gtgtatacag cttgctctca tgccgctgtt gatgcactat
17101 gtgagaaggc attaaaatat ttgcctatag ataaatgtag tagaattata cctgcacgtg
17161 ctcgtgtaga gtgttttgat aaattcaaag tgaattcaac attagaacag tatgtctttt
17221 gtactgtaaa tgcattgcct gagacgacag cagatatagt tgtctttgat gaaatttcaa
17281 tggccacaaa ttatgatttg agtgttgtca atgccagatt acgtgctaag cactatgtgt
17341 acattggcga ccctgctcaa ttacctgcac cacgcacatt gctaactaag ggcacactag
17401 aaccagaata tttcaattca gtgtgtagac ttatgaaaac tataggtcca gacatgttcc
17461 tcggaacttg tcggcgttgt cctgctgaaa ttgttgacac tgtgagtgct ttggtttatg
17521 ataataagct taaagcacat aaagacaaat cagctcaatg ctttaaaatg ttttataagg
17581 gtgttatcac gcatgatgtt tcatctgcaa ttaacaggcc acaaataggc gtggtaagag
17641 aattccttac acgtaaccct gcttggagaa aagctgtctt tatttcacct tataattcac
17701 agaatgctgt agcctcaaag attttgggac taccaactca aactgttgat tcatcacagg
17761 gctcagaata tgactatgtc atattcactc aaaccactga aacagctcac tcttgtaatg
17821 taaacagatt taatgttgct attaccagag caaaagtagg catactttgc ataatgtctg
17881 atagagacct ttatgacaag ttgcaattta caagtcttga aattccacgt aggaatgtgg
17941 caactttaca agctgaaaat gtaacaggac tctttaaaga ttgtagtaag gtaatcactg
18001 ggttacatcc tacacaggca cctacacacc tcagtgttga cactaaattc aaaactgaag
18061 gtttatgtgt tgacatacct ggcataccta aggacatgac ctatagaaga ctcatctcta
18121 tgatgggttt taaaatgaat tatcaagtta atggttaccc taacatgttt atcacccgcg
18181 aagaagctat aagacatgta cgtgcatgga ttggcttcga tgtcgagggg tgtcatgcta
18241 ctagagaagc tgttggtacc aatttacctt tacagctagg tttttctaca ggtgttaacc
18301 tagttgctgt acctacaggt tatgttgata cacctaataa tacagatttt tccagagtta
18361 gtgctaaacc accgcctgga gatcaattta aacacctcat accacttatg tacaaaggac
18421 ttccttggaa tgtagtgcgt ataaagattg tacaaatgtt aagtgacaca cttaaaaatc
18481 tctctgacag agtcgtattt gtcttatggg cacatggctt tgagttgaca tctatgaagt
18541 attttgtgaa aataggacct gagcgcacct gttgtctatg tgatagacgt gccacatgct
18601 tttccactgc ttcagacact tatgcctgtt ggcatcattc tattggattt gattacgtct
18661 ataatccgtt tatgattgat gttcaacaat ggggttttac aggtaaccta caaagcaacc
18721 atgatctgta ttgtcaagtc catggtaatg cacatgtagc tagttgtgat gcaatcatga
18781 ctaggtgtct agctgtccac gagtgctttg ttaagcgtgt tgactggact attgaatatc
18841 ctataattgg tgatgaactg aagattaatg cggcttgtag aaaggttcaa cacatggttg
18901 ttaaagctgc attattagca gacaaattcc cagttcttca cgacattggt aaccctaaag
18961 ctattaagtg tgtacctcaa gctgatgtag aatggaagtt ctatgatgca cagccttgta
19021 gtgacaaagc ttataaaata gaagaattat tctattctta tgccacacat tctgacaaat
19081 tcacagatgg tgtatgccta ttttggaatt gcaatgtcga tagatatcct gctaattcca
19141 ttgtttgtag atttgacact agagtgctat ctaaccttaa cttgcctggt tgtgatggtg
