File: snv_SIGNAL_reference.txt

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r-bioc-mutationalpatterns 3.8.1%2Bdfsg-1
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Type	SubType	Ref.Sig.1	Ref.Sig.18	Ref.Sig.17	Ref.Sig.MMR1	Ref.Sig.2	Ref.Sig.MMR2	Ref.Sig.5	Ref.Sig.8	Ref.Sig.13	Ref.Sig.3	Ref.Sig.30	Ref.Sig.MIXED1	Ref.Sig.4	Ref.Sig.N1	Ref.Sig.PLATINUM	Ref.Sig.MIXED2	Ref.Sig.33	Ref.Sig.22	Ref.Sig.10	Ref.Sig.36	Ref.Sig.7	Ref.Sig.MIXED3	Ref.Sig.16	Ref.Sig.19	Ref.Sig.N2	Ref.Sig.9	Ref.Sig.N3	Ref.Sig.52	Ref.Sig.11	Ref.Sig.38	Ref.Sig.51	Ref.Sig.N4	Ref.Sig.N5	Ref.Sig.N6	Ref.Sig.N7	Ref.Sig.N8	Ref.Sig.N9	Ref.Sig.N10	Ref.Sig.N11	Ref.Sig.24	Ref.Sig.N12
C>A	ACA	0.014424897	0.039663568	0.00637246	0.001284897	0.006002773	0.005882954	0.019739892	0.032921356	0.003356392	0.015533816	0.013830937	0.015670115	0.04682925	0.012899661	0.011447837	0.006738098	0.016281902	0.006021869	0.001902081	0.020723959	0.006262534	0.017771279	0.021866685	0.009241122	0.014792234	0.010021618	3.15e-05	0.008820322	0.000469377	0.005780576	0.107243963	0.006371023	0.011393581	0.014382785	0.017835626	0.021710632	0.024486268	0.018063089	0.012342346	0.036434958	0.010891987
C>A	ACC	0.01036035	0.01854461	0.004075949	0.002134185	0.004070956	0.00415773	0.013059128	0.029356539	0.001664493	0.01265987	0.011539566	0.013070126	0.029542757	0.011574808	0.02769772	0.006090299	0.009136114	0.003532936	0.002917451	0.009412484	0.002922378	0.009488339	0.009292729	0.008472831	0.00975002	0.010686855	0.000158254	0.002813218	0.000412351	0.009140234	0.015638115	0.012161696	0.017159438	0.02444077	1.43e-05	0.018173942	0.006366784	0.004850377	0.008840874	0.025013522	0.003039543
C>A	ACG	0.001777193	0.002808569	0.000710741	0.000391244	0.001034174	0.000720844	0.004064594	0.00343817	0.000428548	0.002915952	0.002280034	0.002233557	0.008773817	0.001532721	0.000801583	0.000287848	0.003173583	0.00086402	0.000272854	0.001006201	0.000426252	0.001441559	0.001861149	0.001292161	0.001843706	0.000423156	5.79e-07	0.003517274	8.38e-23	0.000644632	0.005014373	0.000949701	0.00110475	0.00410138	0.000982929	0.006046024	0.000636381	0.003283158	0.003049168	0.020609851	0.000195396
C>A	ACT	0.006919449	0.021455244	0.004336829	0.003651353	0.004913786	0.005277364	0.011390656	0.031910368	0.002206603	0.01408726	0.007832207	0.01127388	0.029801079	0.010940326	0.01456919	0.005926141	0.008716289	0.004065566	0.013517199	0.018142018	0.004430271	0.008285931	0.013147835	0.002591406	0.009484738	0.00440782	0.003334786	0.006190007	0.000713875	0.006674443	0.026764976	0.008824336	0.008269632	0.012185469	0.008979608	0.006306418	0.008538074	0.007919809	0.005989167	0.022857117	0.00212135
C>A	CCA	0.007878841	0.030676377	0.006800031	0.0090416	0.005428057	0.005532568	0.016180226	0.028274123	0.002984855	0.017257815	0.010974994	0.016940582	0.067906964	0.009444998	0.022259265	0.00507578	0.017340807	0.006409783	0.0032296	0.04558057	0.0042737	0.014087737	0.015556767	0.011371845	0.005811961	0.000826151	0.003172242	0.033980545	0.000139099	0.262036595	0.022341866	0.007263846	0.030543318	0.003943616	0.02343996	0.033273837	0.008523135	0.011658367	0.00849187	0.042872721	0.005199849
C>A	CCC	0.00609309	0.009401066	0.003728333	0.016102525	0.003420718	0.006279424	0.009757373	0.029827696	0.002042639	0.015732682	0.006066245	0.015730553	0.060567881	0.007474964	0.020098314	0.001007986	0.010441401	0.005720769	0.001174457	0.015764115	0.004245667	0.007421407	0.010041393	0.00663658	0.002103397	0.003535716	0.002720618	0.006701617	0.000725064	0.030259159	0.003422638	0.011926068	0.005520484	1.83e-22	0.007541543	0.032082763	0.011852773	5.44e-06	0.0089695	0.034592023	0.002715682
C>A	CCG	0.001494001	0.003671027	0.000840997	0.002869608	0.000969024	0.001778862	0.002914727	0.002529387	0.000476191	0.002748845	0.002184585	0.001426928	0.011374843	0.001008289	0.002222965	0.00189376	0.003358358	0.00087801	0.0002721	0.00419719	0.0002447	0.001305572	0.002151493	0.000826307	0.000532651	0.000510869	4.15e-14	0.005327423	3.6e-05	0.038289953	0.001137755	0.003055901	0.001260751	0.001524283	1.47e-17	0.008022419	0.002179883	0.001490101	0.002043693	0.016427583	0.001250833
C>A	CCT	0.00749014	0.021051852	0.005346346	0.049362338	0.003906115	0.014550264	0.007562451	0.028300822	0.002279157	0.01118618	0.003749505	0.010774454	0.05024554	0.007725836	0.041156307	0.004756729	0.010023769	0.004902147	0.014978718	0.067141625	0.005941448	0.014492614	0.011280616	0.002924944	0.006061119	7.45e-06	0.007115757	0.00653819	0.000758135	0.101079182	0.008649499	8.2e-20	0.014098574	0.005382011	0.004610496	0.00866027	0.003991204	0.009910799	0.00670609	0.023252952	0.005973029
C>A	GCA	0.010094096	0.056279193	0.004624421	0.002016401	0.004088908	0.002743164	0.010099591	0.014067565	0.001857978	0.005052994	0.006149857	0.005751214	0.029772677	0.003219792	0.013637767	0.001821514	0.009606881	0.0054768	0.001575751	0.048517411	0.003144283	0.027412711	0.012597327	0.004050276	0.001826475	0.006079736	6.88e-14	0.001529957	7.36e-05	0.012708754	0.047544553	0.007146837	0.007657532	1.27e-06	0.01214469	0.006875714	4.37e-21	0.008589611	0.002719381	0.04904387	0.001742992
C>A	GCC	0.004972623	0.01338918	0.00305101	0.003981828	0.002379014	0.003485789	0.011575717	0.015202226	0.001303162	0.008988306	0.00525143	0.004753274	0.027221259	0.004194867	0.032489614	0.002845256	0.00682402	0.006306945	0.001814418	0.017078637	0.002269993	0.005869447	0.009126254	0.004219213	0.002625946	0.010131943	2.09e-05	0.002683186	0.00021676	0.006681934	0.008376135	0.006383735	0.006949757	0.013947858	0.000937257	0.001169638	0.000647974	0.003252063	7.48e-07	0.097713125	0.005261922
C>A	GCG	0.001856784	0.00433259	0.000421773	0.000871606	0.000736417	0.000398177	0.005032414	0.001446439	0.000332109	0.001455741	0.001716247	0.000521084	0.006931328	0.000906816	0.001331564	0.002106763	0.001711285	0.001593502	9.67e-05	0.002983557	0.000334995	0.002223743	0.001314621	0.000245338	0.000346963	1.98e-05	0.000303563	0.003495802	7.82e-22	0.002366225	0.003325722	1.17e-20	0.000514323	0.002802367	0.002090781	0.000609886	0.00191536	0.001758849	0.002153242	0.043043861	0.000807979
