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15b1b4d9d69ff54955c9ea567aef0d56 *DESCRIPTION
28dad4492fcf2f517fc721fd2834f28b *LICENSE
9d1596c4ecb74f6e82bad5919d578475 *NAMESPACE
a5cda67b9ced5209c85a307dfb7b4184 *R/MutationalPatterns.R
f0fb8d17be3b1d5457ad374176326d5a *R/S4_class.R
13acc98f8820659474936feb66e1a1d0 *R/bin_mutation_density.R
b2017ab9bef124fe17b4f9b5b6c61808 *R/binomial_test.R
0a9ed432d2c884857728a9c522db3765 *R/calculate_lesion_segretation.R
bea69f68c18396be5bb11e523c109d0a *R/check_remove_muttypes.R
c46f872f5e3f79122f7e87d87fe22fbd *R/cluster_signatures.R
89ff6cd63844883b3225d8b76d8ebc06 *R/context_potential_damage_analysis.R
9c817473a60ced7d76dbacf432c9bfbf *R/convert_sigs_to_ref.R
70f24a4b5a5d1dd1715b02c29e725e6b *R/cos_sim.R
3d826df1c40e7b38724922106058fb58 *R/cos_sim_matrix.R
db746a9255690f566df64047fcc1e6f1 *R/count_dbs_contexts.R
b0a8f8e483d06428a0091a8f39e9a440 *R/count_indel_contexts.R
b0ea3365a3b0ad0ba9c2f947fb8b9d15 *R/count_mbs_contexts.R
80935d9c13f07b71ff12654058952aeb *R/determine_regional_similarity.R
f8118fecd413e5a3ffe3355087e68cf4 *R/enrichment_depletion_test.R
9cacedbb26c2812ab3ec2acdfb24f30b *R/extract_signatures.R
d36c514d9af06cecd0891b236a71e088 *R/fit_to_signatures.R
984a51278f4d53cd31410d887d0769b2 *R/fit_to_signatures_bootstrapped.R
cc95dd4c0e82ced4ba8e2d2ff6017d44 *R/fit_to_signatures_strict.R
4c7eee6edc4d49cb38ba3d2a28fca310 *R/genomic_distribution.R
299130f0757b1987a6481afb2dba7ba4 *R/get_dbs_context.R
e413e10f9830a8e55f1380fef197fa32 *R/get_indel_context.R
9e492881ff475f810d426c428a1a9472 *R/get_known_signatures.R
a48d682c3894ab7fb18509dfdcde3e01 *R/get_mut_type.R
a66a586962d00edfd654aaa538afbcce *R/get_ref_alt.R
9adb8903c195becece6f7ac3115dd425 *R/get_sig_start.R
f761270421ebf283a927be07d56edaaa *R/intersect_with_region.R
4ff678d028c5c7a2cb4d65b2f6d522d2 *R/lengthen_mut_matrix.R
2cab41bf4c1852a0e2ae8ab86a971140 *R/merge_signatures.R
3ee8064eb2f54d6afa062b1f4a414fd7 *R/mut_192_occurrences.R
ebc70f0878cdb1282dedb6432de8922a *R/mut_96_occurrences.R
bb4c5c9f9c64f1798effd965fbd6ffc9 *R/mut_context.R
a39eaf3a72c34740eb1d9fd5c373f55e *R/mut_matrix.R
ce91dfe7194f48eb1df7f7f1fd304f13 *R/mut_matrix_stranded.R
a1ff325f18342638b1faff4645cf13f2 *R/mut_strand.R
7df45c132866002bba8a84542b5dadeb *R/mut_type.R
dfc2cc3275d98a88e7bf66c41874498d *R/mut_type_occurrences.R
55d959d3b545df3bcdc0654b74cceb1d *R/mutations_from_vcf.R
82e2c0847a375557fb982b04111ffe58 *R/plot_192_profile.R
311959466b5dbf696ead09adcdd78d13 *R/plot_96_profile.R
e5b895ef5558d2ba53d57a39082b9f59 *R/plot_bootstrapped_contribution.R
ed9fc723b34f6169777b6a0067a009d8 *R/plot_compare_dbs.R
78d38b730c5030b0915607090afa1893 *R/plot_compare_indels.R
8737b6c0df75faebb7bebbf29436e121 *R/plot_compare_mbs.R
2ca3035cb3a7ded0d79a7d5f12f57dc2 *R/plot_compare_profiles.R
5b0d64fba1d81ebed8fd3445b87dd21f *R/plot_contribution.R
38842ece311c2ac4d344ee464169bb6e *R/plot_contribution_heatmap.R
2e8bc7ab6a4b591e6f61c13cdd15d9a4 *R/plot_correlation_bootstrap.R
9df6cd3976474fb1301c67ef3e3b7671 *R/plot_cosine_heatmap.R
c3c0606c08f89e412ca03a953b133395 *R/plot_dbs_contexts.R
bcb61dd0dd0f80c144514bd90e700e37 *R/plot_enrichment_depletion.R
971fa1ce4aee51731d93845d730e591b *R/plot_indel_contexts.R
dfb8994498fc3407541a744341dd0249 *R/plot_lesion_segregation.R
a425402863108b081122c12a3cafa6bd *R/plot_main_dbs_contexts.R
5265b0d56c4f95b8b066f571cf62f866 *R/plot_main_indel_contexts.R
dc0ed010f16781d8c3fd8799e38e5f2f *R/plot_mbs_contexts.R
978139141459fb63af8ff3a58c18fd95 *R/plot_original_vs_reconstructed.R
9340f61aad1c66cec7b95bafc76a7177 *R/plot_profile_heatmap.R
08712e363052c194b3642b9913a5e79f *R/plot_profile_region.R
fefc2136b495f21ab1037a442241696f *R/plot_rainfall.R
c24424893648a5edbe804c98642b462a *R/plot_regional_similarity.R
cbb65b3e1c69482733a7a94fef381bc3 *R/plot_river.R