19201 gcagtttgta tgtaaataaa catgcattcc acacaccagc ttttgataaa agtgcttttg
19261 ttaatttaaa acaattacca tttttctatt actctgacag tccatgtgag tctcatggaa
19321 aacaagtagt gtcagatata gattatgtac cactaaagtc tgctacgtgt ataacacgtt
19381 gcaatttagg tggtgctgtc tgtagacatc atgctaatga gtacagattg tatctcgatg
19441 cttataacat gatgatctca gctggcttta gcttgtgggt ttacaaacaa tttgatactt
19501 ataacctctg gaacactttt acaagacttc agagtttaga aaatgtggct tttaatgttg
19561 taaataaggg acactttgat ggacaacagg gtgaagtacc agtttctatc attaataaca
19621 ctgtttacac aaaagttgat ggtgttgatg tagaattgtt tgaaaataaa acaacattac
19681 ctgttaatgt agcatttgag ctttgggcta agcgcaacat taaaccagta ccagaggtga
19741 aaatactcaa taatttgggt gtggacattg ctgctaatac tgtgatctgg gactacaaaa
19801 gagatgctcc agcacatata tctactattg gtgtttgttc tatgactgac atagccaaga
19861 aaccaactga aacgatttgt gcaccactca ctgtcttttt tgatggtaga gttgatggtc
19921 aagtagactt atttagaaat gcccgtaatg gtgttcttat tacagaaggt agtgttaaag
19981 gtttacaacc atctgtaggt cccaaacaag ctagtcttaa tggagtcaca ttaattggag
20041 aagccgtaaa aacacagttc aattattata agaaagttga tggtgttgtc caacaattac
20101 ctgaaactta ctttactcag agtagaaatt tacaagaatt taaacccagg agtcaaatgg
20161 aaattgattt cttagaatta gctatggatg aattcattga acggtataaa ttagaaggct
20221 atgccttcga acatatcgtt tatggagatt ttagtcatag tcagttaggt ggtttacatc
20281 tactgattgg actagctaaa cgttttaagg aatcaccttt tgaattagaa gattttattc
20341 ctatggacag tacagttaaa aactatttca taacagatgc gcaaacaggt tcatctaagt
20401 gtgtgtgttc tgttattgat ttattacttg atgattttgt tgaaataata aaatcccaag
20461 atttatctgt agtttctaag gttgtcaaag tgactattga ctatacagaa atttcattta
20521 tgctttggtg taaagatggc catgtagaaa cattttaccc aaaattacaa tctagtcaag
20581 cgtggcaacc gggtgttgct atgcctaatc tttacaaaat gcaaagaatg ctattagaaa
20641 agtgtgacct tcaaaattat ggtgatagtg caacattacc taaaggcata atgatgaatg
20701 tcgcaaaata tactcaactg tgtcaatatt taaacacatt aacattagct gtaccctata
20761 atatgagagt tatacatttt ggtgctggtt ctgataaagg agttgcacca ggtacagctg
20821 ttttaagaca gtggttgcct acgggtacgc tgcttgtcga ttcagatctt aatgactttg
20881 tctctgatgc agattcaact ttgattggtg attgtgcaac tgtacataca gctaataaat
20941 gggatctcat tattagtgat atgtacgacc ctaagactaa aaatgttaca aaagaaaatg
21001 actctaaaga gggttttttc acttacattt gtgggtttat acaacaaaag ctagctcttg
21061 gaggttccgt ggctataaag ataacagaac attcttggaa tgctgatctt tataagctca
21121 tgggacactt cgcatggtgg acagcctttg ttactaatgt gaatgcgtca tcatctgaag
21181 catttttaat tggatgtaat tatcttggca aaccacgcga acaaatagat ggttatgtca
21241 tgcatgcaaa ttacatattt tggaggaata caaatccaat tcagttgtct tcctattctt