C>A	GCT	0.006439967	0.032868204	0.003549211	0.010207646	0.00341986	0.004038775	0.007456332	0.014901837	0.001665637	0.007696574	0.004056414	0.007817455	0.020783129	0.004782366	0.013085107	0.001219633	0.005666958	0.004788811	0.008939924	0.051793533	0.003246789	0.012656681	0.010673208	0.004018857	0.003325799	0.002074459	0.007871241	0.003543528	0.000335763	0.007552678	4.84e-06	0.006931016	0.007635675	1.83e-22	1.3e-20	1.6e-08	0.000146862	0.004897882	3.29e-11	0.043612062	0.004949691
C>A	TCA	0.009567119	0.044188914	0.006880467	0.002030962	0.020570183	0.004025773	0.012675454	0.017011064	0.031648801	0.006422586	0.00623836	0.013221597	0.039410463	0.007426551	0.015863225	0.011969737	0.01701143	0.005477944	0.053259617	0.139198583	0.005441681	0.013168824	0.019112712	0.00355503	0.01611587	0.039167237	0.015959732	0.270875833	0.000464261	0.018005912	0.013674533	0.012113653	0.006619023	0.011943313	0.011693558	0.010214861	0.000977978	0.000874541	0.020747145	0.028334425	0.022973333
C>A	TCC	0.008760595	0.026730763	0.004353825	0.004006145	0.00938158	0.003135735	0.015007954	0.019016436	0.014634733	0.014067473	0.010608596	0.013719779	0.040054771	0.004713631	0.017748653	0.011338863	0.016360879	0.005776235	0.006464387	0.053093587	0.003176517	0.006981944	0.013876565	0.005733912	0.006013212	0.005870822	7.23e-14	0.034502846	0.000948121	0.012267755	0.00044402	0.008022938	0.009870985	0.014761604	0.004723298	0.029794064	0.004163331	1.68e-14	0.024373669	0.051130668	0.011739761
C>A	TCG	0.001984224	0.005321697	0.000806092	0.000369899	0.00145418	0.00083581	0.002180894	0.001550551	0.00259923	0.001674777	0.001492175	0.00080708	0.005666642	0.000823514	0.001420317	0.001596464	0.002666594	0.000595958	0.00127353	0.009638718	0.000537471	0.001601191	0.001383588	0.000808691	0.000672042	0.001029088	0.00115228	0.069546831	4.05e-05	0.003416924	0.004710281	1.17e-20	0.000472108	0.000965739	0.002441556	0.006126283	0.002191075	0.000407036	0.0030708	0.014263182	0.001875735
C>A	TCT	0.014238252	0.075648016	0.00995476	0.011753232	0.014415168	0.009471179	0.009682263	0.020977811	0.0159948	0.006659819	0.00612619	0.017472808	0.041143849	0.01520289	0.019985703	0.020014348	0.016301918	0.007415336	0.36243077	0.213372887	0.003053434	0.028901095	0.022451197	0.004043258	0.021040009	0.025011194	0.026231958	0.034246037	0.000796371	0.039615009	3.96e-07	0.009369219	0.011656101	0.006740501	8.43e-08	1.14e-07	0.001892915	0.006467775	0.014696376	0.019043595	0.01189424
C>G	ACA	0.003698977	0.007423163	0.003305461	0.002915548	0.002595931	0.007238875	0.007313438	0.012001564	0.005005948	0.028530484	0.008180095	0.021081186	0.011423069	0.006943719	0.005150639	0.001798431	0.008458582	0.002447632	0.000496377	0.001309437	0.00423182	0.003786447	0.007924006	0.003586213	0.010852757	0.005103167	0.000644703	0.008187227	0.000414014	0.007055168	0.016241104	0.008364264	1.25e-15	0.00688728	0.009658342	0.005834666	0.02246988	0.008094471	0.00156962	0.007042825	0.007276488
C>G	ACC	0.002123279	0.004157429	0.001983961	0.001349936	0.001142073	0.004023589	0.004638931	0.006468831	0.001784423	0.014994354	0.005574894	0.011996958	0.004672706	0.004477167	0.003282515	0.002432736	0.00413842	0.000927992	0.000240255	0.000670707	0.002447554	0.003079539	0.004026307	0.002063119	0.006212926	0.001035345	0.001433934	0.006321527	0.000242227	0.007475977	0.004757316	0.008290288	0.003281954	0.007032534	0.007196893	0.006836836	0.004963063	0.004692597	0.001949691	0.006581974	0.012485767
C>G	ACG	0.000901024	0.002337691	0.000693093	0.000299867	0.000582719	0.000710156	0.001364642	0.001762063	0.000501877	0.008163439	0.001262251	0.003044473	0.001901522	0.000658958	0.000780044	0.000556966	0.000876898	0.000180857	1.24e-05	0.000167968	0.000191323	0.000747425	0.000644565	0.000133719	0.002146942	0.000213094	0.001352811	0.001897005	5.68e-05	1.58e-21	1.49e-12	1.17e-20	1.47e-15	0.004190541	0.001139974	0.002237263	0.001126088	0.00462348	1.18e-21	0.002128557	0.000337921
C>G	ACT	0.003678893	0.006009018	0.004013924	0.002739025	0.003183752	0.006580026	0.006468057	0.011523946	0.005158525	0.02574732	0.007809862	0.025928264	0.007482114	0.011059207	0.00722923	0.003125379	0.006052599	0.001636147	0.000308449	0.000614027	0.002303738	0.002890423	0.018785896	0.00311077	0.019893416	0.00252345	0.000445517	0.01109163	0.000271661	0.001040659	0.005438412	0.010329574	0.006754402	0.006030614	0.00647393	0.007286242	0.016104583	0.006542659	1.45e-06	0.003441948	0.021500104
C>G	CCA	0.001532915	0.003560183	0.002418598	0.000618316	0.002482122	0.002210023	0.00550118	0.008671504	0.004919722	0.018272362	0.005297531	0.014694202	0.008915851	0.002606648	0.003656897	0.002256163	0.00482244	0.001297611	6.53e-05	0.000343911	0.001978472	0.0015697	0.004917995	0.002367132	0.00428029	5.35e-13	2.27e-14	0.004298491	0.000199851	0.001595647	0.004308009	0.000342546	0.001133682	0.005945622	0.003135638	0.013249138	0.001271824	0.000379379	0.003075359	0.005225027	0.005447108
C>G	CCC	0.001842802	0.003302313	0.002434325	0.000529228	0.001160889	0.00238248	0.005936975	0.007609028	0.001813281	0.015453531	0.005803953	0.009828041	0.007976762	0.002038727	0.004893587	0.001050768	0.004533047	0.001167075	6.43e-05	0.000327036	0.001727182	0.002574356	0.00371414	0.001716665	0.002992217	6.81e-05	0.001525927	0.003375379	9.47e-05	0.001941037	0.007546557	0.004703007	1.84e-21	0.001190877	0.000798695	0.010704244	0.000421242	0.001258043	0.004427945	0.006591635	0.015114969
C>G	CCG	0.001024153	0.002273882	0.000830991	0.000322335	0.000406543	0.000272145	0.002370389	0.001437726	0.00045772	0.006787774	0.000725073	0.002445539	0.002411545	0.000925973	0.001145814	0.001243414	0.001264793	0.000261396	1.32e-05	7.5e-05	0.000548996	0.000502565	0.001416947	5.73e-05	0.000728455	0.000110042	0.000601244	6.61e-21	3.44e-05	0.001776115	9.75e-08	0.004487039	1.84e-21	0.003385101	0.000988862	0.004112525	0.000283041	0.000480436	0.000830812	0.000942102	0.001807398