bb90d9248fc9ed9f7037c7f40a4823b6 *R/plot_signature_strand_bias.R
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b4f6285ba94f863767fedb9164763c2b *R/read_vcfs_as_granges.R
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5567e03a8413f548c8c42be5e52a6820 *R/strand_bias_test.R
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a8fb4170f9341ead0b1558f7b975191f *R/strict_refit_backwards_selection_sample.R
3fa7ca7966044364251f5b17cf6c235f *R/strict_refit_best_subset_selection_sample.R
0a2a9abe0811ddaa87c72fdfc6441294 *R/type_context.R
0b8aced64ab1963957e470f2c01314a9 *README.md
9eb095eed600ea0b7b299f2c38599de9 *build/vignette.rds
3a94e27b48ef91a096aca728e41e584d *inst/CITATION
ed95998103c1f15eb33bec8675b89832 *inst/NEWS
b68621166816d647a5b0cb5c42dab4d8 *inst/doc/Introduction_to_MutationalPatterns.R
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7c8f99f154f53b8a8318684ebc679756 *inst/extdata/ReplicationDirectionRegions.bed
643092cb274fce36504f839500210821 *inst/extdata/blood-AC.vcf
fc7938084ce8fbe9847d01bf118aa490 *inst/extdata/blood-ACC55.vcf
150473517ba18e3aaf399c9b180c960b *inst/extdata/blood-BCH.vcf
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a2bfb21690d86ad4e607cd119854f3bc *inst/extdata/colon2-sample.vcf
95a608fddd72b1765036f927ad30e387 *inst/extdata/colon3-sample.vcf
1a050f99f58a0afc3a17158fde0e5b42 *inst/extdata/duplicate.vcf
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39f063623d16503183ee9dffee66e616 *inst/extdata/liver1-sample.vcf
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2a1f82ea11ac948eb739611bd45f8705 *inst/extdata/liver3-sample.vcf
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5e052965ee25f874cd1c9082ed37e694 *inst/extdata/signatures/dbs_SIGNAL_exposure.txt
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9e868e8eb41b0d2545ed168d034ba9c9 *inst/extdata/signatures/snv_COSMIC_v3.1_reference.txt
7aa849f8c84eb4c954caa1fa952c4f2c *inst/extdata/signatures/snv_COSMIC_v3.2_reference_GRCh37.txt
3ad8e301d492818d50fe78cc7efd066d *inst/extdata/signatures/snv_COSMIC_v3.2_reference_GRCh38.txt
3d1163b13da4633a8e89068f4ca5d28f *inst/extdata/signatures/snv_COSMIC_v3.2_reference_mm10.txt
5ad31ce61e64b1ab1098f7d05130fc52 *inst/extdata/signatures/snv_SIGNAL_exposure.txt
9ee9b09a6d6feb0fc153f30863ab9466 *inst/extdata/signatures/snv_SIGNAL_reference.txt
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8048639b0d0fbc89dbee8b06dccbd560 *inst/extdata/signatures/tsb_snv_COSMIC_v3.1_reference.txt
403c69dfa78265ce3243a98014517e43 *inst/scripts/Format_signatures.R
d2d6c11b0390efcc8ce234fc87d4875e *inst/scripts/create_example_dbs.R
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a45390662576f0de8ecc64eed8788ed0 *inst/scripts/create_example_mbs.R
99ae1839a18e69d389a3733a6527e800 *inst/scripts/create_example_regulatory_regions.R
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b8fdcf57371a5bf6fd32d9cdee1a48ff *inst/scripts/create_example_vcfs.R
634298b7a9cc0d3b65dc57ae3b8c0c14 *inst/states/CTCF_g_data.rds
d6b322652e615904701ef72e4c44459c *inst/states/blood_dbs_counts.rds
b0af1dc752f767eee9fa22d15df1da8a *inst/states/blood_grl.rds
d7d87ca79521e46264814bc1c5f67405 *inst/states/blood_grl_dbs.rds
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0bd14b1729b8f32696e25d1146bbfa5a *inst/states/blood_grl_mbs.rds
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84527f56cc8efd5e749947aa2cb37bb4 *inst/states/nmf_res_data.rds
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32153d317ebf2716b564915e2338fbe9 *inst/states/regional_sims.rds
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2291e790eb6bce62de3399b598f6dccd *man/cos_sim.Rd
5f25495d18a1c78ed7ecaf76e8b2639b *man/cos_sim_matrix.Rd
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8149c5255ea45212fcc3e1ce88ffd25f *man/fit_to_signatures.Rd
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