21301 tatttgacat gagtaaattt ccccttaaat taaggggtac tgctgttatg tctttaaaag
21361 aaggtcaaat caatgatatg attttatctc ttcttagtaa aggtagactt ataattagag
21421 aaaacaacag agttgttatt tctagtgatg ttcttgttaa caactaaacg aacaatgttt
21481 gtttttcttg ttttattgcc actagtctct agtcagtgtg ttaatcttac aaccagaact
21541 caattacccc ctgcatacac taattctttc acacgtggtg tttattaccc tgacaaagtt
21601 ttcagatcct cagttttaca ttcaactcag gacttgttct tacctttctt ttccaatgtt
21661 acttggttcc atgctataca tgtctctggg accaatggta ctaagaggtt tgataaccct
21721 gtcctaccat ttaatgatgg tgtttatttt gcttccactg agaagtctaa cataataaga
21781 ggctggattt ttggtactac tttagattcg aagacccagt ccctacttat tgttaataac
21841 gctactaatg ttgttattaa agtctgtgaa tttcaatttt gtaatgatcc atttttgggt
21901 gtttattacc acaaaaacaa caaaagttgg atggaaagtg agttcagagt ttattctagt
21961 gcgaataatt gcacttttga atatgtctct cagccttttc ttatggacct tgaaggaaaa
22021 cagggtaatt tcaaaaatct tagggaattt gtgtttaaga atattgatgg ttattttaaa
22081 atatattcta agcacacgcc tattaattta gtgcgtgatc tccctcaggg tttttcggct
22141 ttagaaccat tggtagattt gccaataggt attaacatca ctaggtttca aactttactt
22201 gctttacata gaagttattt gactcctggt gattcttctt caggttggac agctggtgct
22261 gcagcttatt atgtgggtta tcttcaacct aggacttttc tattaaaata taatgaaaat
22321 ggaaccatta cagatgctgt agactgtgca cttgaccctc tctcagaaac aaagtgtacg
22381 ttgaaatcct tcactgtaga aaaaggaatc tatcaaactt ctaactttag agtccaacca
22441 acagaatcta ttgttagatt tcctaatatt acaaacttgt gcccttttgg tgaagttttt
22501 aacgccacca gatttgcatc tgtttatgct tggaacagga agagaatcag caactgtgtt
22561 gctgattatt ctgtcctata taattccgca tcattttcca cttttaagtg ttatggagtg
22621 tctcctacta aattaaatga tctctgcttt actaatgtct atgcagattc atttgtaatt
22681 agaggtgatg aagtcagaca aatcgctcca gggcaaactg gaaagattgc tgattataat
22741 tataaattac cagatgattt tacaggctgc gttatagctt ggaattctaa caatcttgat
22801 tctaaggttg gtggtaatta taattacctg tatagattgt ttaggaagtc taatctcaaa
22861 ccttttgaga gagatatttc aactgaaatc tatcaggccg gtagcacacc ttgtaatggt
22921 gttgaaggtt ttaattgtta ctttccttta caatcatatg gtttccaacc cactaatggt
22981 gttggttacc aaccatacag agtagtagta ctttcttttg aacttctaca tgcaccagca
23041 actgtttgtg gacctaaaaa gtctactaat ttggttaaaa acaaatgtgt caatttcaac
23101 ttcaatggtt taacaggcac aggtgttctt actgagtcta acaaaaagtt tctgcctttc
23161 caacaatttg gcagagacat tgctgacact actgatgctg tccgtgatcc acagacactt
23221 gagattcttg acattacacc atgttctttt ggtggtgtca gtgttataac accaggaaca
23281 aatacttcta accaggttgc tgttctttat caggatgtta actgcacaga agtccctgtt
23341 gctattcatg cagatcaact tactcctact tggcgtgttt attctacagg ttctaatgtt
23401 tttcaaacac gtgcaggctg tttaataggg gctgaacatg tcaacaactc atatgagtgt