C>G	CCT	0.002866224	0.004860646	0.003769028	0.00101847	0.003164344	0.002213925	0.008826617	0.010785442	0.006775154	0.023338604	0.006822503	0.021849098	0.007039135	0.0045181	0.011331655	0.002013404	0.003618296	0.001139696	9.8e-05	0.000537613	0.001755467	0.002438933	0.013872838	0.001723265	0.006675945	0.001622191	0.001053984	0.003496536	0.000258244	0.004554128	0.00310941	0.005494326	0.003106931	0.002178172	0.000509863	0.014948661	5.55e-10	0.00129982	0.002200447	0.001353668	0.027446838
C>G	GCA	0.001679884	0.002984123	0.001461494	0.001186987	0.001230577	0.002348623	0.003452908	0.005514932	0.002045883	0.01259904	0.00454716	0.008662983	0.005783362	0.002645564	0.002776739	0.001208314	0.003623936	0.00124482	0.000308005	0.001118406	0.002020529	0.00114727	0.002347425	0.000868851	0.002999081	0.002835297	0.003853897	0.005739738	9.24e-05	0.003608472	0.000903412	0.002287456	0.002238753	0.006034466	0.005435692	0.005054486	0.004699341	0.00578134	1.53e-15	0.007059031	0.00361982
C>G	GCC	0.002060115	0.001833048	0.001983372	0.002179007	0.00109776	0.00405544	0.00392441	0.00443525	0.001895708	0.011629594	0.004832067	0.009735245	0.005021101	0.003499776	0.014352027	0.001990828	0.002987861	0.001292031	0.000208342	0.001172536	0.001567773	0.001400061	0.005052593	0.001110133	0.006319985	3.33e-05	0.00452685	0.004830605	0.000163533	0.000890689	0.000992452	0.004128901	0.00308227	0.005059567	1.3e-20	0.001771751	0.0026037	0.004981787	0.001849649	0.010161206	0.004488002
C>G	GCG	0.000358083	0.001045574	0.00023992	0.00025097	0.000336206	0.000666947	0.000847577	0.000855175	0.000403677	0.003646145	0.000805177	0.001643339	0.002103619	0.000538577	6.92e-05	0.000229212	0.001010272	0.000354921	5.96e-06	2.9e-05	0.000201898	0.000346741	1.04e-06	0.000292246	0.000451089	0.000302024	0.000364282	0.001420659	2.28e-05	0.001546024	5.99e-05	0.001650716	1.84e-21	0.005016713	0.004393517	1.85e-08	0.00224533	0.001179328	1.61e-16	0.005677607	0.000796971
C>G	GCT	0.001576374	0.003366415	0.00219334	0.001513747	0.001739951	0.003707377	0.003390747	0.008096937	0.003574154	0.016999564	0.005484194	0.016429284	0.003917818	0.002378878	0.009536576	6.47e-10	0.001712194	0.000917412	0.000299788	0.000284813	0.001036951	0.001342629	0.008050446	0.001730353	0.008026244	8.1e-05	0.005884888	0.002726067	0.000163776	0.003703191	1.95e-20	0.002903132	5.19e-14	0.00353801	2.28e-11	0.004315183	0.008964963	0.004067761	2.32e-12	0.00384401	0.008570043
C>G	TCA	0.001947585	0.007133276	0.004757506	0.000694949	0.069586272	0.005584152	0.006834547	0.007340887	0.202333531	0.016839462	0.000993429	0.052386672	0.005709807	0.001438247	0.002193934	0.018587227	0.010510936	0.002860091	7.67e-05	0.000714262	0.002953405	0.016352524	0.004550722	0.001355362	0.016160598	3.71e-22	0.007327269	0.008723225	0.000639784	0.011436869	9.67e-08	0.01016677	0.004398972	1.83e-22	0.002470883	1.26e-07	0.004757333	0.008512093	0.007238749	0.008760986	0.000152977
C>G	TCC	0.002650912	0.005092455	0.002743805	0.001088183	0.015703203	0.002915355	0.006997672	0.010556632	0.044966869	0.022849099	0.006018143	0.029563015	0.006243759	0.003632053	0.002790147	0.008100722	0.006970559	0.002074738	8.23e-05	0.002182588	0.000729779	0.003228498	0.004475031	0.001101967	0.007957133	2.48e-19	0.004500686	0.003642079	0.000447551	0.0084415	0.012421446	0.004206606	0.004958528	0.004590008	0.005147201	0.00995244	0.003888041	0.004856593	0.003553616	0.008145893	0.014746926
C>G	TCG	0.000632859	0.0014129	0.000668016	0.000148333	0.002322118	0.000483958	0.00148662	0.00117108	0.008931307	0.004912099	0.00076197	0.003571664	0.000995793	0.000762283	0.000198143	0.001523337	0.000742959	0.000355447	1.68e-05	7.29e-22	0.000172887	0.000170466	0.001184321	0.001027172	0.001161957	3.71e-22	8.39e-05	0.001179481	8.38e-23	0.000727091	1.54e-21	0.000415165	0.00178359	0.00279896	1.3e-20	0.002163575	0.003781687	0.003118139	0.000951919	0.002094695	0.002317261
C>G	TCT	0.006951195	0.011644864	0.00761935	0.001763377	0.089200678	0.009523365	0.008455844	0.019939903	0.232696805	0.03495254	0.005018682	0.09095786	0.006310373	0.006726846	0.019323924	0.02902834	0.016649837	0.003397045	0.000241125	0.002135708	0.001003339	1.93e-09	0.040135211	0.004352446	0.039109944	0.001032601	0.008362785	0.009006897	0.000750142	0.020327696	2.88e-07	0.015075669	0.013000634	1.83e-22	0.002399067	0.003874122	0.017988173	0.005328726	0.006597311	0.009119868	0.021889933
C>T	ACA	0.023980035	0.019639365	0.008078989	0.034030836	0.010706685	0.00802152	0.020082785	0.017578665	0.004522123	0.018285631	0.064858322	0.011404315	0.014235895	0.014075389	0.011017504	0.028897828	0.013736078	0.002808344	0.001677194	0.011076848	0.009113536	0.025963041	0.006259306	0.027065684	0.008239691	0.00788471	2.46e-05	0.013770427	0.027425862	0.010908758	0.025546671	0.029505988	0.006826793	0.050389456	0.046213452	0.01653433	0.018573496	0.031799998	0.039592575	0.009501902	0.015264248
C>T	ACC	0.012477838	0.009758736	0.004146494	0.015633377	0.004116051	0.002340381	0.012236869	0.006549896	0.00183953	0.007961498	0.040475059	0.006110593	0.008661595	0.006627096	0.010167487	0.016274244	0.007275907	0.002777334	0.003718699	0.006016039	0.016889293	0.014381292	0.00828953	0.004754914	0.004332368	0.004944064	3.74e-06	0.004779717	0.119099203	0.004396973	0.010691968	0.016429463	0.006861046	3.11e-09	0.027496466	0.016386293	0.006926562	0.014731513	0.02436362	0.005145336	0.003848324
C>T	ACG	0.148615584	0.032435613	0.00886013	0.031807841	0.014106131	0.009509645	0.011433916	0.010378511	0.006305528	0.007799384	0.0191925	0.011336991	0.0044066	0.014905486	0.004726703	0.020210883	0.035583108	0.001710398	0.008643056	0.001325701	0.008700722	0.051109408	0.003062621	0.01978214	0.01381284	0.00645329	0.004057134	0.016044797	0.005925908	0.024950318	0.005137535	0.073320133	0.031095233	0.026746341	0.055391756	0.020289667	0.001693409	0.006858262	2.52e-07	0.001684202	0.002527893
