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c By R Gray, March 19, 2000, DFCI
c Copyright (C) 2000 Robert Gray
c Distributed under the GNU public license
c
c t-statistics
c first ng1 columns of d assumed to be group 1, other ng-ng1 assumed to be
c group2. Note: single precision stats
c
c Modified by R. Gentleman, 2004, just extracted the ttest stats and
c computed a ratio on demand - or fold-change
subroutine fastt(d,n,ng,ng1,z,dm,eqv,ratio)
real d(n,ng),z(n),dm(n)
integer n,ng,ng1,ng2,eqv,ratio
c initialize
ng2=ng-ng1
do 61 i=1,n
call tst2GM(d(i,1),ng1,ng2,n,z(i),dm(i), eqv, ratio)
61 continue
return
end
subroutine tst2GM(d,ng1,ng2,n,tst,dm,eqv, ratio)
c columns 1 to ng1 in group 1, ng1+1 to ng1+ng2 in group 2
real d(n,ng1+ng2),tst,dm
double precision dm1,dm2,dss1,dss2
integer ng1,ng2,n,i,eqv, ratio
dm1=0
dm2=0
dss1=0
dss2=0
do 10 i=1,ng1
dm1=dm1+d(1,i)
10 continue
dm1=dm1/ng1
do 11 i=1,ng1
dss1=dss1+(d(1,i)-dm1)**2
11 continue
do 12 i=1,ng2
dm2=dm2+d(1,ng1+i)
12 continue
dm2=dm2/ng2
do 13 i=1,ng2
dss2=dss2+(d(1,ng1+i)-dm2)**2
13 continue
if( ratio.eq.0) then
dm=dm1-dm2
endif
if( ratio.eq.1) then
dm=dm1/dm2
endif
if (dss1.eq.0.and.dss2.eq.0) then
tst=0
return
endif
c intermediate calculations in dp, so stats with many ties give same sp result
c regardless of order of calculations
if( eqv .eq. 1 ) then
tst=(dm1-dm2)/sqrt((1.d0/ng1+1.d0/ng2)*(dss1+dss2)/(ng1+ng2-2))
return
endif
tst=(dm1-dm2)/sqrt(dss1/((ng1-1)*ng1)+dss2/((ng2-1)*ng2))
end
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