23461 gacataccca ttggtgcagg tatatgcgct agttatcaga ctcagactaa ttctcctcgg
23521 cgggcacgta gtgtagctag tcaatccatc attgcctaca ctatgtcact tggtgcagaa
23581 aattcagttg cttactctaa taactctatt gccataccca caaattttac tattagtgtt
23641 accacagaaa ttctaccagt gtctatgacc aagacatcag tagattgtac aatgtacatt
23701 tgtggtgatt caactgaatg cagcaatctt ttgttgcaat atggcagttt ttgtacacaa
23761 ttaaaccgtg ctttaactgg aatagctgtt gaacaagaca aaaacaccca agaagttttt
23821 gcacaagtca aacaaattta caaaacacca ccaattaaag attttggtgg ttttaatttt
23881 tcacaaatat taccagatcc atcaaaacca agcaagaggt catttattga agatctactt
23941 ttcaacaaag tgacacttgc agatgctggc ttcatcaaac aatatggtga ttgccttggt
24001 gatattgctg ctagagacct catttgtgca caaaagttta acggccttac tgttttgcca
24061 cctttgctca cagatgaaat gattgctcaa tacacttctg cactgttagc gggtacaatc
24121 acttctggtt ggacctttgg tgcaggtgct gcattacaaa taccatttgc tatgcaaatg
24181 gcttataggt ttaatggtat tggagttaca cagaatgttc tctatgagaa ccaaaaattg
24241 attgccaacc aatttaatag tgctattggc aaaattcaag actcactttc ttccacagca
24301 agtgcacttg gaaaacttca agatgtggtc aaccaaaatg cacaagcttt aaacacgctt
24361 gttaaacaac ttagctccaa ttttggtgca atttcaagtg ttttaaatga tatcctttca
24421 cgtcttgaca aagttgaggc tgaagtgcaa attgataggt tgatcacagg cagacttcaa
24481 agtttgcaga catatgtgac tcaacaatta attagagctg cagaaatcag agcttctgct
24541 aatcttgctg ctactaaaat gtcagagtgt gtacttggac aatcaaaaag agttgatttt
24601 tgtggaaagg gctatcatct tatgtccttc cctcagtcag cacctcatgg tgtagtcttc
24661 ttgcatgtga cttatgtccc tgcacaagaa aagaacttca caactgctcc tgccatttgt
24721 catgatggaa aagcacactt tcctcgtgaa ggtgtctttg tttcaaatgg cacacactgg
24781 tttgtaacac aaaggaattt ttatgaacca caaatcatta ctacagacaa cacatttgtg
24841 tctggtaact gtgatgttgt aataggaatt gtcaacaaca cagtttatga tcctttgcaa
24901 cctgaattag actcattcaa ggaggagtta gataaatatt ttaagaatca tacatcacca
24961 gatgttgatt taggtgacat ctctggcatt aatgcttcag ttgtaaacat tcaaaaagaa
25021 attgaccgcc tcaatgaggt tgccaagaat ttaaatgaat ctctcatcga tctccaagaa
25081 cttggaaagt atgagcagta tataaaatgg ccatggtaca tttggctagg ttttatagct
25141 ggcttgattg ccatagtaat ggtgacaatt atgctttgct gtatgaccag ttgctgtagt
25201 tgtctcaagg gctgttgttc ttgtggatcc tgctgcaaat ttgatgaaga cgactctgag
25261 ccagtgctca aaggagtcaa attacattac acataaacga acttatggat ttgtttatga
25321 gaatcttcac aattggaact gtaactttga agcaaggtga aatcaaggat gctactcctt
25381 cagattttgt tcgcgctact gcaacgatac cgatacaagc ctcactccct ttcggatggc
25441 ttattgttgg cgttgcactt cttgctgttt ttcagagcgc ttccaaaatc ataaccctca
25501 aaaagagatg gcaactagca ctctccaagg gtgttcactt tgtttgcaac ttgctgttgt