C>T	ACT	0.014013347	0.015992536	0.005132523	0.014023184	0.006685628	0.004073554	0.012513179	0.016775684	0.002782326	0.016633134	0.042208214	0.012530477	0.012012126	0.016074029	0.008246278	0.017603355	0.009456032	0.002014715	0.006101354	0.004569574	0.015880194	0.020230507	0.013292296	0.024033569	0.007689282	0.003960646	0.000878762	0.008378278	0.091494253	0.006133622	0.003559711	0.017660993	0.011324693	0.021581444	0.021939567	0.013970768	0.023151088	0.037336304	0.016483406	0.005686694	0.011398959
C>T	CCA	0.015656367	0.016534727	0.007271911	0.008848714	0.01698687	0.005020885	0.020110469	0.007091755	0.006553707	0.014999271	0.052007866	0.011385761	0.015171534	0.011977881	0.020430146	0.033851311	0.011473561	0.00316836	0.000864186	0.007049243	0.052285927	0.021473899	0.008206305	0.082303546	0.007800138	0.00618885	8.86e-06	0.017598098	0.022478211	0.012138239	0.008863647	0.010632673	0.016663035	0.030173233	0.034641806	0.025525631	0.039205435	0.014397261	0.03756963	0.00981821	0.012452115
C>T	CCC	0.015513956	0.011647514	0.005455505	0.012490994	0.007271459	0.006904931	0.019931784	0.005736856	0.002585253	0.00944945	0.048117321	0.003167948	0.01118642	0.005878506	0.084300793	0.022402109	0.008805448	0.006563299	0.00148542	0.003748971	0.063086438	0.019698821	0.005855139	0.075406404	0.002336896	0.003619831	8.29e-11	0.007824089	0.123627264	0.01510794	0.014667056	0.024847103	0.014404656	0.007376624	0.009648857	0.019605308	0.010022603	0.010269343	0.022624059	0.008808008	0.015118577
C>T	CCG	0.085616748	0.024009862	0.006972199	0.023918689	0.010828774	0.008230177	0.008883165	0.003359794	0.00576691	0.008867696	0.012638717	0.007352941	0.005148902	0.009099084	0.006719077	0.016928234	0.028431284	0.002364071	0.002773792	0.001344959	0.010434751	0.035276871	4.21e-08	0.022733372	0.009249757	0.003023183	0.000754454	0.010917726	0.003349626	0.012944328	0.005671859	0.030117591	0.026367948	0.047241554	0.025189906	0.012615869	0.00569603	0.003753576	0.000461575	0.003090521	0.00106198
C>T	CCT	0.017362891	0.015150011	0.006386272	0.011832082	0.012684689	0.005144459	0.026906049	0.020227949	0.004856646	0.016726793	0.051228548	0.010829695	0.020323698	0.017654512	0.070802027	0.026343955	0.012142725	0.003471458	0.002423071	0.003130367	0.064657244	0.022128033	0.019781679	0.161236755	0.004435413	0.007254987	0.003421228	0.013753284	0.084572297	0.004767611	0.006022584	0.036435033	0.022731776	2.16e-14	0.042078796	0.001686489	0.003430674	0.03019374	0.004276822	0.009379419	0.0128655
C>T	GCA	0.017363605	0.012326489	0.005363632	0.042257071	0.008469265	0.003961656	0.017396696	0.006635345	0.004479235	0.011892319	0.038786454	0.010086233	0.009806187	0.006847587	0.016658005	0.016893927	0.010350571	0.003173286	0.002760905	0.008529864	0.008323678	0.017303871	0.010277552	0.042547549	0.004518409	0.003343477	0.000490044	0.007428775	0.024204165	0.01225856	9.87e-09	0.016648263	0.004862342	0.019745915	0.015582124	0.005527362	0.016696442	0.013208397	0.040204661	0.014997291	0.013593758
C>T	GCC	0.018887574	0.011896196	0.004205526	0.053504734	0.004439421	0.009584801	0.015107498	0.003663942	0.003822543	0.006985395	0.038321322	0.005708569	0.009917344	0.004013046	0.016909959	0.01468047	0.010218869	0.004355128	0.011862606	0.006827819	0.012869474	0.014372046	0.007910156	0.047110808	0.001298236	8.48e-16	0.011650131	0.00356432	0.095229144	0.009597189	0.008709558	0.01910759	0.00873815	3.75e-05	0.011338286	0.007190596	0.009053904	0.006629223	0.027434603	0.024939433	0.005192008
C>T	GCG	0.108039172	0.027920917	0.008292321	0.052453533	0.009316575	0.020905372	0.007344172	0.002660925	0.006880131	0.006604093	0.011238987	0.007878526	0.004095256	0.011532351	0.006763802	0.019732181	0.023329057	0.001723662	0.015314711	0.011586932	0.002774889	0.04155848	0.001575342	0.017002632	0.011142118	3.71e-22	0.016359529	0.014246133	0.004546578	0.024450111	2.41e-06	0.037315492	0.024113542	0.031065029	0.039889282	0.008249258	0.003647054	9.63e-07	0.000200529	0.003557817	0.000528868
C>T	GCT	0.017716085	0.013107066	0.004412378	0.038836482	0.007760437	0.006909706	0.015558139	0.009932665	0.003308671	0.009684597	0.042309189	0.009207844	0.009781733	0.009154691	0.013714414	0.014878339	0.009504082	0.003146868	0.014452417	0.003984827	0.018146649	0.014598975	0.014498618	0.080879158	0.003000148	1.18e-21	0.015848681	0.004439998	0.063746057	0.006764105	0.015187202	0.024377266	0.010971682	0.00101015	0.011274694	1.64e-05	0.01587834	0.012631107	0.006770847	0.015397051	0.008816487
C>T	TCA	0.015584213	0.013568263	0.011777315	0.010365868	0.26410684	0.007779782	0.013754557	0.014970758	0.15503811	0.002444905	0.029399266	0.033953867	0.009233036	0.008020579	0.013891232	0.152294793	0.03088439	0.003797367	0.003849956	0.007062614	0.137070423	0.077903585	0.001771208	0.026724457	0.017405104	1.8e-05	0.021206111	0.008571158	0.029005068	0.019927375	1.18e-09	0.019039869	0.040201413	0.029095126	0.015914181	0.018101461	0.028658757	0.011764256	0.051570093	0.0099605	0.025847142
C>T	TCC	0.018535078	0.018703326	0.009063331	0.013640555	0.063030281	0.007012995	0.018132013	0.009669619	0.027660569	0.010927382	0.049269175	0.013048967	0.012015213	0.009930285	0.028441799	0.082510335	0.016114281	0.003393748	0.011712627	0.006783118	0.20529892	0.039313477	0.01047823	0.011589113	0.008665489	0.003622582	0.009080928	0.007407166	0.153536589	0.017641153	0.01396317	0.013569018	0.05309419	0.012215324	0.005068013	0.020050227	0.006746972	0.014791845	0.040056876	0.013174528	0.007954059
C>T	TCG	0.060808434	0.017846839	0.004958592	0.012636613	0.032446384	0.005571651	0.005245875	0.003647707	0.017371135	0.005123944	0.007642085	0.005853259	0.001665211	0.007092704	0.006978272	0.021435629	0.015196228	8.48e-05	0.060629201	0.000591004	0.048030105	0.021617113	0.000417771	0.006015343	0.009455593	3.07e-07	0.000212251	0.011381822	0.003557157	0.016109766	0.006984742	0.021577448	0.036811649	0.032315755	0.016008671	0.010804624	0.0060973	0.00826445	0.000702683	0.005008822	0.000117063
