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#!/usr/bin/python
'''
pysam
*****
'''
import os, sys, glob, shutil, hashlib, re, fnmatch
import platform
name = "pysam"
IS_PYTHON3 = sys.version_info[0] >= 3
# collect pysam version
sys.path.insert( 0, "pysam")
import version
version = version.__version__
samtools_exclude = ( "bamtk.c", "razip.c", "bgzip.c",
"main.c", "calDepth.c", "bam2bed.c",
"wgsim.c", "md5fa.c", "maq2sam.c",
"bamcheck.c",
"chk_indel.c" )
samtools_dest = os.path.abspath( "samtools" )
tabix_exclude = ( "main.c", )
tabix_dest = os.path.abspath( "tabix" )
def locate(pattern, root=os.curdir):
'''Locate all files matching supplied filename pattern in and below
supplied root directory.'''
for path, dirs, files in os.walk(os.path.abspath(root)):
for filename in fnmatch.filter(files, pattern):
yield os.path.join(path, filename)
def _update_pysam_files(cf, destdir):
'''update pysam files applying redirection of ouput'''
for filename in cf:
if not filename: continue
dest = filename + ".pysam.c"
with open( filename ) as infile:
with open( dest, "w" ) as outfile:
outfile.write( '#include "pysam.h"\n\n' )
outfile.write( re.sub( "stderr", "pysamerr", "".join(infile.readlines()) ) )
with open( os.path.join( destdir, "pysam.h" ), "w" )as outfile:
outfile.write ("""#ifndef PYSAM_H
#define PYSAM_H
#include "stdio.h"
extern FILE * pysamerr;
#endif
""")
# copy samtools source
if len(sys.argv) >= 2 and sys.argv[1] == "import":
if len(sys.argv) < 3: raise ValueError("missing PATH to samtools source directory")
if len(sys.argv) < 4: raise ValueError("missing PATH to tabix source directory")
for destdir, srcdir, exclude in zip(
(samtools_dest, tabix_dest),
sys.argv[2:4],
(samtools_exclude, tabix_exclude)):
srcdir = os.path.abspath( srcdir )
if not os.path.exists( srcdir ): raise IOError( "samtools src dir `%s` does not exist." % srcdir )
cfiles = locate( "*.c", srcdir )
hfiles = locate( "*.h", srcdir )
ncopied = 0
def _compareAndCopy( src, srcdir, destdir, exclude ):
d, f = os.path.split(src)
if f in exclude: return None
common_prefix = os.path.commonprefix( (d, srcdir ) )
subdir = re.sub( common_prefix, "", d )[1:]
targetdir = os.path.join( destdir, subdir )
if not os.path.exists( targetdir ):
os.makedirs( targetdir )
old_file = os.path.join( targetdir, f )
if os.path.exists( old_file ):
md5_old = hashlib.md5("".join(open(old_file,"r").readlines())).digest()
md5_new = hashlib.md5("".join(open(src,"r").readlines())).digest()
if md5_old != md5_new:
raise ValueError( "incompatible files for %s and %s" % (old_file, src ))
shutil.copy( src, targetdir )
return old_file
for src_file in hfiles:
_compareAndCopy( src_file, srcdir,destdir, exclude )
ncopied += 1
cf = []
for src_file in cfiles:
cf.append( _compareAndCopy( src_file, srcdir, destdir, exclude ) )
ncopied += 1
sys.stdout.write("installed latest source code from %s: %i files copied" % (srcdir, ncopied))
# redirect stderr to pysamerr and replace bam.h with a stub.
sys.stdout.write("applying stderr redirection")
_update_pysam_files(cf, destdir)
sys.exit(0)
if len(sys.argv) >= 2 and sys.argv[1] == "refresh":
sys.stdout.write("refreshing latest source code from .c to .pysam.c")