25561 tgtttgtaac agtttactca caccttttgc tcgttgctgc tggccttgaa gccccttttc
25621 tctatcttta tgctttagtc tacttcttgc agagtataaa ctttgtaaga ataataatga
25681 ggctttggct ttgctggaaa tgccgttcca aaaacccatt actttatgat gccaactatt
25741 ttctttgctg gcatactaat tgttacgact attgtatacc ttacaatagt gtaacttctt
25801 caattgtcat tacttcaggt gatggcacaa caagtcctat ttctgaacat gactaccaga
25861 ttggtggtta tactgaaaaa tgggaatctg gagtaaaaga ctgtgttgta ttacacagtt
25921 acttcacttc agactattac cagctgtact caactcaatt gagtacagac actggtgttg
25981 aacatgttac cttcttcatc tacaataaaa ttgttgatga gcctgaagaa catgtccaaa
26041 ttcacacaat cgacggttca tccggagttg ttaatccagt aatggaacca atttatgatg
26101 aaccgacgac gactactagc gtgcctttgt aagcacaagc tgatgagtac gaacttatgt
26161 actcattcgt ttcggaagag acaggtacgt taatagttaa tagcgtactt ctttttcttg
26221 ctttcgtggt attcttgcta gttacactag ccatccttac tgcgcttcga ttgtgtgcgt
26281 actgctgcaa tattgttaac gtgagtcttg taaaaccttc tttttacgtt tactctcgtg
26341 ttaaaaatct gaattcttct agagttcctg atcttctggt ctaaacgaac taaatattat
26401 attagttttt ctgtttggaa ctttaatttt agccatggca gattccaacg gtactattac
26461 cgttgaagag cttaaaaagc tccttgaaca atggaaccta gtaataggtt tcctattcct
26521 tacatggatt tgtcttctac aatttgccta tgccaacagg aataggtttt tgtatataat
26581 taagttaatt ttcctctggc tgttatggcc agtaacttta gcttgttttg tgcttgctgc
26641 tgtttacaga ataaattgga tcaccggtgg aattgctatc gcaatggctt gtcttgtagg
26701 cttgatgtgg ctcagctact tcattgcttc tttcagactg tttgcgcgta cgcgttccat
26761 gtggtcattc aatccagaaa ctaacattct tctcaacgtg ccactccatg gcactattct
26821 gaccagaccg cttctagaaa gtgaactcgt aatcggagct gtgatccttc gtggacatct
26881 tcgtattgct ggacaccatc taggacgctg tgacatcaag gacctgccta aagaaatcac
26941 tgttgctaca tcacgaacgc tttcttatta caaattggga gcttcgcagc gtgtagcagg
27001 tgactcaggt tttgctgcat acagtcgcta caggattggc aactataaat taaacacaga
27061 ccattccagt agcagtgaca atattgcttt gcttgtacag taagtgacaa cagatgtttc
27121 atctcgttga ctttcaggtt actatagcag agatattact aattattatg aggactttta
27181 aagtttccat ttggaatctt gattacatca taaacctcat aattaaaaat ttatctaagt
27241 cactaactga gaataaatat tctcaattag atgaagagca accaatggag attgattaaa
27301 cgaacatgaa aattattctt ttcttggcac tgataacact cgctacttgt gagctttatc
27361 actaccaaga gtgtgttaga ggtacaacag tacttttaaa agaaccttgc tcttctggaa
27421 catacgaggg caattcacca tttcatcctc tagctgataa caaatttgca ctgacttgct
27481 ttagcactca atttgctttt gcttgtcctg acggcgtaaa acacgtctat cagttacgtg
27541 ccagatcagt ttcacctaaa ctgttcatca gacaagagga agttcaagaa ctttactctc
27601 caatttttct tattgttgcg gcaatagtgt ttataacact ttgcttcaca ctcaaaagaa
27661 agacagaatg attgaacttt cattaattga cttctatttg tgctttttag cctttctgct