C>T	TCT	0.017999732	0.018457958	0.011700191	0.013301468	0.151893953	0.006817367	0.01780426	0.017745462	0.064461685	0.009217919	0.032032774	0.029064728	0.013242767	0.021367766	0.016876191	0.126816634	0.025505804	0.00226992	0.03148955	0.011087157	0.10486298	0.057264153	0.017582319	0.030552991	0.012361631	0.003116652	0.01178263	0.004495017	0.122219488	0.020532564	0.045521686	0.020747377	0.024030438	0.018564596	0.045988869	0.006178766	0.034128915	0.020531087	0.034445461	0.006217691	0.008875282
T>A	ATA	0.006295069	0.006950144	0.00292614	0.013156528	0.00295074	0.013928297	0.014333584	0.014735004	0.002131512	0.004296507	0.005783862	0.006628771	0.008885453	0.040809533	0.004301696	0.006005136	0.010137471	0.058637061	0.000835786	0.004634586	0.004172097	0.003312082	0.013526595	0.004017045	0.012113876	0.012835289	0.000135321	0.008170139	0.000534813	0.004878709	0.051429601	0.014184123	0.016366412	0.026520462	0.030086158	3.17e-07	0.031846565	0.002914715	0.01910902	0.003343442	0.01023592
T>A	ATC	0.007256884	0.004473382	0.002502366	0.01334409	0.002026351	0.004086603	0.007912889	0.011821801	0.001374255	0.003971768	0.006448119	0.004517982	0.003717423	0.013293075	0.006242726	0.003157888	0.002492247	0.009213138	0.000387959	0.003052179	0.004321185	0.004620743	0.00659107	0.003630395	0.007643199	0.003048439	0.016600538	0.002213742	0.000122575	0.002478055	0.010149773	0.008291575	0.005684718	0.013745369	2.77e-17	0.003963409	0.007927449	0.009230457	0.00485732	0.004171334	0.006600991
T>A	ATG	0.005612001	0.004792316	0.001850007	0.0016051	0.00235547	0.004273862	0.01319972	0.016334713	0.001584671	0.007007613	0.008715077	0.007672987	0.008521181	0.019906256	0.003519898	0.005197052	0.005303138	0.051820481	0.000134708	0.000216725	0.002845658	0.004069997	0.008707277	0.004580079	0.007840687	0.00898309	0.001834888	0.004161089	0.000184456	0.00592511	0.041663232	0.009244255	0.003060989	0.009907299	0.012602794	0.021172168	0.004422431	0.014491425	0.001713764	0.002479077	0.010392721
T>A	ATT	0.013334757	0.019445585	0.007003097	0.019730306	0.003684784	0.022389796	0.011186578	0.018453864	0.003126852	0.004925229	0.007128773	0.008362531	0.007534453	0.044548414	0.004857711	0.013955135	0.007163785	0.017147653	0.005779601	0.022135855	0.009683128	0.0117037	0.010473727	0.001544571	0.017497542	0.015265624	0.006006649	0.006459031	0.000621748	0.005152244	0.01430532	0.013312923	0.007355349	0.026345951	0.003790146	0.00010553	0.010875341	0.020937305	0.00844759	0.002669816	0.01421256
T>A	CTA	0.001652991	0.003063295	0.002224158	0.001675941	0.001573221	0.003799186	0.006513874	0.014887613	0.000998625	0.009005533	0.003076999	0.005692442	0.00913249	0.013643552	0.026501487	0.002086585	0.00875705	0.100532437	0.000221525	0.003443211	0.003028485	0.002300604	0.004612238	0.00378372	0.012877368	0.005926536	0.000901299	0.001666254	0.000379846	8.54e-05	0.006769085	0.005664413	0.003785244	0.002807838	8.66e-05	7.99e-08	0.015794572	0.007713244	0.00611617	0.004575398	2.29e-06
T>A	CTC	0.002357924	0.003554851	0.009947223	0.003936584	0.001864147	0.004982762	0.00634147	0.019836216	0.001061987	0.00996707	0.00414926	0.007589736	0.00864751	0.01229052	0.020643195	0.002097755	0.005837322	0.047315456	0.000447551	0.001608865	0.003992962	0.005176709	0.005718535	0.004453738	0.006866634	2.02e-21	0.003771981	0.001036497	0.000192105	0.000999383	0.002676285	0.005802348	0.002681127	0.004761481	0.003021073	0.005819967	0.013517441	3.98e-05	0.000774248	0.003293974	0.008772097
T>A	CTG	0.002159158	0.002932931	0.004570548	0.001766516	0.002258119	0.004249511	0.010966814	0.020636837	0.001181209	0.011004722	0.003926457	0.007990907	0.015975871	0.008986574	0.027214105	0.002692454	0.007785005	0.144179957	0.000294516	0.001406623	0.00242943	0.004897857	0.00262209	0.001309721	0.006061004	0.008418769	0.000120074	0.003905898	0.000215693	0.003112059	0.005536417	1.41e-11	0.006730528	0.004272644	0.006141851	0.017291557	0.010638474	0.009445038	7.53e-06	0.012049042	0.005878893
T>A	CTT	0.0031061	0.007126548	0.023147854	0.001821073	0.002747039	0.004354946	0.008198825	0.031875121	0.001798819	0.015823027	0.005108333	0.012282345	0.009317106	0.021200301	0.037376052	0.002450747	0.007012094	0.044041967	0.00115204	0.00030015	0.003173071	0.009186524	0.006235792	0.004802689	0.022767423	9.63e-18	0.00050033	0.002411952	0.000517825	0.001836258	0.005816076	0.003935151	0.00806083	0.004732045	1.3e-20	0.001677738	0.005623991	0.014497449	0.00192891	0.009419636	0.005452961
T>A	GTA	0.001600361	0.002648313	0.001449409	0.002595685	0.001046092	0.004141447	0.006210971	0.01031459	0.000621601	0.005540095	0.00167016	0.003017539	0.006423755	0.013295296	0.002476338	0.002547028	0.004691645	0.042547186	0.000128694	0.002504597	0.000490161	0.00142415	0.001535845	0.001923164	0.005900849	0.002866724	4.02e-05	0.001244175	4.06e-05	0.000689518	0.008089701	0.002534935	0.003650451	0.008335287	0.005663613	0.005383193	0.003441011	0.011113326	0.003921989	0.002203361	0.004241938
T>A	GTC	0.002433668	0.002101048	0.00293901	0.006664546	0.001044546	0.002874965	0.003854438	0.007113051	0.000692518	0.004060391	0.003392031	0.0019103	0.002998225	0.008512163	0.004843291	0.000796696	0.001205303	0.009867298	0.000248465	0.000170563	0.002153176	0.001553822	0.002501681	0.000241703	0.005103991	3.71e-22	0.008719633	0.000740478	0.000289865	1.58e-21	0.001172	0.002999449	0.004898315	0.006346532	0.008729544	0.002722953	0.004837637	0.005862337	0.003552347	0.000953472	0.005225458
T>A	GTG	0.001973607	0.002782672	0.001873592	0.002480441	0.001209852	0.004297357	0.006605007	0.010618371	0.000856858	0.007101097	0.004108991	0.004969353	0.007769102	0.006999434	0.003846361	0.002068164	0.004710079	0.0332571	4.4e-05	0.000559075	0.001797249	0.002479711	0.003372809	0.001944146	0.004931552	0.000496745	2.65e-07	0.007174714	0.000205586	0.002318738	0.006016376	0.002896677	0.002197536	0.004356503	0.011544933	0.014475932	0.011323225	0.008330692	0.003381651	0.00412131	0.005339447
T>A	GTT	0.00229337	0.004947189	0.005995877	0.00348252	0.002206264	0.003351832	0.005014902	0.018851268	0.000907569	0.009326385	0.003949616	0.007352602	0.005771742	0.011011965	0.002588145	0.002865211	0.004105198	0.009418538	0.000734176	0.002863837	0.002550182	0.004744687	0.00156259	0.001783973	0.00640762	0.00327768	0.001712084	0.001268192	0.000341798	0.002090514	0.012051649	0.004796394	0.004788683	0.001893302	7.53e-05	0.005674451	0.003181392	0.013978447	0.002186828	0.000120645	0.005118103