# redirect stderr to pysamerr and replace bam.h with a stub.
sys.stdout.write("applying stderr redirection")
for destdir in ('samtools', 'tabix'):
pysamcfiles = locate( "*.pysam.c", destdir )
for f in pysamcfiles: os.remove(f)
cfiles = locate( "*.c", destdir )
_update_pysam_files(cfiles, destdir)
sys.exit(0)
###################
# populate headers
# mkdir pysam/include pysam/include/win32
# touch pysam/include/__init__.py pysam/include/win32/__init__.py
# cp samtools/*.h pysam/*.h pysam/include
# cp samtools/win32/*.h pysam/include/win32
try:
from setuptools import Extension, setup, find_packages
except ImportError:
#from ez_setup import use_setuptools
#use_setuptools()
from setuptools import Extension, setup, find_packages
#######################################################
#######################################################
try:
from Cython.Distutils import build_ext
except ImportError:
# no Cython available - use existing C code
cmdclass = { }
csamtools_sources = [ "pysam/csamtools.c" ]
tabix_sources = [ "pysam/ctabix.c" ]
tabproxies_sources = ["pysam/TabProxies.c" ]
cvcf_sources = ["pysam/cvcf.c" ]
else:
# remove existing files to recompute
# necessary to be both compatible for python 2.7 and 3.3
if IS_PYTHON3:
for f in ( "pysam/csamtools.c",
"pysam/ctabix.c",
"pysam/TabProxies.c",
"pysam/cvcf.c" ):
try:
os.unlink( f )
except:
pass
cmdclass = { 'build_ext' : build_ext }
csamtools_sources = [ "pysam/csamtools.pyx" ]
tabix_sources = [ "pysam/ctabix.pyx" ]
tabproxies_sources = ["pysam/TabProxies.pyx" ]
cvcf_sources = ["pysam/cvcf.pyx" ]
#######################################################
classifiers = """
Development Status :: 2 - Alpha
Operating System :: MacOS :: MacOS X
Operating System :: Microsoft :: Windows :: Windows NT/2000
Operating System :: OS Independent
Operating System :: POSIX
Operating System :: POSIX :: Linux
Operating System :: Unix
Programming Language :: Python
Topic :: Scientific/Engineering
Topic :: Scientific/Engineering :: Bioinformatics
"""
#######################################################
## Windows compatibility
if platform.system()=='Windows':
include_os = ['win32']
os_c_files = ['win32/getopt.c']
else:
include_os = []
os_c_files = []
#######################################################
samtools = Extension(
"pysam.csamtools",
csamtools_sources +\
[ "pysam/%s" % x for x in (
"pysam_util.c", )] +\
glob.glob( os.path.join( "samtools", "*.pysam.c" )) +\
os_c_files + \
glob.glob( os.path.join( "samtools", "*", "*.pysam.c" ) ),
library_dirs=[],
include_dirs=[ "samtools", "pysam" ] + include_os,
libraries=[ "z", ],
language="c",
define_macros = [('_FILE_OFFSET_BITS','64'),
('_USE_KNETFILE','')],
)
tabix = Extension(
"pysam.ctabix",
tabix_sources +\
[ "pysam/%s" % x for x in ( "tabix_util.c", )] +\
os_c_files + \
glob.glob( os.path.join( "tabix", "*.pysam.c" ) ),
library_dirs=[],
include_dirs=[ "tabix", "pysam" ] + include_os,
libraries=[ "z", ],
language="c",
define_macros = [('_FILE_OFFSET_BITS','64'),
('_USE_KNETFILE','')],
)
tabproxies = Extension(
"pysam.TabProxies",
tabproxies_sources + os_c_files,
library_dirs=[],
include_dirs= include_os,
libraries=[ "z", ],
language="c",
)
cvcf = Extension(
"pysam.cvcf",
cvcf_sources + os_c_files,
library_dirs=[],
include_dirs= ["tabix",] + include_os,
libraries=[ "z", ],
language="c",
)
metadata = {
'name': name,
'version': version,
'description': "pysam",
'long_description': __doc__,
'author': "Andreas Heger",
'author_email': "andreas.heger@gmail.com",
'license': "MIT",
'platforms': "ALL",
'url': "http://code.google.com/p/pysam/",
'packages' : ['pysam',
'pysam.include',
'pysam.include.samtools',
'pysam.include.samtools.bcftools',
'pysam.include.samtools.win32',
'pysam.include.tabix'],
'requires' : ['cython (>=0.17)'],
'ext_modules': [samtools, tabix, tabproxies, cvcf ],
'cmdclass' : cmdclass,
'install_requires' : ['cython>=0.17',],
'package_dir' : { 'pysam' : 'pysam',
'pysam.include.samtools' : 'samtools',
'pysam.include.tabix' : 'tabix' },
'package_data' : { '' : ['*.pxd', '*.h'], },
# do not pack in order to permit linking to csamtools.so
'zip_safe' :False,
'use_2to3': True,
}
if __name__=='__main__':
dist = setup(**metadata)
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