27721 attccttgtt ttaattatgc ttattatctt ttggttctca cttgaactgc aagatcataa
27781 tgaaacttgt cacgcctaaa cgaacatgaa atttcttgtt ttcttaggaa tcatcacaac
27841 tgtagctgca tttcaccaag aatgtagttt acagtcatgt actcaacatc aaccatatgt
27901 agttgatgac ccgtgtccta ttcacttcta ttctaaatgg tatattagag taggagctag
27961 aaaatcagca cctttaattg aattgtgcgt ggatgaggct ggttctaaat cacccattca
28021 gtacatcgat atcggtaatt atacagtttc ctgtttacct tttacaatta attgccagga
28081 acctaaattg ggtagtcttg tagtgcgttg ttcgttctat gaagactttt tagagtatca
28141 tgacgttcgt gttgttttag atttcatcta aacgaacaaa ctaaaatgtc tgataatgga
28201 ccccaaaatc agcgaaatgc accccgcatt acgtttggtg gaccctcaga ttcaactggc
28261 agtaaccaga atggagaacg cagtggggcg cgatcaaaac aacgtcggcc ccaaggttta
28321 cccaataata ctgcgtcttg gttcaccgct ctcactcaac atggcaagga agaccttaaa
28381 ttccctcgag gacaaggcgt tccaattaac accaatagca gtccagatga ccaaattggc
28441 tactaccgaa gagctaccag acgaattcgt ggtggtgacg gtaaaatgaa agatctcagt
28501 ccaagatggt atttctacta cctaggaact gggccagaag ctggacttcc ctatggtgct
28561 aacaaagacg gcatcatatg ggttgcaact gagggagcct tgaatacacc aaaagatcac
28621 attggcaccc gcaatcctgc taacaatgct gcaatcgtgc tacaacttcc tcaaggaaca
28681 acattgccaa aaggcttcta cgcagaaggg agcagaggcg gcagtcaagc ctcttctcgt
28741 tcctcatcac gtagtcgcaa cagttcaaga aattcaactc caggcagcag taggggaact
28801 tctcctgcta gaatggctgg caatggcggt gatgctgctc ttgctttgct gctgcttgac
28861 agattgaacc agcttgagag caaaatgtct ggtaaaggcc aacaacaaca aggccaaact
28921 gtcactaaga aatctgctgc tgaggcttct aagaagcctc ggcaaaaacg tactgccact
28981 aaagcataca atgtaacaca agctttcggc agacgtggtc cagaacaaac ccaaggaaat
29041 tttggggacc aggaactaat cagacaagga actgattaca aacattggcc gcaaattgca
29101 caatttgccc ccagcgcttc agcgttcttc ggaatgtcgc gcattggcat ggaagtcaca
29161 ccttcgggaa cgtggttgac ctacacaggt gccatcaaat tggatgacaa agatccaaat
29221 ttcaaagatc aagtcatttt gctgaataag catattgacg catacaaaac attcccacca
29281 acagagccta aaaaggacaa aaagaagaag gctgatgaaa ctcaagcctt accgcagaga
29341 cagaagaaac agcaaactgt gactcttctt cctgctgcag atttggatga tttctccaaa
29401 caattgcaac aatccatgag cagtgctgac tcaactcagg cctaaactca tgcagaccac
29461 acaaggcaga tgggctatat aaacgttttc gcttttccgt ttacgatata tagtctactc
29521 ttgtgcagaa tgaattctcg taactacata gcacaagtag atgtagttaa ctttaatctc
29581 acatagcaat ctttaatcag tgtgtaacat tagggaggac ttgaaagagc caccacattt
29641 tcaccgaggc cacgcggagt acgatcgagt gtacagtgaa caatgctagg gagagctgcc
29701 tatatggaag agccctaatg tgtaaaatta attttagtag tgctatcccc atgtgatttt
29761 aatagcttct tagg
//
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