T>A	TTA	0.009852331	0.014878378	0.00498447	0.009252842	0.002561285	0.013336486	0.010290129	0.011885262	0.002978973	0.011192703	0.001783593	0.007820733	0.0075469	0.04007806	0.004294518	0.012381705	0.008434928	0.071546623	0.001821045	0.016031504	0.006628331	0.014170745	0.00958705	0.005505737	0.029100009	0.027393641	0.008632413	0.00173052	0.000308837	0.002468455	0.008744865	0.022509084	5.68e-12	0.020698842	0.003375948	0.001970773	0.008048038	0.007629771	0.01550772	0.005095692	0.01611623
T>A	TTC	0.002568734	0.004919999	0.003928494	0.003395444	0.001464306	0.005064877	0.006809587	0.012934549	0.00087227	0.007930602	0.00413031	0.003881334	0.004717598	0.01194132	0.005018039	0.003613336	0.004248705	0.018304038	0.000777738	0.002700811	0.003127315	0.001366202	0.004763894	0.002879685	0.009348606	0.002651795	0.002641501	0.000464733	0.000159719	0.003688985	0.002523944	0.008955258	0.004552634	0.00629265	0.002742601	0.002469889	0.007535332	0.00285479	0.005046747	0.005591524	0.023310836
T>A	TTG	0.001526617	0.003006313	0.002375935	0.001278746	0.001467347	0.004019615	0.007183543	0.009465838	0.001084236	0.006067169	0.005142607	0.004112709	0.007155249	0.009432187	0.002845083	0.001507665	0.004239013	0.055423385	0.000861247	0.002624436	0.002171749	0.002884225	0.004225489	0.003514994	0.009714895	0.035520478	7.33e-20	0.002329475	0.00027	1.58e-21	0.004713139	0.009959261	0.006748833	0.004363179	1.3e-20	0.015348313	0.026025249	0.001926538	0.005025222	0.003856381	0.010061998
T>A	TTT	0.00614659	0.013956184	0.012916969	0.005801152	0.003083452	0.010729161	0.012904	0.030366496	0.002173577	0.014823849	0.007147906	0.011344875	0.009068172	0.032621973	0.006795857	0.007849123	0.007131851	0.027802808	0.006870365	0.00729875	0.007356729	0.009692143	0.002607042	0.006110771	0.031836206	0.016786855	0.001124572	0.005142671	0.000830427	0.001104125	0.002923266	0.022586099	0.012206162	0.015349977	0.010013885	0.009168233	0.009598982	0.007467698	0.006444441	0.002113742	0.048098648
T>C	ATA	0.017207032	0.011411217	0.008706261	0.027956301	0.005518201	0.056268225	0.057093817	0.011861436	0.003736417	0.011653682	0.019969496	0.018595572	0.016294756	0.033919803	0.012394594	0.006402149	0.021250164	0.024744257	0.007381218	0.009027932	0.00336671	0.005270146	0.147954718	0.026544354	0.030663112	0.029067219	0.014199833	0.01942338	0.000220394	0.008248369	0.017691234	0.018686319	0.015269935	0.036541495	0.043255522	0.043019695	0.044632722	0.033961607	0.052529367	0.015104281	0.023320104
T>C	ATC	0.006009588	0.004744947	0.00527455	0.010572319	0.002421137	0.024219141	0.011361591	0.006081571	0.001302776	0.010766206	0.006630716	0.007453	0.001638628	0.009920082	0.003512303	0.003462807	0.003897186	0.000808746	0.004368952	0.002764092	0.001580884	0.004625795	0.011406829	0.003863254	0.003758512	0.009620965	0.015572685	0.008872757	0.000733869	0.003383218	0.006751311	0.006884018	0.006686812	0.007740685	0.008053371	0.012916983	0.024616051	0.030611238	0.004768878	0.001496206	0.00546765
T>C	ATG	0.009269186	0.005756728	0.005138301	0.024187411	0.003700885	0.040575936	0.034145807	0.007849261	0.002515863	0.01049021	0.016356398	0.013841272	0.006758421	0.012350586	0.007045456	0.003479623	0.038956594	0.007658194	0.003316882	0.005854062	0.001514381	0.003993892	0.043026918	0.019079684	0.005279189	0.019764924	0.014718898	0.010422851	7.53e-17	0.007210535	0.005691014	0.014335725	0.011846903	0.003991604	0.016962571	0.088337891	0.019081864	0.002548916	0.012857033	0.000209975	0.015963255
T>C	ATT	0.017383171	0.012672255	0.010246787	0.012632289	0.005519921	0.03157679	0.036754866	0.015578661	0.004682015	0.019428699	0.020367551	0.017396406	0.009452502	0.033719285	0.010880151	0.009611592	0.010323277	0.00341132	0.006964821	0.007061764	0.003291636	0.006665949	0.079702033	0.015079846	0.010026332	0.024156524	0.015502577	0.021859151	0.000998491	0.007462647	0.007237515	0.015078996	0.018493193	0.019123434	0.028569644	0.040213917	0.039684132	0.022255443	0.013242052	0.005990846	0.024655202
T>C	CTA	0.004441309	0.004356208	0.009328734	0.019473228	0.000961217	0.032481393	0.016118651	0.005768324	0.001577314	0.010784781	0.007334034	0.005616307	0.007500614	0.008208552	0.008333501	0.005605645	0.012741427	0.006715777	0.001105538	0.002545483	0.003005128	0.003297436	0.018379566	0.003230178	0.028539639	0.01412956	0.005114681	0.012935762	0.000371925	0.002276444	2.98e-13	0.005319541	0.007903751	0.006487968	0.009821269	0.013610042	0.035138435	0.026211962	0.018923691	0.006482117	0.017274864
T>C	CTC	0.004771179	0.005200983	0.029852079	0.010239545	0.001708455	0.028516206	0.008422653	0.012351709	0.001947916	0.014117644	0.007093488	0.010200688	0.005228655	0.007260022	0.007219366	0.005488621	0.016315161	0.003016349	0.001712992	0.001186213	0.001208042	0.006857633	0.00655723	0.002256805	0.006389015	0.006971506	0.011232517	0.006335165	0.000668115	0.001037295	0.033299003	0.006226556	0.008215002	0.011228642	0.021573417	0.007723547	0.036704794	0.008408738	0.00199094	0.002769596	0.004375421
T>C	CTG	0.00475539	0.004260548	0.021310002	0.025798522	0.001850096	0.038358214	0.013037545	0.004908096	0.00091079	0.009056752	0.008273236	0.005633344	0.006001523	0.001855452	0.009196474	0.003081284	0.018803669	0.003048093	0.001284193	0.0004633	0.00250058	0.004532953	0.009795367	0.005863175	0.00072209	0.01473538	0.009438554	0.004222313	2.51e-20	0.006334921	0.001097173	0.008224605	0.00627501	0.008543183	0.01173205	0.035111591	0.002881184	0.002192786	0.009725938	0.001756561	0.008571151
T>C	CTT	0.005821303	0.007116031	0.077175944	0.014936411	0.002357035	0.032670317	0.011258184	0.010469902	0.00251076	0.013967344	0.006829236	0.011454945	0.006242718	0.014039307	0.017043853	0.005588564	0.005950903	0.001231299	0.002397377	0.001493926	0.007849615	0.017536762	0.019827532	0.006479023	0.008458656	0.012582501	0.003400585	0.011869819	0.00036543	0.004344236	0.004272235	0.010137591	0.016337554	0.009241237	0.01285769	0.004498537	0.012831872	0.040031862	0.006653047	0.007804099	0.003769336
T>C	GTA	0.008746194	0.005254788	0.004435781	0.041076873	0.001488373	0.047801963	0.021650837	0.004010276	0.002343461	0.004494982	0.004430138	0.005676988	0.00469362	0.014778546	0.003237284	0.002525543	0.012064356	0.004189789	0.009113948	0.005674277	0.001902571	0.006537351	0.010223922	0.006560457	0.014721132	0.005613136	0.012092224	0.010946642	0.00148576	0.004573637	2.24e-10	0.008221669	0.017142622	0.019612617	0.000454532	0.007576036	0.006267319	0.024951882	0.061369672	0.004837588	0.012029163
T>C	GTC	0.006952243	0.003217198	0.006820265	0.014719859	0.001408101	0.022752294	0.009354731	0.003730395	0.002072764	0.0063988	0.003302139	0.005742164	0.001004535	0.012225677	0.008072002	0.003819882	0.003490873	0.002072784	0.008492324	0.003991801	0.000263899	0.004970378	0.002786386	0.001859144	0.003767724	0.002498742	0.03976495	0.008047779	0.000867443	0.000239729	0.001582149	0.003371032	0.008616908	0.013189616	0.000521922	0.002697334	0.015153077	0.013008582	0.008145064	0.005576407	0.003255491
T>C	GTG	0.005777141	0.002238526	0.005967463	0.026891844	0.001645156	0.033881267	0.011227726	0.00419824	0.001350688	0.004922759	0.005393716	0.006998467	0.002945237	0.006136311	0.001997157	0.001144261	0.070925681	0.002141554	0.003664624	0.002096211	0.000507022	0.0027033	0.006487338	0.004768703	0.000633751	0.006370348	0.019476245	0.002667887	0.000446973	0.004030319	0.003912683	0.002337616	0.005466655	0.012276136	0.005450413	0.027548216	0.004007961	0.001182077	0.010511939	6.39e-09	0.008374378
T>C	GTT	0.009513287	0.00644378	0.011169577	0.025099821	0.003311206	0.033179858	0.019362099	0.006289811	0.002632256	0.00919906	0.008383864	0.00760001	0.003562896	0.025635502	0.004522607	0.003824269	0.006656245	0.001222052	0.014179736	0.006237627	0.01421296	0.004024542	0.006683249	0.014323471	0.005007936	0.000199364	0.016787801	0.012700722	0.00096147	0.011142862	0.005242399	0.004276367	0.069591066	0.01782078	0.011225344	0.012468235	0.020321758	0.026569974	0.033810851	0.005287934	0.006113288
T>C	TTA	0.007313486	0.007046627	0.008844844	0.029350072	0.002961968	0.043084961	0.026071686	0.005433392	0.002460524	0.013490508	0.006250112	0.007301453	0.006578311	0.019316805	0.00235802	0.005277042	0.011406606	0.008579286	0.007322665	0.004729805	0.006694816	0.002426061	0.025422527	0.008145851	0.076421129	0.016666216	0.003475991	0.013288646	0.000360271	0.007808456	3.39e-13	0.007846705	0.012884244	0.021649814	0.010354125	0.015166339	0.012749917	0.036591408	0.067779269	3e-05	0.017411165
T>C	TTC	0.006756379	0.008509373	0.010224342	0.016207723	0.001831029	0.033355003	0.010676345	0.008002946	0.001761617	0.014664892	0.0037138	0.008494197	0.001885595	0.021850526	0.002248019	0.005974466	0.00626958	0.00082561	0.007809353	0.007846305	0.00145375	0.006426401	0.003999903	0.00193411	0.010651771	0.008032387	0.042260135	0.006596448	0.000544321	0.00290755	0.004896462	0.002442467	0.009930895	0.021740101	0.008601752	1.85e-06	0.012919593	0.027459739	0.007782498	0.005013589	0.006904935
T>C	TTG	0.004482034	0.003337211	0.007037465	0.016429964	0.001155088	0.026315923	0.011637783	0.002645679	0.000837705	0.004446722	0.003681109	0.005197601	0.002920038	0.003719505	0.00330974	0.001747679	0.111641319	0.00483091	0.004506953	0.00350419	0.003634387	0.000957129	0.007910726	0.006552553	0.012611839	0.010174741	0.008002148	9.9e-05	0.000328626	0.006127183	0.002340685	0.006077192	0.003300683	0.008722209	0.002551076	0.02771681	6.85e-13	0.001222398	0.015573792	0.00040126	0.008626702
T>C	TTT	0.011612847	0.010745462	0.015938337	0.026438795	0.003640667	0.046570137	0.019771046	0.007639338	0.001737329	0.013501815	0.005855306	0.009961421	0.005098898	0.034039759	0.005209217	0.008466753	0.00892061	0.000939309	0.011937317	0.008204968	0.006478412	0.012243488	0.011026902	0.012483357	0.01704844	0.02916707	0.007341303	0.007490042	0.000612884	0.005121164	0.015029348	0.007900708	0.019430642	0.022155515	0.020676323	0.000226477	0.037235423	0.030557674	0.02991762	0.00527178	0.012106078
T>G	ATA	0.002430468	0.002943198	0.004665909	0.001085642	0.001261844	0.006553682	0.004858474	0.0041876	0.001070344	0.006480227	0.003459947	0.006771886	0.002624877	0.018843578	0.002694188	0.003234399	0.002390162	0.004840594	0.004363255	0.003201915	0.000607229	0.001442547	0.010292673	0.005894703	0.022893595	0.078046946	0.009937283	0.005620233	0.000163708	0.000167169	0.010939904	0.015477738	0.007394074	0.00453314	1.99e-14	0.000145751	0.01200708	0.017803096	0.010345716	0.004578426	0.014781332
T>G	ATC	0.001441099	0.001551906	0.005178415	0.001433073	0.000801001	0.003991743	0.002386795	0.000922883	0.000283177	0.002739373	0.001770809	0.002160903	0.000722598	0.004375801	0.00185979	0.00043171	0.001334128	0.000279995	0.003567186	0.001272421	0.000351631	0.000825513	0.002469382	0.002185383	0.001863309	0.006986099	0.004364052	0.002160859	8.38e-23	0.000743583	0.004733245	0.005722054	0.003119223	0.001269098	1.3e-20	0.002412082	0.006122372	0.005742369	0.00165978	0.002374874	0.018702076
T>G	ATG	0.002309302	0.003024764	0.003196714	0.001060273	0.001103062	0.002980505	0.004044485	0.006044875	0.000989244	0.009493459	0.003608161	0.006378355	0.001909153	0.004136692	0.003757144	0.002126851	0.002800726	0.003571832	0.001779813	3.83e-05	0.003356634	0.002163454	0.003907399	0.004180482	0.00536289	0.008323091	0.006444136	0.003127531	4.59e-05	0.006077762	0.017485303	0.005567853	0.032845308	0.01091182	0.010945965	0.004963552	0.005782197	0.009456357	1.15e-05	0.005206118	0.01573056
T>G	ATT	0.003245299	0.004062222	0.042507926	0.002693838	0.000961264	0.006549153	0.00492232	0.001473829	0.001144573	0.00652613	0.00560161	0.003945551	0.001411075	0.004438128	0.003284982	0.010055709	0.003013842	0.001759853	0.029465882	0.002541823	0.001431708	0.01056302	0.007224253	0.001174679	0.007287469	0.021482433	0.028049014	0.008291184	0.000230822	0.002582344	0.007541867	0.001994674	0.004353115	0.005540942	0.003307739	0.002859273	0.018286349	0.010765594	0.0075713	0.006530288	0.043626323
T>G	CTA	0.001396977	0.001480295	0.004119919	0.000850493	0.000454219	0.003929213	0.003253292	0.001825588	0.000678304	0.006427911	0.001439864	0.004914012	0.000826387	0.005503093	0.002381067	0.000365348	0.004996151	0.003996126	0.003457548	0.000359486	0.000701729	0.002588233	0.002249997	0.000952092	0.011432018	0.041019229	0.024996144	0.004311956	8.38e-23	1.58e-21	0.005042838	0.010717812	0.003768128	0.002169107	2.82e-05	0.004669804	0.000621804	0.000567122	0.001309253	0.000961569	0.007214138
T>G	CTC	0.00127719	0.001052826	0.016417068	0.003918232	0.000941348	0.005419656	0.003121917	0.00281555	0.000502787	0.005683314	0.001909397	0.00350054	0.000634588	0.002973842	0.001670405	0.001682097	0.002021986	0.001089491	0.00129443	0.000740588	0.000476744	0.002397165	0.003250404	0.001381794	0.003528444	8.38e-05	0.011628882	0.001579439	4.71e-22	0.001244376	1.16e-12	0.003993562	0.002527353	0.001746258	1.3e-20	0.010393478	0.003396614	0.001026628	0.003204753	0.000714253	0.012318648
T>G	CTG	0.002304649	0.001928382	0.009537247	0.004814529	0.001351197	0.007170329	0.004623455	0.006744432	0.00068732	0.010937667	0.002651748	0.007358023	0.002718145	0.003381802	0.003618739	0.002547938	0.002214345	0.010184251	0.002278568	0.001023763	0.002797623	0.002962802	0.004561633	0.001448624	0.003673154	0.016580991	0.024164873	0.001853986	8.38e-23	0.00268725	0.01204372	0.001909152	0.012964357	0.007102152	0.004905159	0.010893119	0.001485368	0.001161769	4.98e-12	0.001660659	0.008575638
T>G	CTT	0.004383898	0.003288263	0.198848261	0.004450678	0.001888119	0.004000255	0.003662833	0.003225293	0.000895393	0.007657011	0.000696638	0.001350405	0.000696799	0.000838096	0.002454272	0.002936089	0.002546824	0.001182024	0.016675261	0.000561614	0.001204634	0.045858774	0.001237274	0.000870062	0.021856232	0.017875845	0.100252343	0.000286476	0.000197929	0.003440313	3.48e-17	0.002155318	0.000262679	0.003820199	0.002722667	1.58e-08	0.002124443	2.03e-08	0.003065803	0.011910702	6.35e-06
T>G	GTA	0.001149828	0.001061193	0.00154486	0.000570163	0.000213007	0.002040828	0.001686785	0.002191606	0.000273548	0.005019035	0.001447436	0.002828203	0.000844973	0.005359765	0.001430987	0.002373197	0.00165142	0.001858737	0.001027115	0.000208098	0.000619921	0.001222586	0.002073996	0.00035673	0.004518531	0.009472196	0.007879153	0.003351742	4.84e-05	0.000920227	0.005943646	0.002245941	0.005830996	0.001994028	0.006875248	0.00377327	0.001931141	0.010398795	0.002216189	0.000641648	0.003091745
T>G	GTC	0.001121381	0.000749113	0.004055561	0.001396471	0.000376792	0.002288155	0.00164034	0.00148222	0.000330144	0.002959193	0.000889266	0.001682694	0.000378984	0.00201585	0.004169211	7.81e-05	0.001168173	0.000529321	0.001648929	2.73e-05	0.000199025	0.000807358	0.001114265	0.000762651	0.001968922	0.006854575	0.012041604	0.002703945	6.58e-05	0.001082063	0.005074652	0.002999382	0.001293882	0.000561926	0.003202083	0.002666745	0.001414742	0.006225456	0.000688359	0.000852506	0.003726348
T>G	GTG	0.002444798	0.002213094	0.003482538	0.001515547	0.000896388	0.003028105	0.00298539	0.005884197	0.0010817	0.008703466	0.002658857	0.007039633	0.0023593	0.000897118	0.004679705	0.003009247	0.009761394	0.002622231	0.000858299	0.000102934	0.003618538	0.003341189	0.002309676	0.001617791	0.002346785	0.004267795	0.016393379	0.004500177	8.62e-05	0.003951768	0.107789549	0.008752956	0.039208948	0.017835727	0.076742075	0.006944593	0.00934303	0.004713191	1.18e-21	0.001919132	0.00599909
T>G	GTT	0.002845832	0.001969807	0.048174873	0.005899129	0.000947418	0.005167412	0.003006501	0.003204865	0.001159645	0.00671724	0.000402498	0.003041526	0.000639931	0.003352013	0.002048565	0.01086734	0.0015424	0.000759891	0.004724404	4.1e-13	0.002246008	0.012611769	0.002389192	0.001538689	0.001701261	0.008420657	0.122743468	0.003224711	0.000167138	0.00114519	0.00618814	0.001298025	0.006374164	0.004635479	1.3e-20	0.001456413	0.004320452	0.009184222	0.00175985	0.003604916	0.003253674
T>G	TTA	0.00239181	0.003051083	0.007430345	0.00108636	0.001549186	0.003962434	0.004690214	0.002802871	0.001790613	0.011561751	0.002341487	0.009088864	0.001786581	0.015313354	0.00243961	0.002516271	0.002610569	0.004062553	0.015675771	0.006605101	0.001300062	0.001328988	0.008771188	0.003688132	0.045680425	0.13480451	0.032037865	0.002634151	5.21e-05	0.000219461	0.002701545	0.051991405	0.006038695	0.005561127	1.3e-20	0.003670827	0.005288607	0.013824509	0.005667107	0.002891373	0.018558435
T>G	TTC	0.002223353	0.001704809	0.008703154	0.001177826	0.001016435	0.002111053	0.004408527	0.002820459	0.000989086	0.006379557	0.002468176	0.005511816	0.000843234	0.006999164	0.002456998	0.001904097	0.002347987	0.000693436	0.006562187	3.52e-05	0.000678114	0.001620311	0.004788011	0.002914429	0.011115239	0.010010646	0.003265051	0.004259419	0.000252643	0.000827989	0.006789231	0.002108212	0.001048865	0.00449262	0.000786414	0.005141735	0.00609998	0.015425299	0.002593839	0.004942231	0.029724849
T>G	TTG	0.002442636	0.004103109	0.006448291	0.00177777	0.001184236	0.004778961	0.005267858	0.006131816	0.001002264	0.012098625	0.003111939	0.009146816	0.002992192	0.007837387	0.003761505	0.00112029	0.00224888	0.00579966	0.002760308	0.001329298	0.003270744	0.002896028	0.004085563	0.001117469	0.010604865	0.018158163	0.008153031	0.006813083	0.000264952	0.001168136	0.006602352	0.006079483	0.010973135	0.009287899	0.005486325	0.007066619	0.00675384	0.019457926	0.001916031	0.004465908	0.018152499
T>G	TTT	0.007561992	0.008461636	0.088536299	0.00399569	0.003057441	0.009520456	0.011337466	0.005763461	0.002322117	0.013727913	0.006255612	0.009046765	0.002783903	0.013214228	0.006178701	0.016390801	0.003879281	0.002075235	0.131147297	0.013675186	0.004505503	0.021835918	0.013348485	0.002499274	0.049396894	0.076196655	0.090711554	0.012533249	0.000244499	0.003397369	0.01289806	0.017250653	0.008273057	0.009184654	0.003613755	0.002723556	0.012473484	0.022261493	0.009188995	0.00987134	0.053164906